公开(公告)号：US20070220078A1

公开(公告)日：2007-09-20

申请号：US11755128

申请日：2007-05-30

Applicant: David Clark ,  Michael Cowlishaw

Inventor： David Clark ,  Michael Cowlishaw

IPC: G06F7/38

CPC classification number: G06F7/535 ,  G06F2207/5353

Abstract: A data processing apparatus uses numeric processing. A corrective mechanism enables a method for performing accurate integer divisions to be derived from an approximate division method which does not, of itself, always produce an accurate result but for which the range of errors is known. By applying the corrective mechanism to a suitable approximate division method, a numeric processing mechanism performs the integer division operation efficiently. An approximate division method that uses rapid operations for fast integer division, and thus has a small possible range of errors, is used to enable the correction method to be completed rapidly.

Abstract translation: 数据处理装置使用数字处理。 校正机制使得能够从近似分割方法导出精确的整数除法的方法，该近似除法本身不总是产生准确的结果，而是误差范围是已知的。 通过将校正机制应用于合适的近似分割方法，数字处理机构有效地执行整数除法运算。 一种使用快速运算进行快速整数除法，因此具有较小可能误差范围的近似除法，用于使校正方法快速完成。

公开(公告)号：US20070203179A1

公开(公告)日：2007-08-30

申请号：US10596998

申请日：2005-01-10

Applicant: Robin Clark ,  Nicholas Ray ,  Paul Blaney ,  Christopher Hurley ,  Hazel Hunt ,  David Clark ,  Karen Williams

Inventor： Robin Clark ,  Nicholas Ray ,  Paul Blaney ,  Christopher Hurley ,  Hazel Hunt ,  David Clark ,  Karen Williams

IPC: A61K31/47 ,  C07D217/04 ,  C07D217/08

CPC classification number: C07D217/04 ,  C07D217/02 ,  C07D217/06 ,  C07D217/08 ,  C07D401/10 ,  C07D401/12 ,  C07D405/06 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D491/10 ,  C07D513/04 ,  C07D513/06

Abstract: The present invention provides a novel class of azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.

Abstract translation: 本发明提供了一类新颖的氮杂环丁烷化合物和使用该化合物作为糖皮质激素受体调节剂的方法。

公开(公告)号：US20070197443A1

公开(公告)日：2007-08-23

申请号：US11736632

申请日：2007-04-18

Applicant: Reginald Gorczynski ,  David Clark

Inventor： Reginald Gorczynski ,  David Clark

IPC: A61K48/00 ,  A61K38/17

CPC classification number: C07K14/70503 ,  A61K38/00 ,  A61K48/00 ,  A61K2039/505 ,  C07K16/2803 ,  C07K2319/00 ,  C07K2319/30

Abstract: Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of a CD200 protein or a nucleic acid encoding a CD200 protein. The methods are useful in preventing graft rejection, fetal loss, autoimmune disease, and allergies. Methods and compositions for preventing immune suppression are also disclosed. The methods involve administering an effective amount of an agent that inhibits CD200. Such methods are useful in treating cancer.

Abstract translation: 公开了诱导免疫抑制的方法和组合物。 所述方法包括施用有效量的CD200蛋白或编码CD200蛋白的核酸。 该方法可用于预防移植物排斥，胎儿丧失，自身免疫性疾病和过敏。 还公开了用于预防免疫抑制的方法和组合物。 所述方法包括施用有效量的抑制CD200的药剂。 这些方法可用于治疗癌症。

公开(公告)号：US20070135464A1

公开(公告)日：2007-06-14

申请号：US11650268

申请日：2007-01-05

Applicant: Michelle Browner ,  David Clark ,  Timothy Cushing ,  Xiaolin Hao ,  Ronald Hawley ,  Xiao He ,  Juan Jaen ,  Sharada Labadie ,  Marie-Louise Smith ,  Francisco Talamas ,  Nigel Walker ,  Marc Labelle

Inventor： Michelle Browner ,  David Clark ,  Timothy Cushing ,  Xiaolin Hao ,  Ronald Hawley ,  Xiao He ,  Juan Jaen ,  Sharada Labadie ,  Marie-Louise Smith ,  Francisco Talamas ,  Nigel Walker ,  Marc Labelle

IPC: A61K31/519 ,  A61K31/4709 ,  C07D403/04

CPC classification number: C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D405/14 ,  C07D417/04 ,  C07D471/04

Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic and cell proliferative conditions or diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism and cell proliferation. The subject compounds contain fused carbocyclic or heterocyclic rings.

公开(公告)号：US20070123575A1

公开(公告)日：2007-05-31

申请号：US11615024

申请日：2006-12-22

Applicant: Alexander Oxford ,  Richard Davis ,  Robert Coleman ,  Kenneth Clark ,  David Clark ,  Neil Harris ,  Garry Fenton ,  George Hynd ,  Keith Stuttle ,  Jonathan Sutton ,  Christopher Newton

Inventor： Alexander Oxford ,  Richard Davis ,  Robert Coleman ,  Kenneth Clark ,  David Clark ,  Neil Harris ,  Garry Fenton ,  George Hynd ,  Keith Stuttle ,  Jonathan Sutton ,  Christopher Newton

IPC: A61K31/41 ,  A61K31/34 ,  C07D405/02

CPC classification number: C07D307/54 ,  A61K31/34 ,  A61K31/341 ,  A61K31/4155 ,  A61K31/443 ,  C07D307/64 ,  C07D307/68 ,  C07D405/12 ,  C07D407/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14

Abstract: Compounds of formula (I): wherein: R2 is H or an optionally substituted C1-4 alkyl group; Y is either —(CH2)n—X—, where n is 1 or 2 and X is O, S, S(═O), S(═O)2, or NRN1, where RN1 is selected from H or optionally substituted C1-4 alkyl, or Y is —C(═O)NRN2—, where RN2 is selected from H, and optionally substituted C1-7 alkyl or C5-20 aryl; R3 is an optionally substituted C6 aryl group linked to a further optionally substituted C6 aryl group, wherein if both C6 aryl groups are benzene rings, there may be an oxygen bridge between the two rings, bound adjacent the link on both rings; A is a single bond or a C1-3 alkylene group; and R5 is either: (i) carboxy; (ii) a group of formula (II): ; or (iii) a group of formula (III): wherein R is optionally substituted C1-7 alkyl, C5-20 aryl or NRN3RN4, where RN3 and RN4 are independently selected from optionally substituted C1-4 alkyl; (iv) tetrazol-5-yl.

Abstract translation: 式（I）的化合物：其中：R 2是H或任选取代的C 1-4烷基; Y是 - （CH 2）n -X-，其中n是1或2，X是O，S，S（-O），S（-O ）N 2，或NR 11，其中R 0,1选自H或任选取代的C 1-4烷基 ，或Y是-C（-O）NR N2 - ，其中R N2选自H和任选取代的C 1-7 - 烷基或C 5-20-20芳基; R 3是与另外任选取代的C 6 -C 6芳基连接的任选取代的C 6-14芳基，其中如果两个C 6 芳基是苯环，两个环之间可能有一个氧桥，与两个环上的连接相邻; A是单键或C 1-3-3亚烷基; 和R 5是：（i）羧基; （ii）式（II）的组： 或（iii）式（III）的基团：其中R是任选取代的C 1-7烷基，C 5-20-20芳基或NR N 3， 其中R“N 3”和“R”N 4“独立地选自任选取代的C 1-4烷基 ; （ⅳ）四唑-5-基。

公开(公告)号：US20070084942A1

公开(公告)日：2007-04-19

申请号：US10579123

申请日：2004-11-15

Applicant: Nigel Moore ,  Heather Allderidge ,  Frank Ferdnandi ,  Christopher Spenceley ,  Adrian Richardson ,  Wayne Aldridge ,  David Clark ,  Alan Mccarthy-Wyper

Inventor： Nigel Moore ,  Heather Allderidge ,  Frank Ferdnandi ,  Christopher Spenceley ,  Adrian Richardson ,  Wayne Aldridge ,  David Clark ,  Alan Mccarthy-Wyper

IPC: F24D3/08

CPC classification number: F24H1/00 ,  F02G1/043 ,  F02G5/00 ,  F02G2254/10 ,  F23N5/102 ,  F23N2025/12 ,  F23N2025/16 ,  F23N2037/02 ,  F23N2041/06 ,  F24D19/1009 ,  F24H2240/04 ,  Y02E20/14 ,  Y02T10/166

Abstract: This invention relates to domestic heat and power systems that allow efficient methods of operating a domestic combined heat and power (dchp) unit and to energy-efficient methods of scheduling domestic appliance operation within a household having a dchp unit. Dchp units provide heating and hot water for the home and also generate electricity for use in the home. A domestic heat and power system is provided that comprises a dchp unit, a dchp unit controller, a programmer module and an energy scheduler linked to allow communication therebetween, wherein the programmer module receives data input and generates a heating and/or hot water schedule therefrom, the dchp unit controller determines operating times of the dchp unit in accordance with the schedule and provides the operating times to the energy scheduler that then operates the domestic appliance during operating times.

Abstract translation: 本发明涉及家庭热电系统，其允许运行国内热电联产单元的有效方法以及在具有dchp单元的家庭内调节家用电器操作的节能方法。 Dchp单位为家庭提供加热和热水，并在家中发电。 提供了一种家用热电系统，其包括dchp单元，dchp单元控制器，编程器模块和链接以允许其间通信的能量调度器，其中编程器模块接收数据输入并且从其产生加热和/或热水调度表 ，dchp单元控制器根据时间表确定dchp单元的操作时间，并将操作时间提供给在操作时间期间操作家用电器的能量调度器。

公开(公告)号：US20070073536A1

公开(公告)日：2007-03-29

申请号：US11534501

申请日：2006-09-22

Applicant: David Clark ,  Andrew Weber

Inventor： David Clark ,  Andrew Weber

IPC: G10L15/00

CPC classification number: H04M1/271 ,  G10L15/26 ,  H04M2250/74

Abstract: Methods and systems to enable touch-free call origination using a communication device equipped with a microphone. The method comprises processing a first microphone signal at the device in an attempt to detect a spoken activation command potentially contained therein. Responsive to detection of a spoken activation command in the first microphone signal, the method continues by establishing a communication path between the device and a network entity to convey to the network entity a second microphone signal. Finally, the method comprises processing the second microphone signal at the network entity in an attempt to detect a call origination command potentially contained therein; and, responsive to detection of a call origination command in the second microphone signal, attempting establishment of a call in accordance with the detected call origination command. Thus, a call can be established without tactile interaction with the device and, moreover, with minimal computational load on the device.

Abstract translation: 使用配备有麦克风的通信设备实现无触摸呼叫发起的方法和系统。 该方法包括在设备处处理第一麦克风信号以试图检测潜在地包含在其中的语音激活命令。 响应于在第一麦克风信号中检测到语音激活命令，该方法通过在设备和网络实体之间建立通信路径来继续向网络实体传送第二麦克风信号。 最后，该方法包括在网络实体处理第二麦克风信号，以试图检测潜在地包含在其中的呼叫发起命令; 并且响应于在所述第二麦克风信号中检测到呼叫发起命令，根据检测到的呼叫发起命令尝试建立呼叫。 因此，可以建立呼叫而没有与设备的触觉交互，此外，在设备上具有最小的计算负载。

公开(公告)号：US20070027253A1

公开(公告)日：2007-02-01

申请号：US11541860

申请日：2006-10-02

Applicant: Thomas Jones ,  David Clark ,  Lirio Quintero ,  Bruce Ewen

Inventor： Thomas Jones ,  David Clark ,  Lirio Quintero ,  Bruce Ewen

IPC: C08L77/00

CPC classification number: C09K8/52 ,  C09K8/36 ,  C09K2208/18 ,  Y10S507/91 ,  Y10S507/929

Abstract: Single phase microemulsions improve the removal of filter cakes formed during drilling with invert emulsions. The single phase microemulsion removes oil and solids from the deposited filter cake. Optionally, an acid capable of solubilizing the filter cake bridging particles may also be used with the microemulsion. In one non-limiting embodiment the acid may be a polyamino carboxylic acid. Skin damage removal from internal and external filter cake deposition can be reduced.

Abstract translation: 单相微乳液可改善用倒置乳液在钻孔过程中形成的滤饼的去除。 单相微乳液从沉积的滤饼中除去油和固体。 任选地，也可以与微乳液一起使用能够增溶滤饼桥接颗粒的酸。 在一个非限制性实施方案中，酸可以是聚氨基羧酸。 可以减少从内部和外部滤饼沉积物中去除皮肤损伤。

公开(公告)号：US20060153347A1

公开(公告)日：2006-07-13

申请号：US11289580

申请日：2005-11-30

Applicant: David Clark ,  Gregory Lam ,  Sean Murray ,  David Johnston

Inventor： David Clark ,  Gregory Lam ,  Sean Murray ,  David Johnston

IPC: H04M11/00

CPC classification number: H04M3/5307 ,  H04L51/24 ,  H04L51/36 ,  H04M7/0027 ,  H04M2201/38

Abstract: A method suitable for execution by a voice mail system for handling a call placed by a caller. The method comprises providing the caller with an opportunity to submit a voice segment and providing the caller with an opportunity to submit an auxiliary electronic message, such as text or files. A composite message comprising the voice segment and the auxiliary electronic message is stored in a database. The auxiliary electronic message is released to its intended recipient upon subsequent interaction between the intended recipient and the voice mail system. The ability of the caller to submit text or files increases the accuracy and flexibility with which certain types of information can be conveyed to the intended recipient. At the same time, the ability of the intended recipient to access text or files associated with individual messages allows the intended recipient to better manage missed calls when eventually accessing his or her mailbox.

Abstract translation: 一种适用于语音邮件系统执行以处理由呼叫者发出的呼叫的方法。 该方法包括向呼叫者提供提交语音段并提供呼叫者提供诸如文本或文件的辅助电子消息的机会的机会。 包括语音段和辅助电子消息的复合消息被存储在数据库中。 辅助电子消息在预期收件人和语音邮件系统之间的后续交互中被释放到其预期的接收者。 呼叫者提交文本或文件的能力增加了将某些类型的信息传达给预期收件人的准确性和灵活性。 同时，预期收件人访问与单个消息相关联的文本或文件的能力允许预期收件人在最终访问他或她的邮箱时更好地管理未接来电。

公开(公告)号：US20060130143A1

公开(公告)日：2006-06-15

申请号：US11011238

申请日：2004-12-14

Applicant: Theodore Shrader ,  David Clark ,  Mary Ferguson ,  Julie Gilbreath

Inventor： Theodore Shrader ,  David Clark ,  Mary Ferguson ,  Julie Gilbreath

IPC: G06F11/00 ,  G06F11/22 ,  G06F11/30 ,  G06F11/32 ,  G06F11/34 ,  G06F11/36 ,  G06F12/14 ,  G06F12/16 ,  H04L9/32 ,  G06F15/18 ,  G08B23/00

CPC classification number: G06F16/9535

Abstract: Provided are methods and systems that facilitate automated networked distribution of information. In particular, a plurality of information worms are evaluated, one or more of the information worms are selected based on the evaluation, and the selected information worms are incorporated into one or more information channels suitable for automated distribution across a network.

Abstract translation: 提供了便于自动化网络分发信息的方法和系统。 特别地，评估多个信息蠕虫，基于评估来选择一个或多个信息蠕虫，并且将所选择的信息蠕虫并入适合于通过网络自动分发的一个或多个信息信道。