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    Devices for marking and defining particular locations in body tissue
    82.
    发明授权
    Devices for marking and defining particular locations in body tissue 失效
    用于标记和定义身体组织中特定位置的装置

    公开(公告)号：US06228055B1

    公开(公告)日：2001-05-08

    申请号：US08858389

    申请日：1997-05-19

    申请人： Seth A. Foerster ,  Fred H. Burbank ,  Mark A. Ritchart ,  Elias A. Zerhouni

    发明人： Seth A. Foerster ,  Fred H. Burbank ,  Mark A. Ritchart ,  Elias A. Zerhouni

    IPC分类号： A61M500

    CPC分类号： A61B19/54 ,  A61B10/0275 ,  A61B10/0283 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2090/3908 ,  A61B2090/3987 ,  Y10T24/4501

    摘要： Implantable devices are disclosed for marking the location of a biopsy or surgery for the purpose of identification. The devices are remotely delivered, preferably percutaneously. Visualization of the markers is readily accomplished using various state of the art imaging systems. Using the inventive systems, it is possible to permanently mark the location or margins of a lesion or other tissue site, prior to removing or sampling same. The markers function to provide evidence of the location of the lesion after the procedure is completed, for reference during future examinations or procedures.

    摘要翻译： 公开了可植入装置，用于标识活检或手术的位置用于鉴定。 这些装置被远程传送，优选经皮。 使用各种现有技术的成像系统可以容易地实现标记的可视化。 使用本发明的系统，可以在移除或取样之前永久地标记病变或其他组织部位的位置或边缘。 标记功能用于在手术完成后提供病变位置的证据，以供将来检查或手术参考。

    Methods and devices for automated biopsy and collection of soft tissue
    83.
    发明授权
    Methods and devices for automated biopsy and collection of soft tissue 失效
    用于自动活检和收集软组织的方法和装置

    公开(公告)号：US5649547A

    公开(公告)日：1997-07-22

    申请号：US386941

    申请日：1995-02-10

    申请人： Mark A. Ritchart ,  J. Michael Stuart ,  Fred H. Burbank ,  Kenneth M. Galt

    发明人： Mark A. Ritchart ,  J. Michael Stuart ,  Fred H. Burbank ,  Kenneth M. Galt

    IPC分类号： A61B10/02 ,  A61B10/00 ,  A61B17/22 ,  A61B17/30 ,  A61B17/34

    CPC分类号： A61B10/0266 ,  A61B10/0275 ,  A61B10/0283 ,  A61B6/12 ,  A61B8/0841 ,  A61B17/221 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/303

    摘要： Instruments for performing percutaneous biopsy procedures are disclosed, which have advantageous features for improving functionality and performance over prior art devices. These instruments comprise two types, single-use devices, and multiple-use devices having active tissue capture capability. Improved features include the ability to retrieve and evaluate multiple tissue samples during a single insertion procedure, without physical handling of the samples, as well as constructional features, such as a molded tissue cassette housing, variant vacuum port embodiments suited for different tissue environments, and a method for backflushing the instrument to remove biological debris, among others.

    摘要翻译： 公开了用于执行经皮活检程序的仪器，其具有改善现有技术装置的功能和性能的有利特征。 这些仪器包括两种类型的一次性装置，以及具有活性组织捕获能力的多用途装置。 改进的特征包括在单次插入过程中检索和评估多个组织样本的能力，而不对样品进行物理处理，以及结构特征，例如模制的组织盒壳体，适合于不同组织环境的变体真空端口实施例，以及 一种反吹仪器以去除生物碎片的方法等。

    Tissue site markers for in vivo imaging
    86.
    发明申请
    Tissue site markers for in vivo imaging 有权
    用于体内成像的组织位点标记

    公开(公告)号：US20100010342A1

    公开(公告)日：2010-01-14

    申请号：US12460052

    申请日：2009-07-13

    申请人： Fred H. Burbank ,  Paul Lubock ,  Micheal L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

    发明人： Fred H. Burbank ,  Paul Lubock ,  Micheal L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

    IPC分类号： A61B8/14

    CPC分类号： A61M37/0069 ,  A61B6/12 ,  A61B8/0833 ,  A61B10/02 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2090/08021 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61K49/006 ,  A61K49/222

    摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

    摘要翻译： 本发明涉及活检部位标记和标记活组织检查部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。 本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。 本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。 标记可以具有不均匀的表面轮廓以增强声学特征。 标记具有在医学成像期间可识别人造的特征形式。 可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活组织腔的迁移。

    Methods and Devices for Automated Biopsy and Collection of Soft Tissue
    87.
    发明申请
    Methods and Devices for Automated Biopsy and Collection of Soft Tissue 失效
    自动活组织检查和软组织收集的方法和装置

    公开(公告)号：US20080154151A1

    公开(公告)日：2008-06-26

    申请号：US11931411

    申请日：2007-10-31

    申请人： Mark A. Ritchart ,  J. Michael Stuart ,  Fred H. Burbank ,  Kenneth M. Galt

    发明人： Mark A. Ritchart ,  J. Michael Stuart ,  Fred H. Burbank ,  Kenneth M. Galt

    IPC分类号： A61B10/04

    CPC分类号： A61B10/0266 ,  A61B6/12 ,  A61B8/0841 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/221 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/303

    摘要： Instruments for performing percutaneous biopsy procedures are disclosed, which have advantageous features for improving functionality and performance over prior art devices. These instruments comprise two types, single-use devices, and multiple-use devices having active tissue capture capability. Improved features include the ability to retrieve and evaluate multiple tissue samples during a single insertion procedure, without physical handling of the samples, as well as constructional features, such as a molded tissue cassette housing, variant vacuum port embodiments suited for different tissue environments, and a method for backflushing the instrument to remove biological debris, among others.

    摘要翻译： 公开了用于执行经皮活检程序的仪器，其具有改善现有技术装置的功能和性能的有利特征。 这些仪器包括两种类型的一次性装置，以及具有活跃组织捕获能力的多用途装置。 改进的特征包括在单次插入过程中检索和评估多个组织样本的能力，而不对样品进行物理处理，以及结构特征，例如模制的组织盒壳体，适合于不同组织环境的变体真空端口实施例，以及 一种反吹仪器以去除生物碎片的方法等。