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30 条记录 (耗时 0.079 秒)

    Antibodies to HT5GJ57
    1.
    发明授权
    Antibodies to HT5GJ57 失效
    抗体HT5GJ57

    公开(公告)号：US07932361B2

    公开(公告)日：2011-04-26

    申请号：US12268263

    申请日：2008-11-10

    申请人： Steven M. Ruben ,  Craig A. Rosen ,  Gregory A. Endress

    发明人： Steven M. Ruben ,  Craig A. Rosen ,  Gregory A. Endress

    IPC分类号： C07K16/00

    CPC分类号： C07K14/47 ,  A61K38/00 ,  C07K2319/30

    摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

    摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。

    HEMCM42 antibodies
    2.
    发明授权
    HEMCM42 antibodies 有权
    HEMCM42抗体

    公开(公告)号：US07914789B2

    公开(公告)日：2011-03-29

    申请号：US11801040

    申请日：2007-05-07

    申请人： Steven M. Ruben ,  Craig A. Rosen ,  Gregory A. Endress

    发明人： Steven M. Ruben ,  Craig A. Rosen ,  Gregory A. Endress

    IPC分类号： A61K39/395

    CPC分类号： C07K14/47 ,  A61K38/00 ,  C07K16/00

    摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

    摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。

    Antibodies to human growth factor huXAG-3 and methods of use
    3.
    发明授权
    Antibodies to human growth factor huXAG-3 and methods of use 失效
    人类生长因子huXAG-3的抗体及其使用方法

    公开(公告)号：US07060801B2

    公开(公告)日：2006-06-13

    申请号：US10922101

    申请日：2004-08-20

    申请人： Guo-Liang Yu ,  Patrick J. Dillon ,  Reinhard Ebner ,  Gregory A. Endress

    发明人： Guo-Liang Yu ,  Patrick J. Dillon ,  Reinhard Ebner ,  Gregory A. Endress

    IPC分类号： C07K16/00 ,  G01N33/356 ,  G01N33/53

    CPC分类号： C07K14/475 ,  A61K38/00 ,  C07K2317/92

    摘要： The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1, huXAG-2 and huXAG-3 proteins. huXAG-1, huXAG-2 and huXAG-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of huXAG-1, huXAG-2 or huXAG-3 activity. Also provided are diagnostic and therapeutic uses of huXAG-1. huXAG-2 and huXAG-3.

    摘要翻译： 本发明涉及作为新型人生长因子的huXAG-1，huXAG-2和huXAG-3蛋白。 特别地，提供编码huXAG-1，huXAG-2和huXAG-3蛋白的分离的核酸分子。 还提供huXAG-1，huXAG-2和huXAG-3多肽，载体，宿主细胞和用于制备它们的重组方法。 本发明还涉及用于鉴定huXAG-1，huXAG-2或huXAG-3活性的激动剂和拮抗剂的筛选方法。 还提供了huXAG-1的诊断和治疗用途。 huXAG-2和huXAG-3。

    HEMCM42 nucleic acids
    6.
    发明授权
    HEMCM42 nucleic acids 有权
    HEMCM42核酸

    公开(公告)号：US07906634B2

    公开(公告)日：2011-03-15

    申请号：US12324825

    申请日：2008-11-26

    申请人： Steven M. Ruben ,  Craig A. Rosen ,  Gregory A. Endress

    发明人： Steven M. Ruben ,  Craig A. Rosen ,  Gregory A. Endress

    IPC分类号： C07H21/04

    CPC分类号： C07K14/47 ,  A61K38/00 ,  C07K16/00

    摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

    摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。

    Diagnostic methods involving human growth factor huXAG-1
    8.
    发明授权
    Diagnostic methods involving human growth factor huXAG-1 有权
    涉及人类生长因子huXAG-1的诊断方法

    公开(公告)号：US07611846B2

    公开(公告)日：2009-11-03

    申请号：US11368664

    申请日：2006-03-07

    申请人： Guo-Liang Yu ,  Patrick J. Dillon ,  Reinhard Ebner ,  Gregory A. Endress

    发明人： Guo-Liang Yu ,  Patrick J. Dillon ,  Reinhard Ebner ,  Gregory A. Endress

    IPC分类号： G01N33/53 ,  C07K16/00 ,  A61K38/27

    CPC分类号： C07K14/475 ,  A61K38/00 ,  C07K2317/92

    摘要： The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1, huXAG-2 and huXAG-3 proteins. huXAG-1, huXAG-2 and huXAG-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of huXAG-1, huXAG-2 or huXAG-3 activity. Also provided are diagnostic and therapeutic uses of huXAG-1, huXAG-2 and huXAG-3.

    摘要翻译： 本发明涉及作为新型人生长因子的huXAG-1，huXAG-2和huXAG-3蛋白。 特别地，提供编码huXAG-1，huXAG-2和huXAG-3蛋白的分离的核酸分子。 还提供huXAG-1，huXAG-2和huXAG-3多肽，载体，宿主细胞和用于制备它们的重组方法。 本发明还涉及用于鉴定huXAG-1，huXAG-2或huXAG-3活性的激动剂和拮抗剂的筛选方法。 还提供了huXAG-1，huXAG-2和huXAG-3的诊断和治疗用途。