-
公开(公告)号：US4948816A
公开(公告)日：1990-08-14
申请号：US368558
申请日：1989-06-20
IPC分类号： G01N33/48 , A61K8/00 , A61K8/04 , A61K8/30 , A61K8/64 , A61K8/72 , A61K8/88 , A61Q1/00 , A61Q1/02 , A61Q1/12 , B01D15/08 , B01J20/26 , B01J20/281 , C08G69/00 , C08G69/08 , C08G69/10 , C08J3/14 , G01N30/88
CPC分类号： A61K8/025 , A61K8/88 , A61Q1/12 , B01J20/26 , B01J20/285 , C08G69/08 , C08J3/14 , A61K2800/412 , C08J2377/00
摘要： The present invention provides novel spherical grains of polyamino acid wh can be used as a filler in chromatography, cosmetic powder and the like. The spherical grains can be produced by a method which comprises the steps of preparing a solution of hydrophobic polyamino acid such as poly n-leucine dissolved in an organic solvent; adding the solution to an aqueous medium and agitating said medium so as to obtain a dispersion of the spherical grains of the polyamino acid dispersed in the aqueous medium while evaporating the organic solvent; and taking out the spherical grains of polyamino acid from the dispersion.
-
2.发明授权公开(公告)号：US07563580B2
公开(公告)日：2009-07-21
申请号：US12071891
申请日：2008-02-27
CPC分类号： B01J20/28033 , B01D15/00 , B01D15/08 , B01D15/305 , B01D15/327 , B01J20/261 , B01J20/264 , B01J20/28004 , B01J20/28019 , B01J20/286 , B01J20/3212 , B01J20/3219 , B01J20/3255 , B01J20/327 , B01J20/3425 , B01J20/3475 , B01J2220/54 , B01J2220/58 , C07H21/04 , C12Q1/6806 , C12Q2527/125 , C12Q2523/308
摘要： A nucleic acid adsorbent in which a polymer having a constitutional unit represented by the following formula (I) is immobilized on a water-insoluble carrier is used as a nucleic acid adsorbent capable of selectively and efficiently adsorbing nucleic acids from complex mixtures, such as cell extract, wherein R1 represents hydrogen, fluoride, or methyl; R2 and R3 each independently represent alkyl of 1 to 6 carbon atoms; A is —NH— or —O—; and B represents alkylene of 2 to 18 carbon atoms. Nucleic acids are recovered from cell extract by allowing them to be adsorbed to the nucleic acid adsorbent by mixing this nucleic acid adsorbent with cell extract, removing the nucleic acids from the cell extract by separating the adsorbent therefrom, and dissociating the nucleic acids from the nucleic acid adsorbent by treating the separated nucleic acid adsorbent with alkali.
摘要翻译： 将其中具有由下式（I）表示的结构单元的聚合物固定在水不溶性载体上的核酸吸附剂用作能够选择性和有效地从复杂混合物如细胞中吸附核酸的核酸吸附剂 提取物，其中R1表示氢，氟化物或甲基; R2和R3各自独立地表示1〜6个碳原子的烷基; A是-NH-或-O-; B表示2〜18个碳原子的亚烷基。 从细胞提取物中回收核酸，使其通过将该核酸吸附剂与细胞提取物混合而被吸附到核酸吸附剂，通过从其中分离吸附剂从细胞提取物中除去核酸，以及从核酸解离核酸 通过用碱处理分离的核酸吸附剂的酸吸附剂。
-
3.发明申请公开(公告)号：US20080227969A1
公开(公告)日：2008-09-18
申请号：US12071891
申请日：2008-02-27
IPC分类号： C07H21/00
CPC分类号： B01J20/28033 , B01D15/00 , B01D15/08 , B01D15/305 , B01D15/327 , B01J20/261 , B01J20/264 , B01J20/28004 , B01J20/28019 , B01J20/286 , B01J20/3212 , B01J20/3219 , B01J20/3255 , B01J20/327 , B01J20/3425 , B01J20/3475 , B01J2220/54 , B01J2220/58 , C07H21/04 , C12Q1/6806 , C12Q2527/125 , C12Q2523/308
摘要： A nucleic acid adsorbent in which a polymer having a constitutional unit represented by the following formula (I) is immobilized on a water-insoluble carrier is used as a nucleic acid adsorbent capable of selectively and efficiently adsorbing nucleic acids from complex mixtures, such as cell extract, wherein R1 represents hydrogen, fluoride, or methyl; R2 and R3 each independently represent alkyl of 1 to 6 carbon atoms; A is —NH— or —O—; and B represents alkylene of 2 to 18 carbon atoms. Nucleic acids are recovered from cell extract by allowing them to be adsorbed to the nucleic acid adsorbent by mixing this nucleic acid adsorbent with cell extract, removing the nucleic acids from the cell extract by separating the adsorbent therefrom, and dissociating the nucleic acids from the nucleic acid adsorbent by treating the separated nucleic acid adsorbent with alkali.
摘要翻译： 将其中具有由下式（I）表示的结构单元的聚合物固定在水不溶性载体上的核酸吸附剂用作能够选择性和有效地从复杂混合物如细胞中吸附核酸的核酸吸附剂 提取物，其中R 1代表氢，氟化物或甲基; R 2和R 3各自独立地表示1至6个碳原子的烷基; A是-NH-或-O-; B表示2〜18个碳原子的亚烷基。 从细胞提取物中回收核酸，使其通过将该核酸吸附剂与细胞提取物混合而被吸附到核酸吸附剂，通过从其中分离吸附剂从细胞提取物中除去核酸，以及从核酸解离核酸 通过用碱处理分离的核酸吸附剂的酸吸附剂。
-
公开(公告)号：US5401499A
公开(公告)日：1995-03-28
申请号：US015833
申请日：1993-02-10
申请人： Chuichi Hirayama , Keijun Hiraoka , Sunao Morimoto
发明人： Chuichi Hirayama , Keijun Hiraoka , Sunao Morimoto
IPC分类号： A61K9/08 , B01J20/22 , B01J20/26 , B01J20/28 , B01D15/08 , A61K31/785 , B01D39/16 , B01D39/18
CPC分类号： B01J20/28045 , B01J20/22 , B01J20/28014 , B01J20/28016 , B01J20/28021 , B01J20/28023 , B01J20/28033 , B01J20/28042 , Y10S428/902 , Y10S428/903 , Y10T428/13 , Y10T428/1303 , Y10T428/1307 , Y10T428/19 , Y10T428/2913 , Y10T442/3146 , Y10T442/637
摘要： An insoluble material for adsorbing a pyrogen comprising a polymer of an aziridine compound. According to the present invention, a large mount of the pyrogen can be easily removed from a solution containing pyrogen, and a large amount of the material for adsporbing the pyrogen can be prepared in easy steps. Therefore, the adsorbing material can greatly contribute to the preparation of medicines.
摘要翻译： 用于吸附含有氮丙啶化合物的聚合物的热原的不溶物质。 根据本发明，可以容易地从含有热原的溶液中除去大量的热原，并且可以容易地制备大量用于放射热原的材料。 因此，吸附材料可大大有助于药物的制备。
-
公开(公告)号：US5059542A
公开(公告)日：1991-10-22
申请号：US420531
申请日：1989-10-12
IPC分类号： G01N33/544 , A61K9/16 , C08B37/00 , C08F8/28 , G01N33/543 , G01N33/548
CPC分类号： A61K9/1641 , A61K9/1652 , C08G69/36 , G01N33/54313
摘要： An artificial carrier particle comprising an anionic polymer and a synthetic polyamino acid having at least one carboxylic group and at least one amino group in its side chain, the complex being insolubilized by an aldehyde crosslinking agent. The artificial carrier particle is useful in immunoassay, in particular, particle immunoassay. The artificial carrier particles are obtained by preparing an aqueous solution containing an anionic polymer and a synthetic polyamino acid comprising at least one free carboxyl group and at least one free amino group in its side chain, adjusting the pH of the solution to 3.5 to 9.5 at room temperature or at progressively increasing temperature under stirring to form solution particles of a desired particle size, and insolubilizing the particles by an aldehyde crosslinking agent.
-
公开(公告)号：US07358050B2
公开(公告)日：2008-04-15
申请号：US11214773
申请日：2005-08-31
CPC分类号： B01J20/28033 , B01D15/00 , B01D15/08 , B01D15/305 , B01D15/327 , B01J20/261 , B01J20/264 , B01J20/28004 , B01J20/28019 , B01J20/286 , B01J20/3212 , B01J20/3219 , B01J20/3255 , B01J20/327 , B01J20/3425 , B01J20/3475 , B01J2220/54 , B01J2220/58 , C07H21/04 , C12Q1/6806 , C12Q2527/125 , C12Q2523/308
摘要： A nucleic acid adsorbent in which a polymer having a constitutional unit represented by the following formula (I) is immobilized on a water-insoluble carrier is used as a nucleic acid adsorbent capable of selectively and efficiently adsorbing nucleic acids from complex mixtures, such as cell extract, wherein R1 represents hydrogen, fluoride, or methyl; R2 and R3 each independently represent alkyl of 1 to 6 carbon atoms; A is —NH— or —O—; and B represents alkylene of 2 to 18 carbon atoms. Nucleic acids are recovered from cell extract by allowing them to be adsorbed to the nucleic acid adsorbent by mixing this nucleic acid adsorbent with cell extract, removing the nucleic acids from the cell extract by separating the adsorbent therefrom, and dissociating the nucleic acids from the nucleic acid adsorbent by treating the separated nucleic acid adsorbent with alkali.
-
7.发明授权公开(公告)号：US06699386B2
公开(公告)日：2004-03-02
申请号：US10085005
申请日：2002-03-01
IPC分类号： B01D1508
CPC分类号： B01J20/24 , B01J20/26 , B01J20/262 , B01J20/265 , B01J20/3212 , B01J20/3217 , B01J20/3219 , B01J20/3255 , B01J20/3272
摘要： This invention provides an adsorbent having a high ability to adsorb endotoxin selectively and a method of adsorbing endotoxin. The adsorbent comprises a basic substance bonded to a base material by means of a crosslinking agent.
摘要翻译： 本发明提供具有高选择性吸附内毒素能力的吸附剂和吸附内毒素的方法。 吸附剂包括通过交联剂与基材结合的碱性物质。
-
公开(公告)号：US4975542A
公开(公告)日：1990-12-04
申请号：US354025
申请日：1989-05-19
申请人： Chuichi Hirayama , Hirotaka Ihara , Junichi Ida
发明人： Chuichi Hirayama , Hirotaka Ihara , Junichi Ida
CPC分类号： C08J3/14 , B01J20/24 , C08B37/003 , C08J2305/08
摘要： A method for preparing granular porous chitosan which comprises dispersing an acidic aqueous solution of chitosan in a hydrophobic dispersing medium; and, evaporating water off while stirring the resulting dispersion.
-
公开(公告)号：US4840975A
公开(公告)日：1989-06-20
申请号：US117925
申请日：1987-11-03
IPC分类号： G01N33/48 , A61K8/00 , A61K8/04 , A61K8/30 , A61K8/64 , A61K8/72 , A61K8/88 , A61Q1/00 , A61Q1/02 , A61Q1/12 , B01D15/08 , B01J20/26 , B01J20/281 , C08G69/00 , C08G69/08 , C08G69/10 , C08J3/14 , G01N30/88
CPC分类号： A61K8/025 , A61K8/88 , A61Q1/12 , B01J20/26 , B01J20/285 , C08G69/08 , C08J3/14 , A61K2800/412 , C08J2377/00
摘要： The present invention provides novel spherical grains of polyamino acid wh can be used as a filler in chromatography, cosmetic powder and the like. The spherical grains can be produced by a method which comprises the steps of preparing a solution of hydrophobic polyamino acid such as poly n-leucine dissolved in an organic solvent; adding the solution to an aqueous medium and agitating said medium so as to obtain a dispersion of the spherical grains of the polyamino acid dispersed in the aqueous medium while evaporating the organic solvent; and taking out the spherical grains of polyamino acid from the dispersion.
摘要翻译： 本发明提供了可用作色谱法，化妆粉等中的填充剂的新型聚氨基酸球形颗粒。 可以通过包括以下步骤制备球形颗粒的方法：制备溶解在有机溶剂中的聚n-亮氨酸等疏水性聚氨基酸溶液; 将溶液加入到水性介质中并搅拌所述介质，以便在蒸发有机溶剂的同时获得分散在水性介质中的聚氨基酸的球形颗粒的分散体; 并从分散体中取出聚氨基酸的球形颗粒。
-
10.发明申请公开(公告)号：US20060073499A1
公开(公告)日：2006-04-06
申请号：US11214773
申请日：2005-08-31
CPC分类号： B01J20/28033 , B01D15/00 , B01D15/08 , B01D15/305 , B01D15/327 , B01J20/261 , B01J20/264 , B01J20/28004 , B01J20/28019 , B01J20/286 , B01J20/3212 , B01J20/3219 , B01J20/3255 , B01J20/327 , B01J20/3425 , B01J20/3475 , B01J2220/54 , B01J2220/58 , C07H21/04 , C12Q1/6806 , C12Q2527/125 , C12Q2523/308
摘要： A nucleic acid adsorbent in which a polymer having a constitutional unit represented by the following formula (I) is immobilized on a water-insoluble carrier is used as a nucleic acid adsorbent capable of selectively and efficiently adsorbing nucleic acids from complex mixtures, such as cell extract, wherein R1 represents hydrogen, fluoride, or methyl; R2 and R3 each independently represent alkyl of 1 to 6 carbon atoms; A is —NH— or —O—; and B represents alkylene of 2 to 18 carbon atoms. Nucleic acids are recovered from cell extract by allowing them to be adsorbed to the nucleic acid adsorbent by mixing this nucleic acid adsorbent with cell extract, removing the nucleic acids from the cell extract by separating the adsorbent therefrom, and dissociating the nucleic acids from the nucleic acid adsorbent by treating the separated nucleic acid adsorbent with alkali.
摘要翻译： 将其中具有由下式（I）表示的结构单元的聚合物固定在水不溶性载体上的核酸吸附剂用作能够选择性和有效地从复杂混合物如细胞中吸附核酸的核酸吸附剂 提取物，其中R 1代表氢，氟化物或甲基; R 2和R 3各自独立地表示1至6个碳原子的烷基; A是-NH-或-O-; B表示2〜18个碳原子的亚烷基。 从细胞提取物中回收核酸，使其通过将该核酸吸附剂与细胞提取物混合而被吸附到核酸吸附剂，通过从其中分离吸附剂从细胞提取物中除去核酸，以及从核酸解离核酸 通过用碱处理分离的核酸吸附剂的酸吸附剂。
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.011 秒)
