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    Integration of meningococcal conjugate vaccination
    1.
    发明授权
    Integration of meningococcal conjugate vaccination 有权
    脑膜炎球菌结合疫苗的整合

    公开(公告)号：US09402915B2

    公开(公告)日：2016-08-02

    申请号：US11587170

    申请日：2005-04-29

    申请人： Cameron John Marshall

    发明人： Cameron John Marshall

    IPC分类号： A61K47/48 ,  A61K39/00 ,  A61K39/385 ,  A61K39/095

    CPC分类号： A61K39/095 ,  A61K39/092 ,  A61K39/102 ,  A61K39/385 ,  A61K47/646 ,  A61K2039/545 ,  A61K2039/55505 ,  A61K2039/575 ,  A61K2039/6037 ,  A61K2039/70

    摘要： Conjugated meningococcal capsular saccharides will be introduced into immunization schedules in the near future, but the phenomenon of “carrier suppression” must first be addressed, particularly where multiple conjugates are to be used. It has been found that diphtheria toxoid and its derivatives (such as CRM197) can safely be used as the carrier protein, even where multiple meningococcal conjugates are administered at the same time and where a patient has previously been exposed to the carrier protein, either in the form of a previous immunogen (e.g. in a DTP vaccine) or as a previous carrier protein (e.g. in a Hib or pneumococcal conjugate vaccine). The invention provides a method for immunizing a patient, comprising administering multiple conjugates of meningococcal capsular saccharides, wherein each conjugate comprises a diphtheria toxoid (or derivative thereof) carrier protein, and the capsular saccharide, and wherein the patient has been pre-immunized with a diphtheria toxoid (or derivative thereof).

    摘要翻译： 共同的脑膜炎球菌荚膜糖在不久的将来将被引入免疫计划，但是必须首先解决“载体抑制”的现象，特别是在使用多个共轭物的情况下。 已经发现，白喉类毒素及其衍生物（例如CRM197）可以安全地用作载体蛋白，即使在同时施用多个脑膜炎球菌共轭物并且其中患者先前已经暴露于载体蛋白的情况下， 先前的免疫原的形式（例如在DTP疫苗中）或作为先前的载体蛋白（例如在Hib或肺炎球菌结合疫苗中）。 本发明提供了一种用于免疫患者的方法，包括施用脑膜炎球菌荚膜糖的多种缀合物，其中每个缀合物包含白喉类毒素（或其衍生物）载体蛋白和荚膜糖，并且其中所述患者已经用 白喉类毒素（或其衍生物）。

    System and method using a simplified XML format for real-time content publication
    2.
    发明授权
    System and method using a simplified XML format for real-time content publication 有权
    系统和方法使用简化的XML格式进行实时内容发布

    公开(公告)号：US09373102B2

    公开(公告)日：2016-06-21

    申请号：US13195654

    申请日：2011-08-01

    申请人： Sameer Merchant ,  Gerald Bueshel ,  Jules Michael McLeod ,  John Marshall

    发明人： Sameer Merchant ,  Gerald Bueshel ,  Jules Michael McLeod ,  John Marshall

    IPC分类号： G06Q10/10 ,  H04L12/58 ,  H04L12/18

    CPC分类号： H04L51/066 ,  G06Q10/107 ,  H04L12/1868 ,  H04L12/1877 ,  H04L12/1895 ,  H04L51/30 ,  H04L67/02

    摘要： A system and method for delivering content in real-time using advanced messaging technology that reduces the risk of content being lost or dropped in transmission. The system and method utilize a custom, simplified XML format to deliver real-time textual, numeric, and metadata content directly to subscribers. The XML tag set specifies all of the information needed to package, process, and distribute real-time content messages and includes an advanced tagging structure that allows granular content customization. Messages are built on the fly using multi-channel data processing techniques. The XML delivery system and method offers an array of real-time market-specific page-based “Alert” services and aggregated newswires with accompanying real-time numeric data feeds. These feeds contain proprietary assessments and other price data across a broad spectrum of global and regional commodity markets, including oil, petrochemicals, metals, electric power, natural gas, coal, and risk.

    摘要翻译： 一种使用先进消息传递技术实时传送内容的系统和方法，可降低内容在传输中丢失或丢失的风险。 该系统和方法利用自定义的简化XML格式直接向用户提供实时文本，数字和元数据内容。 XML标签集指定了包装，处理和分发实时内容消息所需的所有信息，并包括允许细粒度内容自定义的高级标记结构。 使用多通道数据处理技术即时构建消息。 XML传递系统和方法提供了一系列实时的基于市场的基于页面的“警报”服务和聚合新闻线以及附带的实时数字数据。 这些饲料包含广泛的全球和区域商品市场的专有评估和其他价格数据，包括石油，石化，金属，电力，天然气，煤炭和风险。

    Multi-function condiment container
    3.
    发明授权
    Multi-function condiment container 有权
    多功能调味品容器

    公开(公告)号：US09061796B2

    公开(公告)日：2015-06-23

    申请号：US12766164

    申请日：2010-04-23

    申请人： Craig S. Caldwell ,  John Marshall ,  William F. Rasile

    发明人： Craig S. Caldwell ,  John Marshall ,  William F. Rasile

    IPC分类号： B29D22/00 ,  B65D21/02 ,  B65D75/32 ,  B65D85/72

    CPC分类号： B65D21/0202 ,  B65D75/326 ,  B65D85/72 ,  B65D2221/00 ,  B65D2313/00

    摘要： A container for condiments includes a container portion having generally planar bottom, a generally parallel flange, a discharge spout, and a sidewall extending between the bottom and the flange. A generally planar cover portion is secured to the flange by an adhesive such that there exists a non-bonded region between the cover and the flange. At least one section of the flange in the non-bonded region is bent downwardly away from the cover portion to form therebetween a finger-access gap. The sidewall includes a front portion disposed below the spout and extending downwardly with respect thereto. The sidewall front portion is configured to prevent the spout from becoming displaced upwardly in response to the sidewall front portion being contacted by the rear portion of another container in a package of the containers.

    摘要翻译： 用于调味品的容器包括具有大致平坦的底部的容器部分，大致平行的凸缘，排出口以及在底部和凸缘之间延伸的侧壁。 大致平坦的盖部分通过粘合剂固定到凸缘上，使得在盖和凸缘之间存在非接合区域。 非接合区域中的凸缘的至少一个部分从盖部分向下弯曲，从而在其间形成手指进入间隙。 侧壁包括设置在喷嘴下方并相对于喷嘴向下延伸的前部。 侧壁前部构造成防止喷口响应于侧壁前部与容器的包装中的另一容器的后部接触而向上移位。

    Superconducting switch operation
    4.
    发明授权
    Superconducting switch operation 失效
    超导开关操作

    公开(公告)号：US08680716B2

    公开(公告)日：2014-03-25

    申请号：US12680888

    申请日：2008-10-07

    申请人： Shaohai Zhang ,  Alexander John Marshall ,  Antonis Chris Marshall

    发明人： Shaohai Zhang ,  Alexander John Marshall ,  Antonis Chris Marshall

    IPC分类号： H01H47/00

    CPC分类号： H02H7/001 ,  H01F6/02 ,  H01L39/16 ,  Y02E40/68 ,  Y10T307/76

    摘要： A method of operating a superconducting switch system to protect against quenching in a superconducting magnet circuit is provided. The system comprises a magnet circuit, a main superconducting switch and an auxiliary superconducting switch connected in parallel thereto by low resistance connecting parts. In an initial magnet energisation procedure, after establishing superconducting flow in the circuit, the main and auxiliary switches are closed to cause current to persist in the circuit without further power input. If the main switch quenches, the current will transfer to the auxiliary switch through the resistive connecting parts. Upon restoring the main switch to the superconducting state, the voltage drop through the resistive connecting parts will drive the current back through the main switch. A preconditioning procedure is carried out as part of the magnet energisation procedure to ensure that opening the main switch will establish superconducting current through the auxiliary switch.

    摘要翻译： 提供了一种在超导磁体电路中操作超导开关系统以防止淬火的方法。 该系统包括通过低电阻连接部件并联连接的磁体电路，主超导开关和辅助超导开关。 在初始磁通激励过程中，在电路中建立超导流之后，主开关和辅助开关闭合，导致电流持续在电路中，无需进一步的电源输入。 如果主开关熄火，电流将通过电阻连接部分转移到辅助开关。 在将主开关恢复到超导状态时，通过电阻连接部分的电压降将通过主开关驱动电流。 作为磁通激励程序的一部分进行预处理程序，以确保打开主开关将通过辅助开关建立超导电流。

    Retinal regeneration
    5.
    发明授权
    Retinal regeneration 有权
    视网膜再生

    公开(公告)号：US08562595B2

    公开(公告)日：2013-10-22

    申请号：US12446677

    申请日：2007-10-25

    申请人： Malcolm Plunkett ,  Aly Hussain ,  John Marshall

    发明人： Malcolm Plunkett ,  Aly Hussain ,  John Marshall

    IPC分类号： A61B18/18

    CPC分类号： A61F9/008 ,  A61F9/00821 ,  A61F2009/00863

    摘要： A method of retinal regeneration which improves retinal function by reversal of the degradation of the transport properties of Bruch's membrane. The method involves irradiation through the cornea of the eye to the retinal pigmented epithelium by a laser pulse or sequence of laser pulses having a pulse duration in the range of 10 ps to 20 μs and at a wavelength in the range of about 500 nm to 900 nm. The method applies a radiant exposure which results in the damaging or altering of the retinal pigmented epithelium cells in such a manner as to trigger cellular responses which improve the hydraulic conductivity of Bruch's membrane without causing irreversible damage to adjacent retinal structures and layers.

    摘要翻译： 视网膜再生的方法通过逆转Bruch膜转运性能的降低来改善视网膜功能。 该方法包括通过激光脉冲或脉冲序列的脉冲持续时间在10ps至20微米的范围内并且在约500nm至900nm的波长范围内通过眼睛的角膜照射到视网膜色素上皮 nm。 该方法应用辐射暴露，其导致视网膜色素上皮细胞的损伤或改变，以触发细胞反应，其改善Bruch膜的水力传导性，而不会对相邻的视网膜结构和层造成不可逆的损伤。

    Techniques for reducing thread overhead for systems with multiple multi-threaded processors
    7.
    发明授权
    Techniques for reducing thread overhead for systems with multiple multi-threaded processors 有权
    用于减少具有多个多线程处理器的系统的线程开销的技术

    公开(公告)号：US08453147B2

    公开(公告)日：2013-05-28

    申请号：US11446609

    申请日：2006-06-05

    申请人： Robert Jeter ,  John Marshall ,  William Lee ,  Trevor Garner

    发明人： Robert Jeter ,  John Marshall ,  William Lee ,  Trevor Garner

    IPC分类号： G06F9/46

    CPC分类号： G06F9/5027

    摘要： Techniques for processing requests from a processing thread for a shared resource shared among threads on one or more processors include receiving a bundle of requests from a portion of a thread that is executed during a single wake interval on a particular processor. The bundle includes multiple commands for one or more shared resources. The bundle is processed at the shared resource(s) to produce a bundle result. The bundle result is sent to the particular processor. The thread undergoes no more than one wake interval to sleep interval cycle while the bundle commands are processed at the shared resource(s). These techniques allow a lock for shared resource(s) to be obtained, used and released all while the particular thread is sleeping, so that locks are held for shorter times than in conventional approaches. Using these techniques, line rate packet processing is more readily achieved in routers with multiple multi-threaded processors.

    摘要翻译： 用于处理来自处理线程的用于在一个或多个处理器上的线程之间共享的共享资源的请求的技术包括从在特定处理器上的单个唤醒间隔期间执行的线程的一部分接收一束请求。 捆绑包包含一个或多个共享资源的多个命令。 在共享资源处理捆绑包以产生捆绑结果。 捆绑结果发送到特定的处理器。 线程经历不超过一个唤醒间隔到休眠间隔周期，而束命令在共享资源处被处理。 这些技术允许在特定线程正在休眠期间获得，使用和释放共享资源的锁定，使得锁比一般方法保持更短的时间。 使用这些技术，在具有多个多线程处理器的路由器中更容易实现线路速率分组处理。