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1.
公开(公告)号:US20070270434A1
公开(公告)日:2007-11-22
申请号:US11749742
申请日:2007-05-16
申请人: James W. Malecha , Stewart A. Noble , Sergio G. Duron , Andrew Lindstrom , Andrew Shiau , Steven Govek
发明人: James W. Malecha , Stewart A. Noble , Sergio G. Duron , Andrew Lindstrom , Andrew Shiau , Steven Govek
IPC分类号: A61K31/496 , A61K31/495
CPC分类号: C07D295/26
摘要: The present invention relates to compounds and methods useful as inhibitors of PPAR, particularly PPARδ, and for the treatment or prevention of PPAR-mediated diseases, including metabolic diseases.
摘要翻译: 本发明涉及可用作PPAR抑制剂,特别是PPARδ的化合物和方法,以及用于治疗或预防PPAR介导的疾病,包括代谢疾病。
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2.Aryl sulfonamide and sulfonyl compounds as modulators of PPAR and methods of treating metabolic disorders 审中-公开
标题翻译: 芳基磺酰胺和磺酰化合物作为PPAR的调节剂和治疗代谢紊乱的方法公开(公告)号:US20050234046A1
公开(公告)日:2005-10-20
申请号:US11102356
申请日:2005-04-07
申请人: Cunxiang Zhao , James Malecha , Stewart Noble , Sergio Duron , Andrew Lindstrom , Andrew Shiau
发明人: Cunxiang Zhao , James Malecha , Stewart Noble , Sergio Duron , Andrew Lindstrom , Andrew Shiau
IPC分类号: A61K31/407 , A61K31/445 , A61K31/451 , A61K31/454 , A61K31/4545 , A61K31/495 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/504 , A61K31/506 , A61K31/529 , A61K31/551 , C07D211/96 , C07D213/74 , C07D237/20 , C07D239/42 , C07D241/20 , C07D263/58 , C07D277/82 , C07D295/26 , C07D307/46 , C07D307/79 , C07D317/66 , C07D401/04 , C07D417/02 , C07D417/04 , C07D487/08 , C07D43/04
CPC分类号: C07D211/96 , C07D213/74 , C07D237/20 , C07D239/42 , C07D241/20 , C07D263/58 , C07D277/82 , C07D295/26 , C07D307/46 , C07D307/79 , C07D317/66 , C07D401/04 , C07D417/04 , C07D487/08
摘要: Aryl sulfonamide and sulfonyl compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
摘要翻译: 公开了作为过氧化物酶体增殖物激活受体的调节剂的芳基磺酰胺和磺酰化合物,包含其的药物组合物和使用其的治疗疾病的方法。
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公开(公告)号:US20060167012A1
公开(公告)日:2006-07-27
申请号:US11258463
申请日:2005-10-25
申请人: Stewart Noble , Guy Oshiro , James Malecha , Cunxiang Zhao , Carmen Robinson , Sergio Duron , Michael Sertic , Andrew Lindstrom , Andrew Shiau , Christopher Bayne , Mehmet Kahraman , Boliang Lou , Steven Govek
发明人: Stewart Noble , Guy Oshiro , James Malecha , Cunxiang Zhao , Carmen Robinson , Sergio Duron , Michael Sertic , Andrew Lindstrom , Andrew Shiau , Christopher Bayne , Mehmet Kahraman , Boliang Lou , Steven Govek
IPC分类号: A61K31/495 , A61K31/4439 , A61K31/44 , C07D403/02
CPC分类号: C07D213/74 , C07D209/08 , C07D211/96 , C07D257/04 , C07D295/26 , C07D333/60 , C07D401/04 , C07D401/12 , C07D405/04 , C07D409/12 , C07D487/08
摘要: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
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公开(公告)号:US20060205736A1
公开(公告)日:2006-09-14
申请号:US11435082
申请日:2006-05-16
申请人: Stewart Noble , Guy Oshiro , James Malecha , Cunxiang Zhao , Sergio Duron , Andrew Lindstrom , Andrew Shiau , Boliang Lou , Steven Govek , David Thomas
发明人: Stewart Noble , Guy Oshiro , James Malecha , Cunxiang Zhao , Sergio Duron , Andrew Lindstrom , Andrew Shiau , Boliang Lou , Steven Govek , David Thomas
IPC分类号: A61K31/495 , C07D241/04
CPC分类号: C07D209/08 , C07D209/26 , C07D211/96 , C07D213/74 , C07D241/04 , C07D257/04 , C07D295/26 , C07D317/66 , C07D333/60 , C07D401/04 , C07D401/12 , C07D405/04 , C07D409/12 , C07D487/08
摘要: Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
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