利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

85 条记录 (耗时 0.031 秒)

    Flow Control Technique for Assay Devices
    3.
    发明申请
    Flow Control Technique for Assay Devices 有权
    测定装置的流量控制技术

    公开(公告)号：US20110097734A1

    公开(公告)日：2011-04-28

    申请号：US12968366

    申请日：2010-12-15

    申请人： Shawn Ray Feaster ,  Kaiyuan Yang

    发明人： Shawn Ray Feaster ,  Kaiyuan Yang

    IPC分类号： G01N33/543 ,  C08B1/00

    CPC分类号： G01N33/558 ,  G01N33/52

    摘要： A method for controlling fluid flow in an assay device that employs a membrane is provided. Specifically, one or more recessed regions are formed in the membrane by applying a solvent treatment thereto. The solvent treatment is selected based on its particular dissolving capacity for the material used to form the membrane. For example, an alcohol-based solvent, such as methanol, may be used as a solvent for nitrocellulose membranes. Upon contact with the solvent treatment, a recessed region is formed that may serve a variety of different functions relating to flow control. In one particular embodiment, the recessed region may function as a metering channel that is capable of delivering a controlled volume of the test sample to a detection zone upon initiation of the assay.

    摘要翻译： 提供了一种用于控制采用膜的测定装置中的流体流动的方法。 具体地，通过对膜进行溶剂处理，在膜中形成一个或多个凹陷区域。 基于其用于形成膜的材料的特定溶解能力来选择溶剂处理。 例如，醇类溶剂如甲醇可用作硝酸纤维素膜的溶剂。 在与溶剂处理接触时，形成可以用于与流量控制有关的各种不同功能的凹陷区域。 在一个具体实施方案中，凹陷区域可用作计量通道，其能够在测定开始时将受控体积的测试样品递送到检测区域。

    Luminescent metallic cluster particles and uses thereof
    7.
    发明申请
    Luminescent metallic cluster particles and uses thereof 审中-公开
    发光金属簇粒子及其用途

    公开(公告)号：US20070141727A1

    公开(公告)日：2007-06-21

    申请号：US11304864

    申请日：2005-12-15

    申请人： Lei Huang ,  Kaiyuan Yang ,  Xuedong Song

    发明人： Lei Huang ,  Kaiyuan Yang ,  Xuedong Song

    IPC分类号： G01N33/553

    CPC分类号： G01N33/551 ,  A61K49/0065 ,  A61K49/0093 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1014 ,  C09K2211/1029 ,  C09K2211/188 ,  G01N33/5438 ,  G01N33/553 ,  G01N33/66

    摘要： A luminescent particle having a luminescent core structure formed from at least one type of luminescent metallic cluster complex and a shell that covers said core structure is described. The luminescent core structure includes one or more aggregates of metal cluster complexes. The shell has one or more layers of thin films formed predominately of organic or inorganic polymers, hydrid polymers, or combinations thereof. The luminescent particles can be adapted for optical detection or imaging applications. Methods of fabricating the various iterations of the luminescent particles are also provided.

    摘要翻译： 描述了由至少一种类型的发光金属簇络合物形成的具有发光核心结构的发光颗粒和覆盖所述芯结构的外壳。 发光核心结构包括一个或多个金属簇复合物的聚集体。 壳体具有主要由有机或无机聚合物，杂质聚合物或其组合形成的一层或多层薄膜。 发光颗粒可以适用于光学检测或成像应用。 还提供了制造发光颗粒的各种迭代的方法。

    Edge-stiffened sheet material probe
    8.
    发明申请
    Edge-stiffened sheet material probe 审中-公开
    边缘加强片材探针

    公开(公告)号：US20060243409A1

    公开(公告)日：2006-11-02

    申请号：US11118860

    申请日：2005-04-29

    申请人： Jeffrey Fish ,  Kaiyuan Yang

    发明人： Jeffrey Fish ,  Kaiyuan Yang

    IPC分类号： D21F1/04

    CPC分类号： A61C15/02 ,  A61C2202/00

    摘要： An edge-stiffened sheet material probe is provided. The probe is useful for probing and cleaning of small, constricted or confined spaces. For example, the probe may be suitably used as a dental probe for cleaning interdental spaces. The probe formed from at least one fibrous web material that is cut and sealed to form an edge and terminates at a first point. In addition, the probe may be formed from or as a laminate of two or more fibrous web material layers that are cut and sealed, or may be formed from or as a laminate of the at least one sheet or material may be folded or two or more sheets may be cut and sealed to form. A pack of connected probes is also provided.

    摘要翻译： 提供边缘加强的片材探针。 探头可用于探测和清洁小的，狭窄的或密闭的空间。 例如，探针可以适合用作牙科探针，以清洁齿间空间。 所述探针由至少一个被切割和密封以形成边缘并且终止于第一点的纤维网材料形成。 此外，探针可以由两个或更多个被切割和密封的纤维网材料层的层压体形成，或者可以由至少一个片材的材料形成，或者可以由层叠体形成，或者可以被折叠成两个或两个或 更多的片材可以被切割和密封形成。 还提供一组连接的探头。

    Lateral flow devices using reactive chemistry
    9.
    发明申请
    Lateral flow devices using reactive chemistry 失效
    使用反应化学的侧流装置

    公开(公告)号：US20060205087A1

    公开(公告)日：2006-09-14

    申请号：US11079730

    申请日：2005-03-14

    申请人： Shawn Feaster ,  Kaiyuan Yang

    发明人： Shawn Feaster ,  Kaiyuan Yang

    IPC分类号： G01N33/558

    CPC分类号： G01N33/558 ,  G01N33/583 ,  Y10S435/805 ,  Y10S435/81 ,  Y10S435/97 ,  Y10S436/805 ,  Y10S436/81

    摘要： There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in communication with a wicking pad. The porous membrane has a detection zone which has a chromophore configured to chemically react with an analyte or a secondary trigger or a reaction product from the analyte and a trigger generating reagent(s), to generate a visually detectible signal. Additional chrmophore zones may be located downstream from the first chrmophore zone to generate signals of varying color. Scavenging zones may be included between chromophore zones to attenuate the signal by reacting with the analyte without generating a visually detectable signal.

    摘要翻译： 提供了一种侧流测定装置，用于检测驻留在测试样品中的分析物的存在或数量，其中侧流测定装置具有与芯吸垫连通的多孔膜。 多孔膜具有检测区，其具有配置成与分析物或辅助触发剂或来自分析物和触发产生试剂的反应产物发生化学反应的发色团，以产生视觉上可检测的信号。 另外的chrmophore区域可以位于第一chrmophore区域的下游，以产生变化颜色的信号。 清除区域可以包括在发色团区域之间，以通过与分析物反应来衰减信号，而不产生视觉上可检测的信号。

    Self-contained swab-based diagnostic systems
    10.
    发明授权
    Self-contained swab-based diagnostic systems 有权
    独立的基于拭子的诊断系统

    公开(公告)号：US07098040B2

    公开(公告)日：2006-08-29

    申请号：US10744235

    申请日：2003-12-23

    申请人： Rosann Marie Matthews Kaylor ,  RameshBabu Boga ,  Kaiyuan Yang ,  David Samuel Cohen ,  Herb Velazquez ,  Amanda Lee O'Connor

    发明人： Rosann Marie Matthews Kaylor ,  RameshBabu Boga ,  Kaiyuan Yang ,  David Samuel Cohen ,  Herb Velazquez ,  Amanda Lee O'Connor

    IPC分类号： G01N33/558

    CPC分类号： G01N1/02 ,  C12M33/02 ,  G01N2001/028 ,  Y10S435/81 ,  Y10S435/97 ,  Y10S436/805 ,  Y10S436/81

    摘要： A diagnostic test unit is provided. The test unit comprises a stem having a first end and a second end, the stem defining at least one flow channel extending between the first end and the second end. A swab is disposed at the first end of the stem, the swab being configured to collect a test sample derived from a biological source that is suspected of containing an analyte. The test unit also comprises a fluid chamber configured to contain a fluid, wherein the fluid chamber is in fluid communication with the swab via the flow channel. The test unit also comprises a rupturable seal that inhibits leakage of the fluid from the fluid chamber prior to use, and an assay for detecting the presence or absence of the analyte. The assay is in fluid communication with the swab, the flow channel, and the fluid chamber.

    摘要翻译： 提供诊断测试单元。 测试单元包括具有第一端和第二端的杆，所述杆限定在第一端和第二端之间延伸的至少一个流动通道。 拭子设置在茎的第一端，拭子被配置成收集来自怀疑含有分析物的生物来源的测试样品。 测试单元还包括被配置为容纳流体的流体室，其中流体室经由流动通道与拭子流体连通。 测试单元还包括可破坏的密封，其在使用之前抑制流体从流体室的泄漏，以及用于检测分析物的存在或不存在的测定。 测定与拭子，流动通道和流体室流体连通。