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143 条记录 (耗时 0.044 秒)

    Method for prediction of the progression risk of tumors
    82.
    发明授权
    Method for prediction of the progression risk of tumors 有权
    预测肿瘤进展风险的方法

    公开(公告)号：US08728745B2

    公开(公告)日：2014-05-20

    申请号：US13062185

    申请日：2009-09-04

    申请人： Peter Martin ,  Rüdiger Ridder

    发明人： Peter Martin ,  Rüdiger Ridder

    IPC分类号： G01N33/574

    CPC分类号： G01N33/57415 ,  C12Q1/6886 ,  C12Q2600/118 ,  G01N33/57496 ,  G01N2333/4704 ,  G01N2333/4706 ,  G01N2800/50 ,  G01N2800/56

    摘要： The present invention concerns a method for predicting the potential for aggressive growth and/or the risk to progress to high grade cancer for tumors in cell based detection procedures. In one aspect the invention concerns the detection of overexpression of cyclin-dependent kinase inhibitor gene products as a tool for predicting the progression risk and/or potential for aggressive growth of tumors. In a second aspect the invention concerns predicting the progression risk and/or potential for aggressive growth in tumors on the basis of the simultaneous co-detection of the presence of overexpression of cyclin-dependent kinase inhibitor gene products together with the expression of markers for active cell proliferation. Further the invention concerns preparations of probes for diagnosis namely for predicting the progression risk and/or the potential for aggressive growth of tumors.

    摘要翻译： 本发明涉及一种用于在基于细胞的检测程序中预测侵袭性生长的潜力和/或进展为高等级肿瘤的风险的方法。 一方面，本发明涉及检测细胞周期蛋白依赖性激酶抑制剂基因产物的过表达，作为预测肿瘤侵袭性生长的进展风险和/或潜力的工具。 在第二方面，本发明涉及基于同时共检测细胞周期蛋白依赖性激酶抑制剂基因产物的过表达以及活性标志物的表达来预测肿瘤侵袭性生长的进展风险和/或潜力 细胞增殖。 此外，本发明涉及用于诊断的探针的准备，即用于预测肿瘤的进展风险和/或潜在的侵袭性生长。

    Angular contact rolling-element bearing, especially double row ball roller bearing in tandem arrangement
    84.
    发明授权
    Angular contact rolling-element bearing, especially double row ball roller bearing in tandem arrangement 失效
    角接触滚动体轴承，特别是串列排列的双列滚珠轴承

    公开(公告)号：US08425122B2

    公开(公告)日：2013-04-23

    申请号：US12989263

    申请日：2009-04-02

    申请人： Andreas Bohr ,  Horst Doeppling ,  Heinrich Hofmann ,  Peter Martin

    发明人： Andreas Bohr ,  Horst Doeppling ,  Heinrich Hofmann ,  Peter Martin

    IPC分类号： F16C33/36 ,  F16C19/38

    CPC分类号： F16C19/38 ,  F16C19/505 ,  F16C33/36 ,  F16C33/485 ,  F16C33/585

    摘要： A double row roller bearing which has an outer and inner bearing ring and ball rollers, which have lateral faces and are arranged next to each other in rows, arranged between the bearing rings. The rollers roll in raceways incorporated into the inner face of the outer bearing ring and outer face of the inner hearing ring. The raceways run in parallel and have pressure angle axes that are pitched at a pressure angle relative to a bearing radial axis. The rollers have a distance relative to each other which excludes mutual frictional contacts. For this purpose, the distance of the pressure angle axes of the raceways is enlarged and both rows of rollers are guided in separate bearing cages, while the raceway of the rollers of the row with the larger reference circle arranged on the inner bearing ring has a one-sided axial extension using the distance.

    摘要翻译： 一种双列滚子轴承，其具有设置在轴承环之间的具有侧面并彼此排列配置的外轴承环和内轴承圈和滚珠滚子。 滚子滚动在并入外轴承环的内表面和内听筒外表面的滚道中。 滚道平行运行并具有相对于轴承径向轴线以压力角倾斜的压力角轴。 辊子具有相对于彼此的距离，排除相互摩擦接触。 为此，滚道的压力角轴线的距离增大，两列滚子分开的轴承保持架被引导，而排列在内轴承环上的具有较大基准圆的列的滚道的滚道具有 单向轴向延伸使用距离。

    Snapshot pixel circuit for minimizing leakage current in an imaging sensor having a two-pole integration switch
    85.
    发明授权
    Snapshot pixel circuit for minimizing leakage current in an imaging sensor having a two-pole integration switch 失效
    用于使具有两极集成开关的成像传感器中的漏电流最小化的快照像素电路

    公开(公告)号：US08330092B2

    公开(公告)日：2012-12-11

    申请号：US12658271

    申请日：2010-02-09

    申请人： Peter Martin ,  Paul Johnson ,  Chris Sexton

    发明人： Peter Martin ,  Paul Johnson ,  Chris Sexton

    IPC分类号： H01J40/14

    CPC分类号： H04N5/37452 ,  H01L27/14609 ,  H04N5/3532 ,  H04N5/357

    摘要： Pixel circuits, capable of operating in either “snapshot” or “rolling integration” mode, and compatible with a conformal photodiode coating. Preferred embodiments of the present invention are compatible with these coating materials, as well as others, including amorphous Silicon. The preferred pixel circuits includes additional transistors not provided in prior art pixel circuits to divert leakage current away from integration nodes when not integrating, to reset the integration node, and to buffer and select the integrated voltage.

    摘要翻译： 像素电路，能够以快照或滚动集成模式运行，并且与保形光电二极管涂层兼容。 本发明的优选实施方案与这些涂层材料以及包括无定形硅在内的其它涂层材料相兼容。 优选的像素电路包括现有技术的像素电路中未提供的额外的晶体管，用于在不积分时将漏电流转移离开集成节点，复位积分节点，并缓冲并选择积分电压。

    Reinforced connector
    86.
    发明授权
    Reinforced connector 有权
    加强连接器

    公开(公告)号：US08092409B2

    公开(公告)日：2012-01-10

    申请号：US11750452

    申请日：2007-05-18

    申请人： Henry Mros ,  Peter Martin

    发明人： Henry Mros ,  Peter Martin

    IPC分类号： A61H23/00 ,  A61F5/00

    CPC分类号： A61H1/008 ,  A61M39/12 ,  A61M2039/1027 ,  A61M2039/1083 ,  A61M2039/1088 ,  F16L37/56 ,  F16L39/02 ,  Y10T403/1616

    摘要： A connector for attaching a flexible tube to a fluid passage of another object includes a housing and a connector port on the body. The connector port is sized and shaped for connecting the connector port in fluid communication with the fluid passage of the object. The connector includes a tube port projecting from the body. The tube port is adapted for fluid communication with the connector port and is sized and shaped for being received in an end of the flexible tube to establish fluid communication with the flexible tube. The tube port includes a tube retainer that projects from the body toward the tube port. The retainer has an engaging end portion disposed in relation to the tube port to engage the flexible tube when the tube port is received in the flexible tube. The flexible tube is restrained from lateral movement with respect to the tube port.

    摘要翻译： 用于将柔性管附接到另一物体的流体通道的连接器包括壳体和主体上的连接器端口。 连接器端口的尺寸和形状用于连接与物体的流体通道流体连通的连接器端口。 连接器包括从主体突出的管端口。 管端口适于与连接器端口流体连通，并且其尺寸和形状适于容纳在柔性管的端部中以与柔性管建立流体连通。 管口包括从本体朝向管口突出的管保持器。 当所述管口容纳在所述柔性管中时，所述保持器具有相对于所述管端口设置的接合端部，以与所述柔性管接合。 柔性管相对于管口被限制在横向运动。

    METHOD FOR PREDICTION OF THE PROGRESSION RISK OF TUMORS
    88.
    发明申请
    METHOD FOR PREDICTION OF THE PROGRESSION RISK OF TUMORS 有权
    预测肿瘤进展风险的方法

    公开(公告)号：US20110183333A1

    公开(公告)日：2011-07-28

    申请号：US13062185

    申请日：2009-09-04

    申请人： Peter Martin ,  Rüdiger Ridder

    发明人： Peter Martin ,  Rüdiger Ridder

    IPC分类号： C12Q1/68 ,  G01N33/53

    CPC分类号： G01N33/57415 ,  C12Q1/6886 ,  C12Q2600/118 ,  G01N33/57496 ,  G01N2333/4704 ,  G01N2333/4706 ,  G01N2800/50 ,  G01N2800/56

    摘要： The present invention concerns a method for predicting the potential for aggressive growth and/or the risk to progress to high grade cancer for tumors in cell based detection procedures. In one aspect the invention concerns the detection of overexpression of cyclin-dependent kinase inhibitor gene products as a tool for predicting the progression risk and/or potential for aggressive growth of tumors. In a second aspect the invention concerns predicting the progression risk and/or potential for aggressive growth in tumors on the basis of the simultaneous co-detection of the presence of overexpression of cyclin-dependent kinase inhibitor gene products together with the expression of markers for active cell proliferation. Further the invention concerns preparations of probes for diagnosis namely for predicting the progression risk and/or the potential for aggressive growth of tumors.

    摘要翻译： 本发明涉及一种用于在基于细胞的检测程序中预测侵袭性生长的潜力和/或进展为高等级肿瘤的风险的方法。 一方面，本发明涉及检测细胞周期蛋白依赖性激酶抑制剂基因产物的过表达，作为预测肿瘤侵袭性生长的进展风险和/或潜力的工具。 在第二方面，本发明涉及基于同时共检测细胞周期蛋白依赖性激酶抑制剂基因产物的过表达以及活性标志物的表达来预测肿瘤侵袭性生长的进展风险和/或潜力 细胞增殖。 此外，本发明涉及用于诊断的探针的准备，即用于预测肿瘤的进展风险和/或潜在的侵袭性生长。

    PROCESS AND SYSTEM FOR DETERMINING THE POSITION AND VELOCITY OF AN OBJECT
    89.
    发明申请
    PROCESS AND SYSTEM FOR DETERMINING THE POSITION AND VELOCITY OF AN OBJECT 审中-公开
    确定对象位置和速度的过程和系统

    公开(公告)号：US20110095939A1

    公开(公告)日：2011-04-28

    申请号：US12995594

    申请日：2009-06-09

    申请人： Peter Martin ,  Adam Bryce Maclean

    发明人： Peter Martin ,  Adam Bryce Maclean

    IPC分类号： G01S13/42 ,  G01S15/42

    CPC分类号： G01S13/227 ,  G01S13/582

    摘要： A process for determining the position and velocity of an object is disclosed. The process comprises: -generating a first burst of pulses at a first pulse repetition frequency and subsequently receiving a first set of signals characteristic of the range and velocity of the object; -generating a second burst of pulses at a second pulse repetition frequency and subsequently receiving a second set of signals characteristic of range and velocity of the object; -generating a first data set representative of range and corresponding velocity values from the first set of signals; -generating a second data set representative of range and corresponding velocity values from the second set of signals; -summing a magnitude of a signal strength from each of the first and second data sets at corresponding range and velocity values; and, -comparing the magnitude of the summed signal strengths to a threshold value.

    摘要翻译： 公开了一种用于确定物体的位置和速度的过程。 该过程包括： - 以第一脉冲重复频率产生第一脉冲串，随后接收特征为对象的范围和速度的第一组信号; - 以第二脉冲重复频率产生第二脉冲串，随后接收特征为所述对象的范围和速度的第二组信号; - 从第一组信号产生表示范围和相应速度值的第一数据集; - 产生代表来自所述第二组信号的范围和对应速度值的第二数据集; 在对应的范围和速度值下，从第一和第二数据组中的每个数据集中的信号强度的大小; 并且将相加的信号强度的幅度与阈值进行比较。