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    Stent with Outer Member to Embolize an Aneurysm
    1.
    发明申请
    Stent with Outer Member to Embolize an Aneurysm 有权
    支架与外部栓塞栓塞动脉瘤

    公开(公告)号：US20160151177A1

    公开(公告)日：2016-06-02

    申请号：US14562725

    申请日：2014-12-07

    Applicant: Robert A. Connor ,  Muhammad Tariq Janjua ,  Mark Knudson

    Inventor： Robert A. Connor ,  Muhammad Tariq Janjua ,  Mark Knudson

    IPC: A61F2/82 ,  A61B17/12

    CPC classification number: A61F2/82 ,  A61B17/12022 ,  A61B17/12118 ,  A61B17/1219 ,  A61B2017/00898 ,  A61B2090/3925 ,  A61F2/91 ,  A61F2002/075 ,  A61F2002/823 ,  A61F2250/0065 ,  A61L31/022 ,  A61L31/10 ,  A61L31/14 ,  A61L31/18 ,  A61L2430/36

    Abstract: This invention is a stent to reduce blood flow to an aneurysm comprising: (a) an inner member, wherein this inner member is expanded from a first configuration to a second configuration within the parent vessel of an aneurysm, wherein the circumference of the second configuration is larger than the circumference of the first configuration; and (b) an outer member, wherein this outer member is less porous than the inner member, wherein this outer member covers or surrounds a first percentage of the surface area of the inner member when the inner structure is in the first configuration, wherein this outer member covers or surrounds a second percentage of the surface area of the inner member when the inner structure is in the second configuration, and wherein the second percentage less than the first percentage.

    Abstract translation: 本发明是一种用于减少血液流向动脉瘤的支架，包括：（a）内部构件，其中该内部构件在动脉瘤的母体容器内从第一构型扩展到第二构造，其中第二构型的周长 大于第一构造的圆周; 和（b）外部构件，其中该外部构件比内部构件多孔，其中当内部构件处于第一构型时，该外部构件覆盖或围绕内部构件的表面积的第一百分比，其中， 当内部结构处于第二构造时，外部构件覆盖或围绕内部构件的表面积的第二百分比，并且其中第二百分比小于第一百分比。

    Neural electrode treatment
    2.
    发明申请
    Neural electrode treatment 有权
    神经电极治疗

    公开(公告)号：US20070043400A1

    公开(公告)日：2007-02-22

    申请号：US11205415

    申请日：2005-08-17

    Applicant: Adrianus Donders ,  Koen Weijand ,  Mark Knudson

    Inventor： Adrianus Donders ,  Koen Weijand ,  Mark Knudson

    IPC: A61N1/00

    CPC classification number: A61N1/36146 ,  A61N1/36053 ,  A61N1/36085 ,  A61N1/36114

    Abstract: An apparatus for applying a signal to a nerve for the treatment of a disorder includes a first electrode and a second electrode. Each of the electrodes is adapted to be secured to a nerve of a patient. A signal generator is electrically connected to each of the first and second electrodes. The signal generator is adapted to create a signal having a first waveform at the first electrode and a second waveform at the second electrode. The waveforms have parameters selected to block propagation of neural action potentials. The waveforms have a repeating pattern of cycles of pulses with a delay period between at least selected ones of said pulses. In one embodiment, the first and second waveforms are out of phase for a cycle of one of the waveforms to occur during a delay period of the other of the waveforms.

    Abstract translation: 用于向神经施加信号以用于治疗病症的装置包括第一电极和第二电极。 每个电极适于固定到患者的神经。 信号发生器电连接到第一和第二电极中的每一个。 信号发生器适于产生在第一电极处具有第一波形的信号和在第二电极处的第二波形。 波形具有选择的参数以阻止神经动作电位的传播。 这些波形具有脉冲周期的重复模式，其中延迟周期至少在所选择的脉冲之间。 在一个实施例中，在另一个波形的延迟周期期间，波形中的一个波形的周期是第一和第二波形异相。

    Injection sleep apnea treatment
    3.
    发明申请
    Injection sleep apnea treatment 有权
    注射睡眠呼吸暂停治疗

    公开(公告)号：US20050268923A1

    公开(公告)日：2005-12-08

    申请号：US11197271

    申请日：2005-08-03

    Applicant: Mark Knudson ,  Katherine Tweden ,  Timothy Conrad

    Inventor： Mark Knudson ,  Katherine Tweden ,  Timothy Conrad

    IPC: A61F2/00 ,  A61F5/56 ,  A61B19/00

    CPC classification number: A61F5/56 ,  A61F2/0059

    Abstract: A patient's upper airway condition such as snoring and sleep apnea is treated by selecting a particulate material selected for limited migration within tissue and for encouraging a fibrotic response of tissue to the material. A bolus of the particulate material is injected into the tissue area to structurally stiffen the tissue.

    Abstract translation: 患者的上呼吸道状况如打鼾和睡眠呼吸暂停通过选择在组织内选择用于有限迁移的颗粒材料并促进组织对该材料的纤维化反应来治疗。 将大量颗粒材料注入组织区域以使组织结构变硬。

    Treatment for sleep apnea or snoring
    4.
    发明申请
    Treatment for sleep apnea or snoring 有权
    治疗睡眠呼吸暂停或打鼾

    公开(公告)号：US20050251255A1

    公开(公告)日：2005-11-10

    申请号：US11179184

    申请日：2005-07-12

    Applicant: Anja Metzger ,  Brian Erickson ,  John Sopp ,  Mark Knudson ,  Timothy Conrad

    Inventor： Anja Metzger ,  Brian Erickson ,  John Sopp ,  Mark Knudson ,  Timothy Conrad

    IPC: A61F2/00 ,  A61F2/20 ,  A61F5/56 ,  A61M31/00 ,  A61M37/00

    CPC classification number: A61F5/56 ,  A61F2/04 ,  A61F2/20 ,  A61F2002/046 ,  A61M31/002 ,  A61M37/00

    Abstract: A pharyngeal airway having a pharyngeal wall of a patient at least partially surrounding and defining the airway is treated by selecting an implant dimensioned so as to be implanted at or beneath a mucosal layer of the pharyngeal wall and extending transverse to said wall. The implant has mechanical characteristics for the implant, at least in combination with a fibrotic tissue response induced by the implant, to stiffen said pharyngeal wall to resist radial collapse. The implant is implanted into the pharyngeal wall transverse to a longitudinal axis of the airway.

    Abstract translation: 具有至少部分地围绕和限定气道的患者的咽壁的咽气道通过选择尺寸设置成植入在咽壁的粘膜层上或下方并且横向于所述壁延伸的植入物来治疗。 植入物具有用于植入物的机械特征，至少与由植入物引起的纤维化组织反应相结合，以加强所述咽壁以抵抗径向塌陷。 将植入物植入到垂直于气道纵轴的咽壁中。

    Controlled vagal blockage therapy
    6.
    发明申请
    Controlled vagal blockage therapy 有权
    受控迷走神经阻滞治疗

    公开(公告)号：US20050038484A1

    公开(公告)日：2005-02-17

    申请号：US10881045

    申请日：2004-06-30

    Applicant: Mark Knudson ,  Richard Wilson ,  Katherine Tweden ,  Timothy Conrad

    Inventor： Mark Knudson ,  Richard Wilson ,  Katherine Tweden ,  Timothy Conrad

    IPC: A61N1/05 ,  A61N1/32 ,  A61N1/34 ,  A61N1/36 ,  A61N1/18

    CPC classification number: A61N1/36085 ,  A61N1/05 ,  A61N1/321 ,  A61N1/36007 ,  A61N1/36053 ,  A61N1/36071 ,  A61N1/36114 ,  A61N1/36178

    Abstract: A method for treating at least one of a plurality of disorders characterized at least in part by vagal activity includes positioning an electrode around a body organ innervated by the vagus. An electrical signal is applied to the electrode to modulate vagal activity. The electrical signal is applied at a frequency selected for the signal to create a neural conduction block to the vagus with the neural conduction block selected to at least partially block nerve impulses on the vagus. The application of the electrical signal is discontinued. The application of the signal and the discontinuing of the signal are repeated with durations of the discontinuing and the application selected to treat the disorder.

    Abstract translation: 用于治疗至少部分由迷走神经活动表征的多种疾病中的至少一种的方法包括将电极定位在由迷走神经支配的身体器官周围。 将电信号施加到电极以调节迷走神经活性。 电信号被施加在为信号选择的频率上，以向迷走神经产生神经传导阻滞，其中神经传导阻滞被选择以至少部分阻断迷走神经上的脉冲。 电信号的应用被停止。 重复信号的应用和信号的中断，并且选择停止和应用的持续时间来治疗疾病。

    Irritable bowel syndrome treatment
    7.
    发明申请
    Irritable bowel syndrome treatment 有权
    肠易激综合征治疗

    公开(公告)号：US20070142870A1

    公开(公告)日：2007-06-21

    申请号：US11656113

    申请日：2007-01-22

    Applicant: Mark Knudson ,  Richard Wilson ,  Katherine Tweden ,  Timothy Conrad

    Inventor： Mark Knudson ,  Richard Wilson ,  Katherine Tweden ,  Timothy Conrad

    IPC: A61N1/36

    CPC classification number: A61N1/36053 ,  A61F5/0026 ,  A61N1/05 ,  A61N1/321 ,  A61N1/36007 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/37235

    Abstract: At least one of a plurality of disorders of a patient characterized at least in part by vagal activity innervating at least one of a plurality of organs of the patient is treated by a method that includes positioning a neurostimulator carrier around a body organ of the patient where the organ is innervated by at least a vagal trunk. An electrode is disposed on the carrier and positioned at the vagal trunk. An electrical signal is applied to the electrode to modulate vagal activity by an amount selected to treat the disorder. The signal may be a blocking or a stimulation signal.

    Abstract translation: 至少部分由至少部分由迷走神经活动支配至少一个患者的多个器官的患者的障碍中的至少一种通过包括将神经刺激器载体定位在患者的身体器官周围的方法来治疗， 器官由至少一个迷走神经树干支配。 电极设置在载体上并位于迷走神经干线处。 将电信号施加到电极，以通过选择用于治疗病症的量来调节迷走神经活性。 该信号可以是阻塞或刺激信号。

    GI inflammatory disease treatment
    8.
    发明申请
    GI inflammatory disease treatment 有权
    GI炎症性疾病治疗

    公开(公告)号：US20070135857A1

    公开(公告)日：2007-06-14

    申请号：US11656122

    申请日：2007-01-22

    Applicant: Mark Knudson ,  Richard Wilson ,  Katherine Tweden ,  Timothy Conrad

    Inventor： Mark Knudson ,  Richard Wilson ,  Katherine Tweden ,  Timothy Conrad

    IPC: A61N1/32

    CPC classification number: A61N1/36053 ,  A61F5/0026 ,  A61N1/05 ,  A61N1/321 ,  A61N1/36007 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/37235

    Abstract: At least one of a plurality of disorders of a patient characterized at least in part by vagal activity innervating at least one of a plurality of organs of the patient is treated by a method that includes positioning a neurostimulator carrier around a body organ of the patient where the organ is innervated by at least a vagal trunk. An electrode is disposed on the carrier and positioned at the vagal trunk. An electrical signal is applied to the electrode to modulate vagal activity by an amount selected to treat the disorder. The signal may be a blocking or a stimulation signal.

    Abstract translation: 至少部分由至少部分由迷走神经活动支配至少一个患者的多个器官的患者的障碍中的至少一种通过包括将神经刺激器载体定位在患者的身体器官周围的方法来治疗， 器官由至少一个迷走神经树干支配。 电极设置在载体上并位于迷走神经干线处。 将电信号施加到电极，以通过选择用于治疗病症的量来调节迷走神经活性。 该信号可以是阻塞或刺激信号。

    Vagal obesity treatment
    9.
    发明申请
    Vagal obesity treatment 审中-公开
    迷走神经肥胖治疗

    公开(公告)号：US20070135846A1

    公开(公告)日：2007-06-14

    申请号：US11656123

    申请日：2007-01-22

    Applicant: Mark Knudson ,  Richard Wilson ,  Katherine Tweden ,  Timothy Conrad

    Inventor： Mark Knudson ,  Richard Wilson ,  Katherine Tweden ,  Timothy Conrad

    IPC: A61N1/32

    CPC classification number: A61N1/36053 ,  A61F5/0026 ,  A61N1/05 ,  A61N1/321 ,  A61N1/36007 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/37235

    Abstract: At least one of a plurality of disorders of a patient characterized at least in part by vagal activity innervating at least one of a plurality of organs of the patient is treated by a method that includes positioning a neurostimulator carrier around a body organ of the patient where the organ is innervated by at least a vagal trunk. An electrode is disposed on the carrier and positioned at the vagal trunk. An electrical signal is applied to the electrode to modulate vagal activity by an amount selected to treat the disorder. The signal may be a blocking or a stimulation signal.

    Abstract translation: 至少部分由至少部分由迷走神经活动支配至少一个患者的多个器官的患者的障碍中的至少一种通过包括将神经刺激器载体定位在患者的身体器官周围的方法来治疗， 器官由至少一个迷走神经树干支配。 电极设置在载体上并位于迷走神经干线处。 将电信号施加到电极，以通过选择用于治疗病症的量来调节迷走神经活性。 该信号可以是阻塞或刺激信号。

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