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81.发明申请Energy Storage for Power Factor Correction in Battery Charger for Electric-Powered Vehicles 有权电动车辆电池充电器功率因数校正的能量存储公开(公告)号：US20140306663A1
公开(公告)日：2014-10-16
申请号：US14139059
申请日：2013-12-23
发明人： Khai Doan The Ngo , Hui Wang
IPC分类号： B60L11/18
CPC分类号： B60L11/1803 , B60L11/1812 , B60L2210/14 , B60L2220/54 , B60L2240/526 , B60L2240/527 , B60L2240/529 , H02M1/14 , H02M1/4225 , H02M7/5387 , Y02T10/641 , Y02T10/7005 , Y02T10/7072 , Y02T10/7225 , Y02T90/127 , Y02T90/14
摘要： Switches of a switching circuit used to control operation of an electric motor such as in an electrically powered vehicle connect respective windings of the electric motor as a single phase inductor during battery charging. The inductor can then store inherent low frequency, second order ripple power and return that power to a load presented by a battery during battery charging to deliver substantially constant current. Storage of ripple power in the inductor allows the capacitance value, size, weight and cost of a filter capacitor of a power factor correction circuit providing input power to a battery charger to be reduced by an order of magnitude or more. Direction of current flow through the inductor is periodically reversed to avoid magnetizing the motor.
摘要翻译： 用于控制诸如电动车辆中的电动机的操作的开关电路的开关在电池充电期间将电动机的各个绕组作为单相电感器连接。 然后，电感器可以存储固有的低频二阶纹波功率，并在电池充电期间将电力返回给由电池呈现的负载，以输送基本上恒定的电流。 在电感器中存储纹波功率允许向电池充电器提供输入功率的功率因数校正电路的滤波电容器的电容值，尺寸，重量和成本降低一个数量级以上。 电流流过电感的方向周期性地反转，以避免电机的磁化。
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82.发明申请V+hu 2 +l Power Converter Control with Capacitor Current Ramp Compensation 有权V + hu 2 + l电容转换器控制电容电流斜坡补偿公开(公告)号：US20140292300A1
公开(公告)日：2014-10-02
申请号：US14183841
申请日：2014-02-19
发明人： Yingyi Yan , Pei-Hsin Liu , Fred C. Lee
IPC分类号： H02M3/158
CPC分类号： H02M3/156 , H02M3/157 , H02M2003/1566
摘要： Operation of a switching power converter having an output capacitor having a small equivalent series resistance (ESR) is stabilized and jitter reduced by sensing capacitor current with gain and combining the resulting signal with the output voltage signal to provide a feedback signal to control switching of the power converter. capacitor current can be sensed without interfering with operation of the filter capacitor by providing a branch circuit having a time constant matched to the output or filter capacitor but an arbitrarily high impedance so as to be effectively lossless. The gain provided in the capacitor current signal can be tuned to provide optimally short settling time after load transients; generally within one switching cycle. Matching of time constants and/or tuning of gain can be performed automatically.
摘要翻译： 具有小等效串联电阻（ESR）的输出电容器的开关电源转换器的操作通过用增益感测电容器电流而稳定并且抖动降低，并且将所得到的信号与输出电压信号组合以提供反馈信号以控制 电源转换器 可以通过提供具有与输出或滤波电容器匹配的时间常数但是具有任意高阻抗的分支电路来检测电容器电流而不干扰滤波电容器的操作，以便有效地无损。 可以调整电容电流信号中提供的增益，以便在负载瞬变之后提供最佳的稳定时间; 一般在一个开关周期内。 可以自动执行时间常数和/或增益调谐的匹配。
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83.发明授权Transition metal complexes of amino acids and related ligands and their use as catalysts, anti-microbials, and anti-cancer agents 有权氨基酸和相关配体的过渡金属络合物及其作为催化剂，抗微生物剂和抗癌剂的用途公开(公告)号：US08841281B2
公开(公告)日：2014-09-23
申请号：US13653883
申请日：2012-10-17
发明人： Joseph S. Merola
IPC分类号： A61K31/66 , C07D207/00
CPC分类号： C07F15/0033 , C07F15/0073 , C07F17/02
摘要： The present invention relates to the fields of chemistry and pharmaceuticals. Embodiments of the present invention provide transition metal complexes of amino acids. Transition metal complexes of embodiments of the invention according to Categories I, II, III, and/or IV may be used as antimicrobial, anti-malarial, and anti-cancer agents, as well as catalysts in chemical reactions. Such compounds of the invention are particularly useful for combating multi-drug resistance against a broad range of microbials (such as MRSA and mycobacteria), including gram positive and gram negative bacteria, as well as can be used as anti-cancer agents against bladder cancer, breast cancer, colon cancer, rectal cancer, endometrial cancer, kidney cancer, leukemia, lung cancer, melanoma, non-Hodgkin's lymphoma, pancreatic cancer, prostate cancer, and thyroid cancer, to name a few.
摘要翻译： 本发明涉及化学和药物领域。 本发明的实施方案提供氨基酸的过渡金属络合物。 根据类别I，II，III和/或IV的本发明的实施方案的过渡金属络合物可以用作抗微生物剂，抗疟剂和抗癌剂以及化学反应中的催化剂。 本发明的这些化合物特别可用于抵抗广泛范围的微生物（如MRSA和分枝杆菌）（包括革兰氏阳性菌和革兰氏阴性细菌）的多药耐药性，并且可用作抗膀胱癌的抗癌剂 ，乳腺癌，结肠癌，直肠癌，子宫内膜癌，肾癌，白血病，肺癌，黑素瘤，非霍奇金淋巴瘤，胰腺癌，前列腺癌和甲状腺癌。
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84.发明申请公开(公告)号：US20140039489A1
公开(公告)日：2014-02-06
申请号：US14017210
申请日：2013-09-03
CPC分类号： A61B18/1206 , A61B18/14 , A61B18/1477 , A61B2018/00446 , A61B2018/00577 , A61B2018/00613 , A61B2034/104 , A61N1/05 , A61N1/327 , C12N13/00
摘要： A method is provided for ablating brain tissue of a living mammal comprising: placing first and second electrodes in a brain of the living mammal; applying a plurality of electrical pulses through the first and second placed electrodes which are predetermined to: cause irreversible electroporation (IRE) of brain tissue of the mammal within a target ablation zone; and cause a temporary disruption of a blood brain barrier (BBB) within a surrounding zone that surrounds the target ablation zone to allow material in a blood vessel to be transferred to the surrounding zone through the temporarily disrupted BBB. Such methods are useful for delivering large molecule material within a blood vessel of the brain across the BBB, where the large molecule is otherwise blocked by the BBB from passing through the blood vessel into the brain.
摘要翻译： 提供了一种用于消融活体哺乳动物的脑组织的方法，包括：将第一和第二电极放置在活的哺乳动物的脑中; 施加多个电脉冲通过所述第一和第二放置的电极，所述电脉冲预定为：引起所述哺乳动物在靶消融区内的脑组织的不可逆电穿孔（IRE）; 并引起围绕目标消融区域的周围区域内的血脑屏障（BBB）的暂时中断，以允许血管中的物质通过暂时中断的BBB转移到周围区域。 这种方法可用于在大脑血管内的BBB上输送大分子物质，其中大分子另外被BBB阻断以通过血管进入大脑。
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85.发明申请公开(公告)号：US20140032148A1
公开(公告)日：2014-01-30
申请号：US13954014
申请日：2013-07-30
发明人： Jacob Verhulst , Mohamed Belkhayat , Zhiyu Shen , Marko Jaksic , Paolo Mattavelli , Dushan Boroyevich
IPC分类号： G01R27/16
摘要： A method for impedance measurement in a three-phase AC system is provided. The method includes injecting a shunt perturbation signal into the three-phase AC system and collecting a response to the shunt perturbation signal, and injecting a series perturbation signal into the three-phase AC system and collecting a response to the series perturbation signal. The response to the shunt perturbation signal and the response to the series perturbation signal are then transferred from abc coordinate to dq coordinates. At least one impedance of the three-phase AC system is calculated based on the response to the shunt perturbation signal and the response to the series perturbation signal.
摘要翻译： 提供了一种三相交流系统中的阻抗测量方法。 该方法包括将分流扰动信号注入到三相交流系统中并收集对分流扰动信号的响应，并将一系列扰动信号注入到三相交流系统中并收集对串联扰动信号的响应。 对分流扰动信号的响应和对串联扰动信号的响应然后从abc坐标传递到dq坐标。 基于对分流扰动信号的响应和对串联扰动信号的响应，计算三相AC系统的至少一个阻抗。
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86.发明申请公开(公告)号：US20130178614A1
公开(公告)日：2013-07-11
申请号：US13661028
申请日：2012-10-25
发明人： Kevin Edgar , Daiqiang Xu , Xueyan Zheng
摘要： Embodiments of the invention provide regioselectively substituted carbohydrate and polysaccharide derivatives, such as cellulose esters, and methods for preparing them. Particular methods of the invention include deacylation of esters using tetrabutylammonium fluoride to obtain selective substitution at desired hydroxyl position(s) of the ester. Preferred is deacylation of an ester, which shows selectivity for removal of acyl groups from the ester of the secondary alcohols at C-2 and C-3, and which affords cellulose-6-O-esters with high regioselectivity by a simple one-step process employing no protective groups. Inventive regioselectively substituted cellulose esters can be prepared by such methods to obtain esters with the following anhydroglucose repeating units: wherein R1, R2, and R3 are each independently chosen from a hydrogen atom, and, whether substituted or unsubstituted, branched or unbranched, an alkanoyl group, an aroyl group, and a heteroaroyl group. In embodiments, the alkanoyl, aroyl and heteroaroyl groups can comprise from 1-20 carbon atoms.
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87.发明申请Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof 有权嵌合感染性DNA克隆，嵌合型猪圆环病毒及其用途公开(公告)号：US20030170270A1
公开(公告)日：2003-09-11
申请号：US10314512
申请日：2002-12-09
IPC分类号： C12P021/06 , A61K048/00 , A01N063/00 , A61K039/12 , C12N015/00 , C12N015/09 , C12N015/63 , C12N015/70 , C12N015/74
CPC分类号： C07K14/005 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , C12N7/00 , C12N2750/10022 , C12N2750/10034 , C12N2750/10061
摘要： The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome (PMWS) caused by PCV2. The new chimeric infectious DNA clone and its derived, avirulent chimeric virus are constructed from the nonpathogenic PCV1 in which the immunogenic ORF gene of the pathogenic PCV2 replaces a gene of the nonpathogenic PCV1, preferably in the same position. The chimeric virus advantageously retains the nonpathogenic phenotype of PCV1 but elicits specific immune responses against the pathogenic PCV2. The invention further embraces the immunogenic polypeptide expression products.
摘要翻译： 本发明涉及感染性DNA克隆，猪圆环病毒感染性嵌合DNA克隆（PCV），疫苗和保护猪免受病毒感染或PCV2引起的断奶后多系统消耗综合征（PMWS）的方法。 新的嵌合感染性DNA克隆及其衍生的无毒性嵌合病毒由非致病性PCV1构建，其中病原性PCV2的免疫原性ORF基因替代非致病性PCV1的基因，优选在相同的位置。 嵌合病毒有利地保留了PCV1的非病原性表型，但引发针对致病性PCV2的特异性免疫应答。 本发明还包括免疫原性多肽表达产物。
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公开(公告)号：US20020058779A1
公开(公告)日：2002-05-16
申请号：US09887979
申请日：2001-06-22
IPC分类号： C08G079/02
CPC分类号： C08G79/04
摘要： High refractive index, melt processable polyphosphonates and methods for preparing the same are provided. These polymers are particularly useful for optical and ophthalmic parts, such as lenses. A method of preparing optical and ophthalmic lenses by injection molding the polymers of the present invention into the form of the optical or ophthalmic lenses is also provided.
摘要翻译： 提供高折射率，可熔融加工的聚膦酸盐及其制备方法。 这些聚合物特别适用于光学和眼科部件，例如透镜。 还提供了通过将本发明的聚合物注射成光学或眼科镜片的形式来制备光学和眼科镜片的方法。
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公开(公告)号：US20230122794A1
公开(公告)日：2023-04-20
申请号：US17841954
申请日：2022-06-16
发明人： Rimon Gadelrab , Fred C. Lee
摘要： Three-phase interleaved resonant converters with integrated magnetics are described. In various examples, transformers are integrated into a transformer core of a converter. A primary side circuit includes a set of circuit segments corresponding to phases of the three-phase interleaved converter. Each of the circuit segments include an integrated winding component that provides a transformer primary winding and a resonant inductor connected in series.
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公开(公告)号：US20220410646A1
公开(公告)日：2022-12-29
申请号：US17809081
申请日：2022-06-27
IPC分类号： B60G13/10 , B60G17/015 , B60G17/08
摘要： In one or more embodiments, a double damper is disclosed that may be used in an automotive suspension system. In one embodiment, a double damper includes a first damper having a first piston rod, a first gas chamber, a first compression chamber, and a first rebound chamber. The double damper further includes a second damper having a second piston rod, a second gas chamber, a second compression chamber, and a second rebound chamber. The first damper and the second damper are connected via a sleeve from which the first piston rod and the second piston rod extend at opposite ends.
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