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15 条记录 (耗时 0.012 秒)

    PENDANT HYDROPHILE BEARING BIODEGRAADABLE COMPOSITIONS AND RELATED DEVICES
    1.
    发明申请
    PENDANT HYDROPHILE BEARING BIODEGRAADABLE COMPOSITIONS AND RELATED DEVICES 有权
    供应商水泥轴承生物可降解组合物及相关设备

    公开(公告)号：US20140037711A1

    公开(公告)日：2014-02-06

    申请号：US13880666

    申请日：2011-10-20

    申请人： James Parakka ,  Ananth Iyer

    发明人： James Parakka ,  Ananth Iyer

    IPC分类号： A61L31/06 ,  A61L31/16

    CPC分类号： A61L31/06 ,  A61L15/22 ,  A61L15/24 ,  A61L15/26 ,  A61L15/28 ,  A61L15/44 ,  A61L15/50 ,  A61L15/58 ,  A61L15/64 ,  A61L26/009 ,  A61L31/041 ,  A61L31/048 ,  A61L31/148 ,  A61L31/16 ,  C08G63/664 ,  C08L71/02 ,  C08L39/06

    摘要： The instant invention relates to a composition comprising at least one polymer having the structure A-B-A′, wherein A and A′ may be the same or different and each is a degradable polyester component and wherein B is the reaction product resulting from the reaction between a diol, having one or more pendant oligomeric or polymeric groups, and A and A′.Additionally, the invention also relates to the development of a bioresorbable patch comprising: (a) an adhesion barrier component comprising a composition according to the invention in the form of a film; and (b) an adhesive component comprising: (i) at least one synthetic adhesive polymer; and/or (ii) at least one polysaccharide. The present invention provides a method of wound healing, comprising administering the composition or patch.

    摘要翻译： 本发明涉及包含至少一种具有结构AB-A'的聚合物的组合物，其中A和A'可以相同或不同，并且各自是可降解的聚酯组分，其中B是由下列反应产生的反应产物： 具有一个或多个侧链低聚或聚合基团的二醇，以及A和A'。 另外，本发明还涉及生物可再吸收贴片的开发，其包括：（a）包含薄膜形式的根据本发明的组合物的粘合屏障组分; 和（b）粘合剂组分，其包含：（i）至少一种合成粘合剂聚合物; 和/或（ii）至少一种多糖。 本发明提供一种伤口愈合的方法，包括施用所述组合物或贴剂。

    ANTIMICROBIAL POLYMERS AND THEIR USES
    2.
    发明申请
    ANTIMICROBIAL POLYMERS AND THEIR USES 审中-公开
    抗微生物聚合物及其用途

    公开(公告)号：US20110124772A1

    公开(公告)日：2011-05-26

    申请号：US12994836

    申请日：2009-05-26

    申请人： Shanger Wang ,  Robert S. Ward ,  Yuan Tian ,  Li Li ,  Keith Mccrea ,  James Parakka ,  Robert L. Jones, JR.

    发明人： Shanger Wang ,  Robert S. Ward ,  Yuan Tian ,  Li Li ,  Keith Mccrea ,  James Parakka ,  Robert L. Jones, JR.

    IPC分类号： C09D175/04 ,  C08G71/04

    CPC分类号： A01N33/12 ,  A01N47/44 ,  A01N25/10 ,  A01N2300/00

    摘要： Polymers with non-leaching antimicrobial activity and their use as surface coatings or bulk resins for medical devices. The antimicrobial polymers are prepared with antimicrobial moieties covalently bonded to a polymer chain end or to a polymer backbone at a side chain end. The antimicrobial moiety-containing endgroups include surface active (or surface assembling) moieties which promote enrichment of antimicrobial endgroups at the polymer surface and thus formation of an antimicrobially active surface. Polymers with built-in antimicrobial endgroups can be used as bulk resins, as antimicrobial additives, or as infection preventative coatings in the manufacture of medical devices (e.g., catheters, vascular access devices, peripheral lines, IV sites, drains, gastric feeding and tubes, and other implantable devices). Such materials can also be used as antimicrobial and antifouling coatings on structures in contact with microorganism in environments that require control of biofilm formation, such as marine products.

    摘要翻译： 具有非浸出抗菌活性的聚合物及其用作医疗器械的表面涂层或体积树脂。 抗微生物聚合物通过共价键合到聚合物链末端的抗微生物部分或在侧链末端与聚合物主链一起制备。 含抗微生物部分的端基包括表面活性（或表面组装）部分，其促进抗微生物端基在聚合物表面的富集，从而形成抗微生物活性表面。 具有内置抗微生物端基的聚合物可用作散装树脂，作为抗微生物添加剂，或作为医疗器械制造中的感染预防性涂层（例如，导管，血管通路装置，外围线，IV部位，下水道，胃饲和管 ，和其他可植入装置）。 在需要控制生物膜形成的环境中，例如海产品，这些材料也可用作与微生物接触的结构上的抗微生物和防污涂料。

    Bis-anthracenyl chiroptical compositions
    3.
    发明授权
    Bis-anthracenyl chiroptical compositions 失效
    双蒽烯基手性组合物

    公开(公告)号：US07679078B2

    公开(公告)日：2010-03-16

    申请号：US11078965

    申请日：2005-03-10

    申请人： Robert R. Schumaker ,  James J. Marek, Jr. ,  James Parakka

    发明人： Robert R. Schumaker ,  James J. Marek, Jr. ,  James Parakka

    IPC分类号： H01L29/08 ,  C07D339/02

    CPC分类号： C07D339/00

    摘要： Optoelectronic materials are provided that are bistable organic tautomeric compositions that intraconvert dithio or diseleno carbamate esters and cyclic 1,3-dithia- or -diselena-2-iminium salts of π-conjugated bis-anthracenyl compounds. Specifically disclosed are compounds having the formula: where X is sulfur or selenium; where the R and R1 groups are alkyl or alkyl that together form a ring of carbon atoms; where An is the anion of a strong acid; and where the Z element is a chiral ring-completing system of atoms that changes chirality on tautomerization. These molecules are in themselves molecular-sized optoelectronic switching devices.

    摘要翻译： 提供了光电材料，其是双稳态有机互变异构体，其包含二硫代氨基甲酸酯或二硒代氨基甲酸酯和环状1,3-二硫或 - 联苯胺-2-亚胺鎓盐和共轭双 - 蒽基化合物。 具体公开的是具有下式的化合物：其中X是硫或硒; 其中R和R 1基团是一起形成碳原子环的烷基或烷基; 其中An是强酸的阴离子; 并且其中Z元素是在互变异构化上改变手性的原子的手性环完成体系。 这些分子本身就是分子尺寸的光电开关器件。

    Bis-anthracenyl chiroptical compositions
    4.
    发明申请
    Bis-anthracenyl chiroptical compositions 失效
    双蒽烯基手性组合物

    公开(公告)号：US20060202193A1

    公开(公告)日：2006-09-14

    申请号：US11078965

    申请日：2005-03-10

    申请人： Robert Schumaker ,  James Marek ,  James Parakka

    发明人： Robert Schumaker ,  James Marek ,  James Parakka

    IPC分类号： H01L29/08 ,  C07D339/02

    CPC分类号： C07D339/00

    摘要： Optoelectronic materials are provided that are bistable organic tautomeric compositions that intraconvert dithio or diseleno carbamate esters and cyclic 1,3-dithia- or -diselena-2-iminium salts of π-conjugated bis-anthracenyl compounds. Specifically disclosed are compounds having the formula: where X is sulfur or selenium; where the R and R1 groups are alkyl or alkyl that together form a ring of carbon atoms; where An is the anion of a strong acid; and where the Z element is a chiral ring-completing system of atoms that changes chirality on tautomerization. These molecules are in themselves molecular-sized optoelectronic switching devices.

    摘要翻译： 提供了光电子材料，其是双键有机互变异构体，其包含二硫代或二硒代氨基甲酸酯和π-共轭双 - 蒽基化合物的环状1,3-二硫或 - 二烯 - 亚胺鎓盐。 具体公开的是具有下式的化合物：其中X是硫或硒; 其中R和R 1个基团是一起形成碳原子环的烷基或烷基; 其中A N是强酸的阴离子; 并且其中Z元素是在互变异构化上改变手性的原子的手性环完成体系。 这些分子本身就是分子尺寸的光电开关器件。

    Control of polymer surface molecular architecture via amphipathic endgroups
    7.
    发明申请
    Control of polymer surface molecular architecture via amphipathic endgroups 有权
    通过两亲性端基控制聚合物表面分子结构

    公开(公告)号：US20050282997A1

    公开(公告)日：2005-12-22

    申请号：US11211734

    申请日：2005-08-26

    申请人： Robert Ward ,  Keith McCrea ,  Yuan Tian ,  James Parakka

    发明人： Robert Ward ,  Keith McCrea ,  Yuan Tian ,  James Parakka

    IPC分类号： A61L27/14 ,  A61L27/18 ,  A61L29/06 ,  A61L31/06 ,  C08F20060101 ,  C08F2/00 ,  C08G18/08 ,  C08G18/12 ,  C08G18/28 ,  C08G18/50 ,  C08G18/62 ,  C08G18/67 ,  C08G65/00 ,  C08G65/329 ,  C08G69/08 ,  C08J5/00 ,  C08L53/00

    CPC分类号： C08G18/6287 ,  A61L27/18 ,  A61L29/06 ,  A61L31/06 ,  C08G18/0823 ,  C08G18/12 ,  C08G18/283 ,  C08G18/2865 ,  C08G18/289 ,  C08G18/5024 ,  C08G18/5039 ,  C08G18/6283 ,  C08G18/6795 ,  C08L75/04 ,  C08G18/3228

    摘要： Polymers whose surfaces are modified by endgroups that include amphipathic surface-modifying moieties. An amphipathic endgroup of a polymer molecule is an endgroup that contains at least two moieties of significantly differing composition, such that the amphipathic endgroup spontaneously rearranges its positioning in a polymer body to position the moiety on the surface of the body, depending upon the composition of the medium with which the body is in contact, when that re-positioning causes a reduction in interfacial energy. An example of an amphipathic surface-modifying endgroup is one that has both a hydrophobic moiety and a hydrophilic moiety in a single endgroup. For instance, a hydrophilic poly(ethylene oxide) terminated with a hydrophilic hydroxyl group is not surface active in air when the surface-modifying endgroup is bonded to a more hydrophobic base polymer. If the hydroxyl group on the oligomeric poly(ethylene oxide) is replaced by a hydrophobic methoxy ether terminus, the poly(ethylene oxide) becomes surface active in air, and allows the poly(ethylene oxide) groups to crystallize in the air-facing surface. In this example, immersion in water destroys the crystallinity as the poly(ethylene oxide) sorbs water and the hydrophobic methoxy group retreats below the surface of the polymer. Also disclosed are methods and articles of manufacture that make use of these polymers.

    摘要翻译： 其表面被包括两亲表面改性部分的端基修饰的聚合物。 聚合物分子的两亲端基是含有至少两个具有显着不同组成的部分的端基，使得两亲性端基在聚合物体中自发地重排其定位，以将该部分定位在身体的表面上，这取决于 当该重新定位导致界面能量降低时，与身体接触的介质。 两亲性表面改性端基的实例是在单个端基具有疏水部分和亲水部分的实例。 例如，当表面改性端基键合到更疏水的基础聚合物上时，用亲水羟基封端的亲水性聚（环氧乙烷）在空气中不是表面活性的。 如果低聚聚（环氧乙烷）上的羟基被疏水性甲氧基醚末端所代替，则聚（环氧乙烷）在空气中变得表面活性，并允许聚（环氧乙烷）基团在面向空气的表面中结晶 。 在该实施例中，当聚（环氧乙烷）吸附水和疏水性甲氧基在聚合物表面下方退缩时，浸入水中会破坏结晶度。 还公开了利用这些聚合物的方法和制品。