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1.发明申请LOW VOC SOLVENTBORNE DISPERSION COMPOSITIONS FOR TINTING SOLVENT-BASED COATINGS 有权适用于溶剂型涂料的低VOC溶剂挥发组分公开(公告)号：US20130237656A1
公开(公告)日：2013-09-12
申请号：US13640835
申请日：2011-04-12
CPC分类号： C08K5/10 , C08K3/013 , C08K5/101 , C09B67/001 , C09B67/0013 , C09B67/009 , C09D17/002 , C09D17/003 , C09D17/004
摘要： A solventborne pigment dispersion having a volatile organic chemical (VOC) content that is less than 250 g/L for tinting solvent-based surface coatings is formulated using a vegetable oil-derived solvent component that is one or more methyl esters of vegetable oils, an acrylic resin containing at least 60% solids, one or more highly concentrated surfactants containing up to 100% by weight of active constituents and that contains no PMA or free aromatic moieties, and one or more organic pigments or one or more inorganic pigment, or a combination thereof.
摘要翻译： 具有挥发性有机化学物质（VOC）含量低于250g / L的溶剂型颜料分散体，用于着色溶剂型表面涂层，使用植物油衍生的溶剂组分，其是植物油的一种或多种甲基酯， 含有至少60％固体的丙烯酸树脂，含有至多100重量％活性成分且不含PMA或游离芳族部分的一种或多种高度浓缩的表面活性剂和一种或多种有机颜料或一种或多种无机颜料，或 的组合。
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公开(公告)号：US20110077644A1
公开(公告)日：2011-03-31
申请号：US12892727
申请日：2010-09-28
申请人： Francis Pham , Kimbolt Young , Daniel Goldberg
发明人： Francis Pham , Kimbolt Young , Daniel Goldberg
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/00053 , A61B2018/00577 , A61B2018/143 , A61B2018/1432
摘要： The tissue ablation device includes a tissue ablation probe having an elongated probe shaft and electrodes carried by the distal end of the probe shaft. The device further comprises a cannula with a central lumen extending along a longitudinal axis for removably receiving the probe shaft. The cannula further comprises concentric inner and outer tubes extending along the longitudinal axis, wherein the outer is tube is translatable relative to the inner tube. The inner and outer tubes further comprise inner and outer apertures, respectively, that are aligned by translating the outer tube. When the inner and outer apertures are aligned, electrodes are deployed through the inner and outer apertures. One method includes introducing a cannula and a tissue ablation probe to a tissue site and operating the tissue ablation probe and the cannula to deploy the electrodes and ablate tissue.
摘要翻译： 组织消融装置包括具有细长探针轴和由探针轴的远端承载的电极的组织消融探针。 该装置还包括具有沿着纵向轴线延伸的中央腔的插管，用于可移除地接收探针轴。 套管还包括沿着纵向轴线延伸的同心的内管和外管，其中外管是可相对于内管平移的。 内管和外管还分别包括通过平移外管对准的内孔和外孔。 当内孔和外孔对准时，电极通过内孔和外孔展开。 一种方法包括将套管和组织消融探针引入组织部位并操作组织消融探针和套管来展开电极并消融组织。
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公开(公告)号：US20060276496A1
公开(公告)日：2006-12-07
申请号：US11276933
申请日：2006-03-17
申请人： Daniel Goldberg , Asitha Abeywardane , Craig Miller , Tina Morwick , Matthew Netherton , Roger Snow , Ji Wang , Jiang-Ping Wu , Zhaoming Xiong
发明人： Daniel Goldberg , Asitha Abeywardane , Craig Miller , Tina Morwick , Matthew Netherton , Roger Snow , Ji Wang , Jiang-Ping Wu , Zhaoming Xiong
IPC分类号： A61K31/4745 , A61K31/403 , C07D471/02
CPC分类号： C07D471/02
摘要： Heterocyclic compounds and analogues thereof and their use as inhibitors of Mitogen-Activated Protein Kinase-Activated Protein kinase-2 (MAPKAP-k2), and also to a method for preventing or treating a disease or disorder that can be treated or prevented by modulating the activity of MAPKAP-K2 in a subject and to pharmaceutical compositions and kits that include these MAPKAP-K2 inhibitors.
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公开(公告)号：US20060235017A1
公开(公告)日：2006-10-19
申请号：US11426603
申请日：2006-06-27
申请人： Pier Cirillo , Donghong Gao , Daniel Goldberg , Abdelhakim Hammach , Ming-Hong Hao , Victor Kamhi , Neil Moss , Matthew Netherton , Kevin Qian , Mark Ralph , Lifen Wu , Zhaoming Xiong , Ronald Aungst
发明人： Pier Cirillo , Donghong Gao , Daniel Goldberg , Abdelhakim Hammach , Ming-Hong Hao , Victor Kamhi , Neil Moss , Matthew Netherton , Kevin Qian , Mark Ralph , Lifen Wu , Zhaoming Xiong , Ronald Aungst
IPC分类号： A61K31/5377 , A61K31/513 , C07D413/14 , C07D403/14
CPC分类号： C07D401/12 , C07D403/12
摘要： Disclosed are compounds of formula (I) Where Ar1, X, Y, Q, W, R3, R4, R5, R6 and Ry are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
摘要翻译： 公开了式（I）的化合物，其中Ar 1，X，Y，Q，W，R 3，R 4，R SUP > 5，R 6和R y在本文中定义。 本发明的化合物抑制涉及炎症过程的细胞因子的产生，因此可用于治疗涉及诸如慢性炎性疾病的炎症的疾病和病理状况。 该化合物也可用于治疗与肿瘤学和抗凝血剂或纤维蛋白溶解疗法有关的疾病或病症。 还公开了制备这些化合物的方法和包含这些化合物的药物组合物。
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公开(公告)号：US20050153972A1
公开(公告)日：2005-07-14
申请号：US11002022
申请日：2004-12-01
IPC分类号： C07D249/06 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , A61K31/501 , A61K31/4192 , A61K31/4439 , C07D43/02
CPC分类号： C07D401/12 , C07D249/06 , C07D403/12 , C07D405/12 , C07D413/12
摘要： Disclosed are compounds of formula (I) Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines and are thus useful for treating cytokine mediated diseases. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
摘要翻译： 公开了式（I）的化合物，其中Ar 1，X，R 3，R 4，R 5， 和R 6'在本文中定义。 本发明的化合物抑制细胞因子的产生，因此可用于治疗细胞因子介导的疾病。 还公开了制备这些化合物的方法和包含这些化合物的药物组合物。
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公开(公告)号：US06770639B2
公开(公告)日：2004-08-03
申请号：US10292026
申请日：2002-11-12
申请人： Roger John Snow , Mario Cardozo , Daniel Goldberg , Abdelhakim Hammach , Tina Morwick , Neil Moss , Usha R. Patel , Anthony S. Prokopowicz, III , Hidenori Takahashi , Matt Aaron Tschantz , Xiao-Jun Wang
发明人： Roger John Snow , Mario Cardozo , Daniel Goldberg , Abdelhakim Hammach , Tina Morwick , Neil Moss , Usha R. Patel , Anthony S. Prokopowicz, III , Hidenori Takahashi , Matt Aaron Tschantz , Xiao-Jun Wang
IPC分类号： A61K3133
CPC分类号： C07D471/04 , C07D217/24 , C07D235/30 , C07D513/04
摘要： Disclosed are novel compounds of formula (I): wherein Ar1, Ra, R4, R5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases associated with such kinases, for example, diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer, as well as conditions resulting from cerebral ischemia, such as stroke. Also disclosed are processes for preparing these compounds, novel intermediates useful in these processes and compositions comprising compounds of the formula (I).
摘要翻译： 公开了式（I）的新化合物：其中Ar1，Ra，R4，R5，X和Y定义如下，其可用作某些蛋白酪氨酸激酶的抑制剂，因此可用于治疗与这种激酶相关的疾病，例如 由不适当的细胞增殖引起的疾病，包括自身免疫性疾病，慢性炎性疾病，过敏性疾病，移植排斥和癌症，以及脑缺血症如中风引起的疾病。 还公开了制备这些化合物的方法，可用于这些方法的新型中间体和包含式（I）化合物的组合物。
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公开(公告)号：US06506769B2
公开(公告)日：2003-01-14
申请号：US09921509
申请日：2001-08-02
申请人： Roger John Snow , Mario Cardozo , Daniel Goldberg , Abdelhakim Hammach , Tina Morwick , Neil Moss , Usha R. Patel , Anthony S. Prokopowicz, III , Hidenori Takahashi , Matt Aaron Tschantz , Xiao-Jun Wang
发明人： Roger John Snow , Mario Cardozo , Daniel Goldberg , Abdelhakim Hammach , Tina Morwick , Neil Moss , Usha R. Patel , Anthony S. Prokopowicz, III , Hidenori Takahashi , Matt Aaron Tschantz , Xiao-Jun Wang
IPC分类号： A61K314745
CPC分类号： C07D471/04 , C07D217/24 , C07D235/30 , C07D513/04
摘要： Disclosed are novel compounds of formula (I): wherein Ar1, Ra, R4, R5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases associated with such kinases, for example, diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer, as well as conditions resulting from cerebral ischemia, such as stroke. Also disclosed are processes for preparing these compounds, novel intermediates useful in these processes and compositions comprising compounds of the formula (I).
摘要翻译： 公开了式（I）的新化合物：其中Ar1，Ra，R4，R5，X和Y定义如下，其可用作某些蛋白酪氨酸激酶的抑制剂，因此可用于治疗与这种激酶相关的疾病，例如 由不适当的细胞增殖引起的疾病，包括自身免疫性疾病，慢性炎性疾病，过敏性疾病，移植排斥和癌症，以及脑缺血症如中风引起的疾病。 还公开了制备这些化合物的方法，可用于这些方法的新型中间体和包含式（I）化合物的组合物。
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公开(公告)号：US06297349B1
公开(公告)日：2001-10-02
申请号：US09486256
申请日：2000-02-24
IPC分类号： C08G6902
摘要： Condensation copolymers are disclosed which are polymerized from a first monomer which is capable of polymerization by condensation polymerization, e.g., ring opening lactone polymerization, and a second monomer which is effective to suppress the crystallization of the copolymer. It is disclosed that suppression of the crystallization can provide enhanced mechanical properties in films made from the copolymers. As a result, films prepared from the copolymers of the present invention can have properties rendering them suitable for use as biodegradable trash bags as well as for other uses.
摘要翻译： 公开了由能够通过缩聚聚合的第一单体聚合的缩合共聚物，例如开环内酯聚合，和有效抑制共聚物结晶的第二单体。 公开了抑制结晶可以在由共聚物制成的膜中提供增强的机械性能。 结果，由本发明的共聚物制备的膜可以具有使其适合用作可生物降解的垃圾袋以及用于其它用途的性质。
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公开(公告)号：US20170300647A1
公开(公告)日：2017-10-19
申请号：US15404086
申请日：2017-01-11
CPC分类号： G16H50/20 , G06F19/3456 , G06N5/045 , G06N20/00 , G06Q10/109 , G16B20/00 , G16H10/20 , G16H10/60 , G16H40/63
摘要： The invention in this application is a decision-support system that utilizes single system design (SSD) and a proprietary algorithm to determine real change is for each individual patient. It pinpoints right medication and dosage for an individual patient, targets standards for functionality, called Activities of Daily Living (ADLs), and Quality of Life Indicators (QoLIs) to maximize personal health and satisfaction. Further, the system has as hallmarks a specific communication system, provision of coordination of services and a continuum of care for seamless delivery of treatment targeted to the needs of an individual patient and his/her care network. It incorporates data collected from genomic testing, patient entry, and automated devices. It is a safety-enhancing, cost-saving, time-saving system that will address placebo effect. It will utilize a variety of technologies to gather data with flexibility for patient needs. It will utilize machine learning for added safety enhancement.
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公开(公告)号：US20170193135A1
公开(公告)日：2017-07-06
申请号：US15397235
申请日：2017-01-03
IPC分类号： G06F17/50
摘要： Described herein is a method for generating a full-scale template that allows for the precise positioning of audio and/or video (A/V) components, such as lighting, video and sound devices, onto an elongate structural member, such as a truss, in order to create a desired environment for a staged event.
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