公开(公告)号：US20230248977A1

公开(公告)日：2023-08-10

申请号：US18107341

申请日：2023-02-08

Applicant: Boston Scientific Neuromodulation Corporation

Inventor： Rosana Esteller ,  Andrew James Haddock ,  Mahsa Malekmohammadi ,  Tianhe Zhang ,  Venugopal Allavatam

IPC: A61N1/36 ,  A61B5/388 ,  A61B5/11

CPC classification number: A61N1/36139 ,  A61B5/388 ,  A61N1/3614 ,  A61B5/1101

Abstract: This document discusses a computer-implemented method of calibration of an implantable neurostimulation device. The method includes sensing one or more symptoms of a neurological condition of a subject using a sensor external to the neurostimulation device; delivering neurostimulation to the subject using the neurostimulation device and adjusting neurostimulation parameters based on the sensed symptom; sensing one or more neural response signals resulting from the neurostimulation using a sensor of the neurostimulation device; correlating the sensed symptom with the one or more sensed neural response signals; determining a target neural response using the correlating; and recurrently adjusting the neurostimulation parameters according to a comparison of subsequently sensed neural response signals to the target neural response signal.

公开(公告)号：US20230144889A1

公开(公告)日：2023-05-11

申请号：US17980325

申请日：2022-11-03

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Hyun-joo Park

IPC: A61N1/36 ,  A61B5/388

CPC classification number: A61N1/36071 ,  A61B5/388 ,  A61N1/36062 ,  A61N1/36178

Abstract: In some embodiments, a method of providing a neurostimulation therapy to a patient, comprises: generating electrical pulses, by an implantable pulse generator (IPG), comprising respective bursts of a plurality of anodic pulses with each anodic pulse being separated by a time gap, wherein (1) the plurality of anodic pulses comprise successively increasing charge; (2) the plurality of anodic pulses are charge limited to be sub-threshold; (3) each burst of anodic pulses is followed by a discharge phase of intermittent time periods to discharge charge build up from the anodic pulses; and (4) each successive intermittent time period increases in time through the discharge phase to avoid action potential (AP) generation; and applying the generated electrical pulses to neural tissue of the patient to inhibit neural activity of the patient.

公开(公告)号：US20230139116A1

公开(公告)日：2023-05-04

申请号：US17897864

申请日：2022-08-29

Applicant: Cornell University

Inventor： Jeremy B. WIYGUL ,  Saie Milind GANOO ,  Rohit CURUCUNDHI

IPC: A61B5/391 ,  A61B5/395 ,  A61B5/296 ,  A61B5/397 ,  A61B5/313 ,  A61B5/388 ,  A61B5/00 ,  A61B5/22 ,  A61N1/36 ,  A63B23/20

Abstract: A computer-implemented method for pelvic floor feedback. The method includes capturing a strength of action potentials via wireless sensors, the wireless sensors positioned proximate to a pelvic floor of a user. The method also includes transmitting the strength of the action potentials to a mobile device. The method also includes recording the strength of the action potentials on the mobile device.

公开(公告)号：US20230113963A1

公开(公告)日：2023-04-13

申请号：US17496898

申请日：2021-10-08

Applicant: GE Precision Healthcare LLC

Inventor： Jami Matti Jormakka

IPC: A61B5/11 ,  A61B5/00 ,  A61B5/395 ,  A61B5/388 ,  A61B5/30

Abstract: A kinemyography sensor includes a support frame and a flexible substrate, wherein at least a portion of the flexible substrate is attached to the support frame. The support frame is configured to attach to a patient's thumb and forefinger and has a bendable middle section configured to bend in response to movement of the patient's thumb. A printed stimulation circuit is printed on the substrate and includes a pair of stimulation electrodes configured to adhere to a patient's skin to deliver a kinemyography stimulus, and a printed bend sensor is printed on the substrate and located on the bendable middle section of the support frame, wherein the printed bend sensor is configured to sense the bending of the support frame.

公开(公告)号：US11589827B2

公开(公告)日：2023-02-28

申请号：US16622675

申请日：2018-06-22

Applicant: GALVANI BIOELECTRONICS LIMITED ,  UCL BUSINESS LTD

Inventor： Kirill Aristovich ,  David Holder ,  Daniel Chew ,  Matteo Donega

IPC: A61B5/00 ,  G16H20/30 ,  G16H40/67 ,  G16H50/20 ,  A61B5/11 ,  A61N1/36 ,  A61B5/388 ,  A61N1/05

Abstract: There is provided a nerve activity monitoring method that includes receiving an input signal indicative of activity in a nerve of a subject; receiving physiological data indicative of physiological activity in the subject; establishing a relationship between the physiological data and the input signal; identifying a plurality of periodic portions in the input signal based on the relationship between the physiological data and the input signal; and outputting the periodic portions identified.

公开(公告)号：US11517753B2

公开(公告)日：2022-12-06

申请号：US17175794

申请日：2021-02-15

Applicant: Donald A. Rhodes

Inventor： Donald A. Rhodes

IPC: A61N1/00 ,  A61N1/36 ,  A61B5/01 ,  A61B5/0531 ,  A61B5/00 ,  A61N1/04 ,  A61B5/388

Abstract: An electrical interferential technique is used to determine operable treatment parameters which are then used to apply a treatment to a patient. A range of beat frequencies is applied to the patient and an indicator of autonomic nervous system activity is measured. When some degree of autonomic nervous system activity is detected, a subsequent trial is conducted using an overlaying range of frequencies, a narrower range or a single frequency, in an attempt to fine tune the reaction of the autonomic nervous system. The subsequent trial may use a different measure of activity of the autonomic nervous system. A garment having a series of electrode sites thereon may be used for a partially trained person to correctly apply electrodes to the patient's body. The treatments may be conducted while the patient is asleep.

公开(公告)号：US20220296156A1

公开(公告)日：2022-09-22

申请号：US17805858

申请日：2022-06-07

Applicant: JIANGSU BAINING YINGCHUANG MEDICAL TECHNOLOGY CO., LTD.

Inventor： Zhigang SHI ,  Jiancong LI

IPC: A61B5/388 ,  A61B5/00 ,  A61B5/389 ,  A61B34/20

Abstract: The present disclosure relates to a neuromonitoring device. The neuromonitoring device may include a probe, an operation part, and a display part. The probe may include a probe head, an elastic piece, and an elastic measuring piece. The probe head may be connected to the elastic piece. The elastic measuring piece may be connected to the elastic piece and may be used to measure an elasticity value of the elastic piece and convert the elasticity value into a first electrical signal. The display part may be configured to display prompt information. The prompt information may include prompt information regarding the elasticity value determined based on the first electrical signal.

公开(公告)号：US20220233131A1

公开(公告)日：2022-07-28

申请号：US17649164

申请日：2022-01-27

Applicant: Winfried Raabe

Inventor： Winfried Raabe

IPC: A61B5/388 ,  A61B5/262 ,  A61B5/294 ,  A61B5/00 ,  A61B5/397

Abstract: A method may include obtaining first and second time series (TS1), (TS2) of stimulation data, and a first and second time series of control data. TS1, TS2 may provide a plurality of pairs of data points such that each of the plurality of pairs include corresponding data points from both TS1 and TS2. The obtained time series may be analyzed by applying an algorithm (Alg) to TS1 and TS2 of stimulation data to create an algorithm value corresponding to each of the plurality of pairs of data points. Alg=(|TS1|+|TS2|)/2−|TS1−TS2|. Positive algorithm values for a predetermined period of time (AlgVarTime) may be summed to create a signal. Peak(s) in the signal may be determined, and a conduction velocity may be determined using a latency and a distance between a stimulus electrode and a recording electrode.

公开(公告)号：US20220208338A1

公开(公告)日：2022-06-30

申请号：US17136090

申请日：2020-12-29

Applicant: KPN INNOVATIONS, LLC.

Inventor： Kenneth Neumann

IPC: G16H20/60 ,  G16H50/20 ,  G16H10/60 ,  G16H50/70 ,  G16H40/67 ,  G06N3/04 ,  A61B5/388 ,  A61B5/00

Abstract: A system and method for generating a neuropathologic nourishment program comprises a computing device configured to obtain a neural element from a neural monitoring component, generate at least a neural profile as a function of the neural element, wherein generating comprises receiving at least a neural cluster as a function of a neural counsel, and generating the neural profile as a function of the neural cluster and neural element using a neural machine-learning model, identify at least an edible as a function of the neural profile, wherein identifying comprises obtaining a nourishment composition from an edible directory, determining a nourishment abnormality as a function of the neural profile and a normal range, and identifying an edible using the nourishment composition, nourishment abnormality, and an edible machine-learning model, and generate a nourishment program of a plurality of nourishment programs as a function of the edible.

公开(公告)号：US12226632B2

公开(公告)日：2025-02-18

申请号：US18175963

申请日：2023-02-28

Applicant: EMKinetics, Inc.

Inventor： Amit Rajguru ,  Daniel R. Burnett ,  Alexander Vergara ,  Michael Hemati

IPC: A61N1/36 ,  A61B5/388 ,  A61N1/04 ,  A61N2/02 ,  A61B5/00 ,  A61N1/05 ,  A61N1/378 ,  A61N2/00

Abstract: The disclosure describes devices and methods for providing transdermal electrical stimulation therapy to a subject including positioning a stimulator electrode over a glabrous skin surface overlying a palm of the subject and delivering electrical stimulation via a pulse generator transdermally through the glabrous skin surface and to a target nerve or tissue within the hand to stimulate the target nerve or tissue within the hand so that pain felt by the subject is mitigated. The pulses generated during the electrical stimulation therapy may include pulses of two different magnitudes.