-
1.发明公开公开(公告)号：US20240285557A1
公开(公告)日：2024-08-29
申请号：US18572480
申请日：2022-06-24
申请人： INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY , KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
发明人： Kyoung Oh CHO , Tae ll JEON , Sun Woo LEE , Yeong Bin BAEK , Hyung Jun Kwon , Hueng Sik CHOI , Sang lk PARK , Muhammad SHARIF , Jeong Ah LIM
IPC分类号： A61K31/17 , A61K31/215 , A61K31/675 , A61P31/14 , A61P31/16
CPC分类号： A61K31/17 , A61K31/215 , A61K31/675 , A61P31/14 , A61P31/16
摘要： The present invention relates to a therapeutic agent of a lipase inhibitor for a wide spectrum of RNA viral infections in humans and animals. More specifically, the lipase inhibitor can be used as a therapeutic agent for influenza A virus infection, bovine coronavirus infection, porcine epidemic diarrhea coronavirus infection, bovine rotavirus infection, porcine reproductive and respiratory syndrome virus infection, and sapoviral infection and furthermore, can be utilized as a therapeutic agent for various RNA viral infections in humans and animals, such as infections with SARS COV-1, MERS-COV, Zika virus, dengue fever virus, and hepatitis A and C viruses.
-
公开(公告)号：US12070290B2
公开(公告)日：2024-08-27
申请号：US17059597
申请日：2019-03-21
发明人： Chang Sei Kim , Jong Oh Park , Eun Pyo Choi , Byung Jeon Kang , Kim Tien Nguyen , Gwang Jun Go
CPC分类号： A61B34/73 , A61B17/00234 , A61B17/320758 , A61B34/20 , A61B34/30 , A61B2017/00345 , A61B2034/303 , A61B2034/732 , A61B2090/3762 , A61B2090/378 , A61M2025/09183
摘要： The present invention relates to a medical robot system capable of effectively removing a calcified thrombus in a blood vessel. The present invention proposes a new guide-wired helical microrobot for mechanical thrombectomy applied to a calcified thrombus. Also, the present invention proposes an electromagnetic navigation system (ENS) which uses a high frequency operation that is based on a resonant effect in order to enhance the boring force of a microrobot. The microrobot system of the present invention can precisely tunnel through a blood vessel blockage site by means of the electromagnetic navigation system without damaging blood vessel walls. The microrobot system of the present invention has a wide range of applications including not only for thrombosis, but also thromboangiitis obliterans caused by vasoocclusion, cerebral infarction, strokes, angina or myocardial infarction, peripheral artery occlusive disease, or atherosclerosis, etc.
-
公开(公告)号：US20240277837A1
公开(公告)日：2024-08-22
申请号：US18568069
申请日：2022-06-29
发明人： Joon Haeng RHEE , Shee Eun LEE , Koemchhoy KHIM , Sao PUTH
IPC分类号： A61K39/39 , A61K39/00 , A61K39/145 , A61P31/16 , C07K14/28
CPC分类号： A61K39/39 , A61K39/145 , A61P31/16 , C07K14/28 , A61K2039/55516
摘要： The present invention relates to: deimmunized flagellin that does not induce the production of flagellin-specific antibodies; and use thereof. In particular, the present invention relates to a flagellin variant in which a major epitope that forms an antibody against flagellin is deleted, the flagellin variant being characterized by, when used as a vaccine adjuvant, not producing antibodies against flagellin while maintaining an excellent immune enhancer effect.
-
公开(公告)号：US20240218318A1
公开(公告)日：2024-07-04
申请号：US18288862
申请日：2021-04-30
发明人： Hyon El CHOY , Kwangsoo KIM , Jae Ho JEONG , Dae Jin LIM , Taner DUYSAK , Quang Thanh TRAN
IPC分类号： C12N1/20 , A61K39/00 , A61K39/112 , A61K49/00 , A61P35/00 , C07K14/255 , C12N9/12 , C12R1/42
CPC分类号： C12N1/205 , A61K39/0275 , A61K49/0017 , A61P35/00 , C07K14/255 , C12N9/1235 , C12Y207/06005 , A61K2039/522 , C12R2001/42
摘要： The present invention relates to an attenuated Salmonella gallinarum strain and use thereof. Particularly, the present invention relates to: a novel attenuated Salmonella strain in which all of a gene encoding guanosine tetraphosphate (ppGpp) synthetase, a gene that induces the function of a type III secretion system (T3SS)(ssrAB), and a Gifsy 2prophage gene are deleted; and a composition for treating or diagnosing tumors by using same.
-
5.发明公开公开(公告)号：US20240207380A1
公开(公告)日：2024-06-27
申请号：US18555988
申请日：2022-10-26
发明人： Joon Haeng RHEE , Shee Eun LEE , Verma VIVEK , Sao PUTH , Seol Hee HONG
CPC分类号： A61K39/0011 , A61P35/00 , C07K7/08 , A61K2039/55516
摘要： The present invention relates to a novel peptide targeting dendritic cells in the body, and a composition which is for treating cancer, and comprises the peptide. Specifically, the present invention relates to a composition for treating or preventing cancer, the composition comprising: a novel peptide targeting dendritic cells in the body; a tumor antigen; and flagellin. In addition, the novel peptide targeting dendritic cells in the body, the tumor antigen, and the flagellin according to the present invention may be linked by a single peptide or included in respective peptides.
-
6.发明公开公开(公告)号：US20240197788A1
公开(公告)日：2024-06-20
申请号：US18287435
申请日：2022-04-27
IPC分类号： A61K35/30 , A61P25/16 , C12N5/00 , C12N5/0793
CPC分类号： A61K35/30 , A61P25/16 , C12N5/0018 , C12N5/0619
摘要： A pharmaceutical composition utilizes a cultured product obtained by differentiating a mesenchymal stem cell into a neuron. The pharmaceutical composition may be used to treat Parkinson's disease. The cultured product exhibits a preventive or therapeutic effect against Parkinson's disease by inhibiting dopaminergic neuron apoptosis by reducing insoluble alpha-synuclein aggregated in the neuron.
-
公开(公告)号：US20240108664A1
公开(公告)日：2024-04-04
申请号：US17768567
申请日：2020-10-29
发明人： Hyon El CHOY , Jae Ho JEONG , Dae Jin LIM , Hyung Ju LIM , Kwangsoo KIM
IPC分类号： A61K35/74 , A61K49/00 , A61P35/00 , C12N1/20 , C12N1/36 , C12N9/02 , C12N9/12 , C12N9/16 , C12N15/74
CPC分类号： A61K35/74 , A61K49/0097 , A61P35/00 , C12N1/205 , C12N1/36 , C12N9/0008 , C12N9/1235 , C12N9/16 , C12N15/74 , C12Y102/0105 , C12Y207/06005 , C12Y301/07002 , C12R2001/42
摘要： The present invention relates to a tumor-targeting Salmonella gallinarum strain and the use thereof. The tumor-targeting Salmonella gallinarum strain has excellent tumor proliferation inhibitory activity and enables tumor-specific targeting, and thus can be utilized for treatment and imaging of tumors without any side effects.
-
公开(公告)号：US20240017310A1
公开(公告)日：2024-01-18
申请号：US18065810
申请日：2022-12-14
发明人： Chae Hwan Hong , Young Ho Choi , Soo Jin Yeom , Won Seok Chi
CPC分类号： B09B3/60 , C12N1/205 , C12R2001/38
摘要： Disclosed are a composition including a Pseudomonas sp. strain having excellent plastic degradation activity and the use thereof. The Pseudomonas sp. Strain may include Pseudomonas sp. JNU 01 (Accession No: KCTC 14861BP).
-
公开(公告)号：US20230346851A1
公开(公告)日：2023-11-02
申请号：US18002292
申请日：2020-07-08
发明人： Jung Joon Min , Mi Ryung Song , Sung Hwan You , Yeong Jin Hong , Nguyen Dinh Huy
IPC分类号： A61K35/74 , C07K14/24 , C07K14/705 , C07K14/47 , C07K14/71 , A61P35/00 , G01N33/574
CPC分类号： A61K35/74 , C07K14/24 , C07K14/70596 , C07K14/4703 , C07K14/4748 , C07K14/71 , A61P35/00 , G01N33/574 , A61K38/00
摘要： The present invention relates to a Salmonella strain that selectively acts on cancer for the treatment of cancer, and a composition for preventing or treating cancer containing the same. In particular, the Salmonella strain according to the present invention has a tumor-suppressing effect, but has a significantly low viability in normal organs, and thus may have a significant anticancer effect compared to conventional inventions.
-
10.发明公开公开(公告)号：US20230218687A1
公开(公告)日：2023-07-13
申请号：US17927052
申请日：2021-02-01
发明人： Jong Hwan PARK , Dong Yeon KIM
IPC分类号： A61K35/747 , A61P1/00 , A61P29/00
CPC分类号： A61K35/747 , A61P1/00 , A61P29/00
摘要： The present invention relates to a composition for preventing or treating inflammatory diseases, comprising a Lactobacillus sakei CVL-001 strain. The composition activates NOD2, which is an inflammation regulator, and exhibits the effects of inhibiting weight loss and improving clinical activity scores (disease activity index; DAI) in an animal model in which ulcerative colitis is induced, and thus the present invention can be effectively used in the prevention, treatment or alleviation of inflammatory diseases.
-
-
-
-
-
-
-
-
-
搜索结果
331 条记录 (耗时 0.031 秒)
