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公开(公告)号：US09249132B2
公开(公告)日：2016-02-02
申请号：US13991973
申请日：2011-12-16
申请人： Xicheng Sun , Jian Qiu , Adam Stout
发明人： Xicheng Sun , Jian Qiu , Adam Stout
IPC分类号： C07D417/10 , C07D215/20 , C07D217/16 , C07D239/34 , C07D241/42 , C07D253/10 , C07D401/04 , C07D403/10 , C07D405/04 , C07D409/04 , C07D413/10 , C07C65/105 , C07C65/24 , C07D213/79 , C07D239/28 , C07D241/24 , C07D295/155 , C07D215/06 , C07D239/74 , C07D409/14 , C07D215/60 , C07D239/26 , C07D401/10 , C07D217/04
CPC分类号： A61K31/47 , A61K31/4709 , A61K31/472 , A61K31/498 , A61K31/517 , A61K31/53 , C07C65/105 , C07C65/17 , C07C65/24 , C07D213/79 , C07D215/06 , C07D215/20 , C07D215/60 , C07D217/04 , C07D217/16 , C07D237/24 , C07D239/26 , C07D239/28 , C07D239/34 , C07D239/74 , C07D241/24 , C07D241/42 , C07D249/18 , C07D253/10 , C07D257/04 , C07D295/155 , C07D401/04 , C07D401/10 , C07D403/10 , C07D405/04 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/10 , C12N9/0006 , C12N9/0065 , C12N9/99 , C12Y101/01284
摘要： The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
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2.发明申请公开(公告)号：US20130261123A1
公开(公告)日：2013-10-03
申请号：US13991972
申请日：2011-12-16
申请人： Xicheng Sun , Jian Qiu , Adam Stout
发明人： Xicheng Sun , Jian Qiu , Adam Stout
IPC分类号： C07D417/10 , C07D401/10 , C07D413/10 , C07D241/42 , C07D409/14 , C07D239/74 , C07D403/10 , C07D253/10 , C07D215/06 , C07D409/04
CPC分类号： A61K31/47 , A61K31/4709 , A61K31/472 , A61K31/498 , A61K31/517 , A61K31/53 , C07C65/105 , C07C65/17 , C07C65/24 , C07D213/79 , C07D215/06 , C07D215/20 , C07D215/60 , C07D217/04 , C07D217/16 , C07D237/24 , C07D239/26 , C07D239/28 , C07D239/34 , C07D239/74 , C07D241/24 , C07D241/42 , C07D249/18 , C07D253/10 , C07D257/04 , C07D295/155 , C07D401/04 , C07D401/10 , C07D403/10 , C07D405/04 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/10 , C12N9/0006 , C12N9/0065 , C12N9/99 , C12Y101/01284
摘要： The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
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3.发明申请公开(公告)号：US20130261122A1
公开(公告)日：2013-10-03
申请号：US13991973
申请日：2011-12-16
申请人： Xicheng Sun , Jian Qiu , Adam Stout
发明人： Xicheng Sun , Jian Qiu , Adam Stout
IPC分类号： C07C65/105 , C07D295/155 , C07D241/24 , C07D239/28 , C07C65/24 , C07D213/79
CPC分类号： A61K31/47 , A61K31/4709 , A61K31/472 , A61K31/498 , A61K31/517 , A61K31/53 , C07C65/105 , C07C65/17 , C07C65/24 , C07D213/79 , C07D215/06 , C07D215/20 , C07D215/60 , C07D217/04 , C07D217/16 , C07D237/24 , C07D239/26 , C07D239/28 , C07D239/34 , C07D239/74 , C07D241/24 , C07D241/42 , C07D249/18 , C07D253/10 , C07D257/04 , C07D295/155 , C07D401/04 , C07D401/10 , C07D403/10 , C07D405/04 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/10 , C12N9/0006 , C12N9/0065 , C12N9/99 , C12Y101/01284
摘要： The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
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4.发明授权Substituted quinoline compounds as S-nitrosoglutathione reductase inhibitors 有权取代的喹啉化合物作为S-亚硝基谷胱甘肽还原酶抑制剂公开(公告)号：US08921562B2
公开(公告)日：2014-12-30
申请号：US13824430
申请日：2011-10-07
申请人： Xicheng Sun , Jian Qiu , Adam Stout
发明人： Xicheng Sun , Jian Qiu , Adam Stout
IPC分类号： A61K31/53 , C07D215/04 , C07D215/54 , C07D215/00 , C07D401/04 , C07D215/42 , C07D215/60 , C07D401/10 , C07D409/04 , C07D417/10 , C07D409/14 , C07D215/20 , C07D413/10
CPC分类号： C07D215/20 , A61K31/47 , A61K31/4706 , A61K31/4709 , C07D215/00 , C07D215/42 , C07D215/46 , C07D215/54 , C07D215/60 , C07D401/04 , C07D401/10 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/10
摘要： The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
摘要翻译： 本发明涉及可用作S-亚硝基谷胱甘肽还原酶（GSNOR）抑制剂的新型喹啉化合物，包含这些化合物的药物组合物及其制备和使用方法。
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公开(公告)号：US20130178499A1
公开(公告)日：2013-07-11
申请号：US13824430
申请日：2011-10-07
申请人： Xicheng Sun , Jian Qiu , Adam Stout
发明人： Xicheng Sun , Jian Qiu , Adam Stout
IPC分类号： C07D215/20 , C07D401/04 , C07D413/10 , C07D215/54 , C07D417/10 , C07D215/60 , C07D409/14 , C07D215/42 , C07D401/10 , C07D409/04
CPC分类号： C07D215/20 , A61K31/47 , A61K31/4706 , A61K31/4709 , C07D215/00 , C07D215/42 , C07D215/46 , C07D215/54 , C07D215/60 , C07D401/04 , C07D401/10 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/10
摘要： The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
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6.发明授权Substituted bicyclic aromatic compounds as S-nitrosoglutathione reductase inhibitors 失效取代的双环芳族化合物作为S-亚硝基谷胱甘肽还原酶抑制剂公开(公告)号：US08785643B2
公开(公告)日：2014-07-22
申请号：US13991972
申请日：2011-12-16
申请人： Xicheng Sun , Jian Qiu , Adam Stout
发明人： Xicheng Sun , Jian Qiu , Adam Stout
IPC分类号： A61K31/53 , A61K31/50 , C07D215/04 , C07D237/26 , C07D239/72 , C07D239/34 , C07D405/04 , C07D217/16 , C07D253/10 , C07D403/10 , C07D409/04 , C07D215/06 , C07D241/24 , C07D239/74 , C07C65/24 , C07D417/10 , C07C65/105 , C07D213/79 , C07D409/14 , C07D295/155 , C07D215/20 , C07D401/10 , C07D239/28 , C07D413/10 , C07D241/42 , C07D401/04
CPC分类号： A61K31/47 , A61K31/4709 , A61K31/472 , A61K31/498 , A61K31/517 , A61K31/53 , C07C65/105 , C07C65/17 , C07C65/24 , C07D213/79 , C07D215/06 , C07D215/20 , C07D215/60 , C07D217/04 , C07D217/16 , C07D237/24 , C07D239/26 , C07D239/28 , C07D239/34 , C07D239/74 , C07D241/24 , C07D241/42 , C07D249/18 , C07D253/10 , C07D257/04 , C07D295/155 , C07D401/04 , C07D401/10 , C07D403/10 , C07D405/04 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/10 , C12N9/0006 , C12N9/0065 , C12N9/99 , C12Y101/01284
摘要： The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
摘要翻译： 本发明涉及用作S-亚硝基谷胱甘肽还原酶（GSNOR）抑制剂的新型取代的双环芳族化合物，包含这些化合物的药物组合物及其制备和使用方法。
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