摘要:
An over-the-needle peel-away sheath catheter introducer for receiving the distal end of a catheter is formed of a hub having left and right halves with a wing extending transversely from each half. The hub defines between these halves a passageway for a catheter, where the passageway has sides defined by opposing wall surfaces of said halves, and top and bottom walls extending between these halves. A funnel is situated at the proximal end of the hub and a sheath is situated at the distal end of the hub. The funnel, hub and sheath have respective lumens which are aligned forming a continuous passageway. The funnel, hub and sheath furthermore have tear lines along their top and bottom surfaces adapting this catheter introducer to be split apart into two halves and discarded after introduction of a catheter therethrough.
摘要:
A method and apparatus for securely displaying and communicating trusted and untrusted internet content via a web browser is described. In a preferred embodiment, the invention is an electronic marketplace system in which auction-related content is displayed in one window of a customer's web browser while item-related content is displayed in a second window of the customer's web browser, such that the auction-related content and the item-related content are substantially prevented from substantially interacting. The invention further provides a method and apparatus for communicating predetermined information between multiple documents opened in multiple web browser windows, where the documents are served from multiple domains.
摘要:
Pyrimidines of formla (1) are described: wherein R1 is a —XR6 group; R2 and R3 which may be the same or different is each a hydrogen or halogen atom or a group selected from an optionally substituted aliphatic, cycloaliphatic, heteroaliphatic, heterocycloaliphatic, —OH, —OR10 [where R10 is an optionally substituted aliphatic, cycloaliphatic, heteroaliphatic, heterocycloaliphatic, aromatic or heteroaromatic group) —SH, —NO2, —CN, —SR10, —COR10, S(O)R10, —SO2R8, —SO2N(R8)(R9), —CO2R8, —CON(R8)(R9), —CSN(R8)(R9), —NH2 or substituted amino group; R4 is a X1R11 group where X1 is a covalent bond or a —C(R12)(R13)— [where each of R12 and R13 is a hydrogen or halogen atom or a hydroxyl, alkyl or haloalkyl group] or —C(O)— group and R11 is an optionally substituted phenyl, thienyl, thiazolyl or indolyl group; R5 is a halogen atom or an alkynyl group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are selective KDR kinase and/or FGFr kinase inhibitors and are of use in the prophylaxis and treatment of disease states associated with angiogenesis
摘要:
A subset of graphical display items, in a set of graphical display items stored in the one or more electronic storage devices, that have not previously been viewed by a user is determined. A graphical display item is selected from a subset of graphical display items. The graphical display item may be selected according to an order, or selected randomly. An initial display item and the selected graphical display item are electronically transmitted to a user computing device. The initial display item and the selected graphical display item are configured such that the selected graphical display item is displayed on a display device of the user computing device in response to the user selecting the initial display item when the initial display item is displayed on the display device.
摘要:
A subset of graphical display items, in a set of graphical display items stored in the one or more electronic storage devices, that have not previously been viewed by a user is determined. A graphical display item is selected from a subset of graphical display items. The graphical display item may be selected according to an order, or selected randomly. An initial display item and the selected graphical display item are electronically transmitted to a user computing device. The initial display item and the selected graphical display item are configured such that the selected graphical display item is displayed on a display device of the user computing device in response to the user selecting the initial display item when the initial display item is displayed on the display device.
摘要:
A system and methods that enables the determination of the location of a device using a network fingerprint of a known location on the electrical grid. A collection of communication based information is utilized to construct a network fingerprint that is subsequently used to determine whether a device is at a previously known or unknown location. By detecting differences in some or all of this set of information, a system determines whether an electric car has moved from one known location to another or otherwise left a known location. Determining a change in the location of a device, the device or a server take further actions, such as: notifying a user, notifying another server, initiating a configuration process, or operating in different modes. Knowledge about network location assist with assessing the overall load characteristics of a given area of a power grid, and with determining billing related matters.
摘要:
A series of thieno[2,3-b]pyridin-6(7H)-one derivatives, substituted in the 2-position by a carbonyl- or sulfonyl-linked pyrrolidin-3-yl, pyrrolidin-3-ylamino or related moiety, being inhibitors of p38 MAP kinase, are accordingly of use in medicine, for example in the treatment and/or prevention of immune or inflammatory disorders.
摘要:
Compounds of formula (1) are described in which Ra and Rb is each independently a hydrogen atom or a group Rc, or Ra and Rb together form an oxo (═O) or thio (═S) group; X is a N atom or an optionally substituted CH group: Y is a —O— or —S— atom or —SO— or —SO2— group or an optionally substituted —CH2— or —NH— group with the proviso that when Ra and Rb together form an oxo (═O) or thio (═S) group Y is an optionally substituted —CH2— or —NH-group; L1 is a covalent bond or a linker atom or group; p is zero or the integer 1; Alk1 is an optionally substituted C1-10aliphatic or C1-10heteroaliphatic chain; n is zero the integer 1, 2 or 3 with the proviso that when n is zero Y is an optionally substituted —CH2— group: Ar is an optionally substituted C6-12aromatic or C1-9heteroaromatic group; m is zero or the integer 1, 2 or 3; q is zero or the integer 1 or 2; R1, Rc and Rd are hydrogen atoms or the substituents described in the patent specification; and the salts, solvates, hydrates and N-oxides thereof. The compounds are potent and selective inhibitors of p38 kinase and are useful in the treatment of immune or inflammatory disorders.
摘要:
A safety system particularly for a transport service software application. The system integrates into an existing transport service software application communicates with a cellular network mobile device of a transport service driver or at least one passenger located in a vehicle offering rideshare services. In an emergency, a user of the system may press a panic button on the application. The mobile device activates its camera and microphone turns on to livestreams audio and video to emergency personnel, and transmits GPS data to said emergency personnel.