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1.发明申请Novel Formulations of Fat-Soluble Active Ingredients with High Biovailability 审中-公开具有高生物利用度的脂溶性活性成分的新型配方公开(公告)号：US20080299209A1
公开(公告)日：2008-12-04
申请号：US12064886
申请日：2006-10-20
申请人： Markus Beck , Hansjoerg Grass , Bruno Leuenberger , Markus Nowotny , Christian Schafer , Karl Manfred Voelker
发明人： Markus Beck , Hansjoerg Grass , Bruno Leuenberger , Markus Nowotny , Christian Schafer , Karl Manfred Voelker
IPC分类号： A61K9/14 , A61K31/01 , A61K31/015 , A61K31/047 , A61K31/122 , A61K31/215 , A23L1/29
CPC分类号： A61K9/2081 , A23K20/174 , A23K20/179 , A23L5/44 , A23L33/155 , A23V2002/00 , A61K8/0241 , A61K8/31 , A61K9/2013 , A61K9/2018 , A61K9/2059 , A61K31/01 , A61K31/047 , A61K2800/52 , A61K2800/56 , A61Q19/00
摘要： The present invention relates to formulations of a pharmacological effective fat-soluble active ingredient with a high bioavailability of said fat-soluble active ingredient as well as to their manufacture and use as dietary supplement, food, feed, personal care product and/or pharmaceutical. Such formulations are those which when dissolved, dispersed or diluted in/with water have an extinction E 1/1 at a wavelength in the range of from 200 to 800 nm, preferably in the range of from 250 to 600 nm, more preferably in the range of from 250 to 500 nm, more preferably in the range of from 370 to 485 nm, of ≧380, preferably of ≧600, most preferably ≧900. In preferred embodiments of the formulations of the present invention such formulations show an extrusion loss of fat-soluble active ingredient of ≦30% when pressed to tablets.
摘要翻译： 本发明涉及具有所述脂溶性活性成分的高生物利用度的药理学有效的脂溶性活性成分以及作为膳食补充剂，食品，饲料，个人护理产品和/或药物的制造和用途的制剂。 这种制剂是当在水中溶解，分散或稀释时在200至800nm范围内，优选在250至600nm范围内的波长具有消光E 1/1，更优选在 范围为250至500nm，更优选为370至485nm，≥380，优选> = 600，最优选> = 900。 在本发明制剂的优选实施方案中，这些制剂显示当压制成片剂时，脂溶性活性成分的挤出损失<= 30％。
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公开(公告)号：US20060099325A1
公开(公告)日：2006-05-11
申请号：US10517714
申请日：2003-06-11
IPC分类号： A23J1/00
CPC分类号： C07K14/415 , A23J1/142 , A23J1/148
摘要： The invention relates to vegetable protein preparations (isolates and concentrates) with improved sensory properties due to enzymatic treatment of the raw material with a lipase during the isolation process and the use of these protein preparations.
摘要翻译： 本发明涉及具有改善的感官特性的植物蛋白制剂（分离物和浓缩物），这是由于在分离过程中用脂肪酶酶处理原料和使用这些蛋白质制剂。
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公开(公告)号：US20100120713A1
公开(公告)日：2010-05-13
申请号：US12571321
申请日：2009-09-30
IPC分类号： A61K31/715 , A23L1/48 , A23B4/03 , A23L2/00
CPC分类号： A23L2/58 , A23L5/42 , A23L5/44 , A23L29/20 , A23L29/212 , A23L33/155 , A23V2002/00 , A61K8/31 , A61K8/732 , A61K9/20 , A61K9/48 , A61Q19/00 , C08K5/0008 , C08L3/02 , C08L3/04 , C08L3/06 , A23V2250/5036 , A23V2250/5118
摘要： The present invention relates to compositions for the enrichment, fortification and/or coloration of food, beverages, animal feed, cosmetics or pharmaceutical compositions comprising at least one modified starch, β-carotene and optionally at least an adjuvant and/or an excipient, wherein a mixture of the composition with water has a color hue in the range of 48 to 60.
摘要翻译： 本发明涉及用于富集，强化和/或着色食品，饮料，动物饲料，化妆品或药物组合物的组合物，其包含至少一种改性淀粉，胡萝卜素和任选至少一种佐剂和/或赋形剂， 其中所述组合物与水的混合物具有在48至60的范围内的色调。
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公开(公告)号：US20090105331A1
公开(公告)日：2009-04-23
申请号：US12162699
申请日：2007-02-06
IPC分类号： A61K31/355 , C07H1/00 , A61K47/00 , A61K31/015 , A23L2/00 , A23L1/27 , A61K31/20 , A61K31/07
CPC分类号： A23L2/58 , A23L5/42 , A23L5/44 , A23L29/20 , A23L29/212 , A23L33/155 , A23V2002/00 , A61K8/31 , A61K8/732 , A61K9/20 , A61K9/48 , A61Q19/00 , C08K5/0008 , C08L3/02 , C08L3/04 , C08L3/06 , A23V2250/5036 , A23V2250/5118
摘要： The present invention relates to compositions containing fat-soluble active ingredients and/or colorants in a matrix based on improved modified polysaccharides, i.e. modified polysaccharides where parts were separated, and to a process for preparing these compositions as well as to these improved modified polysaccharides themselves and a process for the manufacture thereof. The present invention further relates to the use of the compositions of this invention for the enrichment, fortification and/or for the coloration of food, beverages, animal feed, cosmetics and pharmaceutical compositions and to such food, beverages, animal feed, cosmetics and pharmaceutical compositions themselves.
摘要翻译： 本发明涉及基于改进的改性多糖，即其中分离部分的改性多糖的基质中含有脂溶性活性成分和/或着色剂的组合物，以及制备这些组合物的方法以及这些改进的改性多糖本身 及其制造方法。 本发明还涉及本发明的组合物用于食品，饮料，动物饲料，化妆品和药物组合物的富集，强化和/或着色以及这种食品，饮料，动物饲料，化妆品和药物 组合本身。
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公开(公告)号：US20080241320A1
公开(公告)日：2008-10-02
申请号：US11729981
申请日：2007-03-30
CPC分类号： A23J3/346 , A23J1/125 , A23J3/14 , A23K20/147 , A23L2/66 , A23L5/43 , A23L7/152 , A23L33/15 , A23L33/155 , A23L33/18 , A23P10/30 , A23V2002/00 , C07K14/415 , A23V2200/30 , A23V2200/224 , A23V2250/5482 , A23V2250/712 , A23V2250/211
摘要： Partially deamidated rice endosperm protein or rice endosperm protein which is partially conjugated with mono-, di-, oligo- or polysaccharides is used as novel protective hydrocolloid for fat-soluble active ingredients and/or fat-soluble colorants. The present invention further includes compositions comprising that rice endosperm protein and at least one fat-soluble active ingredient/colorant, as well as their manufacture, that rice endosperm protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions. The present invention is directed to theses uses and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a rice endosperm protein and such a composition, respectively.
摘要翻译： 与单糖，二糖，多糖或多糖部分结合的部分脱酰胺水稻胚乳蛋白或水稻胚乳蛋白被用作脂溶性活性成分和/或脂溶性着色剂的新型保护性水胶体。 本发明还包括包含水稻胚乳蛋白质和至少一种脂溶性活性成分/着色剂的组合物，以及它们的制造，即水稻胚乳蛋白质本身及其制造。 这些组合物用于食品，饮料，动物饲料，个人护理或药物组合物的富集，强化和/或着色。 本发明涉及这些用途以及分别含有这种水稻胚乳蛋白质的食品，饮料，动物饲料，个人护理和药物组合物。
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公开(公告)号：US20080022955A1
公开(公告)日：2008-01-31
申请号：US11879904
申请日：2007-07-19
IPC分类号： F01L1/20
CPC分类号： F01L1/24
摘要： A hydraulic valve lash adjuster for a valve train of an internal combustion engine, for example for an automotive vehicle, said hydraulic valve lash adjuster comprising a piston (2) that is guided for displacement in a piston housing (4) and elastically supported against said housing, said piston (2) comprising a low pressure chamber (3) that communicates via an axial opening (26) in a piston bottom (19) with a high pressure chamber (5) defined by the piston housing (4) and the piston (2), and further comprising a control valve (6) acting between said pressure chambers (3, 5), said control valve (6) comprising a valve closing body (7) that can be brought to bear sealingly against a valve seat (24) that surrounds the axial opening (26) on a piston body undersurface (28) and is received in a closing body cap (9) whose cap bottom (21) acts as a stroke limitation of the valve closing body (7), and said control valve (6) further comprising a control valve spring (8) that loads the valve closing body (7) in opening direction, and, during a collapsing movement between the piston (2) and the piston housing (4), said valve closing body (7) being hydraulically loadable in closing direction against the biasing force of the control valve spring (8) by a pressure build-up in the high pressure chamber (5).To improve the valve lash adjuster so that undesired operational fluctuations are reduced, the valve closing body (7) is configured as a needle-shaped, elongate sealing piston whose valve seat-proximate end comprises a plate-shaped sealing surface (10) that cooperates with a correspondingly configured sealing surface (25) of the valve seat (24) and whose valve seat-distal end comprises a surface of application (12) for hydraulic loading, and the valve closing body (7) substantially fills a space volume of the closing body cap (9) surrounding the valve closing body (7).
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公开(公告)号：US20050130777A1
公开(公告)日：2005-06-16
申请号：US10995959
申请日：2004-11-23
申请人： Arbogast Grunau, , Thomas Bertelshofer , Eduard Kratz , Christian Schafer , Harald Schafer , Dietmar Jager , Marco Orsi
发明人： Arbogast Grunau, , Thomas Bertelshofer , Eduard Kratz , Christian Schafer , Harald Schafer , Dietmar Jager , Marco Orsi
CPC分类号： F16H7/0848 , F16H2007/0806 , F16H2007/0859
摘要： A tensioner for a traction drive includes a cylinder arranged in a housing at a distance to a housing wall to thereby define an interior space which contains hydraulic fluid. A piston is received in the cylinder for back-and-forth movement and bounds a pressure chamber containing hydraulic fluid. The piston has a cylinder-distal end which is operatively connected to a spring-biased tension roller supported on a traction member. Formed between the piston and the cylinder is a leakage gap, and a reservoir for hydraulic fluid is provided in an area of the leakage gap to prevent ingress of air into the pressure chamber, when the traction drive is at a rest.
摘要翻译： 用于牵引驱动器的张紧器包括布置在与壳体壁一定距离的壳体中的气缸，从而限定包含液压流体的内部空间。 活塞被容纳在气缸中用于往复运动，并且限定了包含液压流体的压力室。 活塞具有气缸 - 远端，其可操作地连接到支撑在牵引构件上的弹簧偏压张力辊。 在活塞和气缸之间形成有泄漏间隙，并且在牵引驱动器处于静止状态时，在泄漏间隙的区域中设置用于液压流体的储存器，以防止空气进入压力室。
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公开(公告)号：US20100069510A1
公开(公告)日：2010-03-18
申请号：US12528841
申请日：2008-03-04
申请人： Christian Schafer , David Schaffner
发明人： Christian Schafer , David Schaffner
CPC分类号： A23L1/2753 , A23D7/0053 , A23K20/158 , A23K20/174 , A23K20/179 , A23L2/58 , A23L5/44 , A23L33/105 , A23P10/40 , A23P10/47 , A23V2002/00 , A61K9/146 , C09B67/0092 , A23V2200/044 , A23V2200/30 , A23V2250/211 , A23V2250/5118 , A23V2250/213
摘要： The present invention relates to a process for the manufacture of an emulsion or dispersion containing one or more carotenoids, in a preferred embodiment it relates to the manufacture of a powder containing one or more carotenoids, furthermore to the powder obtainable by said process and a food composition, especially a beverage, containing said powder.
摘要翻译： 本发明涉及一种制备含有一种或多种类胡萝卜素的乳液或分散体的方法，在优选的实施方案中，其涉及制备含有一种或多种类胡萝卜素的粉末，此外还涉及可通过所述方法获得的粉末和食物 组合物，特别是含有所述粉末的饮料。
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公开(公告)号：US20080087244A1
公开(公告)日：2008-04-17
申请号：US11904693
申请日：2007-09-28
IPC分类号： F01L1/245
CPC分类号： F01L13/0031 , F01L1/24 , F01L1/245 , F01L2101/00 , F01L2101/02
摘要： A hydraulic valve lash adjuster with idle stroke function for a valve train of an internal combustion engine, said hydraulic valve lash adjuster comprising a piston (2, 2′, 2″) that is guided for displacement in a piston housing (4) and elastically supported against said housing (4), said piston (2, 2′, 2″) comprising a low pressure chamber (3) that communicates via an axial opening (7) in a piston bottom (8) with a high pressure chamber (5) defined by the piston housing (4) and the piston (2, 2′, 2″), and further comprising a control valve (9, 9′, 9″, 9′″) acting between said pressure chambers (3, 5), said control valve (9, 9′, 9″, 9′″) comprising a valve closing body (10, 10′, 10″) that can be brought to bear sealingly against a valve seat (15, 15′) that surrounds the axial opening (7) on a piston body undersurface (18) and is received in an element (12, 12′) that limits a closing body stroke (17), and said control valve (9, 9′, 9″, 9′″) further comprising a control valve spring (11) that loads the valve closing body (10, 10′, 10″) with a spring force in opening direction, and an idle stroke being produced during a collapsing movement between the piston (2, 2′, 2″) and the piston housing (4) during which said valve closing body (10, 10′, 10″) is hydraulically loaded in closing direction against the action of the control valve spring (11) by a pressure build-up in the high pressure chamber (5), whereby a retarded pressure build-up can be obtained through a flow control device (23, 23′) arranged on a high pressure chamber-side and comprising a flow control element (24, 24′) and a medium pressure chamber (19) that extends between the flow control element (24, 24′) and the axial opening (7) of the piston (2).
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