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    GENERIC INERT BIO-VECTOR SALMONELLA SP. AND POTENTIAL USES THEREOF
    2.
    发明公开
    GENERIC INERT BIO-VECTOR SALMONELLA SP. AND POTENTIAL USES THEREOF 审中-公开

    公开(公告)号：US20230193194A1

    公开(公告)日：2023-06-22

    申请号：US17642238

    申请日：2020-12-28

    申请人： YANGZHOU UNIVERSITY

    发明人： Guoqiang ZHU ,  Bin YANG ,  Yang YANG ,  Xia MENG ,  Pengpeng XIA ,  Qiangde DUAN ,  Xiaofang ZHU

    IPC分类号： C12N1/20 ,  G01N33/569

    CPC分类号： C12N1/205 ,  G01N33/56916 ,  C12R2001/42

    摘要： A generic inert bio-vector Salmonella sp. S9H and potential uses thereof are provided. The generic inert bio-vector Salmonella sp. S9H is derived from a continuous in-vitro culture of an inert bio-vector bacterium Salmonella sp. S9 by using LB solid and liquid culture media for passage to the fortieth generation. With a quantity of bacteria at a working concentration, the S9H does not cause non-specific agglutination reactions in sera or whole blood derived from humans, mice, cattle, pigs and poultry (including chickens, ducks, geese, turkeys, pigeons and quails); moreover, S9H has a property of carrying, and expressing and displaying different antigen factors derived from humans, mice, cattle, pigs and poultry (including chickens, ducks, geese, turkeys, pigeons and quails) on the surface thereof .

    Inert carrier
    3.
    发明授权
    Inert carrier 有权

    公开(公告)号：US12085566B2

    公开(公告)日：2024-09-10

    申请号：US16963079

    申请日：2020-01-13

    申请人： YANGZHOU UNIVERSITY

    发明人： Guoqiang Zhu ,  Bin Yang ,  Pengpeng Xia ,  Qiangde Duan ,  Yang Yang ,  Xia Meng ,  Xiaofang Zhu

    IPC分类号： G01N33/569 ,  C12N1/20 ,  C12R1/42

    CPC分类号： G01N33/56916 ,  C12N1/205 ,  C12R2001/42 ,  G01N2333/255

    摘要： The present invention relates to an inert carrier Salmonella and potential use thereof, which is expected to be developed into a new inert carrier bacteria, and can be applied to the development of an indirect agglutination test method for simple and rapid detection of antigens or infected antibodies. The inert carrier Salmonella has been deposited in CGMCC in Beijing on Mar. 18, 2019 with the accession number of CGMCC No.17340, and is classified as Salmonella sp.with a strain code of S9. The Salmonella has no visible agglutination reaction with various chicken sera derived from different genetic backgrounds, i.e., it has no non-specific agglutination reaction with chicken sera derived from broad range of genetic backgrounds.