公开(公告)号：US20150293923A1

公开(公告)日：2015-10-15

申请号：US14666937

申请日：2015-03-24

Applicant: SEBASTIAN PROBST EIDE ,  PAUL FRANCIS ,  FELIX BAUER ,  MATTHIAS KRETSCHMER ,  CRISTIAN DANIEL BERNEANU ,  SASA JURIC

Inventor： SEBASTIAN PROBST EIDE ,  PAUL FRANCIS ,  FELIX BAUER ,  MATTHIAS KRETSCHMER ,  CRISTIAN DANIEL BERNEANU ,  SASA JURIC

IPC: G06F17/30

CPC classification number: G06F16/24578 ,  G06F16/2228 ,  G06F16/2462 ,  G06F21/6254

Abstract: A computer system includes a database configured to receive a query and to produce a list of User IDs and an anonymization module. The anonymization module is configured to receive a list of user IDs in response to a query, the list of user IDs defining a true user count, generate a noisy user count of the list of user IDs, compare the true user count to a first threshold value stored in memory, compare the noisy user count to a second threshold value stored in memory, and output the noisy user count only if the true user count is greater than the first threshold value and the noisy user count is greater then the second threshold.

Abstract translation: 计算机系统包括被配置为接收查询并产生用户ID列表和匿名模块的数据库。 匿名化模块被配置为响应于查询接收用户ID的列表，定义真实用户计数的用户ID列表，生成用户ID列表的噪声用户计数，将真实用户计数与第一阈值进行比较 存储在存储器中的值，将噪声用户计数与存储在存储器中的第二阈值进行比较，并且仅当真实用户计数大于第一阈值且噪声用户计数大于第二阈值时才输出噪声用户计数。

公开(公告)号：US20110315280A1

公开(公告)日：2011-12-29

申请号：US13145749

申请日：2009-12-12

Applicant: Holger Behrens ,  Klaus Frommann ,  Hans-Georg Hartung ,  Matthias Kretschmer ,  Lutz Kümmel

Inventor： Holger Behrens ,  Klaus Frommann ,  Hans-Georg Hartung ,  Matthias Kretschmer ,  Lutz Kümmel

IPC: C21D8/02 ,  B08B7/00 ,  C21D9/573

CPC classification number: B21B45/04 ,  B21B3/02 ,  C21D9/573

Abstract: A method of annealing and descaling hot-rolled austenitic stainless steel strip wherein. The steel strip is descaled in a connected plasma descaling installation after annealing and subsequent cooling. The plasma descaling is carried out under vacuum in a plurality of stages, and the steel strip is subjected to a controlled cooling between these stages and after the final stage by means of cooling rolls so that the steel strip has a temperature below 100° C. when exiting the plasma descaling installation. An apparatus to practice the method is also disclosed.

Abstract translation: 热轧奥氏体不锈钢带的退火和去氧化皮的方法。 在退火和随后的冷却后，钢带在连接的等离子体除垢装置中除垢。 等离子体除锈在多级的真空下进行，钢带在这些阶段之间和最终阶段之间通过冷却辊进行受控制的冷却，使得钢带的温度低于100℃。 当离开等离子体除垢装置时。 还公开了一种实施该方法的装置。

公开(公告)号：US20100308541A1

公开(公告)日：2010-12-09

申请号：US12445949

申请日：2007-10-12

Applicant: Lutz Kuemmel ,  Andreas Gramer ,  Holger Behrens ,  Matthias Kretschmer ,  Ralf-hartmut Sohl ,  Peter De Kock

Inventor： Lutz Kuemmel ,  Andreas Gramer ,  Holger Behrens ,  Matthias Kretschmer ,  Ralf-hartmut Sohl ,  Peter De Kock

IPC: F16J15/16

CPC classification number: B01J3/006 ,  B01J3/03 ,  B01J2219/00033 ,  F27D99/0073

Abstract: The invention relates to a strip sealing gate (1) for sealing a first chamber (2) with a first pressure level (p1) in relation to a second chamber (3) with a second pressure level (p2) that differs from the first, a strip (4), in particular a metal strip, passing through both chambers (2, 3). According to the invention, at least two rollers (5, 6) are provided for sealing the chambers (2, 3), said rollers resting in a sealing manner on either side of the strip (4). The aim of the invention is to improve the sealing action. To achieve this, at least some sections of the circumference of at least one of the rollers (5, 6) are covered with a flexible elastic material (7) and said roller or rollers (5, 6) have an inner core (8) that is covered with a jacket consisting of the flexible elastic material (7). A central region (9) of the inner core (8) has a cylindrical contour (10) and the edge regions (11, 12) of the core (8) are flared.

Abstract translation: 本发明涉及一种用于密封具有第二压力水平（p1）相对于第二室（3）的第一室（2）的带状密封门（1），其具有与第一室（2）不同的第二压力水平（p2） （4），特别是金属条，穿过两个腔室（2,3）。 根据本发明，提供至少两个辊（5,6）用于密封腔室（2,3），所述辊子以密封方式放置在条带（4）的任一侧上。 本发明的目的是改善密封作用。 为了实现这一点，至少一个辊（5,6）的圆周的至少一些部分被柔性弹性材料（7）覆盖，并且所述辊或辊（5,6）具有内芯（8） 其被柔性弹性材料（7）组成的护套覆盖。 内芯（8）的中心区域（9）具有圆柱形轮廓（10），并且所述芯部（8）的边缘区域（11,12）被展开。

公开(公告)号：US20100096785A1

公开(公告)日：2010-04-22

申请号：US12450640

申请日：2008-02-20

Applicant: Peter de Kock ,  Matthias Kretschmer ,  Holger Behrens

Inventor： Peter de Kock ,  Matthias Kretschmer ,  Holger Behrens

IPC: F27D13/00 ,  F27D3/00

CPC classification number: F27D13/00 ,  C22B9/00 ,  C22B19/32 ,  C23C2/003 ,  F27D3/0025 ,  F27D3/0031 ,  F27D3/0033 ,  F27D99/0006

Abstract: The invention relates to a device (1) for inserting metal ingots (2) into a metal bath (3), in particular zinc ingots into a zinc bath, wherein the device (1) comprises feed means (4) with which an ingot (2) can be fed to the metal bath (3), and wherein the device (1) comprises heating means (5) with which the ingot (2) can be heated to a desired temperature before and/or after its feeding into the metal bath (3). In order to improve the process control, it is provided according to the invention that the heating means (5) comprise at least one independently operated heating element which can be operated independently of other system parts with which the device (1) cooperates.

Abstract translation: 本发明涉及一种用于将金属锭（2）插入金属浴（3）中，特别是锌锭进入锌浴的装置（1），其中装置（1）包括进料装置（4），锭 2）可以被供给到金属浴（3），并且其中装置（1）包括加热装置（5），在其进入金属之前和/或之后，锭可以被加热到期望的温度 浴（3）。 为了改进过程控制，根据本发明提供了加热装置（5）包括至少一个独立操作的加热元件，其可以与设备（1）配合的其它系统部件独立地操作。

公开(公告)号：US20070275481A1

公开(公告)日：2007-11-29

申请号：US10579639

申请日：2004-11-23

Applicant: Elena Vasilyeva ,  Francine Brown ,  Matthias Kretschmer ,  Peter Bove ,  Hans Fajardo ,  Frederick Taylor ,  Rohin Mhatre ,  Kazumi Kobayashi ,  Amy Dingley

Inventor： Elena Vasilyeva ,  Francine Brown ,  Matthias Kretschmer ,  Peter Bove ,  Hans Fajardo ,  Frederick Taylor ,  Rohin Mhatre ,  Kazumi Kobayashi ,  Amy Dingley

IPC: G01N33/561 ,  C07K1/00 ,  C07K14/00 ,  C07K16/18 ,  G01N33/00

CPC classification number: G01N27/447 ,  G01N27/44747 ,  G01N33/6857

Abstract: The invention provides a method of using chip-based gel electrophoresis to determine the presence of polypeptides with selected disulfide linkage patterns, for example, completely formed tetrameric antibodies as compared to incompletely formed heterodimeric half-antibodies. The invention further features a kit, comprising a chip, and instructions for conducting the foregoing method. The methods and kits of the invention are amendable to high throughput applications for the monitoring of production and quality control of recombinant therapeutic antibodies.

Abstract translation: 本发明提供了一种使用基于芯片的凝胶电泳来确定具有选定的二硫键连图谱的多肽的存在，例如完全形成的四聚体抗体与不完全形成的异二聚体半抗体相比。 本发明进一步具有包括芯片的套件和用于进行上述方法的指令。 本发明的方法和试剂盒可修改为用于监测重组治疗性抗体的生产和质量控制的高通量应用。

公开(公告)号：US08728244B2

公开(公告)日：2014-05-20

申请号：US13086678

申请日：2011-04-14

Applicant: Holger Behrens ,  Rolf Brisberger ,  Klaus Adolf Frommann ,  Matthias Kretschmer ,  Rüdiger Zerbe ,  Evgeny Stepanovich Senokosov ,  Andrei Evgenievich Senokosov

Inventor： Holger Behrens ,  Rolf Brisberger ,  Klaus Adolf Frommann ,  Matthias Kretschmer ,  Rüdiger Zerbe ,  Evgeny Stepanovich Senokosov ,  Andrei Evgenievich Senokosov

IPC: B08B6/00

CPC classification number: B08B7/0035 ,  B21B15/005 ,  B21B45/0203 ,  B21B45/04 ,  B21B45/06 ,  C23C2/02

Abstract: A method for descaling a metal strip, in which the metal strip is guided in a direction of conveyance through at least two plasma descaling units, in which it is subjected to a plasma descaling, where the plasma descaling is followed directly or indirectly by an operation in which the metal strip is coated with a coating metal by hot dip galvanizing of the metal strip. The metal strip is coated with the coating metal by a vertical passage process. The coating metal is retained as a coating bath in a coating tank by an electromagnetic seal. The metal strip preheated by the plasma descaling is guided, without exposure to air, from the plasma descaling into a protective gas atmosphere of a continuous furnace necessary for the coating.

Abstract translation: 一种金属带的除鳞方法，其中金属带沿着输送方向通过至少两个等离子体除垢单元被引导，其中进行等离子体除锈，其中等离子体除锈通过操作直接或间接地进行 其中金属带通过金属带的热浸镀锌被涂覆金属涂覆。 金属带通过垂直通道工艺涂覆有金属涂层。 涂覆金属通过电磁密封作为涂层保持在涂布槽中。 通过等离子体除锈来预热的金属带不受空气的影响，从等离子体除锈进入涂覆所需的连续炉的保护气体气氛中。

公开(公告)号：US20120005519A1

公开(公告)日：2012-01-05

申请号：US12827608

申请日：2010-06-30

Applicant: Matthias Kretschmer ,  Ronen Cohen ,  Nimrod Vishnia Shabtai ,  Shachar Sagi ,  Yoram Horowitz

Inventor： Matthias Kretschmer ,  Ronen Cohen ,  Nimrod Vishnia Shabtai ,  Shachar Sagi ,  Yoram Horowitz

IPC: G06F17/30 ,  G06F11/07 ,  G06F3/048

CPC classification number: G06F11/0709 ,  G06F11/0793 ,  G06F11/1415

Abstract: A system and method for providing collaborative master data process management. A master data store comprises data for at least one data domain. A master data management module is configured to provide access to the data to one or more applications. A master data management service module provides at least one service providing access to the data based on a service-oriented architecture. A business process management module is configured to generate, execute and manage at least one business process related to the data domain. The at least one business process uses at least one of the at least one service provided by the master data management service module. A master data process module is configured to generate at least one data process comprising a business process involving an operation on the data.

Abstract translation: 一种用于提供协作主数据流程管理的系统和方法。 主数据存储包括至少一个数据域的数据。 主数据管理模块被配置为向一个或多个应用提供对数据的访问。 主数据管理服务模块基于面向服务的架构提供至少一个提供对数据的访问的服务。 业务流程管理模块被配置为生成，执行和管理与数据域相关的至少一个业务流程。 所述至少一个业务过程使用由主数据管理服务模块提供的至少一个服务中的至少一个。 主数据处理模块被配置为生成包括涉及对数据的操作的业务处理的至少一个数据处理。

公开(公告)号：US20110186224A1

公开(公告)日：2011-08-04

申请号：US13086635

申请日：2011-04-14

Applicant: Holger Behrens ,  Rolf Brisberger ,  Klaus Frommann ,  Matthias Kretschmer ,  Rüdiger Zerbe ,  Evgeny Stepanovich Senokosov ,  Andrei Evgenievich Senokosov

Inventor： Holger Behrens ,  Rolf Brisberger ,  Klaus Frommann ,  Matthias Kretschmer ,  Rüdiger Zerbe ,  Evgeny Stepanovich Senokosov ,  Andrei Evgenievich Senokosov

IPC: C23F1/08

CPC classification number: B08B7/0035 ,  B21B15/005 ,  B21B45/0203 ,  B21B45/04 ,  B21B45/06 ,  C23C2/02

Abstract: A method and a device for descaling a metal strip, in which the metal strip is guided in a direction of conveyance through at least one plasma descaling unit in which it is subjected to a plasma descaling. The metal strip is subjected to an automatically controlled cooling process in a cooling unit following the plasma descaling in the one or more plasma descaling units in such a way that it has a well-defined temperature downstream of the cooling unit.

Abstract translation: 一种用于对金属带进行去氧化皮去除方法和装置，其中金属带沿着输送方向通过至少一个经受等离子体除锈的等离子体除锈单元被引导。 在一个或多个等离子体除垢单元中的等离子体除垢之后，在冷却单元中对金属带进行自动控制的冷却处理，使得其在冷却单元的下游具有明确的温度。

公开(公告)号：US20080210256A1

公开(公告)日：2008-09-04

申请号：US11883034

申请日：2006-02-22

Applicant: Matthias Kretschmer ,  Hans-Georg Hartung

Inventor： Matthias Kretschmer ,  Hans-Georg Hartung

IPC: B08B3/12 ,  B08B13/00

CPC classification number: C23G3/027 ,  B08B3/022 ,  B08B3/12 ,  B08B3/123 ,  B21B45/0275 ,  C23G3/023

Abstract: The invention relates to a method of a cleaning a metal strip (1). In order to improve the cleaning of the strip, according to the invention, it is provided that the metal strip (1) is first subjected to a first high-pressure cleaning (4) with at least one liquid jet in a first region (2) of a cleaning device (3), and in that the metal strip (1) thereafter is subjected to an ultrasonic cleaning (6) in a second region off the cleaning device (3), at which the metal strip (1) is displaced through a container filled with liquid. The invention further relates to a device for cleaning a metal strip.

Abstract translation: 本发明涉及清洗金属条（1）的方法。 为了改进条的清洁，根据本发明，提供金属条（1）首先在第一区域（2）中进行至少一个液体射流的第一高压清洁（4） ），并且此后的金属带（1）在清洁装置（3）的第二区域中进行超声波清洗（6），在金属带（1）移位的第二区域 通过装满液体的容器。 本发明还涉及一种用于清洁金属条的装置。

公开(公告)号：US08463755B2

公开(公告)日：2013-06-11

申请号：US12827608

申请日：2010-06-30

Applicant: Matthias Kretschmer ,  Ronen Cohen ,  Nimrod Vishnia Shabtai ,  Shachar Sagi ,  Yoram Horowitz

Inventor： Matthias Kretschmer ,  Ronen Cohen ,  Nimrod Vishnia Shabtai ,  Shachar Sagi ,  Yoram Horowitz

IPC: G06F7/00 ,  G06F17/30

CPC classification number: G06F11/0709 ,  G06F11/0793 ,  G06F11/1415

Abstract: A system and method for providing collaborative master data process management. A master data store comprises data for at least one data domain. A master data management module is configured to provide access to the data to one or more applications. A master data management service module provides at least one service providing access to the data based on a service-oriented architecture. A business process management module is configured to generate, execute and manage at least one business process related to the data domain. The at least one business process uses at least one of the at least one service provided by the master data management service module. A master data process module is configured to generate at least one data process comprising a business process involving an operation on the data.

Abstract translation: 一种用于提供协作主数据流程管理的系统和方法。 主数据存储包括至少一个数据域的数据。 主数据管理模块被配置为向一个或多个应用提供对数据的访问。 主数据管理服务模块基于面向服务的架构提供至少一个提供对数据的访问的服务。 业务流程管理模块被配置为生成，执行和管理与数据域相关的至少一个业务流程。 所述至少一个业务过程使用由主数据管理服务模块提供的至少一个服务中的至少一个。 主数据处理模块被配置为生成包括涉及对数据的操作的业务处理的至少一个数据处理。