摘要:
2-(2''-Naphthyl) acetaldehyde derivatives optionally substituted at the 2 position and/or positions C-1'', 4'', 5'', 7'' or 8''; and/or position C-6'' or positions C-5'' and 7'' exhibit anti-inflammatory, analgesic, antipyretic and anti-pruritic activity.
摘要:
2-(2''-Naphthyl) acetaldehyde derivatives optionally substituted at the 2 position and/or positions C-1'', 4'',5'',7'' or 8''; and/or position C-6'' or positions C-5'' and 7'' exhibit anti-inflammatory, analgesic, antipyretic and anti-pruritic activity.
摘要:
New compounds of the 1,2,3,4,9,12-hexahydrophenanthrene class, useful as estrogenic and anti-fertility agents, and methods for their preparation. 1 Alpha -Ethyl-2 Alpha -carboxy-2 Beta methyl-7-methoxy-1,2,3,4,9,12-hexahydrophenanthrene is exemplified as illustrative of the class.
摘要:
Preparation of Alpha , Beta -unsaturated carbocyclic ketones by reacting a methylene phosphonium ylid or a mono-substituted methylene phosphonium ylid with an enol lactone.
摘要:
Preparation of Alpha , Beta -unsaturated carbocyclic ketones by reacting an enol lactone with a carbanion generated by treatment of a methylphosphonate or a mono-substituted methylphosphonate with base.
摘要:
2-(2''-Napthyl) acetaldehyde derivatives optionally substituted at the 2 position and/or positions C-1'',4'',5'',7'' or 8''; and/or position C-6'' or positions C-5'' and 7'' exhibit anti-inflammatory, analgesic, antipyretic and anti-pruritic activity.
摘要:
2- (6 - METHOXY -2 - NAPHTHYL)PROPIONIC ACID IS PREPARED BY TREATING 6-METHOXY-2-(1-PROPYNYL) NAPHTHALENE WITH A THALLIC SALT, SUCH AS THALLIUM TRINITRATE, AND A LOWER ALKANOL TO YIELD THE CORRESPONDING ESTER OF 2-(6-METHOXY2-NAPHTHYL)PROPINOIC ACID WHICH IS HYDROLYZED TO THE DESIRED PROPIONIC ACID COMPOUND. THE COMPOUND IS, PREFERABLY, RESOLVED TO YIELD THE BIOLOGICALLY ACTIVE D ISOMER, THE PRODUCT HAS ANTI-INFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIVITIES.
摘要:
An inhalation device having means to engage the free end of a powdered medicament-holding capsule as the capsule is pierced to provide outlet ports for the powdered medicament held therein. Such engagement ensures that the capsule is completely seated in the rotary member on which it is supported and thus ensures that the outlet ports are positioned at the desired locations adjacent the shoulder of the capsule. Additionally, such engagement enables the piercing operation to be conducted in any orientation of the inhalation device. The rotary member, which supports the capsule during inhalation, is itself supported by a shaft having a polygon shaped base having n sides. The rotary member has a hollow sleeve which fits over the shaft, the sleeve having a polygon shaped inner surface having at least n + 1 sides. During inhalation which causes the rotary member to spin about the supporting shaft, contact of the adjacent polygon shaped surfaces with each other positively causes the walls of the capsule to undergo repeated changes or radial acceleration whereby the powdered medicament is dispersed from the capsule.
摘要:
An improved method of microbiologically reducing a 1,3-dioxo-2alkylcycloalkane using members of a group of compounds which increase the production of the 1 Beta -hydroxy-2 Beta -alkyl-3oxocycloalkane product. The products are useful as intermediates in the total synthesis of useful steroid compounds. Alkyl alcohol and acrylonitrile are illustrated as representative of the useful group of compounds.
摘要:
A pellet implanter includes a tubular body having a movable plunger therein extending from the rear end thereof through a hollow needle at the forward end thereof for pushing pellets from a pellet cartridge through the cartridge and through the hollow needle into the animal being treated. A side breech opening is provided in the body of the implanter. A cartridge ejector and stripper is provided proximate the rear end of the breech opening. The cartridge stripper and ejector includes a plug having a central bore for retaining the plunger therein against transverse translation. A forwardly projecting eccentric end portion of the ejector and stripper plug engages the rearwardly moving cartridge for stripping the cartridge from the plunger and for flipping the spent cartridge through the side breech opening, thereby ejecting same.