公开(公告)号：US07932046B2

公开(公告)日：2011-04-26

申请号：US12317954

申请日：2008-12-31

申请人： Sang Jun Sim ,  Jun Pyo Kim ,  Cheol Hee Park

发明人： Sang Jun Sim ,  Jun Pyo Kim ,  Cheol Hee Park

IPC分类号： C12M1/34 ,  G01N21/00 ,  G01N33/53 ,  G01N33/543

CPC分类号： G01N33/5432 ,  Y10S435/808 ,  Y10S436/829 ,  Y10S436/905

摘要： Provided are a method for detecting biomaterials, a method for fabricating a chip for biomaterial detection and a chip for biomaterial detection. The method for detecting biomaterials is characterized by comprising the steps of: (S1) immobilizing polydiacetylene liposomes onto a substrate; (S2) linking the polydiacetylene liposomes together and layering them on the substrate; (S3) immobilizing a material which forms a complementary binding with a subject biomaterial to be detected onto the polydiacetylene liposomes; (S4) exposing the resulted polydiacetylene liposome to UV light so as to form a chip for biomaterial detection; (S5) applying the subject biomaterial to be detected to the chip for biomaterial detection for reaction; and (S6) measuring a fluorescent signal from the chip for biomaterial detection.

摘要翻译： 提供了生物材料检测方法，生物材料检测用芯片的制造方法以及生物材料检测用芯片。 检测生物材料的方法的特征在于包括以下步骤：（S1）将聚二乙炔脂质体固定在基材上; （S2）将聚二乙炔脂质体连接在一起并将它们层叠在基材上; （S3）将与要检测的受试生物材料形成互补结合的材料固定在聚二乙炔脂质体上; （S4）将得到的聚二乙炔脂质体暴露于紫外光，形成用于生物材料检测的芯片; （S5）将要检测的对象生物材料应用于用于反应的生物材料检测用芯片; 和（S6）测量来自用于生物材料检测的芯片的荧光信号。

公开(公告)号：US20120028267A1

公开(公告)日：2012-02-02

申请号：US13060177

申请日：2009-08-21

申请人： Sang Jun Sim ,  Jun Pyo Kim

发明人： Sang Jun Sim ,  Jun Pyo Kim

IPC分类号： G01N27/00 ,  C12N9/99 ,  C07K14/00 ,  C07H99/00 ,  C07H1/00 ,  C07K1/107 ,  C07K16/00 ,  C07K2/00 ,  B82Y5/00 ,  B82Y15/00

CPC分类号： G01N33/54353 ,  B82Y5/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/174 ,  G01N33/54373 ,  G01N33/54393

摘要： Disclosed is a method of detecting even a very small amount of a target substance by mixing a linker and a spacer at a suitable ratio and immobilizing the mixture on the surface of carbon nanotubes in a carbon nanotube-based biosensor. This method detects a specific substance at the level of femtomoles and lowers the detection limit of conventional carbon nanotube transistor sensors. Accordingly, the method detects even a very small amount of a target substance, and thus the carbon nanotube-based biosensor is a highly useful sensor which can be used either as a medical sensor for diagnosing diseases or as an environmental sensor.

摘要翻译： 公开了通过以适当的比例混合接头和间隔物来均匀检测目标物质的方法，并将该混合物固定在碳纳米管基生物传感器中的碳纳米管表面上。 该方法可以检测飞镖水平的特定物质，降低常规碳纳米管晶体管传感器的检测限。 因此，该方法即使检测到极少量的目标物质，因此基于碳纳米管的生物传感器是可用作诊断疾病的医疗传感器或作为环境传感器的高度有用的传感器。

公开(公告)号：US20110014724A1

公开(公告)日：2011-01-20

申请号：US12867355

申请日：2008-05-26

申请人： Sang Jun Sim ,  Jun Pyo Kim ,  Cuong Cao

发明人： Sang Jun Sim ,  Jun Pyo Kim ,  Cuong Cao

IPC分类号： G01N33/553 ,  B05D1/00 ,  B05D3/10

CPC分类号： G01N33/54346 ,  G01N33/54373

摘要： Disclosed is a method of detecting bioproducts using Localized Surface Plasmon Resonance (LSPR) of gold nanoparticles, which can diagnose bioproducts based on changes in the maximum wavelength occurred by an antigen-antibody reaction after immobilization of the gold nanoparticles onto a glass panel. A sensor using such method exhibits high sensitivity, is low in price, and makes quick diagnosis possible, thereby being applicable to various biological fields associated with environmental contaminants, pathogens and the like, as well as diagnosis of diseases. Further, it provides a technology for manufacturing a sensor having higher sensitivity, low price and quick performance, as compared to conventional methods using SPR.

摘要翻译： 公开了使用金纳米颗粒的局部表面等离子体共振（LSPR）检测生物产物的方法，其可以在将金纳米颗粒固定在玻璃面板上之后基于由抗原 - 抗体反应发生的最大波长的变化来诊断生物产物。 使用这种方法的传感器具有高灵敏度，价格低廉并且使得快速诊断成为可能，从而适用于与环境污染物，病原体等相关的各种生物领域以及疾病的诊断。 此外，与使用SPR的常规方法相比，它提供了用于制造具有更高灵敏度，低价格和快速性能的传感器的技术。

公开(公告)号：US20090291454A1

公开(公告)日：2009-11-26

申请号：US12317954

申请日：2008-12-31

申请人： Sang Jun Sim ,  Jun-Pyo Kim ,  Cheol-Hee Park

发明人： Sang Jun Sim ,  Jun-Pyo Kim ,  Cheol-Hee Park

IPC分类号： G01N33/53 ,  G01N33/543 ,  G01N21/76 ,  C12M1/00

CPC分类号： G01N33/5432 ,  Y10S435/808 ,  Y10S436/829 ,  Y10S436/905

摘要： Provided are a method for detecting biomaterials, a method for fabricating a chip for biomaterial detection and a chip for biomaterial detection. The method for detecting biomaterials is characterized by comprising the steps of: (S1) immobilizing polydiacetylene liposomes onto a substrate; (S2) linking the polydiacetylene liposomes together and layering them on the substrate; (S3) immobilizing a material which forms a complementary binding with a subject biomaterial to be detected onto the polydiacetylene liposomes; (S4) exposing the resulted polydiacetylene liposome to UV light so as to form a chip for biomaterial detection; (S5) applying the subject biomaterial to be detected to the chip for biomaterial detection for reaction; and (S6) measuring a fluorescent signal from the chip for biomaterial detection.

摘要翻译： 提供了生物材料检测方法，生物材料检测用芯片的制造方法以及生物材料检测用芯片。 检测生物材料的方法的特征在于包括以下步骤：（S1）将聚二乙炔脂质体固定在基材上; （S2）将聚二乙炔脂质体连接在一起并将它们层叠在基材上; （S3）将与要检测的受试生物材料形成互补结合的材料固定在聚二乙炔脂质体上; （S4）将得到的聚二乙炔脂质体暴露于紫外光，形成用于生物材料检测的芯片; （S5）将要检测的对象生物材料应用于用于反应的生物材料检测用芯片; 和（S6）测量来自用于生物材料检测的芯片的荧光信号。

公开(公告)号：US20120316908A1

公开(公告)日：2012-12-13

申请号：US13488950

申请日：2012-06-05

申请人： Sung-bum Park ,  Sang-ho Park ,  Jun-pyo Kim ,  Sun-woong Woo

发明人： Sung-bum Park ,  Sang-ho Park ,  Jun-pyo Kim ,  Sun-woong Woo

IPC分类号： G06Q10/06

CPC分类号： G06Q10/0631

摘要： An apparatus and a method for managing a new product and technology introduction based on a work process, are provided. The apparatus includes a display unit configured to display each stage of a project. The apparatus further includes an input unit configured to receive generation request information of a job item in each stage and progress result information indicating completion of the job item in each stage. The apparatus further includes a controller configured to control the display unit to display each stage of the project based on the generation request information and/or the progress result information.

摘要翻译： 提供了一种基于工作过程管理新产品和技术介绍的装置和方法。 该装置包括被配置为显示项目的每个阶段的显示单元。 该装置还包括：输入单元，被配置为接收每个阶段中的作业项目的生成请求信息，以及指示每个阶段中作业项目完成的进度结果信息。 该装置还包括：控制器，被配置为基于生成请求信息和/或进度结果信息来控制显示单元显示项目的每个阶段。