摘要:
A new process for preparing 3-alkyl-3-cephem-4-carboxylic acids of the general formula: ##STR1## wherein R.sub.1 is amino or a substituted amino, R.sup.2 is carboxy or a protected carboxy and R.sup.3 is a lower alkyl, andNew intermediates of the general formula: ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are each as defined above and Y' is a residue of ammonia or a saturated aliphatic amine or a secondary cyclic amine, comprises reacting a compound of the formula ##STR3## wherein X is a residue of a thiol compound, with a condensing agent or a polar solvent, or with ammonia or an amine, respectively. In the latter case, the resultant new intermediate may further be reacted with a condensing agent or a polar solvent to form a 3-alkyl-3-cephem-4-carboxylic acid as above.
摘要:
An oxazetidine derivative compound of the formula: ##STR1## wherein R.sub.1 represents a substituted or unsubstituted amino radical and R.sub.3 represents a radical selected from the group consisting of carboxy, protected carboxy, ester, acid amide, acid anhydride, acid halide, acid azide and carboxy salt, and --SR.sub.2 is a residue of a thiophilic sulphur nucleophile.
摘要:
A process for producing a 2-cephem or 3-cephem derivative compound of the formula: ##SPC1##Wherein R.sub.1 represents a substituted or unsubstituted amino radical and R.sub.4 represents hydrogen or a radical selected from the group consisting of carboxy, protected carboxy, ester, acid amide, acid anhydride, acid halide, acid azide and carboxy salt, and the dotted line indicates the alternate bond structure providing 3-cephem or 2-cephem, which comprises:Reacting a halogenated derivative selected from the group consisting of a halogenated penam derivative having the formula: ##SPC2##A halogenated cepham derivative of the formula: ##SPC3##Wherein X represents a halogen atom, R.sub.3 represents a radical selected from the group consisting of carboxy, protected carboxy, ester, acid amide, acid anhydride, acid halide, acid azide and carboxy salt, and R.sub.1 is as defined above, or mixtures thereof with a dehydrohalogenoic acid reagent.
摘要:
A process for the preparation of ##SPC1##Which comprises reacting ##SPC2##With a base, wherein Y is a residue of an acid, wherein R.sup.1 is amino, (halophenylimino-1-lower alkanoylthiomethyl)amino or acylamino and wherein R.sup.2 is carboxy or a protected carboxy, R.sup.3 is lower alkyl, R.sup.4 is lower alkylene and X is --S-- or ##EQU1##
摘要:
A capacitor (114) is provided between a power supply line (111a) and a ground line (111b), which connect a power supply connector (130) connected to a high voltage power supply (140) and a power element (118). A current detection unit (113) for detecting positive current flowing in the direction from the high voltage power supply (140) to the power element (118) and negative current flowing in the opposite direction is provided on the power supply line (111a). A load resistor (112) is provided between the current detection unit (113) and the power supply connector (130). When the current value detected by the current detection unit (113) becomes less than zero, a control unit (116) detects that the connection of the high voltage power supply (140) has released.
摘要:
When a material shape model is separated in shear through processing, a shape model of a material in a state of being suspended remains in mid-air, and thus, interference is detected excessively. In order to prevent the excessive detection of interference, in a processing simulation method for generating a shape model of a processed material from a shape model of a material and a shape model of a tool processing area which is defined from a shape model of the tool and a movement path of the tool, the shape model of the material being separated into a plurality of shapes by processing is detected; a material shape to be cut-off is extracted from the separated material shapes; and the extracted material shape to be cut-off is excluded from subject of simulation.
摘要:
Even in an uncuttable state in which an actual rotational direction of a main spindle is not matched with an actually cuttable main spindle rotational direction of a tool, an interference check between a workpiece and the tool is performed. Accordingly, the cuttable main spindle rotational direction of the selected tool or the uncuttable main spindle rotational direction is compared with each main spindle rotational direction of a working machine during execution of a simulation, and it is determined whether an interference check between the tool blade edge and the workpiece is necessary on the basis of the comparison result. When it is determined that the interference check is not necessary in the step above, the interference check between the tool blade edge and the workpiece is not performed. When it is determined that the interference check is necessary, the interference check between the tool blade edge and the workpiece is performed. When the interference therebetween is present, abnormality is detected.
摘要:
A card edge connector for electrically connecting harnesses to contact electrodes that are located in different positions on a surface of an electronic substrate in an insertion direction includes a housing, harness terminals, and relay terminals. The housing defines a substrate insertion hole for receiving the electronic substrate. The harness terminals are separately connected to the harnesses and located in different positions in a height direction perpendicular to the insertion direction. The relay terminals separately connect the harness terminals to the contact electrodes upon insertion of the electronic substrate into the substrate insertion hole.
摘要:
A card edge connector for electrically coupling between contact electrodes on an electric circuit board and harnesses includes: a housing with a board insertion opening; harness terminals coupling with the harnesses; and junction terminals coupling between contact electrodes and harness terminals. The contact electrodes include first and second contact electrodes on both of first and second surfaces of the board. Each first contact electrode is nearer one end of the board than each second contact electrode. The first and second contact electrodes on the first or second surface are aligned alternately along with a width direction of the board. A first or second end of the junction terminal contacting the contact electrode on the first or second surface extends from a first or second inner wall of the board insertion opening to reach a centerline of the board.