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    Hansenula polymorpha yapsin deficient mutant strain and process for the preparation of recombinant proteins using the same
    3.
    发明授权
    Hansenula polymorpha yapsin deficient mutant strain and process for the preparation of recombinant proteins using the same 有权
    汉逊酵母多形态突变体缺陷型突变株及其制备方法

    公开(公告)号：US07262287B2

    公开(公告)日：2007-08-28

    申请号：US10518377

    申请日：2003-06-28

    申请人： Hyun-Ah Kang ,  Sang-Ki Rhee ,  Min-Jeong Sohn ,  Jeong-Yoon Kim

    发明人： Hyun-Ah Kang ,  Sang-Ki Rhee ,  Min-Jeong Sohn ,  Jeong-Yoon Kim

    IPC分类号： C12N15/57 ,  C12N1/15 ,  C12N9/58 ,  C12N15/81 ,  C12N15/01

    CPC分类号： C12N9/58 ,  C07K2319/02 ,  C12N15/815 ,  C12P21/02 ,  C12P21/06

    摘要： The present invention relates to a nucleic acid molecule comprising the HpYPS1 gene encoding H. polymorpha yapsin1, a polypeptide encoded by the nucleic acid molecule, a H. polymorpha mutant strain having reduced yapsin activity by mutation of the HpYPS gene encoding H. polymorpha yapsin1, a recombinant H. polymorpha strain expressing a foreign protein produced by introducing a gene encoding the foreign protein into the H. polymorpha mutant strain, and a process for preparing a foreign protein comprising culturing the recombinant H. polymorpha strain under conditions to express the foreign protein and isolating the foreign protein from the culture.

    摘要翻译： 本发明涉及包含编码多形汉逊酵母多肽1的HpYPS1基因的核酸分子，由核酸分子编码的多肽，通过编码多形汉逊酵母多肽的hpYPS基因的突变而具有降低的yapsin活性的多形汉逊酵母突变菌株， 通过将编码外来蛋白质的基因导入多形汉逊酵母突变菌株而产生的外源蛋白质的重组多形汉逊酵母菌株，以及制备外源蛋白质的方法，包括在表达外源蛋白质的条件下培养重组多形汉逊酵母菌 并从培养物中分离外源蛋白质。

    Infinitely variable speed transmission
    5.
    发明授权
    Infinitely variable speed transmission 失效
    无级变速传动

    公开(公告)号：US5876299A

    公开(公告)日：1999-03-02

    申请号：US737744

    申请日：1996-11-21

    申请人： Man Shik Kim ,  Jeong Cheol Kim ,  Tae Kwan Eum ,  Young Deok Choi ,  Kyeong Hwan Kim ,  In Wook Yeo ,  Jeong Yoon Kim

    发明人： Man Shik Kim ,  Jeong Cheol Kim ,  Tae Kwan Eum ,  Young Deok Choi ,  Kyeong Hwan Kim ,  In Wook Yeo ,  Jeong Yoon Kim

    IPC分类号： F16H37/08 ,  F16H15/16 ,  F16H37/02

    CPC分类号： F16H37/0853 ,  F16H2037/088

    摘要： Disclosed is an infinitely variable speed transmission, including: a speed changing mechanism for primarily changing power from an engine into a necessary speed ratio, including: a sun gear disposed on an input shaft for transmitting power generated from the engine; a plurality of planet rollers which are disposed around the sun gear at a predetermined distance from each other, each planet roller having a truncated cone-shape and being revolvable around the sun gear and rotatable about its axis; a carrier for connecting the planet rollers with each other; a movable ring disposed to be circumscribed on outer tangential line of the planet rollers and movable by moving member along a longitudinal direction of the planet rollers to change a rotational speed of the planet rollers by varying an operating diameter so that an output speed outputted through the carriers connecting the planet roller with each other can be varied; and a second speed changing mechanism for changing the output speed from the speed changing mechanism as a necessary final output speed, including: low and high speed control members which are selectively connected with the first speed changing mechanism.

    摘要翻译： PCT No.PCT / KR96 / 00038 Sec。 371日期：1996年11月21日 102（e）日期1996年11月21日PCT 1996年3月22日PCT公布。 出版物WO96 / 30672 日期：1996年10月3日公开是一种无级变速传动装置，包括：一个用于将发动机功率主要变化为必要变速比的变速机构，包括：一个设置在输入轴上用于传递从发动机产生的动力的太阳齿轮; 多个行星轮，其以恒定的距离设置在所述太阳齿轮周围，每个行星轮具有截头圆锥形状并围绕所述太阳齿轮可旋转并可围绕其轴线旋转; 用于将行星辊彼此连接的载体; 可移动环，设置成围绕行星辊的外切线并且可以通过移动构件沿着行星轮的纵向移动，以通过改变操作直径来改变行星轮的旋转速度，从而通过 可以改变将行星辊彼此连接的载体; 以及用于将输出速度从变速机构改变为必要的最终输出速度的第二变速机构，包括：选择性地与第一变速机构连接的低速和高速控制构件。