Diagnosis method using laser induced breakdown spectroscopy and diagnosis device performing the same

    公开(公告)号:US11079279B2

    公开(公告)日:2021-08-03

    申请号:US16863140

    申请日:2020-04-30

    申请人: SPECLIPSE, Inc.

    摘要: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic method may include projecting a pulsed laser to a suspicious specimen, obtaining first spectrum data on the light collected from the suspicious specimen, projecting the pulsed laser to a non-diseased specimen, obtaining second spectrum data on the light collected from the non-diseased specimen, and determining whether a disease is present in the suspicious specimen from a comparison value of the first spectrum data and the second spectrum data using an artificial neural network.

    Laser-Based System And Method For Diagnosing Pigmented Lesions

    公开(公告)号:US20180206780A1

    公开(公告)日:2018-07-26

    申请号:US15895509

    申请日:2018-02-13

    申请人: SPECLIPSE, INC.

    IPC分类号: A61B5/00

    摘要: According to one embodiment of the present disclosure, a device for diagnosing a pigmented lesion includes: a sound detector configured to detect a photoacoustic wave generated when a laser is irradiated onto a target from which a pigmented lesion is to be identified; and a diagnosis unit configured to calculate a depth and/or thickness of the pigmented lesion, based on a time at which the photoacoustic wave is detected, and laser irradiation time information on the laser irradiated onto the target.

    DIAGNOSIS METHOD USING LASER INDUCED BREAKDOWN SPECTROSCOPY AND DIAGNOSIS DEVICE PERFORMING THE SAME

    公开(公告)号:US20210140825A1

    公开(公告)日:2021-05-13

    申请号:US17135675

    申请日:2020-12-28

    申请人: SPECLIPSE, Inc.

    IPC分类号: G01J3/443

    摘要: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

    NON-DISCRETE SPECTRAL ANALYSIS ALGORITHMS AND METHODS FOR IN VIVO DETECTION OF TISSUE MALIGNANCY BASED ON LASER SPECTROSCOPY

    公开(公告)号:US20190246971A1

    公开(公告)日:2019-08-15

    申请号:US16043689

    申请日:2018-07-24

    申请人: Speclipse, Inc.

    IPC分类号: A61B5/00

    摘要: According to an embodiment of the present disclosure, a non-transitory computer readable storage medium which stores one or more non-discrete spectrum analysis programs for lesion tissue detection based on laser spectroscopy is provided. The one or more programs cause an electronic device provided with one or more processors to execute a lesion tissue detection method, and the lesion tissue detection method includes a step of determining whether there is lesion tissue by applying a lesion tissue detection learning model to a result of non-discrete spectrum measurement. The result of the non-discrete spectrum measurement is a result of measuring spectra of all generated light that is generated from a time when a laser is projected onto a sample until the generated light is no longer generated.

    LASER DEVICE AND LASER OUTPUT CONTROL METHOD THEREIN

    公开(公告)号:US20190015681A1

    公开(公告)日:2019-01-17

    申请号:US15948545

    申请日:2018-04-09

    申请人: Speclipse, Inc.

    IPC分类号: A61N5/06

    摘要: The present disclosure relates to a method and a device for controlling a laser output. According to an embodiment, there are provided a method for controlling a laser output of a laser device, provided with a laser generator and a handpiece for radiating a laser generated at the laser generator onto a target, and a device performing the method. The method includes the steps of: measuring, by a plurality of distance sensors arranged along a circumference of one end of the handpiece from which the laser is outputted, distances between the plurality of distance sensors and the target; based on the distances between the distance sensors and the target, calculating an effective area which is a region of the target onto which the laser is really radiated; and increasing or reducing the laser output to radiate the laser onto the effective area with a predetermined energy density.