Method, equipment and specific drawer for membrane separation utilizing concentration polarization
    3.
    发明授权
    Method, equipment and specific drawer for membrane separation utilizing concentration polarization 有权
    使用浓度极化的膜分离方法,设备和特定抽屉

    公开(公告)号:US08506812B2

    公开(公告)日:2013-08-13

    申请号:US13555668

    申请日:2012-07-23

    IPC分类号: B01D33/44 B01D29/075

    摘要: The present invention relates to a membrane separation method and a relevant equipment, in particular to a method and an equipment for membrane separation utilizing concentration polarization during membrane filtration process, especially, to a concentration process and equipment and a drawer special for drawing a concentration polarization layer. The direct removal of the concentration polarization layer from membrane surface not only decreases the adverse influence of concentration polarization on membrane separation but also obtains concentrated retention components, thereby significantly improving the ability to maintain membrane flux, solving the twinborn problems concerning concentration polarization and membrane fouling during the membrane separation process, and achieving a high-efficiency concentration for retention components. The method and equipment of the present invention can be widely applied in various membrane techniques, in particular in a membrane separation process for concentrating biomacromolecule and organic micromolecule products such as sugars, organic acids and polypeptides etc.

    摘要翻译: 本发明涉及一种膜分离方法和相关设备,特别涉及在膜过滤过程中利用浓度极化的膜分离方法和设备,特别涉及浓缩过程和设备以及特别用于绘制浓缩极化的抽屉 层。 从膜表面直接除去浓缩极化层不仅降低了浓度极化对膜分离的不利影响,而且获得了浓缩的保留成分,从而显着提高了保持膜通量的能力,解决了浓度极化和膜污染的双胎问题 在膜分离过程中,并且实现保留成分的高效浓缩。 本发明的方法和设备可以广泛地应用于各种膜技术中,特别是在用于浓缩生物大分子和有机小分子产物如糖,有机酸和多肽等的膜分离方法中。

    Anhydrous Antiperspirant Compositions
    5.
    发明申请
    Anhydrous Antiperspirant Compositions 审中-公开
    无水止汗剂组合物

    公开(公告)号:US20100104517A1

    公开(公告)日:2010-04-29

    申请号:US12603605

    申请日:2009-10-22

    申请人: Yan-fei Shen

    发明人: Yan-fei Shen

    IPC分类号: A61K9/12

    摘要: An anhydrous aerosol antiperspirant composition comprising a concentrate comprising at least about 40%, by weight of the concentrate, of an alcohol; an antiperspirant active dissolved in the alcohol; and at least one volatile silicone oil that is miscible in the alcohol and antiperspirant active solution and that has a viscosity of less than 10 centistokes at 25° C.

    摘要翻译: 一种无水气溶胶止汗组合物,其包含浓缩物,其包含至少约40重量%的浓缩物,醇; 溶于酒精的止汗剂; 和至少一种在醇和止汗活性溶液中可混溶并且在25℃下粘度小于10厘沲的挥发性硅油。

    Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists
    8.
    发明授权
    Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists 失效
    使用低剂量的阿片受体拮抗剂治疗肠易激综合征的方法和组合物

    公开(公告)号:US06737400B2

    公开(公告)日:2004-05-18

    申请号:US10114909

    申请日:2002-04-03

    IPC分类号: A61K3800

    CPC分类号: A61K31/485 A61K31/00

    摘要: This invention relates to a method for treating a subject with irritable bowel syndrome (“IBS”) which comprises long-term administration of an opioid receptor antagonist at an appropriately low dose which will selectively antagonize excitatory opioid receptor functions, but not inhibitory opioid receptor functions, in myenteric neurons in the intestinal tract as well as in neurons of the central nervous system (“CNS”). The administration of the opioid receptor antagonist at a low dose enhances the potency of the inhibitory effects of endogenous opioid peptides present in the intestinal tract and the CNS, thereby reducing abdominal pain and stool frequency resulting from abnormally supersensitized excitatory opioid receptor functions. The invention also relates to a composition for treating a subject with IBS, which comprises an effective dose of an opioid receptor antagonist, and a pharmaceutically acceptable carrier.

    摘要翻译: 本发明涉及用于治疗肠易激综合征(“IBS”)的受试者的方法,其包括以适当低剂量长期施用阿片受体拮抗剂,其将选择性拮抗兴奋性阿片受体功能,但不抑制阿片受体功能 ,在肠道的肠系膜神经元以及中枢神经系统的神经元(“CNS”)中。 以低剂量施用阿片样物质受体拮抗剂增强了存在于肠道和CNS中的内源性阿片样物质肽的抑制作用的效力,从而降低了由异常超敏刺激性阿片受体功能引起的腹痛和大便频率。 本发明还涉及用IBS治疗受试者的组合物,其包含有效剂量的阿片受体拮抗剂和药学上可接受的载体。

    Use of excitatory opioid receptor antagonists to prevent growth
factor-induced hyperalgesia
    10.
    发明授权
    Use of excitatory opioid receptor antagonists to prevent growth factor-induced hyperalgesia 失效
    兴奋性阿片样物质受体拮抗剂用于预防生长因子诱导的痛觉过敏

    公开(公告)号:US5585348A

    公开(公告)日:1996-12-17

    申请号:US106401

    申请日:1993-08-13

    摘要: This invention relates to a method of preventing hyperalgesia and other undesirable side-effects associated with the administration of growth factor, including nerve growth factor, utilizing an antagonist capable of inactivating excitatory opioid receptor-mediated functions on neurons in the nociceptive pathway. In addition, this invention relates to a composition comprising a growth factor and an antagonist capable of inactivating excitatory opioid receptor-mediated functions on neurons in the nociceptive pathway.

    摘要翻译: 本发明涉及一种利用能够使兴奋性阿片样物质受体介导的功能在伤害感受途径中的神经元上失活的拮抗剂来预防痛觉过敏和与施用生长因子(包括神经生长因子)相关的其它不期望的副作用的方法。 此外,本发明涉及一种组合物,其包含生长因子和能够灭活兴奋性阿片样物质受体介导的伤害感受途径神经元功能的拮抗剂。