Precedent-based ultrasound focusing

    公开(公告)号:US11291430B2

    公开(公告)日:2022-04-05

    申请号:US16314808

    申请日:2017-07-14

    申请人: INSIGHTEC, LTD.

    摘要: Various approaches for operating an ultrasound transducer having multiple transducer elements include acquiring one or more measurements of anatomical regions through which ultrasound waves emitted from the transducer elements travel; for each of the anatomical regions, determining values of characteristics based at least in part on the measurement(s); computationally predicting aberrations of the ultrasound waves traveling through the anatomical regions by using the first values as input to a predictor that has been computationally trained to predict ultrasound aberrations based on values of the characteristics; and driving the transducer elements to compensate for the predicted aberrations.

    Systems and methods for ensuring coherence between multiple ultrasound transducer arrays

    公开(公告)号:US11272842B2

    公开(公告)日:2022-03-15

    申请号:US16314092

    申请日:2017-06-20

    申请人: INSIGHTEC, LTD.

    发明人: Yoav Levy

    摘要: A system for maintaining coherence of ultrasound waves emitted by multiple transducer arrays includes multiple retention arms, each for receiving one of the transducer arrays; a connecting frame for receiving and mechanically retaining the arms in fixed angular relation to each other; and a processor configured to determine relative locations of the transducer arrays with respect to one another and the connecting frame; determine a location of the connecting frame relative to an anatomic region of interest; determine a spatial arrangement of the transducer elements in each transducer array with respect to the anatomic region of interest; and adjust a transmission configuration of the transducer elements in the transducer arrays to achieve a desired focusing property with respect to the anatomic region of interest while maintaining coherence therebetween.

    ADAPTIVE, CLOSED-LOOP ULTRASOUND THERAPY

    公开(公告)号:US20210170204A1

    公开(公告)日:2021-06-10

    申请号:US16771768

    申请日:2018-12-05

    申请人: INSIGHTEC, LTD.

    IPC分类号: A61N7/00

    摘要: Various approaches to focusing an ultrasound transducer includes causing the ultrasound transducer to transmit ultrasound waves to the target region; causing the detection system to indirectly measure the focusing properties; and based at least in part on the indirectly measured focusing properties, adjusting a parameter value associated with at least one of the transducer elements so as to achieve a target treatment power at the target region.

    Phased array calibration for geometry and aberration correction

    公开(公告)号:US10739316B2

    公开(公告)日:2020-08-11

    申请号:US15837392

    申请日:2017-12-11

    申请人: Oleg Prus Yoav Levy

    发明人: Oleg Prus Yoav Levy

    摘要: Various approaches for calibrating the geometry of an ultrasound transducer having multiple transducer elements include providing an acoustic reflector spanning an area traversing by multiple beam paths of ultrasound waves transmitted from all (or at least some) transducer elements to a focal zone; causing the transducer elements to transmit the ultrasound waves to the focal zone; measuring reflections of the ultrasound waves off the acoustic reflector; and based at least in part on the measured reflections, determining optimal geometric parameters associated with the transducer elements.

    Cavitation localization
    5.
    发明授权

    公开(公告)号:US10575816B2

    公开(公告)日:2020-03-03

    申请号:US15415351

    申请日:2017-01-25

    申请人: Oleg Prus Yoav Levy

    发明人: Oleg Prus Yoav Levy

    IPC分类号: A61B8/08 A61B8/00 A61B8/14

    摘要: Various approaches for detecting microbubble cavitation resulting from ultrasound waves transmitted from an ultrasound transducer include associating at least one time-domain reference signal with microbubble cavitation; causing the transducer to transmit one or more ultrasound pulse; acquiring, in the time domain, an echo signal from microbubbles in response to the transmitted ultrasound pulse(s); correlating at least a portion of the echo signal to at least a corresponding portion of the time-domain reference signal based on similarity therebetween; and detecting the microbubble cavitation based on the corresponding portion of the reference signal.

    Controlled, non-linear focused ultrasound treatment

    公开(公告)号:US10130828B2

    公开(公告)日:2018-11-20

    申请号:US11993443

    申请日:2006-06-19

    摘要: A system (10) for treating tissue within a body is configured to deliver a first level of ultrasound energy to a target tissue region (42) for a first duration resulting in the generation of micro-bubbles (56) in the target tissue region, determine one or more characteristics of the target tissue region in the presence of the micro-bubbles, and deliver a second level of ultrasound energy to the target tissue region for a second duration, wherein one or both of the second energy level and the second duration are based, at least in part, on the determined one or more characteristics of the target tissue region.

    Acoustic beam forming in phased arrays including large numbers of transducer elements
    8.
    发明授权
    Acoustic beam forming in phased arrays including large numbers of transducer elements 有权
    在包括大量换能器元件的相控阵列中形成声束

    公开(公告)号:US08002706B2

    公开(公告)日:2011-08-23

    申请号:US12559939

    申请日:2009-09-15

    IPC分类号: A61B8/00

    摘要: A focused ultrasound system includes a transducer array, a controller for providing drive signals to the transducer array, and a switch. The transducer array includes a plurality of “n” transducer elements, and the controller includes a plurality of “m” output channels providing sets of drive signals having respective phase shift values, “m” being less than “n.” The switch is coupled to the output channels of the controller and to the transducer elements, and is configured for connecting the output channels to respective transducer elements. The controller may assign the transducer elements to respective output channels based upon a size and/or shape of a desired focal zone within the target region, to steer or otherwise move a location of the focal zone, and/or to compensate for tissue aberrations caused by tissue between the transducer array and the focal zone, geometric tolerances and/or impedance variations of the transducer elements.

    摘要翻译: 聚焦超声系统包括换能器阵列,用于向换能器阵列提供驱动信号的控制器和开关。 换能器阵列包括多个“n”个换能器元件,并且控制器包括多个“m”个输出通道,提供具有各自的相移值的驱动信号组,“m”小于“n”。开关被耦合 到控制器和换能器元件的输出通道,并且被配置为将输出通道连接到相应的换能器元件。 控制器可以基于目标区域内的期望焦点区域的尺寸和/或形状来将换能器元件分配到相应的输出通道,以引导或以其他方式移动聚焦区域的位置,和/或补偿由此产生的组织像差 通过换能器阵列和焦点区域之间的组织,换能器元件的几何公差和/或阻抗变化。

    CONTROLLED, NON-LINEAR FOCUSED ULTRASOUND TREATMENT
    9.
    发明申请
    CONTROLLED, NON-LINEAR FOCUSED ULTRASOUND TREATMENT 审中-公开
    控制,非线性聚焦超声治疗

    公开(公告)号:US20100241036A1

    公开(公告)日:2010-09-23

    申请号:US11993443

    申请日:2006-06-19

    IPC分类号: A61N7/02

    摘要: A system (10) for treating tissue within a body is configured to deliver a first level of ultrasound energy to a target tissue region (42) for a first duration resulting in the generation of micro-bubbles (56) in the target tissue region, determine one or more characteristics of the target tissue region in the presence of the micro-bubbles, and deliver a second level of ultrasound energy to the target tissue region for a second duration, wherein one or both of the second energy level and the second duration are based, at least in part, on the determined one or more characteristics of the target tissue region.

    摘要翻译: 用于治疗身体内的组织的系统(10)被配置为将第一级超声能量传递到目标组织区域(42)持续第一持续时间,从而在目标组织区域中产生微气泡(56) 在存在微气泡的情况下确定目标组织区域的一个或多个特征,并且将第二水平的超声能量传递到目标组织区域持续第二持续时间,其中第二能量水平和第二持续时间 至少部分地基于所确定的目标组织区域的一个或多个特征。

    MOTION COMPENSATED IMAGE-GUIDED FOCUSED ULTRASOUND THERAPY SYSTEM
    10.
    发明申请
    MOTION COMPENSATED IMAGE-GUIDED FOCUSED ULTRASOUND THERAPY SYSTEM 有权
    运动补偿图像引导超声波治疗系统

    公开(公告)号:US20090088623A1

    公开(公告)日:2009-04-02

    申请号:US11865662

    申请日:2007-10-01

    IPC分类号: A61B5/055 A61N7/02

    摘要: An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.

    摘要翻译: 图像引导治疗系统包括被配置为传送治疗能量束的热处理装置(例如,超声换能器),并且该系统还包括被配置用于获取图像的成像装置(例如,磁共振成像(MRI)装置) 的靶组织块和热处理装置。 该系统还包括控制器,其被配置为控制热处理装置的热剂量特性以将能量束聚焦在位于患者的内部身体区域中的目标组织块上;以及处理器,被配置为跟踪热处理装置 以及基于所获取的图像的公共坐标系中的目标组织质量。 系统可以可选地包括被配置为显示所获取的图像的显示器。