公开(公告)号：US09822387B2

公开(公告)日：2017-11-21

申请号：US14235756

申请日：2012-07-27

申请人： Ryota Fujii ,  Tomokazu Shirai ,  Tadashi Araki ,  Koh Amano ,  Yoshiko Matsumoto ,  Toshihiro Tateno ,  Nozomi Takebayashi ,  Takashi Morishige ,  Hitoshi Takahashi ,  Mitsufumi Wada ,  Hiroshi Shimizu ,  Chikara Furusawa ,  Takashi Hirasawa ,  Tomonori Hidesaki ,  Ayako Endo ,  Dominik Lukas Jürgen-Lohmann ,  Anjali Madhavan ,  Su Sun Chong

发明人： Ryota Fujii ,  Tomokazu Shirai ,  Tadashi Araki ,  Koh Amano ,  Yoshiko Matsumoto ,  Toshihiro Tateno ,  Nozomi Takebayashi ,  Takashi Morishige ,  Hitoshi Takahashi ,  Mitsufumi Wada ,  Hiroshi Shimizu ,  Chikara Furusawa ,  Takashi Hirasawa ,  Tomonori Hidesaki ,  Ayako Endo ,  Dominik Lukas Jürgen-Lohmann ,  Anjali Madhavan ,  Su Sun Chong

IPC分类号： C12N1/20 ,  C12N15/00 ,  C12N9/00 ,  C12N9/88 ,  C12N9/02 ,  C07H21/04 ,  C12P19/40 ,  C12P13/14 ,  C12N9/04 ,  C12P7/04 ,  C12P7/28 ,  C12P19/32

CPC分类号： C12P19/40 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/88 ,  C12N9/93 ,  C12P7/04 ,  C12P7/28 ,  C12P13/14 ,  C12P19/32 ,  C12Y101/0106 ,  C12Y101/01081 ,  C12Y401/01047 ,  C12Y401/03024 ,  C12Y602/01009

摘要： An acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same are provided. An acetyl-CoA-producing microorganism including an acetyl-CoA production cycle obtained by imparting at least one type of enzymatic activity selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase, and hydroxypyruvate reductase, to a microorganism.

公开(公告)号：US09640144B2

公开(公告)日：2017-05-02

申请号：US14377245

申请日：2012-02-13

申请人： Hiroshi Shimizu ,  Kazuhiko Yoshizawa ,  Motoyuki Suzuki ,  Hideo Nishijima ,  Nobuo Masuoka

发明人： Hiroshi Shimizu ,  Kazuhiko Yoshizawa ,  Motoyuki Suzuki ,  Hideo Nishijima ,  Nobuo Masuoka

IPC分类号： G06F3/14 ,  G09G5/12 ,  G06F3/0488 ,  G06K9/22 ,  H04M3/56 ,  H04N9/31 ,  G06F3/041 ,  G06Q10/10 ,  H04N7/15

CPC分类号： G09G5/12 ,  G06F3/0416 ,  G06F3/04883 ,  G06F3/1423 ,  G06F3/1454 ,  G06K9/222 ,  G06Q10/101 ,  G09G2354/00 ,  G09G2360/04 ,  G09G2370/16 ,  H04M3/567 ,  H04N7/15 ,  H04N9/3179

摘要： Blocking a view of a whiteboard by a position of an attendee writing thereon is prevented, and writing records made by all attendees are stored to use the writing records including a course of the written records later. Each terminal of the attendees has a touch-panel-equipped terminal can divide any input line drawing on the terminal into line segment data, successively transmit the line segment data to the controller, and display line drawing information on the display of the touch-panel-equipped terminal. A liquid crystal projector having a controller that can be embedded therein or connected thereto is provided, the controller can sequentially record line drawing information transmitted from each touch-panel-equipped terminal in a data base, add the line drawing information to a video image memory of the whiteboard, and project the video image memory contents onto a wall surface while transmitting information of the data base to each touch-panel-equipped terminal.

公开(公告)号：US09548140B2

公开(公告)日：2017-01-17

申请号：US13992999

申请日：2011-12-06

申请人： Hiroshi Shimizu ,  Ryo Fujimoto ,  Kentaro Mori ,  Hiromu Okamoto ,  Hisashi Sekimoto ,  Hiroyuki Iseki

发明人： Hiroshi Shimizu ,  Ryo Fujimoto ,  Kentaro Mori ,  Hiromu Okamoto ,  Hisashi Sekimoto ,  Hiroyuki Iseki

IPC分类号： G21C13/00 ,  G21C13/024 ,  F22B37/24 ,  E04B1/16

CPC分类号： G21C13/024 ,  E04B1/16 ,  F22B37/248 ,  Y02E30/40

摘要： A nuclear reactor vessel structure includes an inner peripheral tube-shaped steel plate, an outer peripheral tube-shaped steel plate, and an intermediate tube-shaped steel plate disposed between the inner and outer peripheral tube-shaped steel plates, and is configured to support a nuclear reactor vessel on the inner peripheral side of a tube-shaped structure with concrete placed between the steel plates. The nuclear reactor vessel structure includes a support having a tube-shaped plate disposed on the inner peripheral side of the intermediate tube-shaped steel plate, and an annular plate which protrudes to the inner peripheral side of the tube-shaped plate and to which a connection section is affixed. The support is affixed to the concrete, which is placed between the inner peripheral and the intermediate tube-shaped steel plates, by first bar members, and the support is also affixed to the inner peripheral tube-shaped steel plate by second bar members.

摘要翻译： 核反应堆容器结构包括内周管状钢板，外周管状钢板和设置在内外管状钢板之间的中间管状钢板，构成为支承 在管状结构的内周侧具有放置在钢板之间的混凝土的核反应堆容器。 核反应堆容器结构包括具有设置在中间管状钢板的内周侧的管状板的支撑体和向管状板的内周侧突出的环状板， 连接部分被贴上。 支撑体通过第一杆构件固定在内周和中间管状钢板之间的混凝土上，并且支撑体也通过第二杆构件固定到内周管状钢板。

公开(公告)号：US09051333B2

公开(公告)日：2015-06-09

申请号：US14111262

申请日：2012-04-13

申请人： Yoshikazu Kawano ,  Yoshikazu Haraguchi ,  Hirofumi Sasaki ,  Yukitaka Uematsu ,  Hidetsugu Tsubouchi ,  Hiromi Yata ,  Hiroshi Shimizu ,  Kazuho Kohashi ,  Motohiro Itotani ,  Kuninori Tai ,  Isao Takemura ,  Mikayo Hayashi ,  Hiroyuki Hashizume ,  Miki Matsuba ,  Izuru Nakamura ,  Xiuhao Chen ,  Makoto Matsumoto

发明人： Yoshikazu Kawano ,  Yoshikazu Haraguchi ,  Hirofumi Sasaki ,  Yukitaka Uematsu ,  Hidetsugu Tsubouchi ,  Hiromi Yata ,  Hiroshi Shimizu ,  Kazuho Kohashi ,  Motohiro Itotani ,  Kuninori Tai ,  Isao Takemura ,  Mikayo Hayashi ,  Hiroyuki Hashizume ,  Miki Matsuba ,  Izuru Nakamura ,  Xiuhao Chen ,  Makoto Matsumoto

IPC分类号： C07D498/04 ,  A61K31/5383

CPC分类号： C07D498/04

摘要： The present invention provides a novel 6,7-dihydroimidazo[2,1-b][1,3]oxazine compound that has excellent bactericidal action against tubercle bacilli, multidrug-resistant tubercle bacilli, and atypical acid-fast bacilli. Specifically, the present invention provides a compound represented by Formula (1): or a salt thereof, wherein R1 represents tetrahydroisoquinolyl, tetrahydroquinolyl, tetrahydrobenzoazepinyl, benzoxazolyl, benzothiazolyl, indolyl, isoindolinyl, naphthyl, quinolyl, phenyl, biphenylyl, or pyridyl, these groups being optionally substituted, the phenyl, biphenylyl, and pyridyl represented by R1 each being substituted directly or via a linker with at least one group selected from the group consisting of tetrahydropyridyl, diazepanyl, diazabicycloheptanyl, tetrahydrotriazolopyrazinyl, tetrahydroimidazopyrazinyl, azabicyclooctanyl, oxazolyl, piperazinyl, piperidyl, thiazolyl, and the like, each of these groups being optionally substituted; and R2 represents hydrogen or lower alkyl. The present invention further provides a pharmaceutical composition containing the above.

摘要翻译： 本发明提供了对结核杆菌，多重耐药性结核杆菌和非典型抗酸杆菌具有优异的杀菌作用的新型6,7-二氢咪唑并[2,1-b] [1,3]恶嗪化合物。 具体地说，本发明提供由式（1）表示的化合物或其盐，其中R1表示四氢异喹啉基，四氢喹啉基，四氢苯并氮杂基，苯并恶唑基，苯并噻唑基，吲哚基，异吲哚啉基，萘基，喹啉基，苯基，联苯基或吡啶基。 任选被取代的苯基，联苯基和吡啶基，其各自被直接取代或经由具有至少一个选自四氢吡啶基，二氮杂环庚烷基，二氮杂双环庚烷基，四氢三唑并吡嗪基，四氢咪唑并吡嗪基，氮杂双环辛基，恶唑基，哌嗪基，哌啶基 ，噻唑基等，这些基团各自任选被取代; 并且R 2表示氢或低级烷基。 本发明还提供含有上述物质的药物组合物。

公开(公告)号：US08744170B2

公开(公告)日：2014-06-03

申请号：US13563908

申请日：2012-08-01

申请人： Hiroyuki Kato ,  Jun Muraki ,  Hiroshi Shimizu ,  Hiroyuki Hoshino ,  Erina Ichikawa

发明人： Hiroyuki Kato ,  Jun Muraki ,  Hiroshi Shimizu ,  Hiroyuki Hoshino ,  Erina Ichikawa

IPC分类号： G06K9/00 ,  G06K9/40 ,  H04N5/235

CPC分类号： G06T7/75 ,  G06T2207/10152

摘要： An image processing apparatus includes an obtaining section, a detection section, a first identification section and a second identification section. The obtaining section obtains image data of a first picked-up image and a second picked-up image picked up by an image pickup section. The detection section detects a brightness change region where brightness changes at predetermined time intervals in the first picked-up image on the basis of the obtained image data of the first picked-up image. The first identification section performs straight line detection processing on the obtained image data of the second picked-up image to detect a straight line, so as to identify a candidate straight line in a corresponding region corresponding to the brightness change region. The second identification section identifies a quadrilateral region including the candidate straight line as an extraction candidate region in the second picked-up image.

摘要翻译： 图像处理装置包括获取部，检测部，第一识别部和第二识别部。 获取部分获取由图像拾取部拾取的第一拍摄图像和第二拍摄图像的图像数据。 检测部根据所获得的第一拍摄图像的图像数据，检测第一拍摄图像中的亮度以规定的时间间隔变化的亮度变化区域。 第一识别部分对获得的第二拍摄图像的图像数据进行直线检测处理以检测直线，以便识别与亮度变化区域对应的对应区域中的候选直线。 第二识别部分识别包括候选直线的四边形区域作为第二拍摄图像中的提取候选区域。

公开(公告)号：US08731129B2

公开(公告)日：2014-05-20

申请号：US10569226

申请日：2005-08-10

申请人： Hiroki Tamaki ,  Yuichi Saito ,  Kiminobu Hojo ,  Tadashi Kimura ,  Hiroshi Shimizu ,  Akio Kitada

发明人： Hiroki Tamaki ,  Yuichi Saito ,  Kiminobu Hojo ,  Tadashi Kimura ,  Hiroshi Shimizu ,  Akio Kitada

IPC分类号： G21C19/00

CPC分类号： G21F5/08 ,  G21Y2002/201 ,  G21Y2002/304 ,  G21Y2004/303

摘要： A first shock absorber group is obtained by combining a plurality of shock absorber blocks, absorbs a shock in a direction parallel to an end surface of a cask, consisting of a first material. A second shock absorber group absorbs the shock in a direction perpendicular to or oblique with respect to the end surface, consisting of a second material having a weaker compressive strength than the first material. A third shock absorber group absorbs the shock in a direction perpendicular to the end surface, consisting of a third material having a weaker compressive strength than the second material. A space is provided at least in the first shock absorber group.

摘要翻译： 通过组合多个减震器块，在由第一材料构成的平行于桶的端面的方向吸收冲击来获得第一减震器组。 第二减震器组在垂直于或相对于端面倾斜的方向上吸收冲击，由具有比第一材料更弱的抗压强度的第二材料组成。 第三减震器组件在垂直于端面的方向上吸收冲击，由具有比第二材料更弱的抗压强度的第三材料组成。 至少在第一减震器组中设置空间。

公开(公告)号：US08705948B2

公开(公告)日：2014-04-22

申请号：US13602448

申请日：2012-09-04

申请人： Hiroyuki Hoshino ,  Jun Muraki ,  Hiroshi Shimizu ,  Erina Ichikawa ,  Hiroyuki Kato

发明人： Hiroyuki Hoshino ,  Jun Muraki ,  Hiroshi Shimizu ,  Erina Ichikawa ,  Hiroyuki Kato

IPC分类号： H04N5/783 ,  H04N21/234

CPC分类号： H04N21/23418 ,  G11B27/005 ,  G11B27/105 ,  G11B27/28 ,  H04N5/783

摘要： A video playback device including a playback section which replays a video, a setting section which sets a predetermined area within the video frames being replayed by the playback section, a detecting section which detects whether or not a predetermined subject is included within the predetermined area, a selecting section which selectively switches between a first playback speed and a second playback speed based on the timing of the detection by the detecting section, and a control section which controls the playback speed of the playback section in accordance with a result of the selection by the selecting section.

摘要翻译： 一种视频播放装置，包括重放视频的重放部分，设置部分，其设置由播放部分重播的视频帧内的预定区域;检测部分，其检测预定对象是否包含在预定区域内; 选择部分，其基于检测部分的检测的定时选择性地在第一播放速度和第二播放速度之间切换;以及控制部分，其根据所选择的结果控制播放部分的播放速度， 选择部分。

公开(公告)号：US20140031342A1

公开(公告)日：2014-01-30

申请号：US14111262

申请日：2012-04-13

申请人： Yoshikazu Kawano ,  Yoshikazu Haraguchi ,  Hirofumi Sasaki ,  Yukitaka Uematsu ,  Hidetsugu Tsubouchi ,  Hiromi Yata ,  Hiroshi Shimizu ,  Kazuho Kohashi ,  Motohiro Itotani ,  Kuninori Tai ,  Isao Takemura ,  Mikayo Hayashi ,  Hiroyuki Hashizume ,  Miki Matsuba ,  Izuru Nakamura ,  Xiuhao Chen ,  Makoto Matsumoto

发明人： Yoshikazu Kawano ,  Yoshikazu Haraguchi ,  Hirofumi Sasaki ,  Yukitaka Uematsu ,  Hidetsugu Tsubouchi ,  Hiromi Yata ,  Hiroshi Shimizu ,  Kazuho Kohashi ,  Motohiro Itotani ,  Kuninori Tai ,  Isao Takemura ,  Mikayo Hayashi ,  Hiroyuki Hashizume ,  Miki Matsuba ,  Izuru Nakamura ,  Xiuhao Chen ,  Makoto Matsumoto

IPC分类号： C07D498/04

CPC分类号： C07D498/04

摘要： The present invention provides a novel 6,7-dihydroimidazo[2,1-b][1,3]oxazine compound that has excellent bactericidal action against tubercle bacilli, multidrug-resistant tubercle bacilli, and atypical acid-fast bacilli. Specifically, the present invention provides a compound represented by Formula (1): or a salt thereof, wherein R1 represents tetrahydroisoquinolyl, tetrahydroquinolyl, tetrahydrobenzoazepinyl, benzoxazolyl, benzothiazolyl, indolyl, isoindolinyl, naphthyl, quinolyl, phenyl, biphenylyl, or pyridyl, these groups being optionally substituted, the phenyl, biphenylyl, and pyridyl represented by R1 each being substituted directly or via a linker with at least one group selected from the group consisting of tetrahydropyridyl, diazepanyl, diazabicycloheptanyl, tetrahydrotriazolopyrazinyl, tetrahydroimidazopyrazinyl, azabicyclooctanyl, oxazolyl, piperazinyl, piperidyl, thiazolyl, and the like, each of these groups being optionally substituted; and R2 represents hydrogen or lower alkyl. The present invention further provides a pharmaceutical composition containing the above.

摘要翻译： 本发明提供了对结核杆菌，多重耐药性结核杆菌和非典型抗酸杆菌具有优异的杀菌作用的新型6,7-二氢咪唑并[2,1-b] [1,3]恶嗪化合物。 具体地说，本发明提供由式（1）表示的化合物或其盐，其中R1表示四氢异喹啉基，四氢喹啉基，四氢苯并氮杂基，苯并恶唑基，苯并噻唑基，吲哚基，异吲哚啉基，萘基，喹啉基，苯基，联苯基或吡啶基。 任选被取代的苯基，联苯基和吡啶基，其各自被直接取代或经由具有至少一个选自四氢吡啶基，二氮杂环庚烷基，二氮杂双环庚烷基，四氢三唑并吡嗪基，四氢咪唑并吡嗪基，氮杂双环辛基，恶唑基，哌嗪基，哌啶基 ，噻唑基等，这些基团各自任选被取代; 并且R 2表示氢或低级烷基。 本发明还提供含有上述物质的药物组合物。

公开(公告)号：US08569991B2

公开(公告)日：2013-10-29

申请号：US12928271

申请日：2010-12-07

申请人： Saburo Manaka ,  Akira Takakura ,  Kenji Ogasawara ,  Kazumi Sakumoto ,  Shotaro Kamiyama ,  Keishi Honmura ,  Kosuke Yamamoto ,  Hiroshi Shimizu

发明人： Saburo Manaka ,  Akira Takakura ,  Kenji Ogasawara ,  Kazumi Sakumoto ,  Shotaro Kamiyama ,  Keishi Honmura ,  Kosuke Yamamoto ,  Hiroshi Shimizu

IPC分类号： H02P8/00

CPC分类号： G04C3/143

摘要： A stepping motor control circuit includes a rotation detection circuit that detects an induced signal and detects whether or not the induced signal exceeds a predetermined reference threshold voltage in a detection segment having a plurality of detection areas, and a control unit that determines the state of rotation of a stepping motor on the basis of a pattern indicating whether or not the induced signals exceed the reference threshold voltage and, on the basis of the result of detection, controls the driving of the stepping motor with anyone of a plurality of main drive pulses different from each other in energy or a correction drive pulse having larger energy than the main drive pulse. An ineffective area is provided between at least the two detection areas, and the control unit determines the state of rotation of the stepping motor without considering the induced signal.

摘要翻译： 步进电动机控制电路包括检测感应信号并检测在具有多个检测区域的检测段中感应信号是否超过预定参考阈值电压的旋转检测电路，以及确定旋转状态的控制单元 基于指示感应信号是否超过参考阈值电压的模式，并且基于检测结果，控制具有多个主驱动脉冲中的任何一个的步进电机的驱动 能量相差或具有比主驱动脉冲大的能量的校正驱动脉冲。 在至少两个检测区域之间提供无效区域，并且控制单元在不考虑感应信号的情况下确定步进电机的旋转状态。

公开(公告)号：US20130211170A1

公开(公告)日：2013-08-15

申请号：US13816077

申请日：2011-08-11

申请人： Koh Amano ,  Tomokazu Shirai ,  Hitoshi Takahashi ,  Junichiro Hirano ,  Yoshiko Matsumoto ,  Nozomi Takebayashi ,  Mitsufumi Wada ,  Hiroshi Shimizu ,  Chikara Furusawa ,  Takashi Hirasawa

发明人： Koh Amano ,  Tomokazu Shirai ,  Hitoshi Takahashi ,  Junichiro Hirano ,  Yoshiko Matsumoto ,  Nozomi Takebayashi ,  Mitsufumi Wada ,  Hiroshi Shimizu ,  Chikara Furusawa ,  Takashi Hirasawa

IPC分类号： C12P7/04 ,  C12P7/28 ,  C12N15/70

CPC分类号： C12P7/04 ,  C07C1/24 ,  C07C45/002 ,  C07C2529/70 ,  C07K14/245 ,  C12N9/0006 ,  C12N9/88 ,  C12N15/70 ,  C12P7/28 ,  Y02P20/52 ,  C07C11/06 ,  C07C49/08

摘要： An isopropyl alcohol-producing Escherichia coli includes an isopropyl alcohol production system, wherein an activity of transcriptional repressor GntR is inactivated, and the isopropyl alcohol-producing Escherichia coli preferably further includes a group of auxiliary enzymes having an enzyme activity expression pattern with which isopropyl alcohol production capacity achieved by the inactivation of the GntR activity is maintained or enhanced. A method of producing isopropyl alcohol includes producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli. A method of producing acetone includes contacting the isopropyl alcohol obtained by the isopropyl alcohol production method with a complex oxide that includes zinc oxide and at least one oxide containing a Group 4 element, and that is prepared by coprecipitation. A method of producing propylene includes contacting isopropyl alcohol and acetone obtained by the production method with a solid acidic substance and a Cu-containing hydrogenation catalyst as catalysts.

摘要翻译： 产生异丙醇的大肠杆菌包括异丙醇生产系统，其中转录阻遏物GntR的活性被灭活，产生异丙醇的大肠杆菌优选还包括具有酶活性表达模式的一组辅酶，其中异丙醇 保持或增强GntR活性失活所产生的生产能力。 制造异丙醇的方法包括使用产生异丙醇的大肠杆菌从植物来源的原料生产异丙醇。 制造丙酮的方法包括使异丙醇制造方法得到的异丙醇与包含氧化锌和至少一种含有4族元素的氧化物复合氧化物接触，并通过共沉淀制备。 制备丙烯的方法包括使通过制备方法获得的异丙醇和丙酮与固体酸性物质和含Cu氢化催化剂作为催化剂接触。