STREPTOSPIROLE DERIVATIVES
    2.
    发明申请

    公开(公告)号:US20110295009A1

    公开(公告)日:2011-12-01

    申请号:US13056751

    申请日:2009-07-16

    CPC classification number: C07D498/10 C07D491/107

    Abstract: The invention relates to streptospirole derivatives of the general formula (I), wherein R1, R2, R3, X1, X2, Y1 and Y2 are as defined herein, a process for the preparation of said compounds by fermenting the microorganism Streptomyces sp. ST 108140 (DSM 19369) and optionally derivatizing the compounds produced by said microorganism, a pharmaceutical composition comprising at least one compound of the formula (I), and the use of a compound of the formula (I) for the preparation of a medicament for the treatment and/or prophylaxis of bacterial infections.

    Abstract translation: 本发明涉及通式(I)的链霉菌素衍生物,其中R1,R2,R3,X1,X2,Y1和Y2如本文所定义,通过发酵微生物Streptomyces sp。 ST108404(DSM19369),并任选地衍生由所述微生物产生的化合物,包含至少一种式(I)化合物的药物组合物和式(I)化合物在制备药物中的应用 治疗和/或预防细菌感染。

    Aqueous non-ionically stabilized epoxy resins
    3.
    发明授权
    Aqueous non-ionically stabilized epoxy resins 失效
    水性非离子稳定化环氧树脂

    公开(公告)号:US07560143B2

    公开(公告)日:2009-07-14

    申请号:US10531090

    申请日:2003-10-17

    Abstract: Aqueous radiation curable binders comprising non-ionically stabilized epoxy resins ABC. Resins ABC are an adduct mixture of: adducts formed by the reaction of polyethylene glycol-modified epoxy resins A with olefinically unsaturated acids C, and adducts formed by the reaction of epoxy resins B, that are free from polyethylene glycol derived groups, with olefinically unsaturated acids C. A process for preparing aqueous radiation curable binders comprising non-ionically stabilized epoxy resins ABC, and a process of coating a substrate with aqueous radiation curable binders comprising non-ionically stabilized epoxy resins ABC.

    Abstract translation: 包含非离子稳定化环氧树脂ABC的水性可辐射固化粘合剂。 树脂ABC是以下加合物混合物:由聚乙二醇改性的环氧树脂A与烯属不饱和酸C反应形成的加合物,和不含聚乙二醇衍生基团的环氧树脂B与烯属不饱和酸反应形成的加成物 酸C.制备包含非离子稳定化环氧树脂ABC的水性可辐射固化粘合剂的方法,以及用包含非离子稳定化环氧树脂ABC的水性可辐射固化粘合剂涂覆基材的方法。

    Water dilutable amine curing agents for aqueous two component epoxy resin systems
    4.
    发明授权
    Water dilutable amine curing agents for aqueous two component epoxy resin systems 有权
    水可稀释胺固化剂用于水性双组分环氧树脂体系

    公开(公告)号:US06653369B2

    公开(公告)日:2003-11-25

    申请号:US10139461

    申请日:2002-05-06

    CPC classification number: C08G59/184

    Abstract: Water dilutable amine curing agents for aqueous epoxy resin dispersions, comprising a combination of an epoxide-amine adduct with an emulsifier, the epoxide-amine adduct being obtainable by reacting a polyepoxide with a reaction product of an amine and an epoxide component or an amine and subsequent reaction with an epoxide component, the amount of amine being chosen such that the number of nitrogen-attached hydrogen atoms the number of epoxide groups by a factor of from 2 to 10, and the emulsifier being obtainable by reacting diepoxides or polyepoxides with compounds that are at least difunctional with respect to epoxides, optionally with compounds D that are monofunctional with respect to epoxides, and with amines G which contain at least one tertiary and at least one primary or at least two secondary amino group(s).

    Abstract translation: 用于水性环氧树脂分散体的水可稀释胺固化剂,其包括环氧胺 - 胺加合物与乳化剂的组合,所述环氧胺 - 加合物可通过使多环氧化物与胺和环氧化物组分或胺的反应产物反应获得, 随后与环氧化物组分的反应,选择胺的量使得连接氮原子的氢原子数目为2至10的环氧化物基团数,并且乳化剂可通过使二环氧化物或聚环氧化物与化合物 至少对于环氧化物是双官能的,任选地与化合物D相对于环氧化物是单官能的,以及含有至少一个叔胺和至少一个伯或至少两个仲氨基的胺G.

    Anionically stabilized aqueous polyvinylbutyral dispersions and process
for their preparation and use
    5.
    发明授权
    Anionically stabilized aqueous polyvinylbutyral dispersions and process for their preparation and use 失效
    阴离子稳定的聚乙烯醇缩丁醛分散体及其制备和使用方法

    公开(公告)号:US5708074A

    公开(公告)日:1998-01-13

    申请号:US640715

    申请日:1996-05-01

    Abstract: A process for the preparation of water-dilutable polyvinylbutyral dispersions by (1) reacting an aliphatic acid having from one to three isocyanate-reactive groups and from one to three acid groups, or a mixture of such acids, with one or more polyfunctional isocyanates whose average functionality is at least two, where the quantity of the isocyanate component is chosen such that the ratio of the number of isocyanate groups to the number of isocyanate-reactive groups of the acid component is between 2.2:1 and 1.7:1; (2) then reacting from 25 to 75% of the remaining isocyanate groups with at least one monofunctional compound selected from monoalcohols and monoamines; and (3) reacting this NCO-functional emulsifier resin further with polyvinylbutyral and, if desired, with an appropriate plasticizer resin using a suitable auxiliary solvent. The polyvinylbutyral dispersions prepared in this way can be used as binders and binder components for coatings with good adhesion.

    Abstract translation: 通过(1)使具有1至3个异氰酸酯反应性基团和1至3个酸基团的脂族酸或这些酸的混合物与一种或多种多官能异氰酸酯反应来制备水可稀释的聚乙酸缩丁醛分散体的方法,其中 平均官能度为至少两个,其中选择异氰酸酯组分的量使得异氰酸酯基团的数量与酸组分的异氰酸酯 - 反应性基团的数量的比例在2.2:1和1.7:1之间; (2)然后使25至75%剩余的异氰酸酯基团与至少一种选自一元醇和一元胺的单官能化合物反应; 和(3)使该NCO-功能乳化剂树脂进一步与聚乙烯醇缩丁醛反应,如果需要,使用合适的辅助溶剂与适当的增塑剂树脂反应。 以这种方式制备的聚乙烯醇缩丁醛分散体可用作具有良好粘附性的涂料的粘合剂和粘合剂组分。

    Streptospirole derivatives
    6.
    发明授权
    Streptospirole derivatives 有权
    链球菌衍生物

    公开(公告)号:US08765799B2

    公开(公告)日:2014-07-01

    申请号:US13056751

    申请日:2009-07-16

    CPC classification number: C07D498/10 C07D491/107

    Abstract: The invention relates to streptospirole derivatives of the general formula (I), wherein R1, R2, R3, X1, X2, Y1 and Y2 are as defined herein, a process for the preparation of said compounds by fermenting the microorganism Streptomyces sp. ST 108140 (DSM 19369) and optionally derivatizing the compounds produced by said microorganism, a pharmaceutical composition comprising at least one compound of the formula (I), and the use of a compound of the formula (I) for the preparation of a medicament for the treatment and/or prophylaxis of bacterial infections.

    Abstract translation: 本发明涉及通式(I)的链霉菌素衍生物,其中R1,R2,R3,X1,X2,Y1和Y2如本文所定义,通过发酵微生物Streptomyces sp。 ST108404(DSM19369),并任选地衍生由所述微生物产生的化合物,包含至少一种式(I)化合物的药物组合物和式(I)化合物在制备药物中的应用 治疗和/或预防细菌感染。

    Radiation-curable water-dilutable urethane resins, preparation process
and use
    8.
    发明授权
    Radiation-curable water-dilutable urethane resins, preparation process and use 失效
    可辐射固化水可稀释的聚氨酯树脂,制备方法和用途

    公开(公告)号:US5990192A

    公开(公告)日:1999-11-23

    申请号:US57583

    申请日:1998-04-09

    CPC classification number: C09D175/14 C08G18/6705 C08G18/675 Y10T428/31591

    Abstract: Radiation-curable water-dilutable urethane resins obtainable by reacting cycloaliphatic and/or aromatic diisocyanates with a mixture of a (meth)acryloyl-containing dihydroxy compound in an amount such that the amount of reactive hydroxyl groups present therein is from 0.2 to 0.6 mol, and with a tri or tetrahydric polyol which has been partly esterified with (meth)acrylic acid and has a residual average hydroxyl functionality of from 1.0 to 1.4 in the molecule, in an amount such that the amount of the reactive hydroxyl groups is from 0.4 to 0.8 mol, the sum of the amounts of the reactive hydroxyl groups always being 1.0 mol, and from 40 to 60% of the isocyanate groups being converted into urethane groups, and reacting the resulting intermediate with an aliphatic saturated monocarboxylic acid having at least two hydroxyl groups in an amount such that the amount of the reactive hydroxyl groups is from 0.6 to 1 mol, until the hydroxyl groups have undergone complete reaction and reacting this product, if desired, with further part-esterified polyol in an amount such that the amount of hydroxyl groups in the polyol is from 0 to 0.5 mol until the remaining free isocyanate groups have undergone complete reaction, the molar proportions of the components being chosen so that the ratio of the number of isocyanate groups to the number of hydroxyl groups is from 0.9:1 to 1:1 and the reaction product possesses carboxyl groups in accordance with an acid number of from 20 to 40 mg/g and has a specific double bond content of not more than 3.5 mol/kg.

    Abstract translation: 可通过使脂环族和/或芳族二异氰酸酯与含(甲基)丙烯酰基的二羟基化合物的混合物使其中存在的反应性羟基的量为0.2至0.6mol的量反应得到的可辐射固化水可稀释的聚氨酯树脂, 和与(甲基)丙烯酸部分酯化并且在分子中具有1.0至1.4的残余平均羟基官能度的三元或四元多元醇,其量使得反应性羟基的量为0.4至 0.8mol,反应性羟基的总量总计为1.0mol,异氰酸酯基的40-60%转化为氨基甲酸酯基团,并使得到的中间体与具有至少两个羟基的脂族饱和一元羧酸反应 基团的量使得反应性羟基的量为0.6至1mol,直到羟基已经完全反应并使其反应 是产物,如果需要,还有部分酯化的多元醇的量使得多元醇中羟基的量为0至0.5mol,直到剩余的游离异氰酸酯基团经历了完全反应,选择的组分的摩尔比例 使得异氰酸酯基数与羟基数的比例为0.9:1至1:1,并且反应产物具有根据酸值为20至40mg / g的羧基,并且具有特定的 双键含量不超过3.5 mol / kg。

    Aqueous Epoxy Resin Systems
    9.
    发明申请
    Aqueous Epoxy Resin Systems 审中-公开
    水性环氧树脂体系

    公开(公告)号:US20080200599A1

    公开(公告)日:2008-08-21

    申请号:US11665304

    申请日:2005-09-30

    Abstract: An aqueous epoxy resin system ABC comprising an aqueously dispersed epoxy resin A having, on the average, at least one epoxy group per molecule, a water-soluble or water-dispersible curing agent B which comprises the reaction product of an amine B1 having at least one primary and at least one secondary amino group, and an adduct B2 of a polyalkylene ether polyol B21 and an opexide component B22, and aminoplast compound C having a mass fraction of at least 0.1% of sulphonate or sulphonic acid groups, a coating composition ABCD for thick layer applications comprising the aqueous epoxy resin system ABC and at least one particulate filler D selected from the group consisting of talc, mica, quartz, titanium dioxide, aluminium dioxide, calcium carbonate, and dolomite, and a process for coating mineral or concrete based substrates or floors with such coating compositions.

    Abstract translation: 一种水性环氧树脂体系ABC,其包含平均分子量为至少一个环氧基团的高分散环氧树脂A,水溶性或水分散性固化剂B,其包含至少具有胺B1的反应产物 一个伯和至少一个仲氨基,以及聚亚烷基醚多元醇B 21和opexide组分B22的加合物B2和质量分数为至少0.1%的磺酸盐或磺酸基团的氨基塑料化合物C,涂料组合物 用于包括水性环氧树脂体系ABC和至少一种选自滑石,云母,石英,二氧化钛,二氧化铝,碳酸钙和白云石的至少一种颗粒填料D的厚层应用的ABCD,以及用于涂覆矿物或 混凝土基底或具有这种涂层组合物的地板。

    Aqueous anticorrosion primers based on polyvinylbutyral
    10.
    发明授权
    Aqueous anticorrosion primers based on polyvinylbutyral 失效
    基于聚乙烯醇缩丁醛的水性防腐底漆

    公开(公告)号:US06433079B1

    公开(公告)日:2002-08-13

    申请号:US09579172

    申请日:2000-05-25

    CPC classification number: C08F8/30 C08F16/06

    Abstract: Water-dilutable polyvinylbutyral dispersions obtainable by a two-stage reaction in the first stage of which at least one tertiary alkanolamine A and at least one diisocyanate B are reacted to the theoretically calculated NCO content and the amounts of components A and B are chosen such that the amount of substance of the diisocyanates B is from 0.8 to 1.3 times the amount of substance of the reactive hydroxyl groups in A and thereafter in the second stage a polyvinylbutyral C dissolved in a solvent which is inert towards isocyanates is reacted with the adduct AB from the first step to form the product ABC until all of the isocyanate groups have undergone complete reaction, the number of hydroxyl groups in C being at least ten times the number of isocyanate groups in the reaction product AB.

    Abstract translation: 在第一阶段可通过两阶段反应获得的水可稀释的聚乙烯醇缩丁醛分散体,其中至少一种叔烷醇胺A和至少一种二异氰酸酯B与理论计算的NCO含量反应,并且组分A和B的量被选择为使得 二异氰酸酯B的物质的量为A中反应性羟基的物质量的0.8〜1.3倍,此后在第二阶段中,溶解在对异氰酸酯惰性的溶剂中的聚乙烯醇缩丁烷C与加合物AB反应 形成产物ABC的第一步,直到所有的异氰酸酯基团已经完全反应,C中的羟基数量是反应产物AB中异氰酸酯基团数量的至少十倍。

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