Automated nanoassembly
    77.
    发明授权

    公开(公告)号:US07297946B2

    公开(公告)日:2007-11-20

    申请号:US11205201

    申请日:2005-08-16

    IPC分类号: G01N13/16 G01B5/88 G01B7/34

    CPC分类号: B82B3/00 G01Q30/04 G01Q80/00

    摘要: An automated nanomanipulation system is provided for manufacturing a nanoscale structure. The system includes: a design model for the nanoscale structure; image data of a sample surface upon which the nanoscale structure is to be manufactured; a movable member configured to perform a nanomanipulation operation on the sample surface; and a path planning subsystem adapted to receive the design model and the image data. The path planning subsystem generates path data indicative of a path for traversing the movable member along the sample surface such that the movable member manipulates one or more randomly distributed nanoobjects in accordance with the design model.

    Vanilloid receptor ligands and their use in treatments
    78.
    发明授权
    Vanilloid receptor ligands and their use in treatments 失效
    香草素受体配体及其在治疗中的应用

    公开(公告)号:US07265138B2

    公开(公告)日:2007-09-04

    申请号:US10775980

    申请日:2004-02-09

    IPC分类号: A61K31/425 C07D277/04

    摘要: Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

    摘要翻译: 具有一般结构和含有它们的组合物的化合物,用于治疗急性,炎性和神经性疼痛,牙痛,一般头痛,偏头痛,丛集性头痛,混合血管和非血管综合征,紧张性头痛,一般炎症,关节炎,风湿性 疾病,骨关节炎,炎症性肠病,炎症性眼病,炎症性或不稳定性膀胱病,银屑病,皮肤炎症成分炎症,慢性炎性病症,炎性疼痛及相关的痛觉过敏和异常性疼痛,神经性疼痛及相关的痛觉过敏和异常性疼痛,糖尿病性神经病疼痛, 咳嗽痛,交感神经痛,交感综合征,哮喘,上皮组织损伤或功能障碍,单纯疱疹,呼吸系统内脏运动紊乱,泌尿生殖道,胃肠道或血管区,伤口,烧伤,过敏性皮肤反应,瘙痒,白癜风,一般胃肠道疾病, G 腹部溃疡,十二指肠溃疡,腹泻,坏死因子诱发的胃损伤,毛发生长,血管舒缩或过敏性鼻炎,支气管疾病或膀胱疾病。

    Process and apparatus for modifying a surface in a work region
    79.
    发明申请
    Process and apparatus for modifying a surface in a work region 有权
    用于修改工作区域中的表面的工艺和设备

    公开(公告)号:US20060284118A1

    公开(公告)日:2006-12-21

    申请号:US11452891

    申请日:2006-06-14

    IPC分类号: H01J37/08

    CPC分类号: H01J37/32366 H01J37/32357

    摘要: An apparatus and process for manufacturing changes of a substrate in a work region which is 100×100×100 microns or smaller is described. The apparatus uses a plasma source adjacent to the work region to produce radiation or matter which changes the surface. An atomic force microscope or laser can be used in addition. The process and apparatus can be used to produce MEMS devices on a substrate for use in a wide variety of applications.

    摘要翻译: 描述了用于制造100×100×100微米或更小的工作区域中的衬底的变化的装置和工艺。 该设备使用与工作区域相邻的等离子体源产生改变表面的辐射或物质。 另外还可以使用原子力显微镜或激光。 该方法和装置可用于在基板上制造用于各种应用的MEMS器件。

    Active sensor for micro force measurement
    80.
    发明申请
    Active sensor for micro force measurement 失效
    用于微力测量的主动传感器

    公开(公告)号:US20060196280A1

    公开(公告)日:2006-09-07

    申请号:US11366014

    申请日:2006-02-27

    申请人: Ning Xi Yantao Shen

    发明人: Ning Xi Yantao Shen

    IPC分类号: G01L1/10

    CPC分类号: G01L1/08

    摘要: An active micro-force sensor is provided for use on a micromanipulation device. The active micro-force sensor includes a cantilever structure having an actuator layer of piezoelectric material and a sensing layer of piezoelectric material bonded together. When an external force is exerted on the sensor, the sensor deforms and an applied force signal is recorded by the sensing layer. The applied force signal is then fed back to the actuating layer of the sensor via a servoed transfer function or servo controller, so that a counteracting deformation can be generated by the bending moment from the servoed actuating layer to quickly balance the deformation caused by the external micro-force. Once balanced, the sensor beam comes back to straight status and the tip will remain in its equilibrium position, thus the sensor stiffness seems to be virtually improved so that the accurate motion control of the sensor tip can be reached, especially, at the same time, the micro-force can also be obtained by solving the counteracting balance voltage applied to the actuating layer.

    摘要翻译: 提供用于显微操作装置的主动微力传感器。 有源微力传感器包括具有压电材料的致动器层和压电材料的感测层结合在一起的悬臂结构。 当外力施加在传感器上时,传感器变形,施加的力信号由传感层记录。 所施加的力信号然后通过伺服传递函数或伺服控制器反馈到传感器的致动层,使得可以通过来自伺服致动层的弯矩产生抵消变形,以快速平衡由外部引起的变形 微力。 一旦平衡,传感器光束返回到直线状态,并且尖端将保持在其平衡位置,因此传感器刚度似乎被实际改善,使得可以达到传感器尖端的精确运动控制,特别是同时 ,也可以通过求解施加到致动层的抵消平衡电压来获得微力。