公开(公告)号：US09034934B1

公开(公告)日：2015-05-19

申请号：US13483475

申请日：2012-05-30

Applicant: Yosry A. Attia

Inventor： Yosry A. Attia

IPC: C08J9/00 ,  C08J9/28 ,  C08J9/33

CPC classification number: C08J9/00 ,  C08J9/28 ,  C08J9/33 ,  C08J2201/0482 ,  C08J2201/0524 ,  C08J2205/026 ,  C08J2323/04 ,  C08J2323/06 ,  C08J2323/08

Abstract: A method for making polyethylene aerogels, including high molecular weight aerogels, commences by in a hydrocarbon solvent (e.g., toluene or benzene) in which polyethylene is insoluble at room temperature, adding polyethylene to the solvent heated to a temperature at which said polyethylene is soluble to form a reaction mixture. A free-radical catalyst is added to the reaction mixture and the reaction mixture is held until the desired gelation of the polyethylene has been achieved. The reaction mixture is cooled to about room temperature; and the hydrocarbon solvent is replaced with a gas (e.g., CO2 or air) to form the polyethylene aerogel. Optionally, the cooled reaction mixture can be contacted with an anti-solvent for polyethylene to replace the hydrocarbon solvent with the anti-solvent. Silica aerogel particles can be encapsulated in polyethylene aerogel by adding the particles to the polyethylene gelation reaction mixture.

Abstract translation: 制造聚乙烯气凝胶的方法，包括高分子量气凝胶，在烃溶剂（如甲苯或苯）中开始，其中聚乙烯在室温下不溶解，加入聚乙烯加热到所述聚乙烯可溶的温度 以形成反应混合物。 向反应混合物中加入自由基催化剂，并保持反应混合物，直至达到所需的聚乙烯凝胶化。 将反应混合物冷却至约室温; 并且用气体（例如CO 2或空气）代替烃溶剂以形成聚乙烯气凝胶。 任选地，冷却的反应混合物可与用于聚乙烯的反溶剂接触以用抗溶剂代替烃溶剂。 通过将颗粒加入到聚乙烯凝胶化反应混合物中，可以将二氧化硅气凝胶颗粒包封在聚乙烯气凝胶中。

公开(公告)号：US20120097884A1

公开(公告)日：2012-04-26

申请号：US13320800

申请日：2010-05-18

Applicant: Brigitte Jamart-Gregoire ,  Nicolas Brosse ,  Quoc Nghi Pham ,  Danielle Barth ,  Alexandre Scondo ,  Alain Degiovanni

Inventor： Brigitte Jamart-Gregoire ,  Nicolas Brosse ,  Quoc Nghi Pham ,  Danielle Barth ,  Alexandre Scondo ,  Alain Degiovanni

IPC: E04B1/78 ,  C07D221/06

CPC classification number: C08J9/28 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2203/08 ,  C08J2205/026 ,  C08J2389/00

Abstract: Material for thermal insulation including an aerogel obtained by drying an organogel prepared from the pseudopeptides of formula (I). in which R represents a side chain of an amino acid, R1 represents a (C1-C8)alkyl, (C1-C8)alkoxy, aryl, aryloxy, or glycoside group, n=1 or 2 and A represents an aromatic group with one or more rings.

Abstract translation: 包括通过干燥由式（I）的假肽制备的有机凝胶得到的气凝胶的绝热材料。 其中R表示氨基酸的侧链，R1表示（C1-C8）烷基，（C1-C8）烷氧基，芳基，芳氧基或糖苷基，n = 1或2，A表示芳基， 或更多的戒指。

公开(公告)号：US20110269859A1

公开(公告)日：2011-11-03

申请号：US12910244

申请日：2010-10-22

Applicant: Kuo-Chung CHENG ,  Yu-Shun Luo ,  Ching-Lin Wu ,  Chiu-Ya Wang ,  Yi-Min Chang

Inventor： Kuo-Chung CHENG ,  Yu-Shun Luo ,  Ching-Lin Wu ,  Chiu-Ya Wang ,  Yi-Min Chang

IPC: C08J9/28 ,  B05D3/10

CPC classification number: C08J9/28 ,  B01D67/0011 ,  B01D67/0013 ,  B01D71/46 ,  B01D2325/02 ,  C08J2201/0482 ,  C08J2205/02 ,  C08J2205/05 ,  C08J2363/00

Abstract: The present invention relates to a process for manufacturing a porous epoxy network, especially a porous epoxy membrane. The process according the present invention comprises the steps of: providing a reactant solution comprising an epoxy resin, a solvent and a curing agent; performing a first curing process to transform the reactant solution to a gel; and performing a second curing process to essentially remove the remaining solvent and transform the gel to form a porous epoxy network with open pores; wherein the curing agent is a tertiary amine.

Abstract translation: 本发明涉及多孔环氧网络的制造方法，特别是多孔环氧树脂膜。 根据本发明的方法包括以下步骤：提供包含环氧树脂，溶剂和固化剂的反应物溶液; 执行第一固化过程以将反应物溶液转变成凝胶; 并执行第二固化过程以基本上除去剩余的溶剂并转化凝胶以形成具有开孔的多孔环氧网络; 其中固化剂是叔胺。

公开(公告)号：US20100074930A1

公开(公告)日：2010-03-25

申请号：US12627963

申请日：2009-11-30

Applicant: Younan Xia ,  Sang Hyuk Im ,  Unyong Jeong

Inventor： Younan Xia ,  Sang Hyuk Im ,  Unyong Jeong

IPC: A61K9/50 ,  C08J3/00 ,  C08K9/00 ,  A61K8/11

CPC classification number: C08J3/12 ,  C08F6/14 ,  C08F112/08 ,  C08J9/28 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2325/04 ,  C08J2333/12 ,  Y10T428/2998 ,  C08L25/06 ,  C08F2/18

Abstract: A method for making a hollow polymer particle having a single, substantially circular opening in its surface.

Abstract translation: 一种制造中空聚合物颗粒的方法，所述中空聚合物颗粒在其表面具有单个基本圆形的开口。

公开(公告)号：US07553923B2

公开(公告)日：2009-06-30

申请号：US11925635

申请日：2007-10-26

Applicant: Simon F. Williams ,  David P. Martin ,  Frank A. Skraly

Inventor： Simon F. Williams ,  David P. Martin ,  Frank A. Skraly

IPC: C08G63/08

CPC classification number: A61L27/58 ,  A61F2/07 ,  A61F2210/0004 ,  A61K31/715 ,  A61L17/12 ,  A61L27/18 ,  A61L31/06 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00 ,  C08G63/06 ,  C08J9/26 ,  C08J2201/0444 ,  C08J2201/0482 ,  C08J2367/04 ,  C08K5/0033 ,  C08L67/04 ,  C12P7/625 ,  Y10S606/911

Abstract: Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including interference screws), bone plates and bone plating systems, surgical mesh, repair patches, slings, cardiovascular patches, orthopedic pins (including bone filling augmentation material), adhesion barriers, stents, guided tissue repair/regeneration devices, articular cartilage repair devices, nerve guides, tendon repair devices, atrial septal defect repair devices, pericardial patches, bulking and filling agents, vein valves, bone marrow scaffolds, meniscus regeneration devices, ligament and tendon grafts, ocular cell implants, spinal fusion cages, skin substitutes, dural substitutes, bone graft substitutes, bone dowels, wound dressings, and hemostats. The polyhydroxyalkanoates can contain additives, be formed of mixtures of monomers or include pendant groups or modifications in their backbones, or can be chemically modified, all to alter the degradation rates. The polyhydroxyalkanoate compositions also provide favorable mechanical properties, biocompatibility, and degradation times within desirable time frames under physiological conditions.

公开(公告)号：US20080051490A1

公开(公告)日：2008-02-28

申请号：US11836615

申请日：2007-08-09

Applicant: Simon Williams ,  David Martin ,  Frank Skraly

Inventor： Simon Williams ,  David Martin ,  Frank Skraly

IPC: C08G63/00 ,  A61K31/715 ,  A61K38/18 ,  A61K9/00

CPC classification number: A61L27/58 ,  A61F2/07 ,  A61F2210/0004 ,  A61K31/715 ,  A61L17/12 ,  A61L27/18 ,  A61L31/06 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00 ,  C08G63/06 ,  C08J9/26 ,  C08J2201/0444 ,  C08J2201/0482 ,  C08J2367/04 ,  C08K5/0033 ,  C08L67/04 ,  C12P7/625 ,  Y10S606/911

Abstract: Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including interference screws), bone plates and bone plating systems, surgical mesh, repair patches, slings, cardiovascular patches, orthopedic pins (including bone filling augmentation material), adhesion barriers, stents, guided tissue repair/regeneration devices, articular cartilage repair devices, nerve guides, tendon repair devices, atrial septal defect repair devices, pericardial patches, bulking and filling agents, vein valves, bone marrow scaffolds, meniscus regeneration devices, ligament and tendon grafts, ocular cell implants, spinal fusion cages, skin substitutes, dural substitutes, bone graft substitutes, bone dowels, wound dressings, and hemostats. The polyhydroxyalkanoates can contain additives, be formed of mixtures of monomers or include pendant groups or modifications in their backbones, or can be chemically modified, all to alter the degradation rates. The polyhydroxyalkanoate compositions also provide favorable mechanical properties, biocompatibility, and degradation times within desirable time frames under physiological conditions.

公开(公告)号：US20070111002A1

公开(公告)日：2007-05-17

申请号：US11493862

申请日：2006-07-25

Applicant: Younan Xia ,  Sang Im ,  Unyong Jeong

Inventor： Younan Xia ,  Sang Im ,  Unyong Jeong

IPC: B32B15/02

CPC classification number: C08J3/12 ,  C08F6/14 ,  C08F112/08 ,  C08J9/28 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2325/04 ,  C08J2333/12 ,  Y10T428/2998 ,  C08L25/06 ,  C08F2/18

Abstract: A hollow polymer particle having a single, substantially circular opening in the particle's surface, methods for making and using the polymer particle.

Abstract translation: 在颗粒表面具有单个基本圆形的开口的中空聚合物颗粒，制备和使用聚合物颗粒的方法。

公开(公告)号：US06281257B1

公开(公告)日：2001-08-28

申请号：US09292896

申请日：1999-04-16

Applicant: Peter X. Ma ,  Ruiyun Zhang

Inventor： Peter X. Ma ,  Ruiyun Zhang

IPC: C08J926

CPC classification number: C08J9/28 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2367/00 ,  C12N5/0068 ,  C12N2533/12 ,  C12N2533/18 ,  C12N2533/30 ,  C12N2533/40 ,  G01N15/14

Abstract: Methods and compositions are described that provide three dimensional porous matrices as structural templates for cells. The porous matrices of the present invention have desirable mechanical properties suitable to a variety of applications, including platforms for in vitro cell cultivation, implants for tissue and organ engineering, and materials suitable for chromatography and filtration.

Abstract translation: 描述了提供三维多孔基质作为细胞结构模板的方法和组合物。 本发明的多孔基质具有适合于各种应用的理想的机械性能，包括用于体外细胞培养的平台，用于组织和器官工程的植入物，以及适用于色谱和过滤的材料。

公开(公告)号：US4717800A

公开(公告)日：1988-01-05

申请号：US031675

申请日：1987-03-30

Applicant: Makoto Suzuki

Inventor： Makoto Suzuki

IPC: C08L29/04 ,  A61F2/08 ,  A61F2/68 ,  B25J9/00 ,  B25J9/10 ,  C08F8/00 ,  C08J9/28 ,  C08L29/02 ,  B01D39/14

CPC classification number: C08J9/28 ,  A61F2/08 ,  A61F2/68 ,  B25J9/0012 ,  B25J9/1095 ,  A61F2002/0894 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2201/0502

Abstract: An expansible macromolecular material is produced by a method which comprises mixing an aqueous polyvinyl alcohol solution, an acidic aqueous macromolecular electrolyte solution, and a basic aqueous macromolecular electrolyte solution thereby preparing a composite polymer and subjecting this composite polymer to at least one cycle of alternate freezing and defrosting treatments. A macromolecular membrane constituted of said expansible macromolecular material and containing numerous through holes is obtained by mixing, freezing, and defrosting the aforementioned three mixed aqueous solutions under specific conditions.

Abstract translation: 通过包括将聚乙烯醇水溶液，酸性高分子电解质水溶液和碱性高分子电解质水溶液混合从而制备复合聚合物并使该复合聚合物经受至少一个交替冷冻循环的方法制备可膨胀的高分子材料 和除霜治疗。 通过在特定条件下混合，冷冻和除霜上述三种混合水溶液，获得由所述可膨胀大分子材料构成并含有许多通孔的高分子膜。

公开(公告)号：US4673695A

公开(公告)日：1987-06-16

申请号：US785436

申请日：1985-10-08

Applicant: James H. Aubert ,  Roger L. Clough ,  John G. Curro ,  Carlos A. Quintana ,  Edward M. Russick ,  Montgomery T. Shaw

Inventor： James H. Aubert ,  Roger L. Clough ,  John G. Curro ,  Carlos A. Quintana ,  Edward M. Russick ,  Montgomery T. Shaw

IPC: B01D39/16 ,  B01D67/00 ,  B01D71/28 ,  C08J9/26 ,  C08J9/28

CPC classification number: C08J9/28 ,  B01D39/1676 ,  B01D67/003 ,  B01D71/28 ,  C08J9/26 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2201/052 ,  C08J2325/06

Abstract: Low density, microporous polymer foams are provided by a process which comprises forming a solution of polymer and a suitable solvent followed by rapid cooling of the solution to form a phase-separated system and freeze the phase-separated system. The phase-separated system comprises a polymer phase and a solvent phase, each of which is substantially continuous within the other. The morphology of the polymer phase prior to and subsequent to freezing determine the morphology of the resultant foam.Both isotropic and anisotropic foams can be produced. If isotropic foams are produced, the polymer and solvent are tailored such that the solution spontaneously phase-separates prior to the point at which any component freezes. The morphology of the resultant polymer phase determines the morphology of the resultant foam and the morphology of the polymer phase is retained by cooling the system at a rate sufficient to freeze one or both components of the system before a change in morphology can occur. Anisotropic foams are produced by forming a solution of polymer and solvent that will not phase separate prior to freezing of one or both components of the solution. In such a process, the solvent typically freezes before phase separation occurs. The morphology of the resultant frozen two-phase system determines the morphology of the resultant foam.The process involves subjecting the solution to essentially one-dimensional cooling. Means for subjecting such a solvent to one-dimensional cooling are also provided.Foams having a density of less than 0.1 g/cc and a uniform cell size of less than 10 .mu.m and a volume such that the foams have a length greater than 1 cm are provided.

Abstract translation: 通过包括形成聚合物溶液和合适溶剂的方法提供低密度，微孔聚合物泡沫，然后快速冷却溶液以形成相分离系统并冷冻相分离系统。 相分离系统包括聚合物相和溶剂相，其各自在另一个内基本连续。 在冷冻之前和之后的聚合物相的形态决定所得泡沫的形态。 可以生产各向同性和各向异性泡沫。 如果产生各向同性泡沫，则定制聚合物和溶剂使得溶液在任何组分冻结的点之前自发相分离。 所得聚合物相的形态决定了所得泡沫体的形态，并且通过以足以在形态变化发生之前冻结体系的一个或两个组分的速率冷却系统来保留聚合物相的形态。 通过形成聚合物和溶剂的溶液来产生各向异性泡沫，该溶液在溶液的一个或两个组分冷冻之前不会相分离。 在这种过程中，溶剂通常在相分离发生之前冻结。 所得冷冻两相体系的形态决定所得泡沫的形态。 该方法包括使溶液基本上进行一维冷却。 还提供了使这种溶剂进行一维冷却的方法。 具有小于0.1g / cc的密度和小于10μm的均匀泡孔尺寸的泡沫和具有长度大于1cm的泡沫的体积。