公开(公告)号：US20130090257A1

公开(公告)日：2013-04-11

申请号：US13704070

申请日：2011-06-21

申请人： Nilanjana Banerjee ,  Nevenka Dimitrova ,  Robert Lucito

发明人： Nilanjana Banerjee ,  Nevenka Dimitrova ,  Robert Lucito

IPC分类号： G06F19/18 ,  C12Q1/68

CPC分类号： G16B20/00 ,  C12Q1/6809 ,  G16B5/00 ,  G16B25/00 ,  G16B40/00

摘要： A method for assigning ranking scores to pathways in a set of pathways for classifying patients is disclosed. The method comprises the steps of comparing biomolecular datasets from different groups of patients and performing an analysis in order to assign ranking scores to pathways in a set of pathways. Furthermore, a method for using cancer pathway evaluation to support clinical decision making is disclosed. This assessment is further used for stratifying ovarian cancer patients based on chemosensitivity to platinum based drugs, the standard chemotherapy. We present the method for evaluation and ranking of the most relevant pathways responsible for platinum sensitivity. Clinical decision support software system should be able to then visualize this information for a clinician, contextualize it within a patient data set and help make a final decision on the potential responsiveness.

摘要翻译： 公开了一种用于将排序评分分配给用于分类患者的一组途径中的途径的方法。 该方法包括比较来自不同组患者的生物分子数据集并执行分析以便将一系列途径中的路径分配评级的步骤。 此外，公开了一种使用癌症途径评估来支持临床决策的方法。 该评估进一步用于基于对铂类药物（标准化学疗法）的化学敏感性对卵巢癌患者进行分层。 我们介绍了负责铂敏感性的最相关途径的评估和排名方法。 临床决策支持软件系统应该能够为临床医生可视化这些信息，并在病人数据集内进行语境化，并帮助对潜在的反应能力做出最终决定。

公开(公告)号：US20120016826A1

公开(公告)日：2012-01-19

申请号：US13143420

申请日：2009-12-23

申请人： Narayan Behera ,  Shruti Sinha ,  Rakesh Gupta ,  Ann Geoncy ,  Nevenka Dimitrova

发明人： Narayan Behera ,  Shruti Sinha ,  Rakesh Gupta ,  Ann Geoncy ,  Nevenka Dimitrova

IPC分类号： G06N3/12

CPC分类号： G06F19/24 ,  G06F19/18 ,  G06F19/20

摘要： The invention relates to selecting a set of candidate genes from a pool of genes. The method comprising receiving a set of gene data; arranging the set of gene data into a set of clusters with similar profiles by use of a clustering algorithm; and inputting the set of clusters into a genetic algorithm to select a set of candidate genes from the set of clusters. The method thus relates to hybrid between selection by clustering computation and selection by evolutionary computation. This hybrid is also referred to as an evolutionary clustering algorithm (ECA).

摘要翻译： 本发明涉及从一组基因中选择一组候选基因。 该方法包括接收一组基因数据; 通过使用聚类算法将该组基因数据排列成具有相似特征的集合; 以及将所述集合集合输入到遗传算法中以从所述集合集合中选择一组候选基因。 因此，该方法涉及通过聚类计算和通过进化计算进行选择的选择之间的混合。 该混合也称为进化聚类算法（ECA）。

公开(公告)号：US20110077964A1

公开(公告)日：2011-03-31

申请号：US12992169

申请日：2009-05-06

申请人： Angel J. Janevski ,  Nevenka Dimitrova ,  Sitharthan Kamalakaran ,  Yasser Alsafadi ,  Nilanjana Banerjee ,  Anca Ioana Daniela Bacur ,  Jasper Van Leeuwen ,  Vinay Varadan

发明人： Angel J. Janevski ,  Nevenka Dimitrova ,  Sitharthan Kamalakaran ,  Yasser Alsafadi ,  Nilanjana Banerjee ,  Anca Ioana Daniela Bacur ,  Jasper Van Leeuwen ,  Vinay Varadan

IPC分类号： G06Q50/00

CPC分类号： G16H50/70 ,  G06F19/00 ,  G06Q50/22

摘要： The present invention relates to effective diagnosis of patients and assisting clinicians in treatment planning. In particular, invention provides a medical analysis system that enables refinement of molecular classification. The system provides a molecular profiling solution that will allow improved diagnosis, prognosis, response prediction to provide the right chemotherapy, and follow-up to monitor for cancer recurrence.

摘要翻译： 本发明涉及患者的有效诊断，并协助临床医师进行治疗计划。 特别地，本发明提供了能够细化分子分类的医学分析系统。 该系统提供了一个分子谱分析解决方案，可以改进诊断，预后，反应预测，提供正确的化学疗法和随访监测癌症复发。

公开(公告)号：US20110069898A1

公开(公告)日：2011-03-24

申请号：US12992106

申请日：2009-05-11

申请人： Harsh Dhand ,  Nevenka Dimitrova ,  Hansraj Mishra

发明人： Harsh Dhand ,  Nevenka Dimitrova ,  Hansraj Mishra

IPC分类号： G06K9/36

CPC分类号： G06T9/00 ,  H03M7/30

摘要： A method for compression and/or decompression of bio-medical images such as DNA sequencing images is provided. The method comprises regeneration of a complete image using multiple distribution functions generated on the fly. The compression ratio achieved is in the order of 10 to 20 times, and is near lossless with respect to the clinically relevant information; which makes it well suited for these DNA sequencing images.

摘要翻译： 提供了用于生物医学图像的压缩和/或解压缩的方法，例如DNA测序图像。 该方法包括使用在飞行中产生的多个分布函数来再现完整图像。 实现的压缩比约为10〜20倍，临床相关信息接近无损; 这使得它非常适合这些DNA测序图像。

公开(公告)号：US07734144B2

公开(公告)日：2010-06-08

申请号：US10284219

申请日：2002-10-30

申请人： Nevenka Dimitrova ,  Radu S. Jasinschi

发明人： Nevenka Dimitrova ,  Radu S. Jasinschi

IPC分类号： H04N5/93 ,  G11B27/00 ,  H04N5/91 ,  H04N5/00 ,  H04N5/14

CPC分类号： H04N5/23264 ,  G11B27/031 ,  G11B27/28 ,  G11B2220/216 ,  G11B2220/2545 ,  G11B2220/2562 ,  G11B2220/90 ,  H04N5/145 ,  H04N5/147 ,  H04N5/23248 ,  H04N5/23254 ,  H04N5/262

摘要： A method and apparatus for editing a source video that has already been taken to stabilize images in the video. To eliminate jerky motion from a video, changes in shots are first detected. Then, any jerkiness within the video of that shot is classified and the video is segmented further into smaller segments based on this classification. The jerkiness within the selected segments is removed. The corrected shot, comprising a plurality of frames, is then added to the preceding shot until all shots of the video have been appropriately corrected for jerkiness. To help the user identify the shots being edited, keyframes or snapshots of the shots are displayed, thereby allowing the user to decide whether processing of the shot is desired and which shots should be incorporated into the final video.

摘要翻译： 用于编辑已经被采取以稳定视频中的图像的源视频的方法和装置。 为了消除视频中的抖动，首先会检测到镜头的变化。 然后，该镜头的视频内的任何动作被分类，并且基于该分类将视频进一步分割成较小的片段。 删除所选段中的动作。 然后，将包括多个帧的校正后的镜头添加到前一个镜头，直到视频的所有镜头已经被适当地校正为抖动。 为了帮助用户识别正在编辑的照片，显示拍摄的关键帧或快照，从而允许用户决定是否期望拍摄的处理以及应该将哪些拍摄结合到最终视频中。

公开(公告)号：US20100106078A1

公开(公告)日：2010-04-29

申请号：US12530243

申请日：2008-03-03

申请人： Nevenka Dimitrova ,  Christopher S. Hall ,  Chien T. Chin

发明人： Nevenka Dimitrova ,  Christopher S. Hall ,  Chien T. Chin

IPC分类号： A61N7/00

CPC分类号： A61B8/481 ,  A61K9/0009 ,  A61K41/0028 ,  A61K47/6925 ,  A61M37/0092

摘要： This invention relates to a method and an apparatus of controlling a release of a material carried by ultrasound sensitive particles, the release being caused by irradiating the ultrasound sensitive particles with an ultrasonic pulse having acoustic properties selected so as to interact with the ultrasound sensitive particles and thus causing the release of the material. The ultrasound sensitive particles comprise sub-groups of ultrasound sensitive particles, the ultrasound sensitive particles within the same sub-group having their respective acoustic property causing each respective sub-group to interact independently with the sound wave.

摘要翻译： 本发明涉及一种控制由超声敏感颗粒携带的材料的释放的方法和装置，该释放是通过用选择的声学性质的超声脉冲照射超声波敏感颗粒而引起的，以便与超声敏感颗粒相互作用， 从而导致材料的释放。 超声敏感颗粒包括超声敏感颗粒的子组，相同子组内的超声敏感颗粒具有各自的声学特性，导致每个相应的子组与声波独立地相互作用。

公开(公告)号：US20090055746A1

公开(公告)日：2009-02-26

申请号：US11814092

申请日：2006-01-17

申请人： Nevenka Dimitrova ,  Mauro Barbieri ,  Lalitha Agnihotri

发明人： Nevenka Dimitrova ,  Mauro Barbieri ,  Lalitha Agnihotri

IPC分类号： G06F3/048

CPC分类号： G06F16/58 ,  G06F16/434 ,  G06F16/51

摘要： The present invention enables combining personal media content and additional content with the purpose of generating a more appealing and engaging experience to the user when being presented the personal media content. The invention therefore relates to a method and a device for generating a multimedia presentation, comprising obtaining a user selection of a first media file (step 202), obtaining a user selection of a media file source (step 208), matching content associated data of the first media file, with content associated data of at least one second media file from the media file source (step 214), generating at least one user inquiry related to the content associated data of at least the first media file (step 216), and creating the multimedia presentation, based on the first media file and the at least one second media file, said multimedia presentation comprising the at least one generated user inquiry (step 218).

摘要翻译： 本发明能够将个人媒体内容和附加内容组合，以便在呈现个人媒体内容时向用户生成更具吸引力和吸引人的体验。 因此，本发明涉及一种用于生成多媒体呈现的方法和装置，包括获得第一媒体文件的用户选择（步骤202），获得媒体文件源的用户选择（步骤208），匹配内容相关联的数据 所述第一媒体文件具有来自媒体文件源的至少一个第二媒体文件的内容关联数据（步骤214），生成与至少第一媒体文件的内容关联数据有关的至少一个用户询问（步骤216） 以及基于所述第一媒体文件和所述至少一个第二媒体文件来创建所述多媒体呈现，所述多媒体呈现包括所述至少一个生成的用户查询（步骤218）。

公开(公告)号：US20090041356A1

公开(公告)日：2009-02-12

申请号：US12281005

申请日：2007-02-27

申请人： Mauro Barbieri ,  Lalitha Agnihotri ,  Nevenka Dimitrova

发明人： Mauro Barbieri ,  Lalitha Agnihotri ,  Nevenka Dimitrova

IPC分类号： G06K9/46

CPC分类号： G06F17/30843 ,  G06K9/00751

摘要： Method and device for providing a summary of a plurality of images, e.g. a video sequence. The method includes dividing the video sequence into a plurality of segments. The segments are analyzed with respect to content and a set of content descriptors are associated to the segments. Preferably, additional textual information about the segments, screenplay etc., is used to determine the content descriptors. A graph representing relations between the segments is constructed indicating relations between segments. Weights are associated to the relations so as to represent a measure of relation, e.g. a logical correlation, between segments. The weights are based on the calculated content descriptors. A relevance measure for a segment is determined based on all weights associated with relations to said segment. Finally, a summary is generated by selecting the most relevant segments. The method can create an automatic summary of a film that preserves all the logical plot of the original but is shorter in duration (e.g. 70% of the original film) while the original playback rate is preserved.

摘要翻译： 用于提供多个图像的概要的方法和装置，例如， 视频序列。 该方法包括将视频序列划分成多个段。 关于内容分析段，并且一组内容描述符与段相关联。 优选地，使用关于段，剧本等的附加文本信息来确定内容描述符。 构建表示段之间的关系的图形，指示段之间的关系。 权重与关系相关联，以便表示关系的度量，例如。 段之间的逻辑关联。 权重基于计算的内容描述符。 基于与与所述段的关系相关联的所有权重来确定段的相关性度量。 最后，通过选择最相关的段来生成摘要。 该方法可以创建电影的自动摘要，其保留原始的所有逻辑图，但是在保持原始回放速率的同时，持续时间更短（例如原始电影的70％）。

公开(公告)号：US07089575B2

公开(公告)日：2006-08-08

申请号：US09945871

申请日：2001-09-04

申请人： Lalitha Agnihotri ,  Nevenka Dimitrova ,  Thomas Francis McGee

发明人： Lalitha Agnihotri ,  Nevenka Dimitrova ,  Thomas Francis McGee

IPC分类号： H04H9/00 ,  H04H7/16 ,  H04H5/91

CPC分类号： H04H60/72 ,  H04H60/48 ,  H04H60/56 ,  H04H60/65

摘要： Advertisers want to deliver their message in a relatively short period of time. This leads to the product name, company name and other identifying features being repeated frequently during a commercial broadcast. Transcript information can be used to detect commercials by detecting frequently occurring words in the commercials. This can also be used to identify an individual commercial from other commercials. Once the individual commercials have been identified, the transcript information corresponding to each commercial can be stored in a database to identify the commercial in subsequent broadcasts, or to provide a search mechanism for searching a particular commercial in the database.

摘要翻译： 广告商希望在相对较短的时间内传递他们的信息。 这导致在商业广播期间频繁地重复的产品名称，公司名称和其他识别特征。 记录信息可以通过检测广告中的频繁出现的单词来用于检测广告。 这也可以用于从其他广告中识别单个商业广告。 一旦确定了各个商业广告，则可以将与每个商业广告相对应的抄本信息存储在数据库中以识别后续广播中的商业广告，或提供搜索数据库中的特定广告的搜索机制。

公开(公告)号：US20060041915A1

公开(公告)日：2006-02-23

申请号：US10539697

申请日：2003-12-10

申请人： Nevenka Dimitrova ,  Roli Wendorf

发明人： Nevenka Dimitrova ,  Roli Wendorf

IPC分类号： H04N7/18

CPC分类号： H04L65/1026 ,  H03J2200/24 ,  H04L12/2803 ,  H04L12/2818 ,  H04L12/282 ,  H04L12/2836 ,  H04L12/66 ,  H04L29/06 ,  H04L29/06027 ,  H04L65/1036 ,  H04L65/80 ,  H04L2012/2849 ,  H04N5/4403 ,  H04N5/44582 ,  H04N7/106 ,  H04N7/163 ,  H04N21/4126 ,  H04N21/43615 ,  H04N21/43637 ,  H04N21/440236 ,  H04N21/440263 ,  H04N21/441 ,  H04N21/4751 ,  H04N21/478 ,  H04N21/482 ,  H04N2005/4407 ,  H04N2005/441 ,  H04N2005/4414 ,  H04N2005/4428 ,  H04N2005/443 ,  H04N2005/4444

摘要： A residential gateway system includes a residential gateway to which a plurality of video and audio signal recording and reproducing devices, video and audio sources, including satellite, cable, Internet, are connected, and including a handheld controller for communicating with and controlling the residential gateway. The handheld controller has a display screen for displaying icons for controlling the residential gateway, and for displaying video signals from the residential gateway. Since the display capabilities of the display screen of the handheld controller are limited, the residential gateway includes a transcoder for transcoding video signals for transmission to the handheld controller such that the transmitted video signals may be displayed in their entirety on the display screen of the handheld controller. By transcoding the video signals prior to transmission, valuable bandwidth of the network channel connecting the handheld controller to the residential gateway is save for the transmission of other information and signals.

摘要翻译： 住宅网关系统包括住宅网关，多个视频和音频信号记录和再现设备，视频和音频源（包括卫星，电缆，因特网）连接到该住宅网关，并且包括用于与住宅网关进行通信和控制的手持式控制器 。 手持控制器具有用于显示用于控制住宅网关的图标的显示屏幕，以及用于显示来自住宅网关的视频信号。 由于手持式控制器的显示屏的显示能力受到限制，所以住宅网关包括用于对视频信号进行代码转换以传输到手持式控制器的代码转换器，使得发送的视频信号可以全部显示在手持设备的显示屏上 控制器。 通过在传输之前对视频信号进行代码转换，节省了将手持控制器连接到住宅网关的网络通道的有价值带宽，用于传输其他信息和信号。