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公开(公告)号：US20170020813A1
公开(公告)日：2017-01-26
申请号：US15220732
申请日：2016-07-27
申请人： Michael M. Lipp , Jean C. Sung
发明人： Michael M. Lipp , Jean C. Sung
IPC分类号： A61K9/00 , A61K47/02 , A61K31/5383
CPC分类号： A61K9/0075 , A61K9/1611 , A61K31/198 , A61K31/5383 , A61K33/06 , A61K33/14 , A61K47/02 , A61K2300/00
摘要： The invention relates to respirable dry particles that contain one or more divalent metal cations, such as magnesium, in an amount of less than 3% by weight, and to dry powders that contain the respirable particles. The dry particles can further contain an active agent, or can be used as carrier particles to deliver an active agent.
摘要翻译： 本发明涉及含有少于3重量％的一种或多种二价金属阳离子如镁的可吸入干颗粒，以及含有可吸入颗粒的干燥粉末。 干颗粒可以进一步含有活性剂，或可用作载体颗粒以递送活性剂。
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2.发明授权Respirably dry powder comprising calcium lactate, sodium chloride and leucine 有权包含乳酸钙，氯化钠和亮氨酸的重要干燥粉末公开(公告)号：US08758824B2
公开(公告)日：2014-06-24
申请号：US13504284
申请日：2011-08-26
申请人： Michael M. Lipp , Jean C. Sung
发明人： Michael M. Lipp , Jean C. Sung
CPC分类号： A61K9/14 , A61K9/0075 , A61K9/1611 , A61K9/1617 , A61K31/19 , A61K31/198 , A61K31/56 , A61K33/06 , A61K33/14 , A61K45/06 , Y02A50/473 , A61K2300/00
摘要： The present invention relates to respirable dry powders that contain respirable dry particles that comprise about 20% (w/w) leucine, about 75% (w/w) calcium lactate, and about 5% (w/w) sodium chloride, or about 37.5% (w/w) leucine, about 58.6% (w/w) calcium lactate, and about 3.9% (w/w) sodium chloride, and methods for treating a subject using the respirable dry powders.
摘要翻译： 本发明涉及可吸入干粉，其包含可吸入干颗粒，其包含约20％（w / w）亮氨酸，约75％（w / w）乳酸钙和约5％（w / w）氯化钠，或约 37.5％（w / w）亮氨酸，约58.6％（w / w）乳酸钙和约3.9％（w / w）氯化钠，以及使用可呼吸干燥粉末治疗受试者的方法。
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公开(公告)号：US20130266653A1
公开(公告)日：2013-10-10
申请号：US13876312
申请日：2011-09-29
申请人： Michael M. Lipp , Jean C. Sung
发明人： Michael M. Lipp , Jean C. Sung
IPC分类号： A61K9/00
CPC分类号： A61K9/0073 , A61K9/0075 , A61K31/137 , A61K31/407 , A61K31/439 , A61K31/4745 , A61K31/496 , A61K31/5383 , A61K31/56 , A61K31/58 , A61K31/7036 , A61K38/00 , A61K38/28 , A61K39/00 , A61K39/395 , A61K2300/00
摘要： The present invention is directed toward respirable dry powders and particles for systemic delivery of pharmaceutically active agents or delivery to the respiratory tract. The dry powders contain one or more monovalent metal cations (such as Na+), are small and dispersible.
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公开(公告)号：US20130213398A1
公开(公告)日：2013-08-22
申请号：US13817963
申请日：2011-08-26
申请人： Michael M. Lipp , Jean C. Sung , Robert W. Clarke , David L. Hava
发明人： Michael M. Lipp , Jean C. Sung , Robert W. Clarke , David L. Hava
CPC分类号： A61K47/02 , A61K9/0073 , A61K9/0075 , A61K31/137 , A61K31/198 , A61K33/06 , A61K33/14 , A61K47/12 , A61K47/183 , A61K2300/00 , A61M15/00 , B22F3/1125 , B22F5/10 , C22C21/00
摘要： The present invention is directed toward respirable dry particles for delivery of divalent metal cation salts and/or monovalent cation salts to the respiratory tract and methods for treating a subject having a respiratory disease and/or infection.
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公开(公告)号：US07690361B2
公开(公告)日：2010-04-06
申请号：US11905410
申请日：2007-09-28
CPC分类号： F02M59/20 , F02M59/366 , Y10T137/85986
摘要： A system and method for metering fuel is provided which includes a fuel supply line and a metering valve in fluid connection with the fuel supply line to control a flow of fuel through the fuel supply line. The valve is movable into a closed position to block a primary flow of fuel and create a leakage fuel flow in the fuel supply line downstream of the metering valve. The system also includes a venturi apparatus fluidly coupled to the fuel supply line upstream of the metering valve. The venturi apparatus is further coupled to the fuel supply line downstream of the metering valve to direct the leakage fuel flow out of the fuel supply line.
摘要翻译： 提供了一种用于计量燃料的系统和方法，其包括与燃料供应管线流体连接的燃料供应管线和计量阀，以控制通过燃料供应管线的燃料流。 阀门可移动到关闭位置以阻挡燃料的主流，并在计量阀下游的燃料供应管线中产生泄漏燃料流。 该系统还包括流体耦合到计量阀上游的燃料供应管线的文氏管装置。 文丘里装置进一步联接到计量阀下游的燃料供应管线，以将泄漏的燃料流引导出燃料供应管线。
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公开(公告)号：US20090084355A1
公开(公告)日：2009-04-02
申请号：US11905410
申请日：2007-09-28
CPC分类号： F02M59/20 , F02M59/366 , Y10T137/85986
摘要： A system and method for metering fuel is provided which includes a fuel supply line and a metering valve in fluid connection with the fuel supply line to control a flow of fuel through the fuel supply line. The valve is movable into a closed position to block a primary flow of fuel and create a leakage fuel flow in the fuel supply line downstream of the metering valve. The system also includes a venturi apparatus fluidly coupled to the fuel supply line upstream of the metering valve. The venturi apparatus is further coupled to the fuel supply line downstream of the metering valve to direct the leakage fuel flow out of the fuel supply line.
摘要翻译： 提供了一种用于计量燃料的系统和方法，其包括与燃料供应管线流体连接的燃料供应管线和计量阀，以控制通过燃料供应管线的燃料流。 阀门可移动到关闭位置以阻挡燃料的主流，并在计量阀下游的燃料供应管线中产生泄漏燃料流。 该系统还包括流体耦合到计量阀上游的燃料供应管线的文氏管装置。 文丘里装置进一步联接到计量阀下游的燃料供应管线，以将泄漏的燃料流引导出燃料供应管线。
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公开(公告)号：US20050164447A1
公开(公告)日：2005-07-28
申请号：US11085663
申请日：2005-03-21
申请人： Kangguo Cheng , Ramachandra Divakaruni , C. Sung
发明人： Kangguo Cheng , Ramachandra Divakaruni , C. Sung
IPC分类号： H01L27/108 , H01L21/336 , H01L21/8242 , H01L27/02
CPC分类号： H01L27/10876 , H01L27/0207 , H01L27/10864 , H01L27/1087 , H01L29/945
摘要： A method and structure for a memory storage cell in a semiconductor substrate includes forming a dopant source material over a lower portion of a deep trench formed in the substrate. An upper portion of the trench is shaped to a generally rectangular configuration, and the dopant source material is annealed so as to form a buried plate of a trench capacitor. The buried plate is self aligned to the shaped upper portion of the trench.
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公开(公告)号：US06837221B2
公开(公告)日：2005-01-04
申请号：US10179017
申请日：2002-06-26
CPC分类号： F02M63/004 , F02M47/027 , F02M63/0026 , F02M63/0043 , F02M65/005 , F02M2200/28
摘要： An injector is provided which includes a nozzle valve element, a control volume, and an injection control valve including a control valve member for controlling fuel flow from the control volume so as to control nozzle valve movement. Importantly, the injector includes a nozzle valve lift detecting device for detecting nozzle valve lift and providing a nozzle valve element lift feedback signal. Feedback signals are improved and control valve member oscillations are minimized by positioning a valve seat associated with the control valve member a spaced distance from the control volume, positioning a drain orifice such that the nozzle valve element restricts flow through a drain circuit when in an open position and extending the control valve member from the valve seat to the control volume to form an end wall of the control volume.
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公开(公告)号：US5250208A
公开(公告)日：1993-10-05
申请号：US864817
申请日：1992-04-02
申请人： Abid N. Merchant , Janet C. Sung
发明人： Abid N. Merchant , Janet C. Sung
IPC分类号： A62D1/08 , C07C19/045 , C07C19/08 , C07C21/073 , C07C31/04 , C07C31/08 , C07C31/10 , C08J9/14 , C09K3/30 , C09K5/04 , C11D7/50 , C23G5/028 , C11D7/30
CPC分类号： C09K5/045 , C08J9/149 , C11D7/5081 , C23G5/02803 , C08J2207/04 , C09K2205/102 , C09K2205/122 , C09K2205/32 , Y10S264/05
摘要： Azeotropic or azeotrope-like compositions of effective amounts of 1,1,2,2,3,3,4,4,-octofluorobutane; trans-1,2-dichloroethylene, cis-1,2-dichloroethylene, 1,1-dichloroethane, or 1,3-dichloro-1,2,2,3,3-HCFC-225cb; and an alcohol such as methanol, ethanol, or isopropanol, to form an azeotropic or azeotrope-like composition are disclosed that are useful as cleaning agents, refrigerants, aerosol propellants, heat transfer media, gaseous dielectrics, fire extinguishing agents, expansion agents for polyolefins and polyurethanes and as power cycle working fluids.
摘要翻译： 有效量的1,1,2,2,3,3,4,4， - 八氟丁烷的共沸或类共沸组合物; 反-1,2-二氯乙烯，顺-1,2-二氯乙烯，1,1-二氯乙烷或1,3-二氯-1,2,2,3,3-HCFC-225cb; 和醇如甲醇，乙醇或异丙醇以形成共沸或共沸组合物，其可用作清洁剂，制冷剂，气溶胶推进剂，传热介质，气体电介质，灭火剂，聚烯烃膨胀剂 和聚氨酯和作为动力循环工作流体。
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公开(公告)号：US09061352B2
公开(公告)日：2015-06-23
申请号：US13817963
申请日：2011-08-26
申请人： Michael M. Lipp , Jean C. Sung
发明人： Michael M. Lipp , Jean C. Sung
CPC分类号： A61K47/02 , A61K9/0073 , A61K9/0075 , A61K31/137 , A61K31/198 , A61K33/06 , A61K33/14 , A61K47/12 , A61K47/183 , A61K2300/00 , A61M15/00 , B22F3/1125 , B22F5/10 , C22C21/00
摘要： The present invention is directed toward respirable dry particles for delivery of divalent metal cation salts and/or monovalent cation salts to the respiratory tract and methods for treating a subject having a respiratory disease and/or infection.
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