摘要:
A process for preparing a 1-substituted 5-hydroxymethylimidazole of the formula: , wherein R represents alkyl, hydroxyalkyl, allyl, or substituted or unsubstituted arylmethyl or diarylmethyl, comprising the step of reacting a 1-substituted 2-mercapto-5-hydroxymethylimidazole of the formula: , wherein R is as defined above, in the presence of a transition metal catalyst and an oxidizing agent in a solvent.
摘要:
A vacuum apparatus having a suction nozzle, an air suction unit to which the suction nozzle is pivotally connected and which fluidly communicates with the suction nozzle through a connection channel, a dirt receptacle which has at least two collecting parts fluidly communicating with at least two outlets formed at the air suction unit, respectively.
摘要:
The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, n1 and Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.
摘要:
A vacuum apparatus having a suction nozzle, an air suction unit to which the suction nozzle is pivotally connected and which fluidly communicates with the suction nozzle through a connection channel, a dirt receptacle which has at least two collecting parts fluidly communicating with at least two outlets formed at the air suction unit, respectively.
摘要:
The present invention relates to novel hydantoin compounds represented by formula (I) which shows an inhibitory activity against farnesyl transferase, and thus can be used as an anti-cancer agent, or pharmaceutically acceptable salts thereof, in which R1, R2, R3 and R4 are as defined in the present application. The present invention also relates to a process for preparation of the compound of formula (I), and to an anti-cancer composition comprising the compound of formula (I) as an active ingredient.