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    NOVEL TRISCATIONIC AMPHIPHILE DERIVATIVE COMPOUNDS HAVING A PENDENT ALCOHOL GROUP, COMPOSITIONS THEREOF, AND METHODS FOR MAKING SAME
    2.
    发明申请
    NOVEL TRISCATIONIC AMPHIPHILE DERIVATIVE COMPOUNDS HAVING A PENDENT ALCOHOL GROUP, COMPOSITIONS THEREOF, AND METHODS FOR MAKING SAME 有权
    具有相关酒精组合物的新型三元衍生化合物及其组合物及其制备方法

    公开(公告)号：US20170029363A1

    公开(公告)日：2017-02-02

    申请号：US15225522

    申请日：2016-08-01

    申请人： James Madison Innovations, Inc.

    发明人： Kevin L. Caran ,  Kyle Seifert

    IPC分类号： C07C215/14 ,  A01N33/12

    CPC分类号： A01N33/12 ,  C07C215/40

    摘要： The inventive subject matter relates to compounds of Formula I, compositions thereof, and processes for making such compounds as further described herein. The inventive compounds and compositions have antimicrobial properties and are useful as environmental disinfectants, topical cleansers such as topical personal care compositions, sanitizers, preservatives, in water treatment, as permanent or erodible coatings for medical devices and appliances, and in therapeutics. Additionally, the compounds of Formula I will serve as synthetic intermediates for making additional novel derivatives of triscationic amphiphile compounds.

    摘要翻译： 本发明主题涉及式I化合物，其组合物，以及制备本文进一步描述的化合物的方法。 本发明的化合物和组合物具有抗微生物性质，并且可用作环境消毒剂，局部清洁剂如局部个人护理组合物，消毒剂，防腐剂，在水处理中，作为用于医疗设备和器具的永久或可蚀刻涂层以及治疗剂。 此外，式I的化合物将用作制备三阳离子两亲物化合物的其它新衍生物的合成中间体。

    Systems, methods and apparatus for monitoring conditions of physical or virtual objects
    6.
    发明授权
    Systems, methods and apparatus for monitoring conditions of physical or virtual objects 有权

    公开(公告)号：US11448544B2

    公开(公告)日：2022-09-20

    申请号：US16904304

    申请日：2020-06-17

    申请人： James Madison Innovations, Inc.

    发明人： Emil Habib Salib

    IPC分类号： G01F23/68 ,  G01F23/22 ,  G01F15/06 ,  G01F15/063

    摘要： A system, method and apparatus for providing real-time alerts regarding the status of agricultural infrastructure resources, which may be stationary and/or mobile, such as water level, water temperature, trough, water pump, drone, and livestock that are equipped with sensors. The system adaptively aggregates and processes the sensed data from multiple resources and animals using low cost readily available wireless local network and sends an alert cost effectively using various messaging methods, such as SMS, MMS, PSTN, VoIP, HTTP, and HTTPS, over various wireless communications networks, such as cellular, satellite, or UHF, depending on availability, cost and quality of service.

    Triscationic amphiphile derivative compounds having a pendent alcohol group, compositions thereof, and methods for making same
    7.
    发明授权
    Triscationic amphiphile derivative compounds having a pendent alcohol group, compositions thereof, and methods for making same 有权
    具有侧链醇基的三阳离子两亲性衍生物化合物及其组合物及其制备方法

    公开(公告)号：US09556109B1

    公开(公告)日：2017-01-31

    申请号：US15225522

    申请日：2016-08-01

    申请人： James Madison Innovations, Inc.

    发明人： Kevin L. Caran ,  Kyle Seifert

    IPC分类号： C07C215/14 ,  A01N33/12

    CPC分类号： A01N33/12 ,  C07C215/40

    摘要： The inventive subject matter relates to compounds of Formula I, compositions thereof, and processes for making such compounds as further described herein. The inventive compounds and compositions have antimicrobial properties and are useful as environmental disinfectants, topical cleansers such as topical personal care compositions, sanitizers, preservatives, in water treatment, as permanent or erodible coatings for medical devices and appliances, and in therapeutics. Additionally, the compounds of Formula I will serve as synthetic intermediates for making additional novel derivatives of triscationic amphiphile compounds.

    摘要翻译： 本发明主题涉及式I化合物，其组合物，以及制备本文进一步描述的化合物的方法。 本发明的化合物和组合物具有抗微生物性质，并且可用作环境消毒剂，局部清洁剂如局部个人护理组合物，消毒剂，防腐剂，在水处理中，作为用于医疗设备和器具的永久或可蚀刻涂层以及治疗剂。 此外，式I的化合物将用作制备三阳离子两亲物化合物的其它新衍生物的合成中间体。

    Vibratory Cough Suppression
    8.
    发明申请
    Vibratory Cough Suppression 有权

    公开(公告)号：US20210393477A1

    公开(公告)日：2021-12-23

    申请号：US17464406

    申请日：2021-09-01

    申请人： James Madison Innovations, Inc.

    发明人： Christy Leslie Ludlow

    IPC分类号： A61H23/00 ,  A61H23/02 ,  G09B19/04 ,  H04W4/80

    摘要： An apparatus comprises a vibrational transducer, a placement band, a driver module and a control module. The placement band is configured to hold the vibrational transducer adjacent to the skin surface overlying the cricoid cartilage and trachea region of a patient's neck. The driver module is configured to apply a drive signal to the vibrational transducer. The control module is configured to receive at least one input configured to provide vibrational operating information and control the driver module to cause the vibrational transducer to apply a vibratory stimulation in an amount determined, at least in part, by the vibrational operating information.

    Vibratory Cough Suppression
    9.
    发明申请
    Vibratory Cough Suppression 审中-公开
    振动咳嗽抑制

    公开(公告)号：US20170007497A1

    公开(公告)日：2017-01-12

    申请号：US15204825

    申请日：2016-07-07

    申请人： James Madison Innovations, Inc.

    发明人： Christy Leslie Ludlow

    IPC分类号： A61H23/00 ,  A61H23/02

    CPC分类号： A61H23/008 ,  A61H23/02 ,  A61H23/0236 ,  A61H23/0245 ,  A61H23/0254 ,  A61H2201/5012 ,  A61H2201/5015 ,  A61H2201/5058 ,  A61H2201/5071 ,  A61H2201/5076 ,  A61H2205/04 ,  A61H2230/405 ,  G09B19/04 ,  H04W4/80

    摘要： An apparatus comprises a vibrational transducer, a placement band, a driver module and a control module. The placement band is configured to hold the vibrational transducer adjacent to the skin surface overlying the cricoid cartilage and trachea region of a patient's neck. The driver module is configured to apply a drive signal to the vibrational transducer. The control module is configured to receive at least one input configured to provide vibrational operating information and control the driver module to cause the vibrational transducer to apply a vibratory stimulation in an amount determined, at least in part, by the vibrational operating information.

    摘要翻译： 一种装置包括振动传感器，放置带，驱动器模块和控制模块。 放置带配置成将振动传感器保持在邻近皮肤表面，覆盖患者颈部的环状软骨和气管区域。 驱动器模块被配置为向振动换能器施加驱动信号。 所述控制模块被配置为接收被配置为提供振动操作信息的至少一个输入，并且控制所述驱动器模块以使所述振动传感器以至少部分地由所述振动操作信息确定的量施加振动刺激。