Polarimetry
    1.
    发明授权
    Polarimetry 失效
    偏光镜

    公开(公告)号:US07385695B2

    公开(公告)日:2008-06-10

    申请号:US10497372

    申请日:2003-01-20

    IPC分类号: G01J4/00

    摘要: The present invention relates to an assembly and method for measuring the optical activity of a stimulus of interest. The assembly comprises a source of incident electromagnetic radiation (1), a lens arrangement (2), an input polariser (3), a planar waveguide structure (4) (or an optical fiber), an output polariser (5), a lens arrangement (6) for focussing the output electromagnetic radiation and a detector. The polarisation of the incident electromagnetic radiation relative to the planar waveguide structure (4) is determined by the input polariser (3). The planar waveguide structure in this embodiment comprises a silicon substrate layer (4c) and an absorbent layer (4e). The silicon oxynitride layer (4c) acts as the reference waveguide and the absorbent layer (4e) acts as the sensing waveguide. The sensing waveguide (4e) is exposed in the localised environment (8) to a sample containing the stimulus of interest which is optically active. The adjusted attitude of the output polariser (5) is directly proportional to the optical activity of the stimulus of interest.

    摘要翻译: 本发明涉及一种用于测量感兴趣的刺激物的光学活性的装配和方法。 该组件包括入射电磁辐射源(1),透镜装置(2),输入偏振器(3),平面波导结构(4)(或光纤),输出偏振器(5),透镜 用于聚焦输出电磁辐射的装置(6)和检测器。 入射电磁辐射相对于平面波导结构(4)的极化由输入偏振器(3)确定。 该实施例中的平面波导结构包括硅衬底层(4c)和吸收层(4e)。 氮氧化硅层(4c)用作参考波导,吸收层(4e)用作感测波导。 感测波导(4e)在局部环境(8)中暴露于含有光学活性的感兴趣刺激物的样品。 输出偏振器(5)的调整态度与感兴趣的刺激的光学活动成正比。

    Microelectrode system
    3.
    发明授权
    Microelectrode system 有权
    微电极系统

    公开(公告)号:US06811663B1

    公开(公告)日:2004-11-02

    申请号:US09700649

    申请日:2001-05-21

    IPC分类号: G01N2730

    摘要: A microelectrode system suitable for use in preparative and analytical chemistry having a laminated structure with one or more apertures. In one embodiment a microelectrode system (1) comprises alternating layers of conductor (3) and dielectric (or insulator) (4). The laminated structure (2) comprises two conductor layers (3) and two dielectric layers (4) formed on a base (5) of silicon or a polymeric material. The conducting layers (3) form electrodes in the microelectrodes system (1). The laminated structure has formed within it an aperture in the form of a well (6) being open at one end (7) and closed at the opposite end (8). In another embodiment, the apertures take the form of through holes.

    摘要翻译: 适用于具有一个或多个孔的层压结构的制备和分析化学中的微电极系统。 在一个实施例中,微电极系统(1)包括导体(3)和电介质(或绝缘体)(4)的交替层。 层压结构(2)包括形成在硅或聚合物材料的基底(5)上的两个导体层(3)和两个电介质层(4)。 导电层(3)在微电极系统(1)中形成电极。 层压结构在其中形成为在一端(7)处开口并在相对端(8)处封闭的孔(6)形式的孔。 在另一个实施例中,孔呈通孔的形式。

    Electrode assembly
    5.
    发明授权
    Electrode assembly 有权
    电极组件

    公开(公告)号:US09097654B2

    公开(公告)日:2015-08-04

    申请号:US13130878

    申请日:2009-11-30

    IPC分类号: C25B11/03 C25B11/02 G01N27/30

    摘要: The present invention relates to an electrode assembly having a laminate structure comprising: a first insulating capping layer; a first conducting layer capped by the first insulating capping layer and substantially sandwiched by at least the first insulating capping layer such as to leave exposed only an electrical contact lip of the first conducting layer; and an array of etched voids extending through at least the first insulating capping layer and the first conducting layer, wherein each void is partly bound by a surface of the first conducting layer which acts as an internal submicron electrode.

    摘要翻译: 本发明涉及具有层叠结构的电极组件,包括:第一绝缘覆盖层; 第一导电层被第一绝缘覆盖层覆盖,并且至少基本上被第一绝缘覆盖层夹持,以便仅露出第一导电层的电接触唇; 以及延伸穿过至少第一绝缘覆盖层和第一导电层的蚀刻空隙的阵列,其中每个空隙部分地由作为内部亚微米电极的第一导电层的表面结合。

    Method of identifying analytes
    6.
    发明授权
    Method of identifying analytes 失效
    识别分析物的方法

    公开(公告)号:US5885844A

    公开(公告)日:1999-03-23

    申请号:US617769

    申请日:1996-08-05

    摘要: A method of identifying an analyte, using a chemical sensor (e.g., a piezoelectric crystal oscillator) which produces an output frequency responsive to different analytes by a characteristic change in the output frequency. The sensor is exposed to a step change (to) in concentration of the analyte and the resulting frequency characteristic measured. An expression for this characteristic is derived consisting of two exponential functions (F, S), one (F) derived from the early part of the frequency characteristic and the other (S) from the latter part. The four parameters (A.sub.2, A.sub.3, A.sub.4, A.sub.5) resulting from the functions so obtained are characteristic of the particular analyte.

    摘要翻译: PCT No.PCT / GB93 / 01985 Sec。 371日期:1996年8月5日 102(e)日期1996年8月5日PCT提交1993年9月21日PCT公布。 公开号WO95 / 08765 日期1995年3月30日使用化学传感器(例如压电晶体振荡器)鉴定分析物的方法,其通过输出频率的特性变化产生响应于不同分析物的输出频率。 传感器暴露于分析物浓度的阶跃变化(和),并且测量得到的频率特性。 该特征的表达式由两个指数函数(F,S),一个(F)从频率特性的早期部分导出,另一个(S)来自后一部分。 由这样获得的功能产生的四个参数(A2,A3,A4,A5)是特定分析物的特征。

    Sensor device
    7.
    发明授权
    Sensor device 失效
    传感器装置

    公开(公告)号:US07062110B2

    公开(公告)日:2006-06-13

    申请号:US10344799

    申请日:2001-08-14

    IPC分类号: G02B6/00

    摘要: The present invention relates to a sensor device and method for measuring a property associated with the introduction of or changes in a chemical, biological or physical stimulus in a localized environment, in particular to a sensor device and method for measuring the partition coefficient of a chemical stimulus such as a pharmaceutical compound.

    摘要翻译: 本发明涉及一种用于测量与局部环境中的化学,生物或物理刺激的引入或改变相关的性质的传感器装置和方法,特别涉及一种用于测量化学物质的分配系数的传感器装置和方法 刺激如药物化合物。

    Device for housing a planar optical component
    8.
    发明授权
    Device for housing a planar optical component 失效
    用于容纳平面光学部件的装置

    公开(公告)号:US06701032B1

    公开(公告)日:2004-03-02

    申请号:US09701821

    申请日:2001-04-02

    IPC分类号: G02B600

    摘要: A device for housing a planar optical component such as a chemical sensor comprising a holder for mounting a planar optical component, a housing adapted to receive internally said holder along a longitudinal axis, and guiding means for correlating the position of said planar optical component and of a source of electromagnetic radiation when said holder is located within said housing.

    摘要翻译: 一种用于容纳诸如化学传感器的平面光学部件的装置,包括用于安装平面光学部件的保持器,适于沿着纵向轴线在内部容纳所述保持器的壳体,以及用于使所述平面光学部件的位置和 当所述保持器位于所述壳体内时,电磁辐射源。