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    Porous cellulose body and method for producing same
    4.
    发明授权
    Porous cellulose body and method for producing same 有权
    多孔纤维素体及其制造方法

    公开(公告)号：US09328211B2

    公开(公告)日：2016-05-03

    申请号：US14403541

    申请日：2013-05-15

    申请人： Hokuetsu Kishu Paper Co., Ltd. ,  The University of Tokyo

    发明人： Junji Nemoto ,  Toshihiko Soyama ,  Akira Isogai ,  Tsuguyuki Saito

    IPC分类号： F26B5/06 ,  C08J9/28 ,  C08B15/04 ,  D21H11/20

    CPC分类号： C08J9/28 ,  C08B15/04 ,  C08J2201/0484 ,  C08J2301/02 ,  C08L1/02 ,  D21H11/20 ,  F26B5/06 ,  Y10T428/249965

    摘要： A porous body that contains cellulose nanofibers having very thin fiber diameters and high hydrophilicity, and has a large specific surface area, and to provide a method of producing the porous body simply with low cost. A method of producing a porous cellulose comprises a process of lyophilizing a mixed liquid containing cellulose nanofibers and a dispersion medium, wherein the dispersion medium is a mixed dispersion medium of water and an organic solvent dissolving in water, a concentration of the organic solvent in the mixed dispersion medium is 2 to 40 mass %, and a solid content concentration of the cellulose nanofibers in the mixed liquid is 0.001 to 5 mass %.

    摘要翻译： 一种多孔体，其含有纤维直径非常小，亲水性高，纤维素纳米纤维比表面积大的多孔体，简单地提供低成本地制造多孔体的方法。 多孔性纤维素的制造方法包括将含有纤维素纳米纤维和分散介质的混合液冷冻干燥的方法，其中分散介质是水和溶于水的有机溶剂的混合分散介质，其中有机溶剂的浓度在 混合分散介质为2〜40质量％，混合液中的纤维素纳米纤维的固体成分浓度为0.001〜5质量％。

    POROUS ELECTROLYTIC POLYMER CRYOGELS FOR ENHANCED ELECTRICAL COLLAPSIBILITY
    6.
    发明申请
    POROUS ELECTROLYTIC POLYMER CRYOGELS FOR ENHANCED ELECTRICAL COLLAPSIBILITY 有权
    用于增强电解性的多孔电解聚合物晶体

    公开(公告)号：US20150299415A1

    公开(公告)日：2015-10-22

    申请号：US14418599

    申请日：2013-08-02

    申请人： PRESIDENT AND FELLOWS OF HARVARD COLLEGE

    发明人： Stephen Michael KENNEDY ,  Sidi Ahmed BENCHERIF ,  David J. MOONEY

    IPC分类号： C08J9/28 ,  A61K9/06 ,  A61K9/00

    CPC分类号： C08J9/286 ,  A61K9/0009 ,  A61K9/06 ,  C08F220/06 ,  C08F220/56 ,  C08F2222/1013 ,  C08J9/28 ,  C08J2201/0484 ,  C08J2205/022 ,  C08J2207/10 ,  C08J2333/02 ,  C08J2333/26 ,  C08J2343/00 ,  C08J2347/00

    摘要： The invention provides cryogels whose porosity, pore size, pore connectivity, swelling agent concentration, and/or specific volume undergoes a change from a first value to a second value in response to an electrical stimulus. The cryogels have interconnected macropores which greatly enhance their ability to rapidly undergo volumetric collapse when subjected to moderate electric fields. The cryogels of the invention can be easily integrated into arrays capable of rapid configurational and chromatic optical modulations, and when loaded with drugs, are able to coordinate the delivery profile of multiple drugs. The cryogel can be prepared by polymerizing an aqueous solution of charged monomers and cross-linker monomers at a temperature below the freezing temperature of the solvent.

    摘要翻译： 本发明提供了冷冻凝胶，其孔隙率，孔径，孔连通性，溶胀剂浓度和/或比体积响应于电刺激而经历从第一值到第二值的变化。 冷冻凝胶具有相互连接的大孔，当其受到中等电场的影响时，它们能够迅速地发生体积崩溃的能力。 本发明的冷冻凝胶可以容易地集成到能够进行快速配置和彩色光学调制的阵列中，并且当装载有药物时，能够协调多种药物的递送特征。 可以在低于溶剂冷冻温度的温度下聚合带电荷单体和交联剂单体的水溶液来制备冷冻凝胶。

    FOAM-FORMED COLLAGEN STRAND
    7.
    发明申请
    FOAM-FORMED COLLAGEN STRAND 审中-公开
    泡沫形成的胶原条

    公开(公告)号：US20140329993A1

    公开(公告)日：2014-11-06

    申请号：US14334345

    申请日：2014-07-17

    申请人： Warsaw Orthopedic, Inc.

    发明人： Nels Lauritzen ,  Lawrence a. Shimp ,  Brent S. Mitchell

    IPC分类号： C07K14/78

    CPC分类号： C07K14/78 ,  A61K9/0021 ,  A61K9/122 ,  A61K47/42 ,  A61L17/08 ,  A61L27/24 ,  A61L27/56 ,  C08J9/28 ,  C08J2201/0484 ,  C08J2389/00

    摘要： Foam-formed collagen strands and methods for forming strands involve depositing a dispersed solution of an isolated cleaned, de-fatted, enzymatically-treated (or non-enzyme treated) human-derived collagen product having a preserved amount of its natural constituents into grooves of a grooved plate, and processing the dispersed collagen product to provide a foam-formed collagen strand. Foam-formed collagen strands may be processed into threads having a matrix of reticulated pores to conduct biological materials in and through the strand, the collagen of the collagen strand comprising isolated, enzymatically-treated human derived collagen having a preserved amount of its natural collagen constituents.

    摘要翻译： 泡沫形成的胶原链和用于形成链的方法包括将具有保留量的其天然成分的分离的清除，脱脂，酶处理（或非酶处理）的人源胶原产品的分散溶液沉积在 开槽板，并处理分散的胶原产品以提供泡沫形成的胶原链。 泡沫形成的胶原链可以被加工成具有网状孔基质的丝线，以在该链中进行生物材料，该胶原链的胶原包含分离的，经酶处理的人源胶原，其具有保留量的其天然胶原成分 。