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89 条记录 (耗时 0.026 秒)

    Implements for identifying sheath migration
    82.
    发明授权
    Implements for identifying sheath migration 有权
    确定皮肤移植的实施

    公开(公告)号：US09492638B2

    公开(公告)日：2016-11-15

    申请号：US14068737

    申请日：2013-10-31

    申请人： Muffin Incorporated

    发明人： Peter S. McKinnis ,  Neal E. Fearnot ,  Kasper Klausen

    IPC分类号： A61M25/02 ,  A61M25/01 ,  A61F2/01 ,  A61B8/12 ,  A61B8/08 ,  A61M25/00 ,  A61B6/12

    CPC分类号： A61M25/0105 ,  A61B6/12 ,  A61B8/0841 ,  A61B8/12 ,  A61B90/94 ,  A61B2050/314 ,  A61B2090/036 ,  A61B2090/0807 ,  A61B2090/0812 ,  A61B2090/3784 ,  A61B2090/3925 ,  A61B2090/3966 ,  A61F2/01 ,  A61F2002/011 ,  A61M2025/0008

    摘要： Attachable implements, systems, and methods for identifying the migration of a medical device extending through a percutaneous insertion site of a patient's skin are disclosed. In one embodiment, an attachable implement for identifying migration comprises a attachable implement body having a coupling surface and a skin contacting surface, the coupling surface arranged to couple to a surface of the medical device, and the skin contacting surface arranged to contact the skin of the patient; wherein the attachable implement body is arranged to be side mountable on the medical device and wherein the attachable implement is configured to move from a first position adjacent to the patient's skin to a second position remote from the patient's skin. Systems, methods, and other embodiments are disclosed.

    摘要翻译： 公开了用于识别延伸穿过患者皮肤的经皮插入部位的医疗装置的迁移的可附接的工具，系统和方法。 在一个实施例中，用于识别迁移的可附接工具包括具有联接表面和皮肤接触表面的可连接工具主体，所述联接表面布置成耦合到医疗装置的表面，以及布置成接触皮肤接触表面的皮肤接触表面 患者; 其中所述可附接工具主体被布置成可侧向安装在所述医疗装置上，并且其中所述可附接工具构造成从邻近所述患者皮肤的第一位置移动到远离所述患者皮肤的第二位置。 公开了系统，方法和其它实施例。

    Medical device design, manufacture and testing systems
    83.
    发明授权
    Medical device design, manufacture and testing systems 有权
    医疗器械设计，制造和检测系统

    公开(公告)号：US09388451B2

    公开(公告)日：2016-07-12

    申请号：US14038080

    申请日：2013-09-26

    申请人： Cook Biotech Incorporated ,  Muffin Incorporated

    发明人： Niraj Ramachandran ,  Frank J. Fischer, Jr. ,  Michael C. Hiles ,  Neal E. Fearnot

    IPC分类号： C12Q1/42 ,  G01N33/50 ,  G01N33/566 ,  A61M25/00

    CPC分类号： C12Q1/42 ,  G01N33/5005 ,  G01N33/5014 ,  G01N33/502 ,  G01N33/566

    摘要： Described are methods and systems for testing lumens of cannulated delivery components or assemblies thereof that may be used to deliver cells to a patient. Test cells are contacted with walls of the lumens and/or liquids that contact walls of the lumens, potentially over an incubation period. The test cells are then assessed for an effect of the wall contact, or the liquid contact, on at least one and preferably multiple characteristics of the test cells such as innate immune response, metabolic activity, viability, cytotoxic response, and/or motility. Methods and systems as described can be used in the development and/or manufacture of cannulated delivery devices, for example providing specifications for design or process inputs or outputs, design or process validations, and/or device lot approvals. Also described are devices or products produced in accordance with such methods and systems.

    摘要翻译： 描述了用于测试可用于将细胞递送至患者的插管输送组件或其组件的腔的方法和系统。 可能在潜伏期内，将测试细胞与腔内壁和/或液体壁接触。 然后评估测试细胞对测试细胞的至少一个优选多个特征（例如先天免疫应答，代谢活性，存活力，细胞毒性反应和/或运动）的壁接触或液体接触的影响。 所描述的方法和系统可以用于开发和/或制造插管式输送装置，例如提供设计或过程输入或输出的规范，设计或过程验证和/或装置批次批准。 还描述了根据这些方法和系统生产的设备或产品。

    ECHOLUCENT GUIDEWIRE TIP
    85.
    发明申请
    ECHOLUCENT GUIDEWIRE TIP 审中-公开
    ECHOLUCENT GUIDEWIRE提示

    公开(公告)号：US20140257090A1

    公开(公告)日：2014-09-11

    申请号：US14196200

    申请日：2014-03-04

    申请人： Muffin Incorporated

    发明人： Frank J. Fischer, JR. ,  Kem Hawkins ,  Neal E. Fearnot

    IPC分类号： A61B8/00 ,  A61M25/09

    CPC分类号： A61B8/42 ,  A61B8/0891 ,  A61B8/445 ,  A61M25/0026 ,  A61M2025/09133

    摘要： A medical device includes a guidewire with a lumen, a plastic tip, and a removable mandrel. The medical device has echogenic properties which can be altered between an echogenic state and an echolucent state by evacuating the lumen and applying a liquid or gas within the lumen.

    摘要翻译： 医疗装置包括具有内腔的导丝，塑料尖端和可移除心轴。 医疗装置具有回声特性，其可以在回声状态和回波状态之间通过抽空腔并在腔内施加液体或气体来改变。

    RECIPROCATING INTERNAL ULTRASOUND TRANSDUCER ASSEMBLY
    86.
    发明申请
    RECIPROCATING INTERNAL ULTRASOUND TRANSDUCER ASSEMBLY 有权
    接收内置超声波传感器总成

    公开(公告)号：US20140107489A1

    公开(公告)日：2014-04-17

    申请号：US14051826

    申请日：2013-10-11

    申请人： Muffin Incorporated

    发明人： Neal E. Fearnot ,  Peter S. McKinnis ,  Sarah Robbins ,  Yun Zhou

    IPC分类号： A61B8/00

    CPC分类号： A61B8/4483 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4461 ,  A61B8/467 ,  A61N7/022 ,  A61N2007/0043 ,  G01S15/894

    摘要： A device for endoluminal therapeutic and diagnostic ultrasound procedures includes a motor which rotates a drive shaft and ultrasound transducer. In one example, conductors attach to the transducer and extend through a hollow drive shaft. In another example, a bias member conducts electric signals and stores energy. The device includes an operational state in which the motor rotates the drive shaft alternatingly between a first direction and an opposite second direction.

    摘要翻译： 用于腔内治疗和诊断超声程序的装置包括使驱动轴和超声换能器旋转的马达。 在一个示例中，导体附接到换能器并延伸穿过中空的驱动轴。 在另一示例中，偏置构件传导电信号并存储能量。 该装置包括操作状态，其中马达在第一方向和相反的第二方向之间交替地旋转驱动轴。

    CATHETER SYSTEMS AND METHODS USEFUL FOR CELL THERAPY
    88.
    发明申请
    CATHETER SYSTEMS AND METHODS USEFUL FOR CELL THERAPY 有权
    导管系统和用于细胞治疗的方法

    公开(公告)号：US20130338637A1

    公开(公告)日：2013-12-19

    申请号：US13910693

    申请日：2013-06-05

    申请人： Muffin Incorporated ,  Cook Medical Technologies LLC

    发明人： Frank J. Fischer, JR. ,  James R. Randolph ,  Neal E. Fearnot ,  Jimmy L. Taylor, JR. ,  Gary Bradford Shirley

    IPC分类号： A61M25/10

    CPC分类号： A61M25/1011 ,  A61B34/20 ,  A61M25/0026 ,  A61M25/0041 ,  A61M25/0068 ,  A61M25/007 ,  A61M25/10 ,  A61M37/0092 ,  A61M2025/0003 ,  A61M2025/0004 ,  A61M2025/0042 ,  A61M2025/1015 ,  A61M2025/1052 ,  A61M2025/1061 ,  A61M2025/1093

    摘要： Described in one aspect is a multi-pressure monitoring system for cell or other therapy includes a first catheter having a first lumen for accepting a treatment device, a second lumen for inflating a balloon, a pressure sensor for monitoring fluid pressure within the first lumen, and a flow restrictor such as a hemostasis valve for limiting the exchange of fluids into and out of the first lumen while treatment devices are present or exchanged in the first lumen. Also disclosed is a method of using the first catheter with a first pressure monitor coupled to the first pressure sensor along with a second catheter attached to a second pressure sensor coupled to a second pressure monitor. The second catheter is positioned within the first lumen of the first catheter during treatment operations and the first and second pressure monitors are used to verify proper pressures throughout the procedure. Described also are novel methods, systems, and catheters for delivering flowable therapeutic substances, such as viable cellular preparations, to patients.

    摘要翻译： 一方面描述了一种用于细胞或其它疗法的多压力监测系统，包括具有用于接受治疗装置的第一腔的第一导管，用于充气气囊的第二腔，用于监测第一腔内的流体压力的压力传感器， 以及限流器，例如止血阀，用于在第一腔内存在或更换治疗装置的同时限制流体进入和离开第一腔的流体。 还公开了一种使用具有耦合到第一压力传感器的第一压力监测器的第一导管以及连接到耦合到第二压力监测器的第二压力传感器的第二导管的方法。 在治疗操作期间，第二导管定位在第一导管的第一腔内，并且在整个过程中使用第一和第二压力监测器来验证适当的压力。 还描述了用于向患者递送可流动治疗物质（例如活细胞制剂）的新颖方法，系统和导管。

    PERCUTANEOUS, ULTRASOUND-GUIDED INTRODUCTION OF MEDICAL DEVICES
    89.
    发明申请
    PERCUTANEOUS, ULTRASOUND-GUIDED INTRODUCTION OF MEDICAL DEVICES 审中-公开
    PERCUTANEOUS，超声引导医疗器械介绍

    公开(公告)号：US20130267848A1

    公开(公告)日：2013-10-10

    申请号：US13731313

    申请日：2012-12-31

    申请人： MUFFIN INCORPORATED

    发明人： Neal E. Fearnot ,  Peter S. McKinnis

    IPC分类号： A61B8/08 ,  A61F2/01

    CPC分类号： A61B8/0841 ,  A61B8/12 ,  A61B34/20 ,  A61B2034/2063 ,  A61B2090/3788 ,  A61B2090/3925 ,  A61B2090/3966 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/008

    摘要： Described are methods and systems and system components useful for percutaneously delivering or retrieving vascular implant devices, such as filters, utilizing intravenous ultrasound (IVUS) imaging alone or in combination with external (e.g. transabdominal) ultrasound or other imaging technology. Implants deliverable by such systems, such as vena cava or other vascular filters, can have two or more echogenic markers spaced at such a distance that they are separately discernible by IVUS and/or external ultrasound imaging.

    摘要翻译： 描述了用于经皮递送或取回血管植入装置（例如滤器）的方法和系统和系统组件，其利用静脉内超声（IVUS）成像单独或与外部（例如经腹）超声或其他成像技术组合。 这种系统可输送的植入物，例如腔静脉或其它血管滤过器可以具有两个或更多个间隔开的间隔的回声标记，以使得它们可被IVUS和/或外部超声成像单独辨别。