Inhalation device
    8.
    发明授权
    Inhalation device 失效
    吸入装置

    公开(公告)号:US3795244A

    公开(公告)日:1974-03-05

    申请号:US3795244D

    申请日:1973-02-02

    申请人: SYNTEX CORP

    发明人: LAX R HERD A

    IPC分类号: A61M15/00 A61M15/06

    摘要: An inhalation device having means to engage the free end of a powdered medicament-holding capsule as the capsule is pierced to provide outlet ports for the powdered medicament held therein. Such engagement ensures that the capsule is completely seated in the rotary member on which it is supported and thus ensures that the outlet ports are positioned at the desired locations adjacent the shoulder of the capsule. Additionally, such engagement enables the piercing operation to be conducted in any orientation of the inhalation device. The rotary member, which supports the capsule during inhalation, is itself supported by a shaft having a polygon shaped base having n sides. The rotary member has a hollow sleeve which fits over the shaft, the sleeve having a polygon shaped inner surface having at least n + 1 sides. During inhalation which causes the rotary member to spin about the supporting shaft, contact of the adjacent polygon shaped surfaces with each other positively causes the walls of the capsule to undergo repeated changes or radial acceleration whereby the powdered medicament is dispersed from the capsule.

    摘要翻译: 一种吸入装置,其具有在胶囊被刺穿时接合粉末状药物保持胶囊的自由端的装置,以提供保持在其中的粉末状药物的出口。 这种接合确保胶囊完全就位于其所支撑的旋转构件中,从而确保出口端口位于邻近胶囊肩部的所需位置。 此外,这种接合使得能够在吸入装置的任何取向上进行刺穿操作。 在吸入期间支撑胶囊的旋转部件本身由具有n个侧面的多边形基部的轴支撑。 旋转构件具有装配在轴上的中空套筒,套筒具有至少n + 1个侧面的多边形形状的内表面。 在使旋转构件围绕支撑轴旋转的吸入期间,相邻的多边形形状的表面彼此接触积极地导致胶囊的壁经历反复的变化或径向加速,由此粉末状药物从胶囊中分散。

    Microbiological reduction of 1,3,-dioxo-2-alkylcycloalkanes
    9.
    发明授权
    Microbiological reduction of 1,3,-dioxo-2-alkylcycloalkanes 失效
    1,3-二氧代-2-烷基胆碱的微生物降解

    公开(公告)号:US3793148A

    公开(公告)日:1974-02-19

    申请号:US3793148D

    申请日:1972-07-24

    申请人: SYNTEX CORP

    发明人: LANZILOTTA R

    IPC分类号: C12P7/26 C12P7/38 C12B1/00

    摘要: An improved method of microbiologically reducing a 1,3-dioxo-2alkylcycloalkane using members of a group of compounds which increase the production of the 1 Beta -hydroxy-2 Beta -alkyl-3oxocycloalkane product. The products are useful as intermediates in the total synthesis of useful steroid compounds. Alkyl alcohol and acrylonitrile are illustrated as representative of the useful group of compounds.

    摘要翻译: 使用增加1β-羟基-2β-烷基-3-氧代环烷烃产物产生的一组化合物的成员来微生物还原1,3-二氧代-2-烷基环烷烃的改进方法。 该产品可用作有用类固醇化合物的全合成中的中间体。 示出了烷基醇和丙烯腈作为有用的化合物组的代表。

    Implanter having an improved cartridge ejector
    10.
    发明授权
    Implanter having an improved cartridge ejector 失效
    具有改进的盒式喷枪的植绒

    公开(公告)号:US3744493A

    公开(公告)日:1973-07-10

    申请号:US3744493D

    申请日:1972-01-10

    申请人: SYNTEX CORP

    发明人: BOOHER K VAN LOOZEN G

    IPC分类号: A61M37/00 A61D7/00 A61M5/00

    CPC分类号: A61M37/0069

    摘要: A pellet implanter includes a tubular body having a movable plunger therein extending from the rear end thereof through a hollow needle at the forward end thereof for pushing pellets from a pellet cartridge through the cartridge and through the hollow needle into the animal being treated. A side breech opening is provided in the body of the implanter. A cartridge ejector and stripper is provided proximate the rear end of the breech opening. The cartridge stripper and ejector includes a plug having a central bore for retaining the plunger therein against transverse translation. A forwardly projecting eccentric end portion of the ejector and stripper plug engages the rearwardly moving cartridge for stripping the cartridge from the plunger and for flipping the spent cartridge through the side breech opening, thereby ejecting same.