2-Thioethenyl substituted carbapenem derivatives
    1.
    发明申请
    2-Thioethenyl substituted carbapenem derivatives 失效
    2-噻吩基取代的碳青霉烯衍生物

    公开(公告)号:US20070004700A1

    公开(公告)日:2007-01-04

    申请号:US11401892

    申请日:2006-04-12

    IPC分类号: A61K31/407 C07D487/04

    CPC分类号: C07D487/04

    摘要: [Objective] An objective of the present invention is to provide compounds that are effective against various resistant bacteria which cause current clinical problems, for example, pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including bata-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis. [Structure] The present invention provides 2-ethenylthio-based carbapenem derivatives represented by the formula (I) or pharmaceutically acceptable salts thereof that are effective, for example, against pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis:

    摘要翻译: [目的]本发明的目的是提供对于引起目前临床问题的各种抗性细菌有效的化合物,例如包括耐青霉素的肺炎链球菌(PRSP),流感嗜血杆菌,包括不产生氨苄青霉素的bata-内酰胺酶的肺炎球菌 流感嗜血杆菌(BLNAR)和莫拉氏菌(布拉汉氏菌)卡他氏菌。 [结构]本发明提供了式(I)表示的2-乙烯基硫代碳青霉烯衍生物或其药学上可接受的盐,其可有效地例如针对包括耐青霉素的肺炎链球菌(PRSP)在内的肺炎球菌,包括β-内酰胺酶的流感嗜血杆菌 - 非生产氨苄青霉素耐药性流感嗜血杆菌(BLNAR)和莫拉氏菌(Branhamella)卡他性:

    Skin-covered lid
    2.
    发明授权
    Skin-covered lid 失效
    皮肤盖子

    公开(公告)号:US5715966A

    公开(公告)日:1998-02-10

    申请号:US623788

    申请日:1996-03-29

    CPC分类号: B60R7/06 B32B3/02

    摘要: A skin covered lid consists of a substrate portion made from resin and a skin layer bonded onto the surface of the substrate portion. The substrate portion has a ceiling portion and side wall portions add also a boss for mounting a lock-plate. The side wall portions have a thickness generally larger than that of the ceiling portion and moreover have hollow portions and also have a hinge portion. The skin layer is fixed with its end portion contacting the side wall portion of the substrate portion.

    摘要翻译: 皮肤覆盖的盖由由树脂制成的基底部分和粘合到基底部分的表面上的皮肤层组成。 基板部分具有顶部,侧壁部分还增加了用于安装锁定板的凸台。 侧壁部分的厚度通常大于顶部的厚度,并且还具有中空部分并且还具有铰链部分。 表层被固定,其端部接触基片部分的侧壁部分。

    Process for the production of an optical fiber bundle for heat
resistance and vacuum resistance by bonding fiber ends with a bonding
glass
    3.
    发明授权
    Process for the production of an optical fiber bundle for heat resistance and vacuum resistance by bonding fiber ends with a bonding glass 失效
    通过用粘合玻璃将纤维端部粘合而制造耐热性和真空度的光纤束的方法

    公开(公告)号:US5472471A

    公开(公告)日:1995-12-05

    申请号:US332044

    申请日:1994-11-01

    IPC分类号: G02B6/04 C03B23/20

    CPC分类号: G02B6/04

    摘要: An optical fiber bundle for heat resistance and vacuum resistance which can be used even at a very high temperature or high vacuum is provided in economical manner. This is accomplished by a process for the production of an optical fiber bundle for heat resistance and vacuum resistance, which comprises making up optical fiber filaments each having a core part and a clad part into a bundle, closely fusion-bonding the end of the optical fiber bundle with a bonding glass and then subjecting the bonding glass to a crystallization treatment to increase the heat resistance.

    摘要翻译: 经济地提供即使在非常高的温度或高真空下也可使用的耐热性和真空度的光纤束。 这是通过生产用于耐热性和真空电阻的光纤束的方法实现的,其包括将具有芯部分和包层部分的光纤丝组成束,将光纤的端部紧密地熔接 纤维束和粘合玻璃,然后对粘合玻璃进行结晶处理以提高耐热性。

    2-thioethenyl substituted carbapenem derivatives
    4.
    发明授权
    2-thioethenyl substituted carbapenem derivatives 失效
    2-硫代乙烯基取代的碳青霉烯衍生物

    公开(公告)号:US07687490B2

    公开(公告)日:2010-03-30

    申请号:US11401892

    申请日:2006-04-12

    CPC分类号: C07D487/04

    摘要: An objective of the present invention is to provide compounds that are effective against various resistant bacteria which cause current clinical problems, for example, pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including bata-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis.The present invention provides 2-ethenylthio-based carbapenem derivatives represented by the formula (I) or pharmaceutically acceptable salts thereof that are effective, for example, against pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus influenzae including beta-lactamase-nonproducing ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis:

    摘要翻译: 本发明的目的是提供对于引起当前临床问题的各种耐药性细菌有效的化合物,例如包括耐青霉素的肺炎链球菌(PRSP),流感嗜血杆菌(Haemophilus influenzae),包括不含巴生酵母的氨苄青霉素抗性流感嗜血杆菌 BLNAR)和莫拉氏菌(Branhamella)卡他氏菌。 本发明提供了由式(I)表示的2-乙烯基硫代碳青霉烯衍生物或其药学上可接受的盐,其可有效地例如针对包括耐青霉素的肺炎链球菌(PRSP)在内的肺炎球菌,流感嗜血杆菌,包括β-内酰胺酶非生产氨苄青霉素 耐药性流感嗜血杆菌(BLNAR)和莫拉氏菌(Branhamella)卡他性:

    Molding method for resin articles
    5.
    发明授权
    Molding method for resin articles 失效
    树脂制品的成型方法

    公开(公告)号:US5804117A

    公开(公告)日:1998-09-08

    申请号:US915082

    申请日:1997-08-20

    摘要: A molded article has a resinous substrate body, and an elastic sheet material, at least partially fused thereto. For molding, the pre-formed elastic sheet material is oriented so as to be in contact with a setting face of an open mold. Further, a molten resin material is injected into a cavity defined within the closed mold via a gate so that the cavity is filled with the resin material. The gate has a substantially thin, rectangular shape in cross-section, and forms a rib integral with and projecting rearwardly from the molded resin substrate body. The integrally formed rib is molded from resin material left remaining in the gate after the molten resin material is injected into the cavity.

    摘要翻译: 模制品具有至少部分地熔合到其上的树脂基材和弹性片材。 为了模制,预成形的弹性片材定向成与开模的设置面接触。 此外,将熔融树脂材料经由浇口注入限定在封闭模具内的空腔中,使得空腔填充有树脂材料。 该浇口的横截面形状基本上是薄的矩形,形成与模制的树脂基体一体并与其成一体的肋。 在将熔融树脂材料注入到空腔中之后,一体形成的肋由残留在浇口中的树脂材料模制而成。

    Method for manufacturing in-mold coating product
    8.
    发明申请
    Method for manufacturing in-mold coating product 失效
    制造模内涂层产品的方法

    公开(公告)号:US20050116384A1

    公开(公告)日:2005-06-02

    申请号:US10999193

    申请日:2004-11-30

    摘要: A method for molding an in-mold coating product including a substrate and a coating formed on a surface of the substrate. A first mold including a fixed mold piece is closed to form a substrate cavity therein. The substrate cavity is charged with a resin to form the substrate with a seal projection formed near the parting line of the first mold. Then, a second mold, which uses the fixed mold piece of the first mold, is closed with the substrate arranged on the fixed mold piece to form a coating cavity therein. The second mold deforms the seal projection so that when a coating material is charged into the coating cavity, the coating material does not leak out toward the parting line of the second mold.

    摘要翻译: 一种成型模内涂料的方法,包括在基材表面上形成的基材和涂层。 包括固定模具的第一模具被封闭以在其中形成衬底空腔。 用树脂填充衬底空腔以形成衬底,其中密封突起形成在第一模具的分型线附近。 然后,使用第一模具的固定模具片的第二模具用布置在固定模具上的基板封闭,以在其中形成涂覆空腔。 第二模具使密封突起变形,使得当涂料被填充到涂层腔中时,涂层材料不会朝向第二模具的分型线泄漏。

    Method for manufacturing in-mold coating product
    10.
    发明授权
    Method for manufacturing in-mold coating product 失效
    制造模内涂层产品的方法

    公开(公告)号:US07459114B2

    公开(公告)日:2008-12-02

    申请号:US10999193

    申请日:2004-11-30

    IPC分类号: B29C45/14 B29C45/16

    摘要: A method for molding an in-mold coating product including a substrate and a coating formed on a surface of the substrate. A first mold including a fixed mold piece is closed to form a substrate cavity therein. The substrate cavity is charged with a resin to form the substrate with a seal projection formed near the parting line of the first mold. Then, a second mold, which uses the fixed mold piece of the first mold, is closed with the substrate arranged on the fixed mold piece to form a coating cavity therein. The second mold deforms the seal projection so that when a coating material is charged into the coating cavity, the coating material does not leak out toward the parting line of the second mold.

    摘要翻译: 一种成型模内涂料的方法,包括在基材表面上形成的基材和涂层。 包括固定模具的第一模具被封闭以在其中形成衬底空腔。 用树脂填充衬底空腔以形成衬底,其中密封突起形成在第一模具的分型线附近。 然后,使用第一模具的固定模具片的第二模具用布置在固定模具上的基板封闭,以在其中形成涂覆空腔。 第二模具使密封突起变形,使得当涂料被填充到涂层腔中时,涂层材料不会朝向第二模具的分型线泄漏。