公开(公告)号：US20060222629A1

公开(公告)日：2006-10-05

申请号：US11317548

申请日：2005-12-23

Applicant: David Weiner ,  William Williams ,  Bin Wang

Inventor： David Weiner ,  William Williams ,  Bin Wang

IPC: A61K48/00 ,  A61K39/12 ,  A61K31/44 ,  A61K31/40 ,  A61K31/138 ,  A61K31/137

CPC classification number: A61K38/193 ,  A61K39/00 ,  A61K39/0011 ,  A61K39/0225 ,  A61K39/12 ,  A61K39/205 ,  A61K39/21 ,  A61K39/29 ,  A61K39/292 ,  A61K48/0008 ,  A61K2039/53 ,  A61K2039/545 ,  A61K2039/55511 ,  A61K2039/55566 ,  C07K14/005 ,  C12N15/87 ,  C12N2730/10122 ,  C12N2730/10134 ,  C12N2740/13022 ,  C12N2740/16122 ,  C12N2740/16134 ,  C12N2740/16222 ,  C12N2740/16234 ,  C12N2740/16322 ,  C12N2740/16334 ,  C12N2760/20122 ,  C12N2760/20134 ,  C12N2770/24222 ,  C12N2770/24234 ,  Y02A50/464 ,  Y02A90/26

Abstract: Methods of introducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a polynucleotide function enhancer and administering to the cells, a nucleic acid molecule that is free of retroviral particles. The nucleic acid molecule comprises a nucleotide sequence that encodes a protein that comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen or an antigen associated with a hyperproliferative or autoimmune disease, a protein otherwise missing from the individual due to a missing, non-functional or partially functioning gene, or a protein that produces a therapeutic effect on an individual. Methods of prophylactically and therapeutically immunizing an individual against HIV am disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.

Abstract translation: 公开了将遗传物质引入个体细胞的方法和用于实施其的组合物和试剂盒。 所述方法包括使个体的细胞与多核苷酸功能增强子接触并向细胞施用不含逆转录病毒颗粒的核酸分子的步骤。 核酸分子包含编码蛋白质的核苷酸序列，该蛋白质包含与病原体抗原或与过度增殖或自身免疫疾病相关的抗原的表位相同或基本相似的至少一个表位， 涉及缺失的，非功能的或部分功能的基因或对个体产生治疗作用的蛋白质。 公开了预防和治疗个体免受HIV的方法。 公开了用于本发明的实践方法的药物组合物和试剂盒。

公开(公告)号：US20060209598A1

公开(公告)日：2006-09-21

申请号：US11084214

申请日：2005-03-17

Applicant: Bin Wang ,  Chih-Hsin Wang ,  William Colleran

Inventor： Bin Wang ,  Chih-Hsin Wang ,  William Colleran

IPC: G11C16/04

CPC classification number: G11C16/10

Abstract: NVM arrays include rows and columns of NVM cells comprising a floating gate, dual transistor, inverter storage element. Supply voltage for selected storage elements is turned off during a programming and an erase mode. Isolation transistors for each NVM cell or for each row of NVM cells may be used to control the supply voltage.

Abstract translation: NVM阵列包括包括浮动栅极，双晶体管，逆变器存储元件的NVM单元的行和列。 在编程和擦除模式期间，所选存储元件的电源电压关闭。 可以使用每个NVM单元或每行NVM单元的隔离晶体管来控制电源电压。

公开(公告)号：US06197755B1

公开(公告)日：2001-03-06

申请号：US09321461

申请日：1999-05-27

Applicant: Richard A. Carrano ,  Bin Wang ,  David B. Weiner

Inventor： Richard A. Carrano ,  Bin Wang ,  David B. Weiner

IPC: A61K317088

CPC classification number: C07K14/005 ,  A61K38/193 ,  A61K39/0011 ,  A61K39/0225 ,  A61K39/12 ,  A61K39/21 ,  A61K39/29 ,  A61K39/292 ,  A61K48/00 ,  A61K2039/53 ,  A61K2039/55511 ,  A61K2039/55522 ,  C12N15/85 ,  C12N15/87 ,  C12N2730/10134 ,  C12N2740/14022 ,  C12N2740/14034 ,  C12N2740/15034 ,  C12N2740/16134 ,  C12N2740/16222 ,  C12N2740/16234 ,  C12N2770/24034 ,  C12N2770/24222 ,  C12N2770/24234 ,  C12N2800/108 ,  Y02A50/464

Abstract: Methods of introducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a genetic vaccine facilitator and administering to the cells, a nucleic acid molecule that is free of retroviral particles. The nucleic acid molecule comprises a nucleotide sequence that encodes a protein that comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen or an antigen associated with a hyperproliferative or autoimmune disease, a protein otherwise missing from the individual due to a missing, non-functional or partially functioning gene, or a protein that produce a therapeutic effect on an individual. Methods of prophylactically and therapeutically immunizing an individual against HIV are disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.

Abstract translation: 公开了将遗传物质引入个体细胞的方法和用于实施其的组合物和试剂盒。 所述方法包括使个体的细胞与基因疫苗促进剂接触并向细胞施用不含逆转录病毒颗粒的核酸分子的步骤。 核酸分子包含编码蛋白质的核苷酸序列，该蛋白质包含与病原体抗原或与过度增殖或自身免疫疾病相关的抗原的表位相同或基本相似的至少一个表位， 涉及缺失的，非功能的或部分功能的基因或对个体产生治疗作用的蛋白质。 公开了预防和治疗个体免受HIV感染的方法。 公开了用于本发明的实践方法的药物组合物和试剂盒。

公开(公告)号：US6022595A

公开(公告)日：2000-02-08

申请号：US792044

申请日：1997-01-31

Applicant: John F. McDonald ,  Toh-Ming Lu ,  Bin Wang ,  Guang Rong Yang

Inventor： John F. McDonald ,  Toh-Ming Lu ,  Bin Wang ,  Guang Rong Yang

IPC: B05D1/00 ,  B05D7/24 ,  C23C16/44 ,  C08J7/06

CPC classification number: B05D1/60 ,  C23C16/44 ,  B05D1/007

Abstract: A method of depositing a polymer film onto a semiconductor wafer is provided which includes the steps of connecting the wafer to one terminal of a voltage source, connecting an electrode to an other pole of the voltage source and placing the electrode and substrate in superposed orientation to form a parallel plate capacitor, wherein an electric field is produced between the electrode and substrate. The parallel plate capacitor is placed in a chamber where pressure andc temperature are maintained at predetermined levels and gaseous monomers of the desired film to be polymerized are introduced into the chamber. The gaseous monomers are then permitted to flow between the electrode and wafer while the voltage of the electric field is maintained at a level sufficient to polarize the monomers without breaking their chemical bonds wherein the polarized monomers react to form a polymer film on the wafer at an enhanced rate.

Abstract translation: 提供了一种在半导体晶片上沉积聚合物膜的方法，其包括以下步骤：将晶片连接到电压源的一个端子，将电极连接到电压源的另一个极，并将电极和衬底放置成叠置的方向 形成平行板电容器，其中在电极和基板之间产生电场。 将平行板电容器放置在压力和温度保持在预定水平的室中，并将待聚合的所需膜的气态单体引入室中。 然后允许气态单体在电极和晶片之间流动，同时电场的电压保持在足以使单体极化的水平，而不破坏其化学键，其中极化单体在晶片上反应形成聚合物膜， 增加率。

公开(公告)号：US5817637A

公开(公告)日：1998-10-06

申请号：US783818

申请日：1997-01-13

Applicant: David B. Weiner ,  William V. Williams ,  Bin Wang

Inventor： David B. Weiner ,  William V. Williams ,  Bin Wang

IPC: A61K48/00 ,  A61K39/00 ,  A61K39/12 ,  A61K39/21 ,  C07K14/16 ,  C12N15/87 ,  A61K45/05 ,  A61K31/00

CPC classification number: C07K14/005 ,  A61K39/00 ,  A61K39/12 ,  A61K39/21 ,  C12N15/87 ,  A61K2039/53 ,  C12N2740/16034 ,  C12N2740/16122 ,  C12N2740/16134 ,  C12N2740/16222 ,  C12N2740/16234 ,  C12N2740/16322 ,  C12N2740/16334 ,  Y10S435/975 ,  Y10S514/818

Abstract: Methods of prophylactic and therapeutic immunization of an individual against pathogen infection, diseases associated with hyperproliferative cells and autoimmune diseases are disclosed. The methods comprise the steps of administering to cells of an individual, a nucleic acid molecule that comprises a nucleotide sequence that encodes a protein which comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen, a hyperproliferative cell associated protein or a protein associated with autoimmune disease respectively. In each case, nucleotide sequence is operably linked to regulatory sequences to enable expression in the cells. The nucleic acid molecule is free of viral particles and capable of being expressed in said cells. The cells may be contacted cells with a cell stimulating agent. Methods of prophylactically and therapeutically immunizing an individual against HIV are disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.

Abstract translation: 公开了个体对病原体感染的预防和治疗免疫的方法，与过度增殖细胞和自身免疫疾病相关的疾病。 所述方法包括对个体的细胞施用包含编码蛋白质的核苷酸序列的核酸分子的步骤，所述核苷酸序列包含与病原体抗原的表位相同或基本上相似的至少一个表位，相关的过度增殖细胞 蛋白质或与自身免疫疾病相关的蛋白质。 在每种情况下，核苷酸序列可操作地连接到调节序列以使得能够在细胞中表达。 核酸分子不含病毒颗粒，能够在所述细胞中表达。 细胞可以与细胞刺激剂接触细胞。 公开了预防和治疗个体免受HIV感染的方法。 公开了用于本发明的实践方法的药物组合物和试剂盒。

公开(公告)号：USD956306S1

公开(公告)日：2022-06-28

申请号：US29769045

申请日：2021-02-03

Applicant: Bin Wang

Designer： Bin Wang

公开(公告)号：US09975967B2

公开(公告)日：2018-05-22

申请号：US13409735

申请日：2012-03-01

Applicant: Charles Michael Buchanan ,  Michael Eugene Donelson ,  Elizabeth Guzman-Morales ,  Peter Borden Mackenzie ,  Bin Wang

Inventor： Charles Michael Buchanan ,  Michael Eugene Donelson ,  Elizabeth Guzman-Morales ,  Peter Borden Mackenzie ,  Bin Wang

IPC: G02F1/1335 ,  C08B3/16 ,  C08J5/18 ,  C08L1/14 ,  G02B1/04 ,  C08B3/00 ,  C08B3/06 ,  C08B3/08 ,  G02F1/13363

CPC classification number: C08B3/16 ,  B32B2457/202 ,  C08B3/00 ,  C08B3/06 ,  C08B3/08 ,  C08J5/18 ,  C08J2301/14 ,  C08L1/14 ,  G02B1/04 ,  G02F1/13363 ,  G02F2001/133631 ,  Y10T428/10 ,  Y10T428/1036 ,  Y10T428/105

Abstract: Regioselectively substituted cellulose esters having a plurality of aryl-acyl substituents and a plurality of alkyl-acyl substituents are disclosed along with methods for making the same. Such cellulose esters may be suitable for use in optical films, such as optical films having certain Nz values, −A optical films, and/or +C optical films. Optical films prepared employing such cellulose esters have a variety of commercial applications, such as, for example, as compensation films in liquid crystal displays and/or waveplates in creating circular polarized light used in 3-D technology.

公开(公告)号：US09956340B2

公开(公告)日：2018-05-01

申请号：US14307063

申请日：2014-06-17

Applicant: Bin Wang ,  Jason Shih ,  Gregory Harbers ,  Fukang Jiang ,  Sean Caffey

Inventor： Bin Wang ,  Jason Shih ,  Gregory Harbers ,  Fukang Jiang ,  Sean Caffey

IPC: A61M5/155 ,  A61M31/00 ,  A61L31/14 ,  A61L31/04 ,  A61M5/142 ,  A61M5/145

CPC classification number: A61M5/155 ,  A61L31/048 ,  A61L31/14 ,  A61M5/14212 ,  A61M5/14276 ,  A61M5/14593 ,  A61M31/002 ,  A61M2005/14204

Abstract: An implantable device has an outer shell that includes an aperture through the housing of the device and, spanning the aperture, a membrane structure permeable to gas but not to liquid. In this way, excess gas may be vented from the device. The membrane and aperture are designed to discourage or even prevent tissue ingrowth.

公开(公告)号：US09917874B2

公开(公告)日：2018-03-13

申请号：US12887483

申请日：2010-09-21

Applicant: Michael G. Luby ,  Mark Watson ,  Payam Pakzad ,  Bin Wang

Inventor： Michael G. Luby ,  Mark Watson ,  Lorenzo Vicisano ,  Payam Pakzad ,  Bin Wang

IPC: G06F15/16 ,  H04L29/06 ,  H04N21/231 ,  H04N21/234 ,  H04N21/2343 ,  H04N21/235 ,  H04N21/258 ,  H04N21/2662 ,  H04N21/435 ,  H04N21/44 ,  H04N21/4402 ,  H04N21/442 ,  H04N21/84 ,  H04N21/845 ,  H04N21/24

CPC classification number: H04L65/604 ,  H04L65/4084 ,  H04L65/602 ,  H04L65/607 ,  H04L65/80 ,  H04N21/23106 ,  H04N21/23406 ,  H04N21/234327 ,  H04N21/235 ,  H04N21/2401 ,  H04N21/25808 ,  H04N21/2662 ,  H04N21/435 ,  H04N21/44004 ,  H04N21/440227 ,  H04N21/44209 ,  H04N21/84 ,  H04N21/8456

Abstract: A block-request streaming system provides for improvements in the user experience and bandwidth efficiency of such systems, typically using an ingestion system that generates data in a form to be served by a conventional file server (HTTP, FTP, or the like), wherein the ingestion system intakes content and prepares it as files or data elements to be served by the file server. A client device can be adapted to take advantage of the ingestion process. The client device might be configured to optimize use of resources, given the information available to it from the ingestion system. This may include configurations to determine the sequence, timing and construction of block requests based on monitoring buffer size and rate of change of buffer size, use of variable sized requests, mapping of block requests to underlying transport connections, flexible pipelining of requests, and/or use of whole file requests based on statistical considerations.

公开(公告)号：US09796791B2

公开(公告)日：2017-10-24

申请号：US13409747

申请日：2012-03-01

Applicant: Charles Michael Buchanan ,  Michael Eugene Donelson ,  Elizabeth Guzman-Morales ,  Peter Borden Mackenzie ,  Bin Wang

Inventor： Charles Michael Buchanan ,  Michael Eugene Donelson ,  Elizabeth Guzman-Morales ,  Peter Borden Mackenzie ,  Bin Wang

IPC: C09K19/02 ,  C08B3/16 ,  C08J5/18 ,  C08L1/14 ,  G02B1/04 ,  C08B3/00 ,  C08B3/06 ,  C08B3/08

CPC classification number: C08B3/16 ,  B32B2457/202 ,  C08B3/00 ,  C08B3/06 ,  C08B3/08 ,  C08J5/18 ,  C08J2301/14 ,  C08L1/14 ,  G02B1/04 ,  G02F1/13363 ,  G02F2001/133631 ,  Y10T428/10 ,  Y10T428/1036 ,  Y10T428/105

Abstract: Regioselectively substituted cellulose esters having a plurality of aryl-acyl substituents and a plurality of alkyl-acyl substituents are disclosed along with methods for making the same. Such cellulose esters may be suitable for use in optical films, such as optical films having certain Nz values, −A optical films, and/or +C optical films. Optical films prepared employing such cellulose esters have a variety of commercial applications, such as, for example, as compensation films in liquid crystal displays and/or waveplates in creating circular polarized light used in 3-D technology.