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1.发明申请公开(公告)号：US20150209416A1
公开(公告)日：2015-07-30
申请号：US14606862
申请日：2015-01-27
申请人： Steven B. Puntenney , Neil E. Forsberg , James D. Chapman , Kevin DeHaan , Troy Wistuba , Derek McLean , David Calabotta , Shelby Armstrong , Jennifer Branson
发明人： Steven B. Puntenney , Neil E. Forsberg , James D. Chapman , Kevin DeHaan , Troy Wistuba , Derek McLean , David Calabotta , Shelby Armstrong , Jennifer Branson
IPC分类号： A61K38/47 , A61K33/06 , A61K31/702 , A61K31/716 , A23K1/16 , A61K31/424 , A61K31/57 , A61K31/55 , A23K1/165 , A23K1/175 , A61K33/00 , A61K31/351
CPC分类号： A61K38/47 , A23K20/163 , A23K20/168 , A23K20/184 , A23K20/189 , A23K20/195 , A23K20/28 , A23K50/10 , A61K31/137 , A61K31/35 , A61K31/444 , A61K31/55 , A61K31/57 , A61K31/702 , A61K31/7048 , A61K31/715 , A61K31/716 , A61K33/00 , A61K33/06 , A61K45/06 , C12Y302/01006 , A61K2300/00 , A61K31/351
摘要： Embodiments of a composition comprising silica, mineral clay, mannans, or any combination thereof are disclosed. The composition may further comprise glucan. The composition is administered to an animal that will be administered, or has been administered, a growth promotant. The growth promotant may be a β-agonist, antibiotic, steroid or hormone. The composition is fed to the animal for a period of time before administration of the growth promotant, during administration of the growth promotant, and/or after administration of the growth promotant. Administration of the composition to the animal ameliorates, or prevents development of, at least one deleterious symptom or sign, such as a deleterious symptom or sign potentially associated with administration of the growth promotant. Embodiments of a composition comprising (i) a growth promotant and (ii) glucan, silica, mineral clay, mannans, or any combination thereof also are disclosed.
摘要翻译： 公开了包含二氧化硅，矿物粘土，甘露聚糖或其任何组合的组合物的实施方案。 组合物还可以包含葡聚糖。 将组合物施用于将被施用或已经施用生长促进剂的动物。 生长促进剂可能是一种“激动剂”，“抗生素”，类固醇或激素。 在施用生长促进剂之前，在施用生长促进剂和/或施用生长促进剂之后，将组合物喂给动物一段时间。 向动物施用组合物可改善至少一种有害症状或体征的发展，例如可能与施用生长促进剂相关的有害症状或体征。 还公开了包含（i）生长促进剂和（ii）葡聚糖，二氧化硅，矿物粘土，甘露聚糖或其任何组合的组合物的实施方案。
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2.发明申请USE OF BETA-1,3 (4)-ENDOGLUCANOHYDROLASE, BETA-1,3 (4)-GLUCAN, DIATOMACEOUS EARTH, MINERAL CLAY AND GLUCOMANNAN TO AUGMENT IMMUNE FUNCTION 有权BETA-1,3（4）-ENDOGLUCANOHYDROLASE，BETA-1,3（4）-GLUCAN，DIATOMACEOUS EARTH，MINERAL CLAY AND GLUCOMANNAN TO AUGMENT IMMUNE FUNCTION公开(公告)号：US20130017211A1
公开(公告)日：2013-01-17
申请号：US13566433
申请日：2012-08-03
CPC分类号： A61K38/47 , A23K20/00 , A23K20/163 , A23K20/189 , A23K20/20 , A23K20/28 , A23K50/10 , A23K50/75 , A23L29/015 , A23L29/03 , A23L29/06 , A23L29/294 , A23L33/10 , A23L33/16 , A23V2200/324 , A23V2250/15 , A23V2250/156 , A23V2250/5034 , A23V2250/5058 , A61K31/715 , A61K31/716 , A61K31/736 , A61K33/00 , A61K33/06 , A61K35/02 , A61K38/46 , C12Y302/01006 , A61K2300/00
摘要： A method for the augmentation of immune function is described. The invention comprises a combination of β-1,3 (4)-endoglucanohydrolase, β-1,3 (4)-glucan, diatomaceous earth, mineral clay and glucomannan, which is fed to or consumed by mammalian or avian species in amounts sufficient to augment immune function. The invention described may be admixed with feeds or foods, incorporated into pelleted feeds or foods or administered orally to mammalian and avian species.
摘要翻译： 描述了增加免疫功能的方法。 本发明包括由哺乳动物或禽类物种喂养或消耗的β-谷氨酸-1,3（4） - 内葡聚糖水解酶，β-谷氨酸，-1,3（4） - 葡聚糖，硅藻土，矿物粘土和葡甘露聚糖的组合 足以增加免疫功能的量。 所描述的发明可以与饲料或食品混合，并入到颗粒饲料或食物中或者口服哺乳动物和禽类物种。
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3.发明授权Use of beta-1,3 (4)-endoglucanohydrolase, beta-1,3 (4)-glucan, diatomaceous earth, mineral clay and glucomannan to augment immune function 有权使用β-1,3（4） - 内葡聚糖水解酶，β-1,3（4）葡聚糖，硅藻土，矿物粘土和葡甘露聚糖来增强免疫功能公开(公告)号：US08568715B2
公开(公告)日：2013-10-29
申请号：US13566433
申请日：2012-08-03
IPC分类号： A61K38/47
CPC分类号： A61K38/47 , A23K20/00 , A23K20/163 , A23K20/189 , A23K20/20 , A23K20/28 , A23K50/10 , A23K50/75 , A23L29/015 , A23L29/03 , A23L29/06 , A23L29/294 , A23L33/10 , A23L33/16 , A23V2200/324 , A23V2250/15 , A23V2250/156 , A23V2250/5034 , A23V2250/5058 , A61K31/715 , A61K31/716 , A61K31/736 , A61K33/00 , A61K33/06 , A61K35/02 , A61K38/46 , C12Y302/01006 , A61K2300/00
摘要： A method for the augmentation of immune function is described. The invention comprises a combination of β-1,3 (4)-endoglucanohydrolase, β-1,3 (4)-glucan, diatomaceous earth, mineral clay and glucomannan, which is fed to or consumed by mammalian or avian species in amounts sufficient to augment immune function. The invention described may be admixed with feeds or foods, incorporated into pelleted feeds or foods or administered orally to mammalian and avian species.
摘要翻译： 描述了增加免疫功能的方法。 本发明包括β-1,3（4） - 内葡聚糖水解酶，β-1,3（4）葡聚糖，硅藻土，矿物粘土和葡甘露聚糖的组合，其以足够的量以哺乳动物或禽类物种进食或消耗 增强免疫功能。 所描述的发明可以与饲料或食品混合，并入到颗粒饲料或食物中或者口服哺乳动物和禽类物种。
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4.发明授权Use of β-1,3 (4)-endoglucanohydrolase, β-1,3 (4) glucan, diatomaceous earth, mineral clay and glucomannan to augment immune function 有权使用＆bgr; -1,3（4） - 内葡聚糖水解酶，＆bgr; -1,3（4）葡聚糖，硅藻土，矿物粘土和葡甘露聚糖以增强免疫功能公开(公告)号：US08236303B2
公开(公告)日：2012-08-07
申请号：US11668375
申请日：2007-01-29
IPC分类号： A61K38/47
CPC分类号： A61K38/47 , A23K20/00 , A23K20/163 , A23K20/189 , A23K20/20 , A23K20/28 , A23K50/10 , A23K50/75 , A23L29/015 , A23L29/03 , A23L29/06 , A23L29/294 , A23L33/10 , A23L33/16 , A23V2200/324 , A23V2250/15 , A23V2250/156 , A23V2250/5034 , A23V2250/5058 , A61K31/715 , A61K31/716 , A61K31/736 , A61K33/00 , A61K33/06 , A61K35/02 , A61K38/46 , C12Y302/01006 , A61K2300/00
摘要： A method for the augmentation of immune function is described. The invention comprises a combination of β-1,3(4)-endoglucanohydrolase, β-1,3(4)glucan, diatomaceous earth, mineral clay and glucomannan, which is fed to or consumed by mammalian or avian species in amounts sufficient to augment immune function. The invention described may be admixed with feeds or foods, incorporated into pelleted feeds or foods or administered orally to mammalian and avian species.
摘要翻译： 描述了增加免疫功能的方法。 本发明包括以哺乳动物或禽类物种进食或消耗的量的β-谷氨酸-1,3（4） - 内葡聚糖水解酶，β-葡聚糖，1,3（4）葡聚糖，硅藻土，矿物粘土和葡甘露聚糖的组合， 足以增强免疫功能。 所描述的发明可以与饲料或食品混合，并入到颗粒饲料或食物中或者口服哺乳动物和禽类物种。
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公开(公告)号：US07598061B2
公开(公告)日：2009-10-06
申请号：US11724596
申请日：2007-03-14
CPC分类号： C12Q1/6895 , C12Q2600/16
摘要： Methods are disclosed for detecting, quantifying and/or identifying a fungal species in a sample or for diagnosing jejunal hemorrhage syndrome in a subject. The methods generally include amplifying a fungal nucleic acid sequence present in the sample using a primer selected from the group consisting of: SEQ. ID NO 5, SEQ. ID NO 6, SEQ. ID NO 7, SEQ. ID NO 8, SEQ. ID NO 9, SEQ. ID NO 10, SEQ. ID NO 11, SEQ. ID NO 12, SEQ. ID NO 13, SEQ. ID NO 14 or SEQ. ID NO 16; and observing or measuring the amplified nucleic acid sequence. The fungal species can thereby be detected, quantified, and/or identified. Fungal contamination also can be detected or measured in a biological or feed or food sample.
摘要翻译： 公开了用于检测，定量和/或鉴定样品中的真菌物种或用于诊断受试者的空肠出血综合征的方法。 所述方法通常包括使用选自以下的引物扩增样品中存在的真菌核酸序列：SEQ ID NO： ID NO 5，SEQ。 ID NO 6，SEQ。 ID NO 7，SEQ。 ID NO 8，SEQ。 ID NO 9，SEQ。 ID NO 10，SEQ。 ID NO 11，SEQ。 ID NO 12，SEQ。 ID NO 13，SEQ。 ID NO 14或SEQ。 ID NO 16; 观察或测量扩增的核酸序列。 因此可以检测，量化和/或鉴定真菌物种。 也可以在生物或饲料或食品样品中检测或测量真菌污染物。
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公开(公告)号：US08142798B2
公开(公告)日：2012-03-27
申请号：US11380359
申请日：2006-04-26
CPC分类号： A61K39/39 , A23K10/16 , A23K20/147 , A61K31/715 , A61K31/716 , A61K31/736 , A61K35/02 , A61K38/47 , A61K39/02 , Y02A50/463 , A61K2300/00
摘要： The disclosure relates to a composition added to animal feed used in combination with a vaccine to enhance the effectiveness of the vaccine. Amongst other effects, the composition raises the titer of antibodies to the vaccine.
摘要翻译： 本公开涉及添加到动物饲料中的组合物，其与疫苗组合以增强疫苗的有效性。 除了其他效果之外，组合物还提高了疫苗的抗体滴度。
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