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    Coated polymer article and its use
    8.
    发明授权
    Coated polymer article and its use 有权
    涂层聚合物制品及其用途

    公开(公告)号：US06420028B1

    公开(公告)日：2002-07-16

    申请号：US09446672

    申请日：1999-12-22

    Applicant: Steinar Hagen ,  Rune Ringberg ,  Geir Fonnum

    Inventor： Steinar Hagen ,  Rune Ringberg ,  Geir Fonnum

    IPC: B32B516

    CPC classification number: B01J20/287 ,  B01J20/267 ,  B01J20/3208 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3251 ,  B01J2220/54 ,  Y10T428/2991 ,  Y10T428/2998 ,  Y10T428/31913 ,  Y10T428/31928

    Abstract: A polymer article having structure (I), where P comprises the basic polymer and groups —L—CH(—X(R1)p)—CH2(—Y(R2)p); L is a part of a pending group utilized for introducing —X(R1)p and —Y(R2)p; X and Y are halogen, N, S and O; R1 is hydrogen, alkyl, acyl or R2 when X is N, O or S; R2 is hydrogen, alkyl, alkylaryl or arylalkyl in which the alkyl part may contain 1-18 carbons, or —R3(—NH—CR4═O)q or —R3(—NH2)q, —CR4═O or poly alkyloxy that may have been terminally acylated or alkylated; p is an integer 0-3, with the provisos a) p depends on X being halogen, O, S or N, and b) that if several groups R2 are present they may be identical or different; R3 is alkyl, —O-alkyl, hydroxyalkyl, phenylalkyl, with up to 18 carbon atoms in the alkyl part, and R4 is C1-18 alkyl. q is an integer>O representing that one or more hydrogens in R3 may have been replaced with —NH2 or —NH—CR4═O. The polymer article may be used as a chromatography separation medium or in solide phase oligonucleotide synthesis.

    Abstract translation: 具有结构（I）的聚合物制品，其中P包含碱性聚合物和基团-L-CH（-X（R 1）p）-CH 2（-Y（R 2）p）; L是用于引入-X（R1）p和-Y（R2）p的待决基团的一部分; X和Y是卤素，N，S和O; 当X为N，O或S时，R1为氢，烷基，酰基或R2; R2是氢，烷基，烷基芳基或芳烷基，其中烷基部分可以含有1-18个碳，或-R3（-NH-CR4 = O）q或-R3（-NH2）q，-CR4 = O或聚烷氧基，其中 可能已被终止酰化或烷基化; p是0-3的整数，条件是a）p取决于X是卤素，O，S或N，和b）如果存在几个基团R2，它们可以相同或不同; R3是烷基，烷基，-O-烷基，羟基烷基，苯基烷基，在烷基部分具有至多18个碳原子，R4是C1-18烷基。 q是整数> O，表示R3中的一个或多个氢可以被-NH 2或-NH-CR 4 = O代替。 聚合物制品可用作色谱分离介质或溶剂相寡核苷酸合成。

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