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1.
公开(公告)号:US11079279B2
公开(公告)日:2021-08-03
申请号:US16863140
申请日:2020-04-30
申请人: SPECLIPSE, Inc.
发明人: Sung Hyun Pyun , Wan Ki Min
摘要: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic method may include projecting a pulsed laser to a suspicious specimen, obtaining first spectrum data on the light collected from the suspicious specimen, projecting the pulsed laser to a non-diseased specimen, obtaining second spectrum data on the light collected from the non-diseased specimen, and determining whether a disease is present in the suspicious specimen from a comparison value of the first spectrum data and the second spectrum data using an artificial neural network.
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2.
公开(公告)号:US20190053711A1
公开(公告)日:2019-02-21
申请号:US16161335
申请日:2018-10-16
申请人: SPECLIPSE, INC.
发明人: Sung Hyun PYUN , Wan Ki MIN
摘要: According to an embodiment, a tip for a diagnosis laser handpiece, coupled to a handpiece and used therein includes: a light emission module configured to emit a laser to a target; and a light adjustment module disposed on a path through which the laser emitted to the target travels. The light adjustment module is configured to adjust energy of the laser emitted to the target, and a focus size of the laser.
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公开(公告)号:US20180206780A1
公开(公告)日:2018-07-26
申请号:US15895509
申请日:2018-02-13
申请人: SPECLIPSE, INC.
发明人: Sung Hyun PYUN , Wan Ki MIN
IPC分类号: A61B5/00
CPC分类号: A61B5/444 , A61B5/0095 , A61B5/7435 , A61N5/0616
摘要: According to one embodiment of the present disclosure, a device for diagnosing a pigmented lesion includes: a sound detector configured to detect a photoacoustic wave generated when a laser is irradiated onto a target from which a pigmented lesion is to be identified; and a diagnosis unit configured to calculate a depth and/or thickness of the pigmented lesion, based on a time at which the photoacoustic wave is detected, and laser irradiation time information on the laser irradiated onto the target.
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公开(公告)号:US11672425B2
公开(公告)日:2023-06-13
申请号:US16101928
申请日:2018-08-13
申请人: Speclipse, Inc.
发明人: Sung Hyun Pyun , Wanki Min
CPC分类号: A61B5/0084 , A61B5/0013 , A61B5/0071 , A61B5/0075 , A61B5/414 , A61B5/441 , A61B5/444 , A61B5/4836 , A61B5/726 , G01J3/0218 , G01J3/443 , G01N21/718 , G16H50/20 , A61B2560/0233
摘要: According to an embodiment of the present disclosure, there is provided a laser spectroscopy-based independent device, including: a spectrometer configured to measure a spectrum of generated light which is generated by a laser projected onto a sample; and a disease analysis module configured to determine whether there is lesion tissue by applying a lesion tissue detection learning model to a result of non-discrete spectrum measurement, which is measured by the spectrometer, wherein the spectrometer is configured to measure spectra of all generated light that is generated from a time when the laser is projected onto the sample.
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5.
公开(公告)号:US20210140825A1
公开(公告)日:2021-05-13
申请号:US17135675
申请日:2020-12-28
申请人: SPECLIPSE, Inc.
发明人: Sung Hyun PYUN , Wan Ki MIN
IPC分类号: G01J3/443
摘要: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.
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6.
公开(公告)号:US20180146858A1
公开(公告)日:2018-05-31
申请号:US15877722
申请日:2018-01-23
申请人: Speclipse, Inc.
发明人: Sung Hyun PYUN , Wanki MIN
CPC分类号: A61B5/0077 , A61B5/0075 , A61B5/441 , A61B5/7246 , A61B5/7282 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/024 , G01J3/0248 , G01J3/0291 , G01J3/2803 , G01J3/2823 , G01J3/443 , G01J2003/282
摘要: A disease diagnosis and skin age measurement apparatus includes: a first light collection unit; a second light collection unit; a spectrometer configured to measure a spectrum of the light which is collected by the second light collection unit; a spectrum data comparison unit for disease diagnosis configured to compare the spectrum measured by the spectrometer and reference spectrum data for disease diagnosis; a CCD; an image data comparison unit configured to compare the digital image converted by the CCD and a reference image; a disease diagnosis unit configured to determine whether there is a disease in the body tissue; and/or a spectrum data comparison unit for skin age measurement configured to measure skin age by comparing a spectrum measured by the spectrometer and reference spectrum data for skin age measurement, wherein the light projected onto the body tissue is collimate light.
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公开(公告)号:US09907472B2
公开(公告)日:2018-03-06
申请号:US15258253
申请日:2016-09-07
申请人: Speclipse, Inc.
发明人: Sung Hyun Pyun , Wanki Min
CPC分类号: A61B5/0077 , A61B5/0075 , A61B5/441 , A61B5/7246 , A61B5/7282 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/024 , G01J3/0248 , G01J3/0291 , G01J3/2803 , G01J3/2823 , G01J3/443 , G01J2003/282 , G06F19/00
摘要: A disease diagnosis and skin age measurement apparatus includes: a first light collection unit; a second light collection unit; a spectrometer configured to measure a spectrum of the light which is collected by the second light collection unit; a spectrum data comparison unit for disease diagnosis configured to compare the spectrum measured by the spectrometer and reference spectrum data for disease diagnosis; a CCD; an image data comparison unit configured to compare the digital image converted by the CCD and a reference image; a disease diagnosis unit configured to determine whether there is a disease in the body tissue; and/or a spectrum data comparison unit for skin age measurement configured to measure skin age by comparing a spectrum measured by the spectrometer and reference spectrum data for skin age measurement, wherein the light projected onto the body tissue is collimate light.
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8.
公开(公告)号:US11892353B2
公开(公告)日:2024-02-06
申请号:US17883724
申请日:2022-08-09
申请人: SPECLIPSE, INC.
发明人: Sung Hyun Pyun , Wan Ki Min
IPC分类号: G01J3/30 , G01J3/443 , B63B25/16 , B63J2/14 , F02M21/02 , F17C6/00 , F17C9/02 , F17C9/04 , G01J3/42 , G01N21/71
CPC分类号: G01J3/443 , B63B25/16 , B63J2/14 , F02M21/0215 , F17C6/00 , F17C9/02 , F17C9/04 , F17C2221/033 , F17C2227/0164 , F17C2227/0185 , F17C2227/0339 , F17C2227/0348 , F17C2227/0358 , F17C2265/033 , F17C2265/034 , F17C2265/037 , F17C2265/038 , F17C2265/066 , F17C2270/0105 , G01J2003/423 , G01N21/718
摘要: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.
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9.
公开(公告)号:US20190246971A1
公开(公告)日:2019-08-15
申请号:US16043689
申请日:2018-07-24
申请人: Speclipse, Inc.
发明人: Sung Hyun PYUN , Wanki MIN
IPC分类号: A61B5/00
CPC分类号: A61B5/444 , A61B5/0075 , A61B5/7267
摘要: According to an embodiment of the present disclosure, a non-transitory computer readable storage medium which stores one or more non-discrete spectrum analysis programs for lesion tissue detection based on laser spectroscopy is provided. The one or more programs cause an electronic device provided with one or more processors to execute a lesion tissue detection method, and the lesion tissue detection method includes a step of determining whether there is lesion tissue by applying a lesion tissue detection learning model to a result of non-discrete spectrum measurement. The result of the non-discrete spectrum measurement is a result of measuring spectra of all generated light that is generated from a time when a laser is projected onto a sample until the generated light is no longer generated.
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公开(公告)号:US20190015681A1
公开(公告)日:2019-01-17
申请号:US15948545
申请日:2018-04-09
申请人: Speclipse, Inc.
发明人: Sung Hyun PYUN , Wanki MIN , Hyoung Soo SHIN
IPC分类号: A61N5/06
摘要: The present disclosure relates to a method and a device for controlling a laser output. According to an embodiment, there are provided a method for controlling a laser output of a laser device, provided with a laser generator and a handpiece for radiating a laser generated at the laser generator onto a target, and a device performing the method. The method includes the steps of: measuring, by a plurality of distance sensors arranged along a circumference of one end of the handpiece from which the laser is outputted, distances between the plurality of distance sensors and the target; based on the distances between the distance sensors and the target, calculating an effective area which is a region of the target onto which the laser is really radiated; and increasing or reducing the laser output to radiate the laser onto the effective area with a predetermined energy density.
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