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    Electrochemical apparatus comprising modified disposable rectangular cuvette
    2.
    发明授权
    Electrochemical apparatus comprising modified disposable rectangular cuvette 有权
    电化学装置，包括改进的一次性长方形比色皿

    公开(公告)号：US08529740B2

    公开(公告)日：2013-09-10

    申请号：US12916085

    申请日：2010-10-29

    Applicant: Andrew M Dattelbaum ,  Gautam Gupta ,  David E Morris

    Inventor： Andrew M Dattelbaum ,  Gautam Gupta ,  David E Morris

    IPC: G01N27/403

    CPC classification number: G01N27/27

    Abstract: Electrochemical apparatus includes a disposable rectangular cuvette modified with at least one hole through a side and/or the bottom. Apparatus may include more than one cuvette, which in practice is a disposable rectangular glass or plastic cuvette modified by drilling the hole(s) through. The apparatus include two plates and some means of fastening one plate to the other. The apparatus may be interfaced with a fiber optic or microscope objective, and a spectrometer for spectroscopic studies. The apparatus are suitable for a variety of electrochemical experiments, including surface electrochemistry, bulk electrolysis, and flow cell experiments.

    Abstract translation: 电化学装置包括经由侧面和/或底部至少一个孔改性的一次性矩形试管。 设备可以包括多于一个的比色皿，其实际上是通过钻孔来改造的一次性矩形玻璃或塑料比色皿。 该装置包括两个板和一个将一个板固定到另一个板的装置。 该装置可以与光纤或显微镜物镜和用于光谱研究的光谱仪接口。 该设备适用于各种电化学实验，包括表面电化学，体积电解和流动池实验。

    Surgical Ligature Instrument for Minimally Invasive Surgery
    4.
    发明公开
    Surgical Ligature Instrument for Minimally Invasive Surgery 审中-公开

    公开(公告)号：US20240074746A1

    公开(公告)日：2024-03-07

    申请号：US18499002

    申请日：2023-10-31

    Applicant: Abhijit Shaligram ,  Ravi Mohanka ,  Manish Mohanka ,  Gautam Gupta

    Inventor： Abhijit Shaligram ,  Ravi Mohanka ,  Manish Mohanka ,  Gautam Gupta

    IPC: A61B17/04

    CPC classification number: A61B17/0467 ,  A61B2017/00367 ,  A61B2017/0474

    Abstract: The present invention is a surgical suturing device that assists in applying an open-looped, pre-knotted suture around a targeted area of application. The surgical suturing device contains a handle, a grasping mechanism, a clamp tube, a pusher tube, a cutter tube, and a pivot arm. A first coupler is positioned on the pivot arm. A second coupler is positioned at the end of the shaft, offset from the pivot arm. A suture knot is fitted over the second coupler, and a strand is connected to the first coupler. When activated, the pivot arm moves into a closed position, thereby encircling the suturing portion and joining the first coupler to the second coupler. Next, the suture knot is pushed forward off the second coupler and tightened up against the suturing portion. The pusher tube slides back, allowing the cutter tube to cut the excess suture cord.

    Bio-compatible hybrid organic/inorganic gels: vapor phase synthesis
    5.
    发明授权
    Bio-compatible hybrid organic/inorganic gels: vapor phase synthesis 有权
    生物相容性混合有机/无机凝胶：气相合成

    公开(公告)号：US08252607B2

    公开(公告)日：2012-08-28

    申请号：US12134874

    申请日：2008-06-06

    Applicant: Gautam Gupta ,  Gabriel Lopez ,  Plamen Atanassov

    Inventor： Gautam Gupta ,  Gabriel Lopez ,  Plamen Atanassov

    IPC: G01N33/552

    CPC classification number: A61K9/06 ,  A61K9/127 ,  Y10T428/265 ,  Y10T436/25

    Abstract: The disclosure provides a simple and effective way of synthesizing robust organic-inorganic hybrid gels and ultra-thin films using vaporization of a gel precursor. The gels are synthesized at relatively low temperature allowing the activity of the immobilized species to be maintained. The disclosure provides robust, synthetic, selective, active and/or passive transport systems in the form of functional biologically active species and mechanisms for forming them. These systems allow selective and passive or active transport of ionic, molecular and biological species through the incorporation of functional biological molecules and biomolecular assemblies in a rigid matrix.

    Abstract translation: 本公开提供了使用凝胶前体的蒸发来合成鲁棒的有机 - 无机杂化凝胶和超薄膜的简单而有效的方法。 凝胶在相对较低的温度下合成，允许保持固定化物质的活性。 本公开提供了功能性生物活性物质形式的强大的，合成的，选择性的，主动的和/或被动的运输系统和用于形成它们的机制。 这些系统通过将功能性生物分子和生物分子组装结合到刚性基质中来允许离子，分子和生物物质的选择性和被动或主动传递。

    ELECTROCHEMICAL APPARATUS COMPRISING MODIFIED DISPOSABLE RECTANGULAR CUVETTE
    6.
    发明申请
    ELECTROCHEMICAL APPARATUS COMPRISING MODIFIED DISPOSABLE RECTANGULAR CUVETTE 有权
    电化学装置包括改性的可切割的矩形孔

    公开(公告)号：US20120103807A1

    公开(公告)日：2012-05-03

    申请号：US12916085

    申请日：2010-10-29

    Applicant: Andrew M. Dattelbaum ,  Gautam Gupta ,  David E. Morris

    Inventor： Andrew M. Dattelbaum ,  Gautam Gupta ,  David E. Morris

    IPC: G01N27/416 ,  G01N27/403

    CPC classification number: G01N27/27

    Abstract: Electrochemical apparatus includes a disposable rectangular cuvette modified with at least one hole through a side and/or the bottom. Apparatus may include more than one cuvette, which in practice is a disposable rectangular glass or plastic cuvette modified by drilling the hole(s) through. The apparatus include two plates and some means of fastening one plate to the other. The apparatus may be interfaced with a fiber optic or microscope objective, and a spectrometer for spectroscopic studies. The apparatus are suitable for a variety of electrochemical experiments, including surface electrochemistry, bulk electrolysis, and flow cell experiments.

    Abstract translation: 电化学装置包括经由侧面和/或底部至少一个孔改性的一次性矩形试管。 设备可以包括多于一个的比色皿，其实际上是通过钻孔来改造的一次性矩形玻璃或塑料比色皿。 该装置包括两个板和一个将一个板固定到另一个板的装置。 该装置可以与光纤或显微镜物镜和用于光谱研究的光谱仪接口。 该设备适用于各种电化学实验，包括表面电化学，体积电解和流动池实验。

    METHODS FOR COATING IMPLANTS
    8.
    发明申请
    METHODS FOR COATING IMPLANTS 审中-公开
    涂层的方法

    公开(公告)号：US20110143127A1

    公开(公告)日：2011-06-16

    申请号：US12636379

    申请日：2009-12-11

    Applicant: Gautam Gupta ,  Mukesh Kumar ,  Robert M. Ronk

    Inventor： Gautam Gupta ,  Mukesh Kumar ,  Robert M. Ronk

    IPC: B32B15/04 ,  C23C28/00 ,  B05D1/08 ,  C23C4/08 ,  C23C16/00

    CPC classification number: A61L27/32 ,  A61L27/30 ,  A61L27/306 ,  A61L27/3604 ,  A61L27/365 ,  A61L27/54 ,  A61L2420/02 ,  A61L2420/08 ,  Y10T428/265

    Abstract: An implant and method for applying an osteoconductive coating on a non-conductive surface of an implant. The method includes depositing an electroconductive interlayer on at least a portion of a non-conductive implant surface. A secondary process is applied to the interlayer and an osteoconductive coating is thereby formed on the implant. In various embodiments, the electroconductive interlayer is deposited as a non-structural film and comprises a dense, non-porous metal such as titanium, titanium alloys, cobalt, cobalt alloys, chromium, chromium alloys, tantalum, tantalum alloys, iron alloys, stainless steel, and mixtures thereof. The osteoconductive coating may include a metal, a porous metal, or calcium phosphate. The osteoconductive coating may include additional agents, such as bone product, growth factor, bioactive agent, antibiotic, or combinations thereof.

    Abstract translation: 用于在植入物的非导电表面上施加骨传导性涂层的植入物和方法。 该方法包括在非导电植入物表面的至少一部分上沉积导电中间层。 将二次方法应用于中间层，由此在植入物上形成骨传导性涂层。 在各种实施方案中，导电中间层作为非结构膜沉积并且包含致密的非多孔金属如钛，钛合金，钴，钴合金，铬，铬合金，钽，钽合金，铁合金，不锈钢 钢及其混合物。 骨传导性涂层可以包括金属，多孔金属或磷酸钙。 骨传导性涂层可以包括另外的试剂，例如骨产品，生长因子，生物活性剂，抗生素或其组合。

    METHODS OF DEPOSITING DISCRETE HYDROXYAPATITE REGIONS ON MEDICAL IMPLANTS
    9.
    发明申请
    METHODS OF DEPOSITING DISCRETE HYDROXYAPATITE REGIONS ON MEDICAL IMPLANTS 审中-公开
    沉积在医用植入物上的离子羟化酶区域的方法

    公开(公告)号：US20110089041A1

    公开(公告)日：2011-04-21

    申请号：US12581483

    申请日：2009-10-19

    Applicant: Gautam GUPTA ,  Andreas Sewing

    Inventor： Gautam GUPTA ,  Andreas Sewing

    IPC: C25D5/54 ,  C25D9/04 ,  C25D5/34

    CPC classification number: C25D9/08 ,  C25D5/18 ,  C25D5/48

    Abstract: A method for electrochemically depositing discrete regions of calcium phosphate onto a medical implant. The method includes providing an implant including at least one area having a metallic surface. At least a portion of the metallic surface is contacted with an electrolyte solution comprising calcium ions and phosphate ions. The metallic surface is used as a cathode, and an electrical potential is applied between the cathode and the electrolyte solution. The electrical potential is applied with a constant current density of from about 10 to about 50 mA/cm2 for a period of time of from about 1 to about 20 minutes. A plurality of discrete regions of needle-shaped hydroxyapatite crystals are electrochemically deposited onto the metallic surface.

    Abstract translation: 电化学沉积磷酸钙离散区域到医用植入物上的方法。 该方法包括提供包括具有金属表面的至少一个区域的植入物。 金属表面的至少一部分与包含钙离子和磷酸根离子的电解质溶液接触。 金属表面用作阴极，并且在阴极和电解质溶液之间施加电势。 以约10至约50mA / cm 2的恒定电流密度施加电位约1至约20分钟的时间。 针状羟基磷灰石晶体的多个离散区域电化学沉积在金属表面上。

    Bio-Compatible Hybrid Organic/Inorganic Gels: Vapor Phase Synthesis
    10.
    发明申请
    Bio-Compatible Hybrid Organic/Inorganic Gels: Vapor Phase Synthesis 有权
    生物相容性杂交有机/无机凝胶：气相合成

    公开(公告)号：US20080311391A1

    公开(公告)日：2008-12-18

    申请号：US12134874

    申请日：2008-06-06

    Applicant: Gautam Gupta ,  Gabriel Lopez ,  Plamen Atanassov

    Inventor： Gautam Gupta ,  Gabriel Lopez ,  Plamen Atanassov

    IPC: B32B9/00 ,  B05D3/12

    CPC classification number: A61K9/06 ,  A61K9/127 ,  Y10T428/265 ,  Y10T436/25

    Abstract: The disclosure provides a simple and effective way of synthesizing robust organic-inorganic hybrid gels and ultra-thin films using vaporization of a gel precursor. The gels are synthesized at relatively low temperature allowing the activity of the immobilized species to be maintained. The disclosure provides robust, synthetic, selective, active and/or passive transport systems in the form of functional biologically active species and mechanisms for forming them. These systems allow selective and passive or active transport of ionic, molecular and biological species through the incorporation of functional biological molecules and biomolecular assemblies in a rigid matrix.

    Abstract translation: 本公开提供了使用凝胶前体的蒸发来合成鲁棒的有机 - 无机杂化凝胶和超薄膜的简单而有效的方法。 凝胶在相对较低的温度下合成，允许保持固定化物质的活性。 本公开提供了功能性生物活性物质形式的强大的，合成的，选择性的，主动的和/或被动的运输系统和用于形成它们的机制。 这些系统通过将功能性生物分子和生物分子组装结合到刚性基质中来允许离子，分子和生物物质的选择性和被动或主动传递。

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