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公开(公告)号：US06416870B1
公开(公告)日：2002-07-09
申请号：US09627708
申请日：2000-07-28
IPC分类号： B32B1504
CPC分类号： C23C28/044 , C23C16/402 , C23C16/405 , C23C16/453 , C23C28/04 , Y02T50/67 , Y10T428/265
摘要： A corrosion-resistant coating for a substrate is described. The corrosion-resistant coating comprises a first distinct layer of a first composition disposed over the substrate, wherein the first distinct layer has a thickness that is not greater than about 10 microns, and a second distinct layer of a second composition disposed over the first distinct layer, wherein the second distinct layer has a thickness that is not greater than about 10 microns and either the first distinct layer or the second distinct layer is corrosion-resistant. Preferably, the thickness of each distinct layer is less than about 1 or 2 microns, more preferably, less than about 0.4 microns. The coating may comprise additional layers. Corrosion-resistant articles, methods of protecting an articles, and methods of depositing corrosion-resistant coatings are also described.
摘要翻译： 描述了用于基底的耐腐蚀涂层。 所述耐腐蚀涂层包括设置在所述基底上的第一组合物的第一不同层，其中所述第一不同层具有不大于约10微米的厚度，以及设置在所述第一不同层上的第二组合物的第二不同层 层，其中所述第二不同层具有不大于约10微米的厚度，并且所述第一不同层或所述第二不同层是耐腐蚀的。 优选地，每个不同层的厚度小于约1或2微米，更优选小于约0.4微米。 涂层可以包括另外的层。 还描述了耐腐蚀制品，保护制品的方法和沉积耐腐蚀涂层的方法。
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公开(公告)号：US06214473B1
公开(公告)日：2001-04-10
申请号：US09078123
申请日：1998-05-13
IPC分类号： B32B900
CPC分类号： C23C28/044 , C23C16/402 , C23C16/405 , C23C16/453 , C23C28/04 , Y02T50/67 , Y10T428/265
摘要： A corrosion-resistant coating for a substrate is described. The corrosion-resistant coating comprises a first distinct layer of a first composition disposed over the substrate, wherein the first distinct layer has a thickness that is not greater than about 10 microns, and a second distinct layer of a second composition disposed over the first distinct layer, wherein the second distinct layer has a thickness that is not greater than about 10 microns and either the first distinct layer or the second distinct layer is corrosion-resistant. Preferably, the thickness of each distinct layer is less than about 1 or 2 microns, more preferably, less than about 0.4 microns. The coating may comprise additional layers. Corrosion-resistant articles, methods of protecting an articles, and methods of depositing corrosion-resistant coatings are also described.
摘要翻译： 描述了用于基底的耐腐蚀涂层。 所述耐腐蚀涂层包括设置在所述基底上的第一组合物的第一不同层，其中所述第一不同层具有不大于约10微米的厚度，以及设置在所述第一不同层上的第二组合物的第二不同层 层，其中所述第二不同层具有不大于约10微米的厚度，并且所述第一不同层或所述第二不同层是耐腐蚀的。 优选地，每个不同层的厚度小于约1或2微米，更优选小于约0.4微米。 涂层可以包括另外的层。 还描述了耐腐蚀制品，保护制品的方法和沉积耐腐蚀涂层的方法。
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公开(公告)号：US5964744A
公开(公告)日：1999-10-12
申请号：US316933
申请日：1994-10-03
IPC分类号： A61F2/04 , A61F2/94 , A61L27/34 , A61L27/50 , A61L31/10 , A61L31/14 , A61L31/18 , A61M25/00 , A61M25/04 , A61M25/16
CPC分类号： A61M27/008 , A61L27/34 , A61L27/50 , A61L31/10 , A61L31/14 , A61L31/18 , A61M25/04 , A61F2/94 , A61F2002/041 , A61L2400/16 , A61M2025/0293
摘要： In accordance with the invention, there are provided medical devices with incorporated shape memory systems that allow a polymeric medical device to be inserted in a first conformation or configuration and revert to a second conformation or configuration. The invention is useful in allowing the easy insertion or implantation of a device followed by expansion of the device in order to be retained without expulsion from a body cavity, for example. In another aspect of the invention there is provided a medical device, such as a ureteral stent, that includes comprising an elongated member having a proximal end portion and a distal end portion joined by a body portion. The elongated member has an initial outer diameter. A retention construction serves for retaining the member within a bodily cavity. The member is formulated of a physiologically acceptable polymer capable of hydrating and expanding from the initial member outer diameter to form a final member outer diameter. The device can assume differing shapes and can exhibit different degrees of softening at different places along its length and possess shape memory so that it can be inserted in a first conformation or configuration and revert to a second conformation or configuration upon the occurrence of a triggering event such as hydration.
摘要翻译： 根据本发明，提供了具有结合的形状记忆系统的医疗装置，其允许聚合物医疗装置以第一构象或构型插入并恢复到第二构象或构型。 本发明可用于允许容易地插入或植入装置，然后扩张装置，以便例如在不从体腔排出的情况下保持。 在本发明的另一方面，提供了一种医疗装置，例如输尿管支架，其包括细长构件，该细长构件具有由主体部分连接的近端部分和远端部分。 细长构件具有初始外径。 保持构造用于将构件保持在身体腔内。 该构件配制有能够从初始构件外径水合和膨胀以形成最终构件外径的生理上可接受的聚合物。 该装置可以呈现不同的形状并且可以在其长度上的不同位置显示不同程度的软化，并且具有形状记忆，使得其可以以第一构象或构型插入并且在发生触发事件时恢复到第二构象或构型 如水合。
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公开(公告)号：US5674241A
公开(公告)日：1997-10-07
申请号：US680717
申请日：1996-07-15
CPC分类号： A61F2/07 , A61L31/10 , A61F2/0077 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2250/0067
摘要： The present invention is a medical device such as a stent in the form of an expandable mesh with an expandable polymer layer thereon. The mesh is metal or plastic. The polymer may be any of a variety of expandable polymers, which either expand upon hydration, or expand without significant resistance. The invention may be used, for example, as an expandable biliary, vascular, endotracheal, esophageal, or prostatic device.
摘要翻译： 本发明是一种医疗装置，例如其上具有可膨胀聚合物层的可扩张网状的支架。 网格是金属或塑料。 聚合物可以是各种可膨胀聚合物中的任何一种，其在水合时膨胀或膨胀而没有显着的阻力。 本发明可以用作例如可扩张的胆管，血管，气管内，食管或前列腺装置。
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公开(公告)号：US5599291A
公开(公告)日：1997-02-04
申请号：US274
申请日：1993-01-04
IPC分类号： A61F2/04 , A61F2/94 , A61L27/34 , A61L27/50 , A61L31/10 , A61L31/14 , A61L31/18 , A61M25/00 , A61M25/04 , A61M25/16 , A61M37/00
CPC分类号： A61M27/008 , A61L27/34 , A61L27/50 , A61L31/10 , A61L31/14 , A61L31/18 , A61M25/04 , A61F2/94 , A61F2002/041 , A61M2025/0293
摘要： A ureteral stent comprising an elongated member having a proximal end portion and a distal end portion joined by a body portion. The elongated member has an initial outer diameter. A retention construction serves for retaining the member within the ureter. The member is formulated of a physiologically acceptable polymer capable of hydrating and expanding from the initial member outer diameter to form a final member outer diameter. The stent can assume differing shapes and can exhibit different degrees of softening at different places along its length.
摘要翻译： 输尿管支架，其包括具有近端部分和由主体部分连接的远端部分的细长部件。 细长构件具有初始外径。 保留结构用于将构件保持在输尿管内。 该构件配制有能够从初始构件外径水合和膨胀以形成最终构件外径的生理上可接受的聚合物。 支架可以呈现不同的形状，并且可以在其长度上的不同位置显示不同程度的软化。
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6.发明授权
公开(公告)号：US4223124A
公开(公告)日：1980-09-16
申请号：US51097
申请日：1979-06-22
CPC分类号： C08G63/81
摘要： A method for decreasing the amount of ether as a by-product in polyesters (for example terephthalic-based) by initially utilizing a deficient amount of a glycol (for example, ethylene glycol) in the early reaction stages and utilizing an excess of the glycol in the final or end stages. The polyesters produced are of better quality, have a high melting point, possess increased thermal stability, and yield improved fiber properties.
摘要翻译： 通过在早期反应阶段最初利用不足量的二醇（例如乙二醇）并利用过量的二醇来减少聚酯（例如对苯二甲酸）中副产物的醚的量的方法 在最后阶段或结束阶段。 生产的聚酯具有更好的质量，具有高熔点，具有增加的热稳定性，并且产率提高了纤维性能。
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公开(公告)号：US06779998B2
公开(公告)日：2004-08-24
申请号：US10269757
申请日：2002-10-10
申请人： David Goral , Adel Kafrawy , William F. Polley , Joseph R. Thomas
发明人： David Goral , Adel Kafrawy , William F. Polley , Joseph R. Thomas
IPC分类号： B29C4514
CPC分类号： A61M25/0009 , B29C45/0013 , B29C45/1615 , B29C45/1704 , B29L2031/7542
摘要： An apparatus is disclosed for manufacturing an integral one-piece catheter having a tube and a hub. A mold having a mold cavity into which molten polymer is fed to form the hub and tube, and into which gas is injected into an inlet of the mold.
摘要翻译： 公开了一种用于制造具有管和毂的整体式单件导管的装置。 具有模腔的模具，熔融聚合物进料到其中以形成毂和管，并将气体注入到模具的入口中。
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公开(公告)号：US5968070A
公开(公告)日：1999-10-19
申请号：US909520
申请日：1997-08-11
CPC分类号： A61F2/07 , A61L31/10 , A61F2/0077 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2250/0067
摘要： The present invention is a medical device such as a stent in the form of an expandable mesh with an expandable polymer layer thereon. The mesh is metal or plastic. The polymer may be any of a variety of expandable polymers, which either expand upon hydration, or expand without significant resistance. The invention may be used, for example, as an expandable biliary, vascular, endotracheal, esophageal, or prostatic device.
摘要翻译： 本发明是一种医疗装置，例如其上具有可膨胀聚合物层的可扩张网状的支架。 网格是金属或塑料。 聚合物可以是各种可膨胀聚合物中的任何一种，其在水合时膨胀或膨胀而没有显着的阻力。 本发明可以用作例如可扩张的胆管，血管，气管内，食管或前列腺装置。
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9.发明授权One-piece biocompatible absorbable rivet and pin for use in surgical procedures 失效一体式生物相容性可吸收铆钉和针脚用于外科手术公开(公告)号：US06846313B1
公开(公告)日：2005-01-25
申请号：US09667729
申请日：2000-09-22
申请人： Laurel L. Rogers , Mariann Sayer , David W. Overaker , Shawn T. Huxel , Kevin Cooper , Dennis D. Jamiolkowski , Joseph R. Thomas
发明人： Laurel L. Rogers , Mariann Sayer , David W. Overaker , Shawn T. Huxel , Kevin Cooper , Dennis D. Jamiolkowski , Joseph R. Thomas
CPC分类号： A61B17/68
摘要： A bioabsorbable rivet and pin fastener is formed as an elongated unit that may be used for anchoring, or for attachment of a fixation plate. The rivet has a head mechanically connected to two or more legs that extend generally distally from the head and may flex outwardly from a central rivet axis. The pin is integral with the rivet and oriented along the central axis by a connection such as a web or a plurality of braces, forming an integral, aligned, one-piece assembly that may, for example, be molded as a single piece. The connection breaks under force as the pin is driven into the rivet, so that the pin contacts internal surfaces of the legs and pushes the legs outward into frictional engagement with the surrounding bone. The one-piece assembly may be formed in a gated mold having a central pin with a relief passage that defines the braces between upper and lower portions of the rivet. The braces so formed at the weld line readily part from the mold, and are easily sheared when the pin is advanced during installation of the rivet.
摘要翻译： 生物可吸收的铆钉和销紧固件形成为可用于锚定或用于附接固定板的细长单元。 铆钉具有机械连接到两个或更多个腿的头部，该两个或多个腿部从头部大致向远侧延伸并且可以从中心铆钉轴线向外弯曲。 该销与铆钉成一体并且通过诸如幅材或多个支架的连接件沿着中心轴线定向，形成整体的，对齐的整体式组件，其可以例如被模制成单件。 当销被驱动到铆钉中时，连接断裂，使得销接触腿的内表面并向外推动腿与周围的骨摩擦接合。 一体式组件可以形成在具有中心销的门控模具中，该中心销具有在铆钉的上部和下部之间限定支架的释放通道。 在焊接线处形成的支架容易地与模具成一部分，并且在铆钉安装期间当销前进时容易剪切。
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公开(公告)号：US5156596A
公开(公告)日：1992-10-20
申请号：US650439
申请日：1991-02-04
CPC分类号： A61M25/0606 , A61M25/0097 , A61M39/0693 , A61M2025/0037
摘要： A catheter assembly is provided. An attachment structure has a proximal end portion of an outer cannula attached to it. A needle is insertable through the outer cannula and the attachment structure. An inner cannula is attached to an inner cannula attachment region of the attachment structure. The inner cannula is insertable axially through the attachment structure. The attachment structure can comprise two hubs, one for the outer cannula and the other for the inner cannula, the two hubs being attachable to one another to form the overall attachment structure. A valve structure is associated with the attachment structure, suitably with the outer cannula hub. The valve structure normally closes communication between an access passage in the attachment structure, e.g., in the outer cannula hub, and the outer cannula lumen. The valve structure opens sufficiently for the inner cannula to pass through it and to open communication between the access passage and the outer cannula lumen when the inner cannula is inserted through another passage in the attachment structure and through the outer cannula lumen. The assembly allows the removal of the inner cannula and the insertion of a replacement inner cannula, if desired, without removing the outer cannula from the blood vessel. Use of a relatively small diameter needle for a desired diameter outer cannula can also be provided if the material of the outer cannula is such that it will swell in place.
摘要翻译： 提供导管组件。 附接结构具有附接到其上的外套管的近端部分。 针可以通过外套管和附接结构插入。 内插管附接到附接结构的内插管附接区域。 内套管可轴向地插入穿过附接结构。 附接结构可以包括两个毂，一个用于外套管，另一个用于内插管，两个毂可彼此附接以形成整体附接结构。 阀结构与附接结构相关联，适当地与外套管毂相关联。 瓣膜结构通常封闭连接结构中的通路，例如在外套管套管和外套管内腔之间的连通。 当内套管穿过连接结构中的另一个通道并穿过外套管腔时，阀结构足够开启以使内套管穿过它并打开进入通道和外套管腔之间的连通。 如果需要，组件允许去除内套管和插入置换内套管，而不从血管移除外套管。 如果外套管的材料使其将在适当的位置膨胀，则也可以使用相对较小直径的针头用于所需直径的外插管。
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