公开(公告)号：US08528566B2

公开(公告)日：2013-09-10

申请号：US13189723

申请日：2011-07-25

申请人： Frieder Loesel ,  Mathias Glasmacher ,  Ulrich von Pape

发明人： Frieder Loesel ,  Mathias Glasmacher ,  Ulrich von Pape

IPC分类号： A61B19/00 ,  A61B18/20

CPC分类号： A61F9/008 ,  A61B5/0066 ,  A61F9/00825 ,  A61F2009/00844 ,  A61F2009/00851 ,  A61F2009/00872

摘要： A method for ocular surgery requires use of a delivery system for generating and guiding a surgical laser beam to a focal point in a treatment area of an eye. Additionally, a contact device is employed for using the eye to establish a reference datum. Further, an optical detector is coupled to the beam path of the surgical laser to create a sequence of cross-sectional images. Each image visualizes both the reference datum and the focal point. Operationally, a computer then uses these images to position and move the focal point in the treatment area relative to the reference datum for surgery.

摘要翻译： 用于眼部手术的方法需要使用用于产生和引导手术激光束到眼睛的治疗区域中的焦点的递送系统。 此外，使用接触装置来使用眼睛建立参考基准。 此外，光学检测器耦合到手术激光的光束路径以产生一系列横截面图像。 每个图像可以同时显示参考基准和焦点。 在操作上，计算机然后使用这些图像来相对于用于手术的参考基准定位和移动治疗区域中的焦点。

公开(公告)号：US07987077B2

公开(公告)日：2011-07-26

申请号：US12029314

申请日：2008-02-11

申请人： Josef F. Bille

发明人： Josef F. Bille

IPC分类号： G06F9/455

CPC分类号： G06F19/3481 ,  G06F19/00 ,  G16H50/50

摘要： A system and method are provided for simulating a Laser Induced Optical Breakdown (LIOB) protocol to establish a surgical LIOB treatment for a patient. In the system, a library of finite element models characterizing various visual defects in corneas are programmed into a computer. Further, a library of nomograms indicating specific LIOB protocols for correcting respective visual defects are programmed into the computer. As a result, a model and a corresponding nomogram may be selected in view of a patient's diagnostic information. Further, the selected model may be individualized with the diagnostic information to more precisely characterize the patient's visual defects. Thereafter, the computer simulates the indicated LIOB protocol on the individualized model in order to achieve a desired corneal configuration. When the desired corneal configuration is achieved, the final treatment plan may be determined.

摘要翻译： 提供了一种用于模拟激光诱导光学分解（LIOB）协议以建立患者的手术LIOB治疗的系统和方法。 在系统中，将表征角膜各种视觉缺陷的有限元模型库编程到计算机中。 此外，将表示用于校正各种视觉缺陷的特定LIOB协议的列线图的库编程到计算机中。 因此，可以根据患者的诊断信息选择模型和相应的诺模图。 此外，所选择的模型可以用诊断信息来个性化，以更精确地表征患者的视觉缺陷。 此后，计算机模拟指定的LIOB协议在个性化模型上，以实现期望的角膜配置。 当达到所需的角膜构造时，可以确定最终治疗计划。

公开(公告)号：US07780689B2

公开(公告)日：2010-08-24

申请号：US10807420

申请日：2004-03-23

申请人： Craig A. Barrile-Josephson ,  Michael H. Dobner ,  James Kirch ,  Peter J. Halecki ,  Christopher Wagner

发明人： Craig A. Barrile-Josephson ,  Michael H. Dobner ,  James Kirch ,  Peter J. Halecki ,  Christopher Wagner

IPC分类号： A61F9/00

CPC分类号： A61F9/013

摘要： A microkeratome 10 for use in ophthalmic surgery includes a bar-link drive 20 connected to a cutting-head 36. A fixation ring 34 attaches to a patient's eye and is coupled to the bar-link drive 20 to the drive the cutting-head 36 at least partially across the fixation ring 34.

摘要翻译： 用于眼科手术的微型角膜刀10包括连接到切割头36的杆连杆驱动器20.固定环34附接到患者的眼睛并且连接到杆连杆驱动器20以驱动切割头36 至少部分地穿过固定环34。

公开(公告)号：US07717905B2

公开(公告)日：2010-05-18

申请号：US10978613

申请日：2004-11-01

申请人： Frieder Loesel ,  Tobias Kuhn

发明人： Frieder Loesel ,  Tobias Kuhn

IPC分类号： A61F9/008

CPC分类号： A61F9/008 ,  A61F9/00825 ,  A61F2009/00872 ,  A61F2009/00897

摘要： A system and method for performing laser induced optical breakdown (LIOB) in corneal tissue of an eye requires calculating a pattern of focal spots. LIOB is then induced at a first focal spot, and is continued at a plurality of interim focal spots within a time period τ. Each focal spot has a diameter “d1” and generates a temporal cavitation bubble of diameter “d2”. It then collapses within time “τ” to a substantially stationary diameter “d3”, with (d1≦d3≦d2). Importantly, each focal spot is located more than “d2” from every other interim focal spot within the time period of “τ”. At the time “τ”, a second focal spot in the pattern can be generated at a distance “d3” from the first focal spot. This process is then continued with another plurality of interim focal spots being generated within another time period “τ”.

摘要翻译： 用于在眼睛的角膜组织中进行激光诱导光学击穿（LIOB）的系统和方法需要计算焦点的图案。 然后在第一焦点处诱导LIOB，并且在时间段τ内在多个临时焦斑处继续。 每个焦斑具有直径“d1”，并产生直径“d2”的时间空化气泡。 然后在时间“τ”内崩溃到基本上静止的直径“d3”，其中（d1＆nlE; d3＆nlE; d2）。 重要的是，在“τ”的时间段内，每个焦斑位于距离每个其他中间焦点的“d2”以上。 在时间“τ”，可以在与第一焦点相距“d3”的距离处产生图案中的第二焦点。 然后继续在另一个时间段“τ”内产生另外多个临时焦斑的过程。

公开(公告)号：US20240108508A1

公开(公告)日：2024-04-04

申请号：US18532559

申请日：2023-12-07

申请人： TECHNOLAS PERFECT VISION GMBH

发明人： Wolfgang KÜGEL ,  Christof DONITZKY

IPC分类号： A61F9/008 ,  A61F9/009

CPC分类号： A61F9/00836 ,  A61F9/009 ,  A61F2009/00872

摘要： The present disclosure relates to an eye treatment system for performing laser surgery on an eye which includes a laser optical system. The laser optical system includes a scanning system for scanning a focus of a laser beam of the laser light within a cornea of the eye in three dimensions. The laser optical system further includes a focusing optical system. The scanning system is in the beam path of the laser beam between the laser source and the focusing optical system. The eye treatment system further includes a contact element which is in the beam path of the laser beam between the focusing optical system and the eye. The contact element has a contact surface for contacting a cornea of the eye. At least a portion of the contact surface has a shape, which is convex toward the cornea.

公开(公告)号：US10434012B2

公开(公告)日：2019-10-08

申请号：US15874773

申请日：2018-01-18

申请人： BAUSCH & LOMB INCORPORATED ,  TECHNOLAS PERFECT VISION GMBH

发明人： David Haydn Mordaunt ,  Frieder Loesel ,  Gwillem Mosedale

IPC分类号： G06K9/00 ,  A61F9/008 ,  A61F2/16

摘要： A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.

公开(公告)号：US09393155B2

公开(公告)日：2016-07-19

申请号：US13338872

申请日：2011-12-28

申请人： Gerhard Youssefi

发明人： Gerhard Youssefi

IPC分类号： A61N5/06 ,  A61F9/008

CPC分类号： A61F9/00825 ,  A61F2009/00851 ,  A61F2009/0087 ,  A61F2009/00887

摘要： In accordance with the present invention, a system and method are provided for controlling postoperative shrinkage of the capsular bag, after the lens has been removed from the capsular bag. The purpose is to establish a proper optical alignment for a prosthetic Intraocular Lens (IOL). Included in the system are a laser unit for generating a laser beam, a detector for creating an image of the prosthetic IOL in the capsular bag, and a computer for evaluating the image to determine an alignment difference between the IOL axis and a defined axis of the eye. The computer is also used for guiding the laser beam to alter selected tissue in the eye, to thereby influence postoperative shrinkage of the capsular bag and minimize any potential alignment difference between the IOL axis and the defined axis of the eye during capsular bag shrinkage.

摘要翻译： 根据本发明，提供了一种系统和方法，用于控制在从胶囊袋中取出镜片之后胶囊袋的术后收缩。 目的是为假眼内镜（IOL）建立适当的光学对准。 系统中包括用于产生激光束的激光单元，用于在囊袋中产生假体IOL的图像的检测器，以及用于评估图像的计算机，以确定IOL轴和所定义的轴的定义轴线之间的对准差 眼。 计算机还用于引导激光束改变眼睛中的选定组织，从而影响囊袋的术后收缩，并且使囊袋收缩期间IOL轴与眼睛的限定轴线之间的任何潜在对准差异最小化。

公开(公告)号：US08388610B2

公开(公告)日：2013-03-05

申请号：US12962318

申请日：2010-12-07

申请人： Gerhard Youssefi ,  Anton Hilger

发明人： Gerhard Youssefi ,  Anton Hilger

IPC分类号： A61B18/20

CPC分类号： A61F9/008 ,  A61F9/00806 ,  A61F9/00827 ,  A61F2009/00872 ,  A61F2009/0088 ,  A61F2009/00882

摘要： The invention relates to an apparatus and a method for determining the applicability of a treatment pattern for manipulation of a cornea of an eye using a laser. The concept of the present invention is based on the determination of an actual volumetric profile based on a set of input data and a theoretical volumetric profile which is created independently based on only the basic optical parameters. On the basis of a comparison of the determined volumetric profiles it is determined whether the actual volumetric profile is within predetermined tolerances.

摘要翻译： 本发明涉及一种用于确定用于使用激光操纵眼睛角膜的治疗模式的适用性的装置和方法。 本发明的概念基于基于一组输入数据和仅基于基本光学参数独立创建的理论体积分布来确定实际体积分布。 在确定的体积曲线的比较的基础上，确定实际体积曲线是否在预定公差内。

公开(公告)号：US07662149B2

公开(公告)日：2010-02-16

申请号：US11190052

申请日：2005-07-26

申请人： Josef Bille

发明人： Josef Bille

IPC分类号： A61B18/20

CPC分类号： A61F9/008 ,  A61B3/1015 ,  A61B3/107 ,  A61B2017/00017 ,  A61B2017/00022 ,  A61F9/00829 ,  A61F2009/00848 ,  A61F2009/00872 ,  A61F2009/0088

摘要： A method and system for customizing a flap created from a transparent material compensates for aberrations, particularly higher order aberrations, which are pre-existing or otherwise induced during creation of the flap. Before flap creation, the distorted wavefront of the transparent material is determined and the topology of the transparent material is defined in order to predict contributions likely to be encountered or induced by the stress distribution during creation of the flap. In view of the topology of the transparent material, a prototypic dissection path based on the distorted wavefront is refined to establish a refined dissection path. As a result, the flap is created along the refined dissection path to correct and minimize or eliminate the formation of higher order aberrations.

摘要翻译： 用于定制由透明材料制成的薄片的方法和系统补偿在瓣片创建期间预先存在或以其它方式诱导的像差，特别是较高阶像差。 在创建瓣片之前，确定透明材料的扭曲波前，并且定义透明材料的拓扑，以便预测在瓣片创建期间可能遇到的或由应力分布引起的贡献。 鉴于透明材料的拓扑结构，基于畸变波前的原型解剖路径被改进以建立精细的解剖路径。 结果，沿着精细的解剖路径产生瓣膜以校正和最小化或消除高阶像差的形成。

公开(公告)号：US07643521B2

公开(公告)日：2010-01-05

申请号：US11460567

申请日：2006-07-27

申请人： Frieder Loesel

发明人： Frieder Loesel

IPC分类号： H01S3/10 ,  B23K26/00

CPC分类号： B23K26/0622

摘要： A system for using a pulsed laser beam to process materials includes a selector for varying the pulse repetition rate of the laser beam. Also included is a control unit for identifying an optimal pulse repetition rate that is compatible with the required pulse energy level for processing the material. Variations in the pulse repetition rate can be made during a procedure pursuant to either pre-programmed instructions, or in response to closed loop feedback controls.

摘要翻译： 用于使用脉冲激光束来处理材料的系统包括用于改变激光束的脉冲重复率的选择器。 还包括用于识别与用于处理材料的所需脉冲能级相适应的最佳脉冲重复率的控制单元。 脉冲重复率的变化可以在程序期间根据预先编程的指令或响应闭环反馈控制进行。