Agents for controlling biological fluids and methods of use thereof
    2.
    发明授权
    Agents for controlling biological fluids and methods of use thereof 有权
    用于控制生物流体的试剂及其使用方法

    公开(公告)号:US08535709B2

    公开(公告)日:2013-09-17

    申请号:US11452139

    申请日:2006-06-13

    IPC分类号: A61K33/14

    摘要: Therapeutic formulations adapted for positive-pressure application for controlling biological fluid at a desired site in a subject, absorbent articles comprising therapeutic formulations, and anti-infective devices coated with therapeutic formulations, said formulations comprising about 25% to about 99% by weight liquid-crystal forming compound and 0% to about 75% by weight solvent. In addition, methods of using said formulations including methods for controlling biological fluid at a desired site in a subject, methods for controlling blood loss, and methods for facilitating effective closure of a vascular wound or incision site at a desired site in a subject are disclosed, the methods comprising administering particular formulations comprising liquid-crystal forming compounds and solvents that are described herein.

    摘要翻译: 适用于正压施用以控制受试者所需部位的生物流体,包含治疗制剂的吸收制品和用治疗制剂涂覆的抗感染装置的治疗制剂,所述制剂包含约25重量%至约99重量% 结晶形成化合物和0%至约75%重量的溶剂。 此外,公开了使用所述制剂的方法,包括在受试者的期望部位控制生物流体的方法,用于控制失血的方法,以及促进受试者的期望部位的血管伤口或切口部位的有效闭塞的方法。 所述方法包括施用包含本文所述的液晶形成化合物和溶剂的特定制剂。

    Methods and Compositions for Sealing and Adhering Biological Tissues and Medical Uses Thereof
    10.
    发明申请
    Methods and Compositions for Sealing and Adhering Biological Tissues and Medical Uses Thereof 有权
    密封和粘附生物组织的方法和组合及其医疗用途

    公开(公告)号:US20100087851A1

    公开(公告)日:2010-04-08

    申请号:US12441224

    申请日:2007-09-13

    IPC分类号: A61B17/08 A61K38/40

    摘要: Compositions and methods for sealing, coating and adhering tissues are provided that utilize a polymeric system comprising at least a Polymer and a crosslinking agent; and, optionally, (i) a Gelation Disrupting Agent, (ii) an Augmentative Polymer or Monomer, (iii) an Adjunct Compound (iv) an Antimicrobial Agent (v) an Adhesion Enhancer, (vi) a Crosslink Augmentating Agent or any combination thereof. Additionally, a Therapeutic Agent may be incorporated.

    摘要翻译: 提供用于密封,涂覆和粘附组织的组合物和方法,其利用包含至少一种聚合物和交联剂的聚合体系; 和(i)凝胶破坏剂,(ii)增量聚合物或单体,(iii)辅助化合物(iv)抗微生物剂(v)粘附增强剂,(vi)交联增强剂或任何组合 其中。 另外,可以并入治疗剂。