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    Method for diagnosing esophageal cancer
    2.
    发明授权
    Method for diagnosing esophageal cancer 有权
    诊断食管癌的方法

    公开(公告)号：US08945849B2

    公开(公告)日：2015-02-03

    申请号：US12993792

    申请日：2009-05-21

    Applicant: Akira Myomoto ,  Satoko Kozono ,  Hideo Akiyama ,  Hitoshi Nobumasa ,  Yutaka Shimada ,  Gozoh Tsujimoto

    Inventor： Akira Myomoto ,  Satoko Kozono ,  Hideo Akiyama ,  Hitoshi Nobumasa ,  Yutaka Shimada ,  Gozoh Tsujimoto

    IPC: C12Q1/68 ,  G01N33/574

    CPC classification number: C12Q1/6886 ,  C12Q2600/158 ,  G01N33/57446

    Abstract: This invention relates to a composition, kit, or DNA chip for use in diagnosis of esophageal cancer, which comprises a plurality of polynucleotides selected from the group consisting of polynucleotides whose expression levels are varied in esophageal cancer tissues obtained from esophageal cancer patients when compared with cancer-free esophageal tissues obtained from esophageal cancer patients, mutants thereof, and fragments thereof, and to a method for detecting esophageal cancer using the composition, kit, or DNA chip.

    Abstract translation: 本发明涉及用于食管癌诊断的组合物，试剂盒或DNA芯片，其包含多个选自下组的多核苷酸，所述多核苷酸选自食管癌患者食管癌组织中表达水平变化的多核苷酸，与 从食管癌患者获得的无癌食管组织，其突变体及其片段，以及使用该组合物，试剂盒或DNA芯片检测食管癌的方法。

    SOLUTION FOR EXTRACTION OF RNA
    3.
    发明申请
    SOLUTION FOR EXTRACTION OF RNA 审中-公开
    提取RNA的解决方案

    公开(公告)号：US20130144049A1

    公开(公告)日：2013-06-06

    申请号：US13816792

    申请日：2011-08-17

    Applicant: Makiko Yoshimoto ,  Hideo Akiyama ,  Hitoshi Nobumasa

    Inventor： Makiko Yoshimoto ,  Hideo Akiyama ,  Hitoshi Nobumasa

    IPC: C12N15/10

    CPC classification number: C12N15/1003 ,  G01N1/286 ,  G01N2001/2866

    Abstract: A solution for extracting substantially pure RNA from a biological sample is disclosed. The solution for extracting RNA from a biological sample containing RNA and at least DNA comprises: (a) phenol in an amount of more than 50% by volume based on the total amount of the solution; (b) a polyol in an amount of 3 to 10% by volume based on the total amount of the solution; (c) a guanidinium salt at a concentration of 0.5 to 2.0 M based on the total amount of the solution; (d) a thiocyanate at a concentration of 0.1 to 0.5 M based on the total amount of the solution; and (e) a buffer for maintaining the pH of the solution at 4 to 6.

    Abstract translation: 公开了从生物样品中提取基本上纯的RNA的溶液。 用于从含有RNA和至少DNA的生物样品中提取RNA的解决方案包括：（a）基于溶液总量大于50体积％的苯酚; （b）相对于溶液的总量为3〜10体积％的多元醇; （c）基于溶液的总量，浓度为0.5至2.0M的胍盐; （d）基于溶液的总量，浓度为0.1至0.5M的硫氰酸盐; 和（e）用于将溶液的pH保持在4-6的缓冲液。

    SUBSTRATE FOR LAB-ON-A-CHIP
    6.
    发明申请
    SUBSTRATE FOR LAB-ON-A-CHIP 审中-公开
    基于实验室的芯片

    公开(公告)号：US20090297733A1

    公开(公告)日：2009-12-03

    申请号：US12540832

    申请日：2009-08-13

    Applicant: Yoshiaki Yamazaki ,  Naoki Kawazoe ,  Masashi Higasa ,  Giman Jung ,  Hitoshi Nobumasa ,  Yuji Murakami

    Inventor： Yoshiaki Yamazaki ,  Naoki Kawazoe ,  Masashi Higasa ,  Giman Jung ,  Hitoshi Nobumasa ,  Yuji Murakami

    IPC: C23C14/28

    CPC classification number: G01N27/44747

    Abstract: A lab-on-chip substrate includes a resin having a silicon content of 10% or less by weight as its base material and a hydrophilic polymer covalently bound onto the surface thereof by high-energy ray irradiation suitable for a protein-processing chip. The lab-on-chip substrate is resistant to washing and usable for an extended period of time without adsorption of proteins on the base material surface, i.e., a protein electrophoretic polymeric chip having a microchannel allowing high-accuracy analysis of trace amounts of proteins because of reduction in the amount of detection noise.

    Abstract translation: 片上芯片基板包括硅含量为10重量％以下的树脂作为其基材，以及通过适用于蛋白质加工芯片的高能射线照射共价结合到其表面上的亲水性聚合物。 芯片上的实验室衬底耐洗涤并且可在不在基材表面上吸附蛋白质的情况下使用，即具有微通道的蛋白质电泳聚合物芯片，允许对微量蛋白进行高精度分析，因为 检测噪声量减少。

    Dielectric paste and manufacturing method of plasma display
    8.
    发明申请
    Dielectric paste and manufacturing method of plasma display 失效

    公开(公告)号：US20060189745A1

    公开(公告)日：2006-08-24

    申请号：US11408186

    申请日：2006-04-21

    Applicant: Hiroko Mitsui ,  Junji Mata ,  Kentaro Okuyama ,  Akihiko Tanaka ,  Hitoshi Nobumasa

    Inventor： Hiroko Mitsui ,  Junji Mata ,  Kentaro Okuyama ,  Akihiko Tanaka ,  Hitoshi Nobumasa

    IPC: C08K3/40

    CPC classification number: H01J9/242 ,  C03C8/04 ,  C03C8/16 ,  C03C17/008 ,  C03C17/04 ,  H01J2211/36 ,  H01J2211/38

    Abstract: A dielectric paste of the present invention contains a binder resin, a cross-linking agent, a thermal polymerization initiator, and an inorganic powder, wherein the content of the thermal polymerization initiator is 3 to 30 parts by weight to 100 parts by weight of the total of the binder resin and the cross-linking agent. A method of manufacturing a plasma display, of the present invention, includes a first step of forming electrode patterns using an electrode paste, a second step of forming a dielectric paste coating film using a dielectric paste, a third step of forming barrier rib patterns using a barrier rib paste, a subsequent step of simultaneously firing at least the electrode patterns, the dielectric paste coating film, and the barrier rib patterns, and a step of performing curing after the second step. The present invention provides a method of manufacturing a plasma display, in which the electrode patterns, the dielectric paste coating film, and the barrier rib patterns can be simultaneously fired without any defects such as disconnections or cracks.

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