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公开(公告)号:US20050214294A1
公开(公告)日:2005-09-29
申请号:US11057323
申请日:2005-02-11
申请人: Allan Flyvbjerg , Guangjie Guo , David Liu , Thomas Neff , Noelynn Oliver , William Usinger , Qingjian Wang
发明人: Allan Flyvbjerg , Guangjie Guo , David Liu , Thomas Neff , Noelynn Oliver , William Usinger , Qingjian Wang
IPC分类号: A61K31/00 , A61K38/00 , A61K38/55 , A61K39/395 , C07K16/22
CPC分类号: A61K38/556 , A61K31/00 , A61K39/395 , A61K2039/505 , C07K16/22 , A61K2300/00
摘要: The present invention relates to methods and compounds for treating specific early stage aspects and late stage aspects of diabetic nephropathy. Methods and compounds for treating various physiological features associated with early stage and with late stage diabetic nephropathy are also provided.
摘要翻译: 本发明涉及用于治疗糖尿病肾病的特异性早期方面和晚期方面的方法和化合物。 还提供了用于治疗与早期和晚期糖尿病肾病相关的各种生理特征的方法和化合物。
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公开(公告)号:US20060183695A1
公开(公告)日:2006-08-17
申请号:US11405734
申请日:2006-04-17
申请人: Stephen Klaus , Al Lin , Thomas Neff , Qingjian Wang , Volkmar Guenzler-Pukall , Michael Arend , Lee Flippin , Alex Melekhov
发明人: Stephen Klaus , Al Lin , Thomas Neff , Qingjian Wang , Volkmar Guenzler-Pukall , Michael Arend , Lee Flippin , Alex Melekhov
IPC分类号: A61K38/04 , A61K31/502
CPC分类号: A61K31/4745 , A61K31/00 , A61K31/17 , A61K31/4375 , A61K31/44 , A61K31/4418 , A61K31/47 , A61K31/472 , A61K31/4738 , A61K31/496 , A61K31/63 , A61K38/1709 , C07K14/4702 , C07K14/505 , G01N33/746
摘要: The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
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公开(公告)号:US20060258660A1
公开(公告)日:2006-11-16
申请号:US11495036
申请日:2006-07-28
申请人: Volkmar Guenzler-Pukall , Thomas Neff , Qingjian Wang , Michael Arend , Lee Flippin , Alex Melekhov
发明人: Volkmar Guenzler-Pukall , Thomas Neff , Qingjian Wang , Michael Arend , Lee Flippin , Alex Melekhov
IPC分类号: A61K31/502
CPC分类号: A61K31/4745 , A61K31/00 , A61K31/17 , A61K31/4375 , A61K31/44 , A61K31/4418 , A61K31/47 , A61K31/472 , A61K31/4738 , A61K31/496 , A61K31/63 , A61K38/1709 , C07K14/4702 , C07K14/505 , G01N33/746
摘要: The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
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公开(公告)号:US20060178317A1
公开(公告)日:2006-08-10
申请号:US11406484
申请日:2006-04-17
申请人: Stephen Klaus , Al Lin , Thomas Neff , Qingjian Wang , Volkmar Guenzler-Pukall , Michael Arend , Lee Flippin , Alex Melekhov
发明人: Stephen Klaus , Al Lin , Thomas Neff , Qingjian Wang , Volkmar Guenzler-Pukall , Michael Arend , Lee Flippin , Alex Melekhov
IPC分类号: A61K38/04 , A61K31/4745
CPC分类号: A61K31/4745 , A61K31/00 , A61K31/17 , A61K31/4375 , A61K31/44 , A61K31/4418 , A61K31/47 , A61K31/472 , A61K31/4738 , A61K31/496 , A61K31/63 , A61K38/1709 , C07K14/4702 , C07K14/505 , G01N33/746
摘要: The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
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公开(公告)号:US20060258702A1
公开(公告)日:2006-11-16
申请号:US11495118
申请日:2006-07-28
申请人: Volkmar Guenzler-Pukall , Thomas Neff , Qingjian Wang , Michael Arend , Lee Flippin , Alex Melekhov
发明人: Volkmar Guenzler-Pukall , Thomas Neff , Qingjian Wang , Michael Arend , Lee Flippin , Alex Melekhov
IPC分类号: A61K31/47
CPC分类号: A61K31/4745 , A61K31/00 , A61K31/17 , A61K31/4375 , A61K31/44 , A61K31/4418 , A61K31/47 , A61K31/472 , A61K31/4738 , A61K31/496 , A61K31/63 , A61K38/1709 , C07K14/4702 , C07K14/505 , G01N33/746
摘要: The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
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公开(公告)号:US20060270699A1
公开(公告)日:2006-11-30
申请号:US11494978
申请日:2006-07-28
申请人: Volkmar Guenzler-Pukall , Thomas Neff , Qingjian Wang , Michael Arend , Lee Flippin , Alex Melekhov
发明人: Volkmar Guenzler-Pukall , Thomas Neff , Qingjian Wang , Michael Arend , Lee Flippin , Alex Melekhov
IPC分类号: A61K31/4745
CPC分类号: A61K31/4745 , A61K31/00 , A61K31/17 , A61K31/4375 , A61K31/44 , A61K31/4418 , A61K31/47 , A61K31/472 , A61K31/4738 , A61K31/496 , A61K31/63 , A61K38/1709 , C07K14/4702 , C07K14/505 , G01N33/746
摘要: The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.
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公开(公告)号:US20060178316A1
公开(公告)日:2006-08-10
申请号:US11406023
申请日:2006-04-17
申请人: Stephen Klaus , Al Lin , Thomas Neff , Qingjian Wang , Volkmar Guenzler-Pukall , Michael Arend , Lee Flippin , Alex Melekhov
发明人: Stephen Klaus , Al Lin , Thomas Neff , Qingjian Wang , Volkmar Guenzler-Pukall , Michael Arend , Lee Flippin , Alex Melekhov
CPC分类号: A61K31/4745 , A61K31/00 , A61K31/17 , A61K31/4375 , A61K31/44 , A61K31/4418 , A61K31/47 , A61K31/472 , A61K31/4738 , A61K31/496 , A61K31/63 , A61K38/1709 , C07K14/4702 , C07K14/505 , G01N33/746
摘要: The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
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公开(公告)号:US20130282179A1
公开(公告)日:2013-10-24
申请号:US13992377
申请日:2011-12-01
IPC分类号: B25J13/06
CPC分类号: B25J13/06 , A61B34/30 , A61B34/35 , B25J9/1689 , G05B2219/40147 , G05B2219/40195 , G05B2219/45119 , G06F19/00 , G06F19/3418 , G06F19/3481 , G16H20/00 , G16H50/20
摘要: The invention relates to a telepresence system (1) with a human-machine interface (2), and with a teleoperator (3) designed to communicate bid sectionally with the human-machine interface (2) via a communications channel (4).
摘要翻译: 本发明涉及一种具有人机接口(2)的远程呈现系统(1),以及经由通信信道(4)与人机接口(2)进行部分通信的远程操作器(3)。
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公开(公告)号:US20050171430A1
公开(公告)日:2005-08-04
申请号:US10997293
申请日:2004-11-23
申请人: Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Cupples , Thomas Neff , Michael Reed
发明人: Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Cupples , Thomas Neff , Michael Reed
CPC分类号: A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要: Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译: 描述了在交互式用户界面上显示乳房超声信息,用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中,乳头标记被显示为表示其上的乳头位置的突起的冠状厚片图像。 还显示方便的胸部图标,包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地,乳房图标被配置为至少大致类似于时钟面,时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。
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公开(公告)号:US09902072B2
公开(公告)日:2018-02-27
申请号:US13992377
申请日:2011-12-01
CPC分类号: B25J13/06 , A61B34/30 , A61B34/35 , B25J9/1689 , G05B2219/40147 , G05B2219/40195 , G05B2219/45119 , G06F19/00 , G06F19/3418 , G06F19/3481 , G16H20/00 , G16H50/20
摘要: A telepresence system includes a man-machine interface and a teleoperator configured to communicate bidirectionally with the man-machine interface via a communications channel. The teleoperator performs actions based on first signals generated due to a manual operation of the man-machine interface and transmitted over the communication channel, and sends second signals to the man-machine interface over a second communication channel. At least one buffer device buffers signals transferred through the communication channel and releases the signals delayed so that the signals coming from the man-machine interface and the signals coming from the teleoperator each are transmitted through the communication channel with an effective constant time delay.
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