公开(公告)号：US20190011466A1

公开(公告)日：2019-01-10

申请号：US16073742

申请日：2017-01-25

申请人： Hôpitaux Universitaires de Strasbourg ,  Diagnostica Stago

发明人： Julie BOISRAMÉ-HELMS ,  Florence TOTI ,  Laure STIEL ,  Laurent MAUVIEUX ,  Ferhat MEZIANI

IPC分类号： G01N33/86 ,  G01N15/14

摘要： Some embodiments relates to a method for predicting and/or detecting disseminated intravascular coagulation (DIC) in a biological sample, and a kit for predicting and/or detecting disseminated intravascular coagulation (DIC) in a biological sample. Some embodiments has application, in particular, in the medical and veterinary field.

公开(公告)号：US20030157582A1

公开(公告)日：2003-08-21

申请号：US10302649

申请日：2002-11-22

申请人： Societe Diagnostica-Stago

发明人： Jean-Paul Roisin ,  Stephane Steurs ,  Gerard Quentin

IPC分类号： C12Q001/56 ,  C07C066/00 ,  C07C065/03

CPC分类号： G01N33/86 ,  C07C69/757 ,  C07C69/88 ,  C07C235/50 ,  C07C235/82 ,  C08G73/02

摘要： The invention concerns contact activators for the endogenous coagulation pathway and their use in exploring coagulation anomalies. The activators of the invention are derivatives of gallic acid, preferably polyethylene glycol gallates.

摘要翻译： 本发明涉及用于内源性凝血途径的接触激活剂及其在探索凝血异常中的用途。 本发明的活化剂是没食子酸的衍生物，优选聚乙二醇没食子酸酯。

公开(公告)号：US12078645B2

公开(公告)日：2024-09-03

申请号：US16073742

申请日：2017-01-25

申请人： Hôpitaux Universitaires de Strasbourg ,  Diagnostica Stago

发明人： Julie Helms ,  Florence Toti ,  Laure Stiel ,  Laurent Mauvieux ,  Ferhat Meziani

IPC分类号： G01N33/53 ,  G01N15/14 ,  G01N33/50 ,  G01N33/68 ,  G01N33/86

CPC分类号： G01N33/86 ,  G01N15/14 ,  G01N33/5005 ,  G01N33/6893 ,  G01N2015/1486 ,  G01N2333/70503 ,  G01N2333/70596 ,  G01N2800/226 ,  G01N2800/26 ,  G01N2800/50 ,  G01N2800/52

摘要： A method and kit for-, in particular, the medical and veterinary field, predicts and/or detects disseminated intravascular coagulation (DIC) in a biological sample.

公开(公告)号：US12050230B2

公开(公告)日：2024-07-30

申请号：US18050674

申请日：2022-10-28

申请人： DIAGNOSTICA STAGO

发明人： Serge Andrade ,  Christophe Villain

IPC分类号： G01N35/04 ,  B01L3/00 ,  G01L3/00 ,  B01L9/06 ,  B60P1/00 ,  B65G47/26 ,  B65G54/02 ,  G01N1/14 ,  G01N35/00 ,  G01N35/02 ,  G06F17/00 ,  G07F11/00 ,  H05B1/00

CPC分类号： G01N35/04 ,  B01L3/50855 ,  B01L9/06 ,  B60P1/00 ,  B65G47/26 ,  B65G54/02 ,  G01N1/14 ,  G01N35/00 ,  G01N2035/00326 ,  G01N2035/00534 ,  G01N2035/00752 ,  G01N35/021 ,  G01N2035/0406 ,  G01N2035/0408 ,  G01N2035/0465 ,  G06F17/00 ,  G07F11/00 ,  H05B1/00

摘要： Automatic device for the automated conduct of analyses, notably medical analyses, including:



43. a storage zone for bottles,
44. an automated sampling system for selectively sampling the content of a bottle among those present in the storage zone,
45. a loading zone for introducing a new bottle into the automatic device,
46. an unloading zone for collecting a bottle previously present in the storage zone,
47. a bottle conveyor and storage system, configured selectively and individually to transport a bottle from a location in the storage zone to the unloading zone or from the loading zone to a location in the storage zone.

公开(公告)号：US20200038873A1

公开(公告)日：2020-02-06

申请号：US16606248

申请日：2018-04-10

申请人： DIAGNOSTICA STAGO

发明人： Matthieu BROSSARD

IPC分类号： B01L3/00 ,  B65D83/04

摘要： Disclosed is a device for packaging balls for reaction vessels for an analysis appliance, including: a body including at least one opening and used to house balls, a closing member, that can be moved relative to the body between a closed position in which the closing member closes the opening of the body, and an open position in which the opening of the body is open so as to allow the balls to be dispensed from the body.

公开(公告)号：US20190136292A1

公开(公告)日：2019-05-09

申请号：US16099889

申请日：2017-05-10

申请人： Diagnostica Stago

发明人： Sébastien Kerdelo

IPC分类号： C12Q1/56 ,  G16B20/00 ,  C12N9/90 ,  C12N9/88 ,  C12N9/14

摘要： The present invention relates to a universal calibration method of use for assaying inhibitors of the same enzyme, for example for assaying inhibitors of an enzyme of blood coagulation. The invention also relates to the use of this universal calibration in a method for assaying a reversible or irreversible inhibitor of the enzyme in a biological sample. The invention also relates to the use of the universal calibration in a method for screening inhibitors of the enzyme.

公开(公告)号：US20170234853A1

公开(公告)日：2017-08-17

申请号：US15326120

申请日：2015-07-24

申请人： DIAGNOSTICA STAGO ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS ,  UNIVERSITE GRENOBLE I JOSEPH FOURIER ,  CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE

发明人： Geneviève CONTANT ,  Benoît POLACK ,  François CATON ,  Carhel DASSI

IPC分类号： G01N33/49 ,  G01N21/31

CPC分类号： G01N33/4905 ,  G01N21/31 ,  G01N2201/12 ,  G01N2333/7454 ,  G01N2333/75 ,  G01N2800/224 ,  G01N2800/226 ,  G01N2800/50

摘要： The present invention relates to a method for dynamically determining the structural profile of a fibrin clot, reflecting the stability thereof in a biological sample of a patient. The method preferably includes a step that makes it possible to predict the risk of bleeding, thrombosis or rethrombosis and to select the anticoagulant that is best suited to the clinical situation of a patient.

公开(公告)号：US20220380833A1

公开(公告)日：2022-12-01

申请号：US17874805

申请日：2022-07-27

申请人： Diagnostica Stago

发明人： Sébastien Kerdelo

IPC分类号： C12Q1/56 ,  G16B20/00 ,  C12N9/14 ,  C12N9/88 ,  C12N9/90

摘要： The present invention relates to a universal calibration method of use for assaying inhibitors of the same enzyme, for example for assaying inhibitors of an enzyme of blood coagulation. The invention also relates to the use of this universal calibration in a method for assaying a reversible or irreversible inhibitor of the enzyme in a biological sample. The invention also relates to the use of the universal calibration in a method for screening inhibitors of the enzyme.

公开(公告)号：US11426736B2

公开(公告)日：2022-08-30

申请号：US16405138

申请日：2019-05-07

申请人： DIAGNOSTICA STAGO

发明人： Fabrice Lejay

IPC分类号： B01L9/06 ,  B01L3/00 ,  G01N35/02 ,  G01N35/04

摘要： Disclosed is a gripping device for a container intended for a biological analysis, including an annular part of X axis, elastically deformable gripping fins extending radially inwardly from the annular part, the fins being capable of being deformed when a container is introduced into the annular part, the fins being evenly distributed over the circumference. Each fin has a so-called upper surface and an opposite so-called lower surface, the lower surface being intended to come into contact with the container, the lower surface having a concave zone, or vice versa.

公开(公告)号：US10605801B2

公开(公告)日：2020-03-31

申请号：US15535696

申请日：2015-12-09

申请人： DIAGNOSTICA STAGO

发明人： Alain Rousseau ,  Norbert Brutt ,  Bertrand Guyon

IPC分类号： G01N33/49 ,  G01N11/16 ,  G01N21/59 ,  G01N11/00 ,  G01N21/82

摘要： This determination method comprises the steps consisting of providing a reaction vessel (2) containing a blood sample (33) and a ferromagnetic ball (11) placed on a raceway (9) provided in the bottom of the reaction vessel (2), subjecting the ball (11) to a magnetic field so as to move the ball along the raceway (9) in an oscillatory motion, exposing the blood sample to an incident light beam (36), detecting a light beam (38) transmitted through the reaction vessel (2) and coming from the incident light beam (36) in such a way as to provide a measurement signal, carrying out a first processing of the measurement signal in such a way as to provide a first signal representative of the variation of at least one physical quantity representative of the movement of the ball (11), carrying out a second processing of the measurement signal in such a way as to provide a second signal representative of the variation of at least one optical property of the blood sample, determining a first value of the coagulation time of the blood sample from the first signal, and determining a second value of the coagulation time of the blood sample from the second signal.