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81.发明授权公开(公告)号：US06436084B1
公开(公告)日：2002-08-20
申请号：US09161044
申请日：1998-09-25
IPC分类号： A61M3100
CPC分类号： A61M39/0208 , A61M25/0017 , A61M31/00 , A61M39/16 , A61M2039/0226
摘要： Implantable ports and other devices are disinfected by the injection of an anti-microbial agent into a region in the device or in a tissue pocket surrounding the device. In a first embodiment, the anti-microbial agent is injected through an aperture in the device to flush internal regions of the device before infusing the tissue pocket and flushing outwardly through a tissue tract leading to the device. In other embodiments, the anti-microbial agent is injected directly to a target site on the exterior of the device. Implantable devices may include special, usually hardened, target regions for receiving the sharpened end of a needle used to inject the anti-microbial agent. Kits will include devices, syringes, access devices, and instructions for disinfection according to the methods of the present invention.
摘要翻译： 可植入端口和其它装置通过将抗微生物剂注入设备中的区域或围绕设备的组织袋中来消毒。 在第一个实施方案中，抗微生物剂通过装置中的孔注入，以在灌注组织袋之前冲洗装置的内部区域并向外冲洗穿过通向该装置的组织通道。 在其它实施方案中，将抗微生物剂直接注射到装置外部的靶位点。 可植入装置可以包括用于接收用于注射抗微生物剂的针的尖端的特殊的，通常硬化的靶区域。 试剂盒将包括根据本发明的方法的装置，注射器，进入装置和消毒说明书。
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82.发明授权Systems and methods for removing retained fluids and infusing therapeutic fluids 有权用于清除残留流体和注入治疗液的系统和方法
公开(公告)号：US6132415A
公开(公告)日：2000-10-17
申请号：US248156
申请日：1999-02-09
申请人： Charles David Finch , Jeffrey H. Burbank , James M. Brugger , John E. Moran , John H. Wang , Hendrick K. Kuiper
发明人： Charles David Finch , Jeffrey H. Burbank , James M. Brugger , John E. Moran , John H. Wang , Hendrick K. Kuiper
CPC分类号： A61M1/0062 , A61M1/0068 , A61M39/0208
摘要： Systems for draining retained body fluids comprise an implantable port in an access tube. Usually, a drainage cannula for connecting the implantable port to a site of fluid retention is also provided. The implantable port and drainage cannula are implanted subcutaneously with one end of the cannula within the site of fluid retention and the port located remotely from such site. Drainage may then be effected by percutaneously introducing the access tube to the port and optionally applying a vacuum. Kits comprise the implantable port together with instructions for implanting the port as described above. Kits also comprise an access tube with instructions for use for accessing an implanted port as described above.
摘要翻译： 用于排出保留体液的系统包括进入管中的可植入口。 通常，还提供了用于将可植入端口连接到流体保持部位的排水套管。 可植入端口和排液套管皮下植入插管的一端，并位于远离该位置的流体保持部位。 然后可以通过将入口管经皮引入端口并任选地施加真空来实现排水。 套件包括可植入端口以及如上所述的用于植入端口的指令。 如上所述，套件还包括具有用于访问植入端口的指令的入口管。
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公开(公告)号：US6053901A
公开(公告)日：2000-04-25
申请号：US724948
申请日：1996-10-02
CPC分类号： A61F2/064 , A61M39/0208 , A61M2039/0211
摘要： A catheter with valve for implantation in a vascular structure of a living being. The catheter is in the general shape of a "T" with the top of the "T" implanted within the lumen of a vascular structure, and the leg of the "T" extending out of the vascular structure through an incision in the vascular structure. The lumen of the implanted portion of the catheter completely occupies the lumen of the vascular structure, causing all blood flow through the vascular structure to be directed through the implanted portion of the catheter. A valve is placed in the wall of the implanted portion of the catheter which opens into the lumen of the leg of the "T" of the catheter upon application of sufficient differential pressure between the lumens of the two portions of the catheter. The leg of the "T" is connected to the side wall of the implant portion of the catheter at an angle, such that the axis of the lumen of the leg of the "T" intersects the axis of the lumen of the implanted portion of the catheter at approximately a 45 degree angle.
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公开(公告)号：US5639810A
公开(公告)日：1997-06-17
申请号：US483740
申请日：1995-06-07
IPC分类号： A61L15/00 , A61L29/04 , A61L29/06 , A61L29/14 , A61L31/00 , A61L31/04 , A61L31/06 , A61L31/14 , A61M39/04 , C08K5/00 , C08L21/00 , C08L23/00 , C08L75/00 , C08L75/04 , C08L83/04 , C08K5/24
CPC分类号： A61M39/04 , A61L29/041 , A61L29/042 , A61L29/049 , A61L29/06 , A61L29/14 , A61L31/041 , A61L31/048 , A61L31/049 , A61L31/06 , A61L31/14 , A61M2039/0036 , A61M2039/0063 , A61M2039/0072 , A61M2205/197
摘要： Improved elastomeric materials useful for medical and therapeutic device applications, such as penetrable septa, are described. In one aspect, the materials are deeply cleaned with solvent to significantly lower levels of undesirable organics. In another aspect, internally lubricated elastomer compositions compatible for use in medical and therapeutic device applications are provided. The lubricating fluid is present in the composition from about 0.5% to 50% by weight, and is initially substantially homogeneously dispersed in the elastomer. The fluid can be integrated into the elastomer by a solvent infusion method. In another aspect an internally lubricated thermoplastic septum, having an appropriate hardness for resealability with multiple penetrations, is provided.
摘要翻译： 描述了可用于医疗和治疗装置应用的改进的弹性体材料，例如可穿透的隔垫。 在一个方面，材料用溶剂深度清洁以显着降低不期望的有机物的水平。 在另一方面，提供了兼容于医疗和治疗装置应用中的内部润滑的弹性体组合物。 润滑液在组合物中的含量为约0.5％至50％，最初基本均匀地分散在弹性体中。 流体可以通过溶剂注入法整合到弹性体中。 在另一方面，提供一种内部润滑的热塑性隔膜，其具有适合于具有多次穿透的可再密封性的硬度。
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公开(公告)号：US5322516A
公开(公告)日：1994-06-21
申请号：US65118
申请日：1993-05-20
申请人： James M. Brugger
发明人： James M. Brugger
CPC分类号： A61M39/04
摘要： A medical system for transferring fluids (e.g. blood) to or from patients which includes a needle having a proximal end, a distal end attached to a syringe (or other comparable fluid transfer device), a medial section, and an internal passageway. The medial section is elliptical in cross-section with dual arcuate side walls. The proximal end is blunt and rounded. Also included is an access site having a conduit with a resilient tubular port extending outwardly therefrom. The port includes a bore therethrough. The port and the bore are both elliptical in cross-section. A resilient compression member having an elliptical opening therein is positioned on the port to exert pressure thereon and close the bore. In use, the needle is urged into the bore, temporarily deforming the compression member. After removing or delivering fluids using the syringe (or other device), the needle is withdrawn from the bore which is self-sealing by the compressive action of the compression member.
摘要翻译： 用于向患者或从患者输送流体（例如血液）的医疗系统，其包括具有近端的针头，附接到注射器（或其他可比较的流体输送装置）的远端，中间部分和内部通道。 中间部分的横截面为椭圆形，具有双弧形侧壁。 近端钝而圆形。 还包括具有导管的进入位置，导管具有从其向外延伸的弹性管状端口。 该端口包括穿过其中的孔。 端口和孔的横截面均为椭圆形。 在其上具有椭圆形开口的弹性压缩构件定位在端口上以在其上施加压力并关闭孔。 在使用中，针被推入孔中，使压缩构件暂时变形。 在使用注射器（或其他装置）去除或输送流体之后，针通过压缩构件的压缩作用自动密封地从孔中取出。
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86.发明授权公开(公告)号：US09024746B2
公开(公告)日：2015-05-05
申请号：US13618716
申请日：2012-09-14
CPC分类号： G06F19/3406 , A61B5/0077 , A61B5/015 , A61B5/0816 , A61B5/117 , A61B5/746 , A61B5/7475 , A61M1/14 , A61M1/36 , A61M1/367 , A61M2205/18 , A61M2205/3553 , A61M2205/6009 , G05B1/01 , G05B9/02 , G06F19/00 , G06F19/328 , G08B21/182 , G08B21/22 , G16H40/63
摘要： An automatic locking system for a medical treatment device helps to ensure that an assistant is present during treatment of a patient. Among the features disclosed biometric authentication to verify that a trained assistant is present, a presence detector to ensure the assistant is continuously present during treatment, and warning and recovery processes that allow intermittent lapses in the continuous presence of the assistant.
摘要翻译： 用于医疗装置的自动锁定系统有助于确保在治疗患者期间存在助手。 在公开的生物认证的特征中，用于验证训练有素的助理是否存在，在治疗期间确保助理持续存在的存在检测器以及允许在助理持续存在的间歇性失效的警告和恢复过程。
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公开(公告)号：US20140191501A1
公开(公告)日：2014-07-10
申请号：US14123008
申请日：2012-06-08
IPC分类号： F16L35/00
CPC分类号： F16L35/00 , A61M39/1011 , A61M39/105 , A61M2039/1027 , A61M2039/1094 , F16L39/02 , F16L41/023 , F16L2201/10
摘要： The disclosed subject matter includes embodiments of fluid couplings that prevent or discourage misconnection of fluid lines. A coupling device includes multiple male and female connectors that are joined to a common line. The coupling device is mated to a matching coupling device only when all the multiple male and female connectors are property joined. If any of the connectors is not property mated to a corresponding one, the coupling will leak. The coupling devices are made unique by providing an arrangement the connectors, number of connectors, shape of connectors or arrangement of interfering connector parts that ensure that any attempt to improperly couple two fluid lines will result in the incomplete mating of one or more of the connectors and thereby cause leakage of the fluid, failure of the coupling to engage, or otherwise cause the attempt to connect to fail.
摘要翻译： 所公开的主题包括防止或阻止流体管线错误连接的流体联接器的实施例。 联接装置包括连接到公共线的多个公连接器和阴连接器。 只有当所有多个公母连接器属性连接时，联接装置才匹配到匹配的联接装置。 如果任何一个连接器不属于相应的连接器，则联轴器将泄漏。 耦合装置通过提供连接器，连接器的数量，连接器的形状或干扰连接器部件的布置的布置而被制成是独特的，其确保任何不正确地耦合两条流体管线的尝试将导致一个或多个连接器的不完全配合 从而导致流体泄漏，联接器失效，或者导致连接失败的尝试。
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公开(公告)号：US08608658B2
公开(公告)日：2013-12-17
申请号：US13406332
申请日：2012-02-27
IPC分类号： G08B19/00
CPC分类号： A61M1/10 , A61M1/1006 , A61M1/1086 , A61M1/14 , A61M1/1611 , A61M1/1692 , A61M1/34 , A61M1/3403 , A61M1/3607 , A61M1/3609 , A61M1/3621 , A61M1/3626 , A61M1/3639 , A61M1/3653 , A61M1/3655 , A61M1/3656 , A61M1/3659 , A61M2205/15 , A61M2205/18 , A61M2205/33 , A61M2205/3303 , A61M2205/3331 , A61M2205/3344 , A61M2205/3368 , A61M2205/3375 , A61M2205/502 , A61M2230/06 , A61M2230/205 , G01M3/26 , G06F19/00 , G06K9/62 , G06K9/6228 , G06K9/6278 , G06Q50/22 , G08B21/02 , G08B21/0211 , G16H40/63 , G16H50/20
摘要： One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Extracorporeal blood treatment systems draw blood at such a high rate that a loss of integrity in the blood circuit can be serious. There are a number of mechanisms for detecting and preventing leaks, but none is perfect. This tends to limit the use of such equipment in unsupervised settings, such as the home will be limited. Some leak detection schemes can be made sensitive enough to detect the barest of leaks, but when this is done, they result in too many false positives. The invention combines information from multiple inputs to enhance sensitivity in leak detection and reduce the problem of false positives.
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公开(公告)号：US08496625B2
公开(公告)日：2013-07-30
申请号：US13116597
申请日：2011-05-26
IPC分类号： A61M5/32
CPC分类号： A61M25/02 , A61M5/158 , A61M2005/1586 , A61M2005/1588
摘要： A bandage can be used to secure a needle to an access site so as to prevent unintended movement or withdrawal of the needle from the access site during administration of a treatment to a patient. After treatment, the needle can be removed by manipulating a portion of the bandage. Another portion of the bandage can be maintained in position over the access site during needle removal and can be used to promote clotting of the site after needle removal. The bandage may include a clotting agent, a hemostasis pad, and/or a clot-promoting structure. Additionally or alternatively, finger pressure can be applied to the access site through the bandage. For example, the bandage may include a viewing window without any adhesive to allow visual monitoring of the access site during treatment. Finger pressure may be applied to the viewing window and thereby to the access site during and after needle removal to encourage hemostasis.
摘要翻译： 可以使用绷带将针固定到进入位置，以便在给予患者的治疗期间防止针头从进入位置的意外移动或撤回。 治疗后，可以通过操纵绷带的一部分去除针头。 绷带的另一部分可以在针移除期间保持在进入位置上的适当位置，并且可以用于在针移除之后促进部位的凝血。 绷带可以包括凝血剂，止血垫和/或促凝结构。 另外或替代地，手指压力可以通过绷带施加到进入部位。 例如，绷带可以包括没有任何粘合剂的观察窗，以允许在治疗期间对进入部位的视觉监测。 可以将手指压力施加到观察窗，从而在针移除期间和之后到达进入部位以促进止血。
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公开(公告)号：US20130012914A1
公开(公告)日：2013-01-10
申请号：US13545022
申请日：2012-07-10
IPC分类号： A61M1/14
CPC分类号： A61M1/16 , A61M1/1601 , A61M1/1611 , A61M1/1643 , A61M2205/3331 , A61M2205/3334 , A61M2205/3382 , A61M2205/3386 , A61M2205/50 , A61M2205/52
摘要： One or more waste balancing systems may be used in a fluid circulating system for medical use. The fluid circulating system may be part of a blood treatment system for a patient suffering renal failure. A waste balancing system may include a pressure element operable to maintain a constant fluid pressure created by the combined weight of waste removed from a patient and replacement fluid for providing to a patient. Multiple evaluation characteristics or control parameters may be evaluated or controlled for safety and accuracy. At least part of the waste balancing system may be incorporated into a disposable cartridge.
摘要翻译： 在用于医疗用途的流体循环系统中可以使用一个或多个废物平衡系统。 流体循环系统可以是患有肾衰竭的患者的血液处理系统的一部分。 废物平衡系统可以包括压力元件，其可操作以保持由从患者移除的废物的组合重量产生的恒定的流体压力和用于提供给患者的替换流体。 可以评估或控制多个评估特性或控制参数的安全性和准确性。 废物平衡系统的至少一部分可以结合到一次性盒中。
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