公开(公告)号：US08790739B2

公开(公告)日：2014-07-29

申请号：US13361396

申请日：2012-01-30

申请人： Justin Shimek ,  Andrew Peterson ,  Susan L Kamper ,  James W Geoffrion

发明人： Justin Shimek ,  Andrew Peterson ,  Susan L Kamper ,  James W Geoffrion

IPC分类号： A23G3/00

CPC分类号： A23G3/36 ,  A23G3/52

摘要： Dried soft aerated confections and methods of their preparation are provided having a water activity of about 0.1 to 0.4 and a glass transition temperature of less than 20° C. The confections comprise sugars, a foaming and a structuring ingredient, preferably each gelatin, and about 5 to 15% softening agent. Preferred softening agents include glycerin, polyglycerols and mixtures thereof. The confections are aerated to densities of about 0.1 to 0.5 g/cc. The soft dried aerated confections are particularly suited for addition to children's Ready-To-Eat cereals in the form of pieces weighing about 0.1 to 2 g each. The dried confection pieces maintain their soft texture over time without causing moisture migration to the cereal.

摘要翻译： 提供干燥的充气甜食及其制备方法，其水活度为约0.1至0.4，玻璃化转变温度低于20℃。糖果包括糖，发泡和结构成分，优选每种明胶，约 5〜15％软化剂。 优选的软化剂包括甘油，聚甘油和它们的混合物。 甜食充气至约0.1至0.5g / cc的密度。 柔软干燥的充气甜食特别适合于以每个重约0.1至2克的碎片形式添加到儿童即食谷物中。 干燥的甜食片段随着时间的推移保持其柔软的质地，而不会导致水分迁移到谷物。

公开(公告)号：US20140096846A1

公开(公告)日：2014-04-10

申请号：US13644279

申请日：2012-10-04

申请人： Andrew Peterson

发明人： Andrew Peterson

IPC分类号： F16K21/04

CPC分类号： A45F3/18 ,  Y10T137/7837

摘要： Embodiments of the apparatus is a personal hydration apparatus comprising a drink manifold with a receptor configured such that a water tight seal can form between a threaded bottle and the receptor. A check valve is coupled to the drink manifold configure to allow air into manifold and a first tube coupled to the manifold that is configured to allow liquid to be drawn from the threaded bottle. The hydration manifold allows an individual the convenience of using a conventional bottle filled with liquid in a hydration system accessible through a hose.

摘要翻译： 该装置的实施方案是一种个人水合装置，其包括具有接收器的饮料歧管，其配置为使得在带螺纹的瓶子和受体之间形成防水密封。 止回阀联接到饮料歧管，其构造为允许空气进入歧管，并且联接到歧管的第一管被配置成允许液体从螺纹瓶中抽出。 水合歧管允许个人在通过软管可接近的水合系统中使用填充有液体的常规瓶子的方便。

公开(公告)号：US20140096844A1

公开(公告)日：2014-04-10

申请号：US13644267

申请日：2012-10-04

申请人： Andrew Peterson

发明人： Andrew Peterson

IPC分类号： F16K15/00

CPC分类号： A45F3/16 ,  Y10T137/7837

摘要： Embodiments of the apparatus is a personal hydration apparatus comprising a drink manifold with a receptor configured such that a water tight seal can form between a threaded bottle and the receptor. A check valve is coupled to the drink manifold configure to allow air into manifold and a first tube coupled to the manifold that is configured to allow liquid to be drawn from the threaded bottle. The hydration manifold allows an individual the convenience of using a conventional bottle filled with liquid in a hydration system accessible through a hose.

摘要翻译： 该装置的实施方案是一种个人水合装置，其包括具有接收器的饮料歧管，其配置为使得在带螺纹的瓶子和受体之间形成防水密封。 止回阀联接到饮料歧管，其构造为允许空气进入歧管，并且联接到歧管的第一管被配置成允许液体从螺纹瓶中抽出。 水合歧管允许个人在通过软管可接近的水合系统中使用填充有液体的常规瓶子的方便。

公开(公告)号：US08105642B2

公开(公告)日：2012-01-31

申请号：US10620038

申请日：2003-07-15

申请人： Justin Shimek ,  Andrew Peterson ,  Susan L. Kamper ,  James W. Geoffrion

发明人： Justin Shimek ,  Andrew Peterson ,  Susan L. Kamper ,  James W. Geoffrion

IPC分类号： A23G3/00

CPC分类号： A23G3/36 ,  A23G3/52

摘要： Dried soft aerated confections and methods of their preparation are provided having a water activity of about 0.1 to 0.4 and a glass transition temperature of less than 20° C. The confections comprise sugars, a foaming and a structuring ingredient, preferably each gelatin, and about 5 to 15% softening agent. Preferred softening agents include glycerin, polyglycerols and mixtures thereof. The confections are aerated to densities of about 0.1 to 0.5 g/cc. The soft dried aerated confections are particularly suited for addition to children's Ready-To-Eat cereals in the form of pieces weighing about 0.1 to 2 g each. The dried confection pieces maintain their soft texture over time without causing moisture migration to the cereal.

摘要翻译： 提供干燥的充气甜食及其制备方法，其水活度为约0.1至0.4，玻璃化转变温度低于20℃。糖果包括糖，发泡和结构成分，优选每种明胶，约 5〜15％软化剂。 优选的软化剂包括甘油，聚甘油及其混合物。 甜食充气至约0.1至0.5g / cc的密度。 柔软干燥的充气甜食特别适合于以每个重约0.1至2克的碎片形式添加到儿童即食谷物中。 干燥的甜食片段随着时间的推移保持其柔软的质地，而不会导致水分迁移到谷物。

公开(公告)号：US20110097330A1

公开(公告)日：2011-04-28

申请号：US11722967

申请日：2006-02-27

申请人： Allison Anne Byers Horner ,  Catherine Batac Clarke ,  Katherin E. Combs ,  Frederic J. de Sauvage ,  Joel Edwards ,  Paul Godowski ,  Deanna Grant Wilson ,  Wenhu Huang ,  Lorelei Diane Ketcherside ,  Erin Marie Massey ,  Charles Montgomery ,  Bobby Joe Payne ,  Andrew Peterson ,  Ni Nancy Qian ,  Jeffrey J. Schrick ,  Zheng-Zheng Shi ,  Mary Jean Sparks ,  Joy Anne Stala ,  Colleen M. Viator ,  Peter Vogel ,  Weilan Ye ,  Jung-Hua Yeh ,  Zhiyong Ding

发明人： Allison Anne Byers Horner ,  Catherine Batac Clarke ,  Katherin E. Combs ,  Frederic J. de Sauvage ,  Joel Edwards ,  Paul Godowski ,  Deanna Grant Wilson ,  Wenhu Huang ,  Lorelei Diane Ketcherside ,  Erin Marie Massey ,  Charles Montgomery ,  Bobby Joe Payne ,  Andrew Peterson ,  Ni Nancy Qian ,  Jeffrey J. Schrick ,  Zheng-Zheng Shi ,  Mary Jean Sparks ,  Joy Anne Stala ,  Colleen M. Viator ,  Peter Vogel ,  Weilan Ye ,  Jung-Hua Yeh ,  Zhiyong Ding

IPC分类号： A61K49/00 ,  C07K16/18 ,  A61K39/00 ,  A61P25/00 ,  A61P9/00 ,  A61P37/00 ,  A61P27/02 ,  A61P25/24 ,  A61P25/22 ,  A61P25/18 ,  A61P27/06 ,  A61P27/12 ,  A61P9/10 ,  A61P19/02 ,  A61P19/10 ,  C12Q1/68 ,  C12N5/071 ,  C12N5/0735 ,  C12Q1/02

CPC分类号： C07K14/47 ,  A01K2217/075 ,  A61K2039/505 ,  G01N2500/00

摘要： The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO179, PRO181, PRO244, PRO247, PRO269, PRO293, PRO298, PRO339, PRO341, PRO347, PRO531, PRO537, PRO718, PRO773, PRO860, PRO871, PRO872, PRO813, PRO828, PRO1100, PRO1114, PRO115, PRO1126, PRO1133, PRO1154, PRO1185, PRO1194, PRO1287, PRO1291, PRO1293, PRO1310, PRO1312, PRO1335, PRO1339, PRO2155, PRO1356, PRO1385, PRO1412, PRO1487, PRO1758, PRO1779, PRO1785, PRO1889, PRO90318, PRO3434, PRO3579, PRO4322, PRO4343, PRO4347, PRO4403, PRO4976, PRO260, PRO6014, PRO6027, PRO6181, PRO6714, PRO9922, PRO7179, PRO7476, PRO9824, PRO19814, PRO19836, PRO20088, PRO70789, PRO50298, PRO51592, PRO1757, PRO4421, PRO9903, PRO1106, PRO1411, PRO1486, PRO1565, PRO4399 or PRO4404 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.

摘要翻译： 本发明涉及转基因动物，以及与基因功能表征相关的组合物和方法。 具体地说，本发明提供转基因小鼠，其包括PRO179，PRO181，PRO244，PRO247，PRO269，PRO293，PRO298，PRO339，PRO341，PRO347，PRO531，PRO537，PRO718，PRO773，PRO860，PRO871，PRO872，PRO813，PRO828，PRO1100中的中断 ，PRO1114，PRO115，PRO1126，PRO1133，PRO1154，PRO1185，PRO1194，PRO1287，PRO1291，PRO1293，PRO1310，PRO1312，PRO1335，PRO1339，PRO2155，PRO1356，PRO1385，PRO1412，PRO1487，PRO1758，PRO1779，PRO1785，PRO1889，PRO90318，PRO3434 ，PRO3579，PRO4322，PRO4343，PRO4347，PRO4403，PRO4976，PRO260，PRO6014，PRO6027，PRO6181，PRO6714，PRO9922，PRO7179，PRO7476，PRO9824，PRO19814，PRO19836，PRO20088，PRO70789，PRO50298，PRO51592，PRO1757，PRO4421，PRO9903，PRO1106 ，PRO1411，PRO1486，PRO1565，PRO4399或PRO4404基因。 这样的体内研究和表征可以提供有用的识别和发现治疗和/或治疗用于预防，改善或矫正与基因中断相关的疾病或功能障碍如神经障碍; 心血管，内皮或血管生成障碍; 眼睛异常; 免疫学障碍; 肿瘤疾病; 骨代谢异常或障碍; 脂代谢紊乱 或发育异常。

公开(公告)号：US5955264A

公开(公告)日：1999-09-21

申请号：US320663

申请日：1994-10-11

申请人： Brian Seed ,  Andrew Peterson

发明人： Brian Seed ,  Andrew Peterson

IPC分类号： G01N33/53 ,  C07K7/08 ,  C07K14/00 ,  C07K14/435 ,  C07K14/705 ,  C07K14/73 ,  C12N5/10 ,  C12N7/04 ,  C12N15/09 ,  C12N15/10 ,  C12P21/02 ,  C12R1/91 ,  G01N33/569 ,  G01N33/577 ,  G01N33/68 ,  C12Q1/68

CPC分类号： C12N15/1086 ,  C07K14/70514 ,  C12N15/1034 ,  G01N33/56972 ,  G01N33/56988 ,  G01N33/6878

摘要： A rapid mutational analysis method for mapping protein epitopes is disclosed. This method has been used to identify the binding sites for 16 anti-CD2 and anti-CD4 monoclonal antibodies. The powerful, rapid, and simple method of the present invention allows isolation of a very large number of mutants, and is applicable to any intracellular or surface protein for which a cDNA and monoclonal antibodies are available. The present method is especially useful in ligand binding site studies for the design of new ligands and drugs.

摘要翻译： 公开了用于测定蛋白质表位的快速突变分析方法。 该方法已被用于鉴定16种抗CD2和抗CD4单克隆抗体的结合位点。 本发明的强大，快速和简单的方法允许分离非常大量的突变体，并且可应用于可获得cDNA和单克隆抗体的任何细胞内或表面蛋白质。 本方法在配体结合位点研究中特别适用于新配体和药物的设计。

公开(公告)号：US08911634B2

公开(公告)日：2014-12-16

申请号：US13569129

申请日：2012-08-07

申请人： Windsor Owens ,  Andrew Peterson ,  Yuri Osipchuk ,  Edward Verdonk

发明人： Windsor Owens ,  Andrew Peterson ,  Yuri Osipchuk ,  Edward Verdonk

IPC分类号： B01D33/15

CPC分类号： G01N1/4077

摘要： A device for separating materials of different densities is provided. A cup body has an internal cavity configured to hold media. An inner wall defines a central body region having an upper and lower end. The upper end is wider than the lower end. An interior shoulder circumscribes the upper end of the central body region. The interior shoulder defines a neck region above the central body region and a shoulder trap below the neck region. The shoulder trap circumscribes the upper end of the central body region and is wider than the neck region. When the device is spun about a central axis, the media travels upward along the inner wall toward the shoulder trap. Relatively more dense material in the media is collected in the shoulder trap, and relatively less dense material is expelled from the device through an opening above the neck region.

摘要翻译： 提供了用于分离不同密度的材料的装置。 杯体具有构造成保持介质的内部空腔。 内壁限定具有上端和下端的中心体区域。 上端比下端宽。 内部肩膀限定中心体区域的上端。 内部肩部限定在中心身体区域上方的颈部区域和在颈部区域下方的肩陷阱。 肩部陷阱围绕中心体区域的上端并且比颈部区域宽。 当设备围绕中心轴线旋转时，介质沿着内壁朝向肩部陷阱向上行进。 介质中相对较致密的材料被收集在肩陷阱中，并且相对较不致密的材料通过颈部区域上方的开口从装置排出。

公开(公告)号：US20140045206A1

公开(公告)日：2014-02-13

申请号：US13569129

申请日：2012-08-07

申请人： Windsor Owens ,  Andrew Peterson ,  Yuri Osipchuk ,  Edward Verdonk

发明人： Windsor Owens ,  Andrew Peterson ,  Yuri Osipchuk ,  Edward Verdonk

IPC分类号： G01N1/28 ,  C12Q1/02

CPC分类号： G01N1/4077

摘要： A device for separating materials of different densities is provided. A cup body has an internal cavity configured to hold media. An inner wall defines a central body region having an upper and lower end. The upper end is wider than the lower end. An interior shoulder circumscribes the upper end of the central body region. The interior shoulder defines a neck region above the central body region and a shoulder trap below the neck region. The shoulder trap circumscribes the upper end of the central body region and is wider than the neck region. When the device is spun about a central axis, the media travels upward along the inner wall toward the shoulder trap. Relatively more dense material in the media is collected in the shoulder trap, and relatively less dense material is expelled from the device through an opening above the neck region.

摘要翻译： 提供了用于分离不同密度的材料的装置。 杯体具有构造成保持介质的内部空腔。 内壁限定具有上端和下端的中心体区域。 上端比下端宽。 内部肩膀限定中心体区域的上端。 内部肩部限定在中心身体区域上方的颈部区域和在颈部区域下方的肩陷阱。 肩部陷阱围绕中心体区域的上端并且比颈部区域宽。 当设备围绕中心轴线旋转时，介质沿着内壁朝向肩部陷阱向上行进。 介质中相对较致密的材料被收集在肩陷阱中，并且相对较不致密的材料通过颈部区域上方的开口从装置排出。

公开(公告)号：US08584998B1

公开(公告)日：2013-11-19

申请号：US13200680

申请日：2011-09-28

申请人： Andrew Peterson

发明人： Andrew Peterson

IPC分类号： A47F5/00

CPC分类号： F24F13/32 ,  F24F1/027

摘要： A window air conditioning mounting system comprising a base subassembly having generally I-shaped configuration. There is also a shackle being coupled to the base subassembly. There is a strut having a generally T-shaped configuration coupled to the shackle and to the base subassembly. Lastly there is an upper cross member comprising a pair of generally C-shaped components. The components slidably receiving each other.

摘要翻译： 一种窗户空调安装系统，其包括具有大致I形构造的基座子组件。 还有一个钩环耦合到基座子组件。 存在具有与钩环和基部子组件耦合的大致T形配置的支柱。 最后有一个上横向构件，其包括一对大致C形的构件。 这些部件可滑动地彼此接收。

公开(公告)号：US20130032605A1

公开(公告)日：2013-02-07

申请号：US13195843

申请日：2011-08-02

申请人： Andrew Peterson

发明人： Andrew Peterson

IPC分类号： A47G19/22

CPC分类号： A47G19/2266 ,  A45F3/16

摘要： Embodiments of the apparatus is a personal hydration apparatus comprising a drink manifold with a receptor configured such that a water tight seal can form between a threaded bottle and the receptor. A check valve is coupled to the drink manifold configure to allow air into manifold and a first tube coupled to the manifold that is configured to allow liquid to be drawn from the threaded bottle. The hydration manifold allows an individual the convenience of using a conventional bottle filled with liquid in a hydration system accessible through a hose.

摘要翻译： 该装置的实施方案是一种个人水合装置，其包括具有接收器的饮料歧管，其配置为使得在带螺纹的瓶子和受体之间形成防水密封。 止回阀联接到饮料歧管，其构造为允许空气进入歧管，并且联接到歧管的第一管被配置成允许液体从螺纹瓶中抽出。 水合歧管允许个人在通过软管可接近的水合系统中使用填充有液体的常规瓶子的方便。